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There are 2699 results for: content related to: Efficacy and immunomodulatory actions of ONO -4641, a novel selective agonist for sphingosine 1-phosphate receptors 1 and 5, in preclinical models of multiple sclerosis

  1. You have free access to this content
    Sphingosine-1-phosphate receptor type 1 regulates glioma cell proliferation and correlates with patient survival

    International Journal of Cancer

    Volume 126, Issue 10, 15 May 2010, Pages: 2341–2352, Yuya Yoshida, Mitsutoshi Nakada, Naotoshi Sugimoto, Tomoya Harada, Yasuhiko Hayashi, Daisuke Kita, Naoyuki Uchiyama, Yutaka Hayashi, Akihiro Yachie, Yoh Takuwa and Jun-ichiro Hamada

    Article first published online : 6 OCT 2009, DOI: 10.1002/ijc.24933

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    Palmitoylation of the sphingosine 1-phosphate receptor S1P1 is involved in its signaling functions and internalization

    Genes to Cells

    Volume 14, Issue 8, August 2009, Pages: 911–923, Yusuke Ohno, Ayako Ito, Ren Ogata, Yuki Hiraga, Yasuyuki Igarashi and Akio Kihara

    Article first published online : 10 JUL 2009, DOI: 10.1111/j.1365-2443.2009.01319.x

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    Pharmacological relevance and potential of sphingosine 1-phosphate in the vascular system

    British Journal of Pharmacology

    Volume 163, Issue 6, July 2011, Pages: 1140–1162, Mirjam Schuchardt, Markus Tölle, Jasmin Prüfer and Markus van der Giet

    Article first published online : 27 JUN 2011, DOI: 10.1111/j.1476-5381.2011.01260.x

  4. S1P1 deletion in oligodendroglial lineage cells: Effect on differentiation and myelination


    Volume 64, Issue 4, April 2016, Pages: 570–582, Danuta E. Dukala and Betty Soliven

    Article first published online : 11 DEC 2015, DOI: 10.1002/glia.22949

  5. Pharmacophore-Based Design of Novel Oxadiazoles as Selective Sphingosine-1-phosphate (S1P) Receptor Agonists with in vivo Efficacy


    Volume 10, Issue 4, April 2015, Pages: 688–714, Dr. Anna Quattropani, Dr. Wolfgang H. B. Sauer, Dr. Stefano Crosignani, Jerome Dorbais, Dr. Patrick Gerber, Jerome Gonzalez, Delphine Marin, Dr. Mathilde Muzerelle, Fanny Beltran, Dr. Anthony Nichols, Dr. Katrin Georgi, Dr. Manfred Schneider, Dr. Pierre-Alain Vitte, Valerie Eligert, Laurence Novo-Perez, Jennifer Hantson, Sebastien Nock, Dr. Susanna Carboni, Dr. Adriano Luis Soares de Souza, Dr. Jean-François Arrighi, Dr. Ursula Boschert and Dr. Agnes Bombrun

    Article first published online : 3 MAR 2015, DOI: 10.1002/cmdc.201402557

  6. Modulating tone: the overture of S1P receptor immunotherapeutics

    Immunological Reviews

    Volume 223, Issue 1, June 2008, Pages: 221–235, Hugh Rosen, Pedro Gonzalez-Cabrera, David Marsolais, Stuart Cahalan, Anthony S. Don and M. Germana Sanna

    Article first published online : 8 JUL 2008, DOI: 10.1111/j.1600-065X.2008.00645.x

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    Expression patterns of the lysophospholipid receptor genes during mouse early development

    Developmental Dynamics

    Volume 237, Issue 11, November 2008, Pages: 3280–3294, Hideyo Ohuchi, Aska Hamada, Hironao Matsuda, Akira Takagi, Masayuki Tanaka, Junken Aoki, Hiroyuki Arai and Sumihare Noji

    Article first published online : 15 OCT 2008, DOI: 10.1002/dvdy.21736

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    TLR4 and S1P receptors cooperate to enhance inflammatory cytokine production in human gingival epithelial cells

    European Journal of Immunology

    Volume 38, Issue 4, April 2008, Pages: 1138–1147, Mehmet A. Eskan, Beate G. Rose, Manjunatha R. Benakanakere, Qun Zeng, Daisuke Fujioka, Michael H. Martin, Menq-Jer Lee and Denis F. Kinane

    Article first published online : 8 APR 2008, DOI: 10.1002/eji.200737898

  9. You have full text access to this OnlineOpen article
    Association of Sphingosine-1-phosphate (S1P)/S1P Receptor-1 Pathway with Cell Proliferation and Survival in Canine Hemangiosarcoma

    Journal of Veterinary Internal Medicine

    Volume 29, Issue 4, July/August 2015, Pages: 1088–1097, A.M. Rodriguez, A.J. Graef, D.N. LeVine, I.R. Cohen, J.F. Modiano and J.-H. Kim

    Article first published online : 25 JUN 2015, DOI: 10.1111/jvim.13570

  10. Sphingosine 1-phosphate receptor 1 and 3 are upregulated in multiple sclerosis lesions


    Volume 58, Issue 12, September 2010, Pages: 1465–1476, Ruben Van Doorn, Jack Van Horssen, Dennis Verzijl, Maarten Witte, Eric Ronken, Bert Van Het Hof, Kim Lakeman, Christine D. Dijkstra, Paul Van Der Valk, Arie Reijerkerk, Astrid E. Alewijnse, Stephan L. M. Peters and Helga E. De Vries

    Article first published online : 26 MAY 2010, DOI: 10.1002/glia.21021

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    Involvement of S1P1 receptor pathway in angiogenic effects of a novel adenosine-like nucleic acid analog COA-Cl in cultured human vascular endothelial cells

    Pharmacology Research & Perspectives

    Volume 2, Issue 5, October 2014, Junsuke Igarashi, Takeshi Hashimoto, Yasuo Kubota, Kazuyo Shoji, Tokumi Maruyama, Norikazu Sakakibara, Yoh Takuwa, Yoshihiro Ujihara, Yuki Katanosaka, Satoshi Mohri, Keiji Naruse, Tetsuo Yamashita, Ryuji Okamoto, Katsuya Hirano, Hiroaki Kosaka, Maki Takata, Ryoji Konishi and Ikuko Tsukamoto

    Article first published online : 6 AUG 2014, DOI: 10.1002/prp2.68

  12. Sphingosine-1-phosphate signaling in physiology and diseases


    Volume 38, Issue 5, September/October 2012, Pages: 329–337, Yoh Takuwa, Yasuo Okamoto, Kazuaki Yoshioka and Noriko Takuwa

    Article first published online : 7 JUN 2012, DOI: 10.1002/biof.1030

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    Embryonic brain expression analysis of lysophospholipid receptor genes suggests roles for s1p1 in neurogenesis and s1p1–3 in angiogenesis

    FEBS Letters

    Volume 531, Issue 1, October 30, 2002, Pages: 103–108, Christine McGiffert, James J.A Contos, Beth Friedman and Jerold Chun

    Article first published online : 21 SEP 2002, DOI: 10.1016/S0014-5793(02)03404-X

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    Sphingosine-1-phosphate and FTY720 as anti-atherosclerotic lipid compounds

    European Journal of Clinical Investigation

    Volume 37, Issue 3, March 2007, Pages: 171–179, M. Tölle, B. Levkau, B. Kleuser and M. Van Der Giet

    Article first published online : 26 FEB 2007, DOI: 10.1111/j.1365-2362.2007.01776.x

  15. Immunohistochemical detection of sphingosine-1-phosphate receptor 1 and 5 in human multiple sclerosis lesions

    Neuropathology and Applied Neurobiology

    Volume 40, Issue 5, August 2014, Pages: 564–578, Corinne Brana, Marie José Frossard, Rosanna Pescini Gobert, Nicolas Martinier, Ursula Boschert and Timothy J. Seabrook

    Article first published online : 1 JUL 2014, DOI: 10.1111/nan.12048

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    Identification of novel functional and spatial associations between sphingosine kinase 1, sphingosine 1-phosphate receptors and other signaling proteins that affect prognostic outcome in estrogen receptor-positive breast cancer

    International Journal of Cancer

    Volume 132, Issue 3, 1 February 2013, Pages: 605–616, Jan Ohotski, Joanne Edwards, Beatrix Elsberger, Carol Watson, Clare Orange, Elizabeth Mallon, Susan Pyne and Nigel J. Pyne

    Article first published online : 11 JUL 2012, DOI: 10.1002/ijc.27692

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    Platelet-derived growth factor (PDGF)-induced chemotaxis does not require the G protein-coupled receptor S1P1 in murine embryonic fibroblasts and vascular smooth muscle cells

    FEBS Letters

    Volume 533, Issue 1, January 02, 2003, Pages: 25–28, Michael J. Kluk, Chantal Colmont, Ming-Tao Wu and Timothy Hla

    Article first published online : 3 DEC 2002, DOI: 10.1016/S0014-5793(02)03742-0

  18. You have full text access to this OnlineOpen article
    The selective sphingosine 1-phosphate receptor modulator BAF312 redirects lymphocyte distribution and has species-specific effects on heart rate

    British Journal of Pharmacology

    Volume 167, Issue 5, November 2012, Pages: 1035–1047, P Gergely, B Nuesslein-Hildesheim, D Guerini, V Brinkmann, M Traebert, C Bruns, S Pan, NS Gray, K Hinterding, NG Cooke, A Groenewegen, A Vitaliti, T Sing, O Luttringer, J Yang, A Gardin, N Wang, WJ Crumb Jr, M Saltzman, M Rosenberg and E Wallström

    Article first published online : 8 OCT 2012, DOI: 10.1111/j.1476-5381.2012.02061.x

  19. Structural and functional characteristics of S1P receptors

    Journal of Cellular Biochemistry

    Volume 92, Issue 5, 1 August 2004, Pages: 913–922, Teresa Sanchez and Timothy Hla

    Article first published online : 26 MAY 2004, DOI: 10.1002/jcb.20127

  20. bFGF induces S1P1 receptor expression and functionality in human pulmonary artery smooth muscle cells

    Journal of Cellular Biochemistry

    Volume 105, Issue 4, 1 November 2008, Pages: 1139–1145, Magdalena Birker-Robaczewska, Rolf Studer, Bénédicte Haenig, Katalin Menyhart, Silke Hofmann and Oliver Nayler

    Article first published online : 4 SEP 2008, DOI: 10.1002/jcb.21918