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There are 19132 results for: content related to: Therapeutic implications of the MDR-1 gene

  1. Cloning and heterologous expression of the ovine (Ovis aries) P-glycoprotein (Mdr1) in Madin–Darby canine kidney (MDCK) cells

    Journal of Veterinary Pharmacology and Therapeutics

    Volume 33, Issue 3, June 2010, Pages: 304–311, D. ZAHNER, J. ALBER and E. PETZINGER

    Article first published online : 23 MAR 2010, DOI: 10.1111/j.1365-2885.2009.01141.x

  2. Selamectin is a potent substrate and inhibitor of human and canine P-glycoprotein

    Journal of Veterinary Pharmacology and Therapeutics

    Volume 28, Issue 3, June 2005, Pages: 257–265, J. GRIFFIN, N. FLETCHER, R. CLEMENCE, S. BLANCHFLOWER and D. J. BRAYDEN

    Article first published online : 9 OCT 2008, DOI: 10.1111/j.1365-2885.2005.00655.x

  3. P-glycoprotein in intestines, liver, kidney and lymphocytes in horse

    Journal of Veterinary Pharmacology and Therapeutics

    Volume 32, Issue 2, April 2009, Pages: 167–176, E. TYDÉN, J. TALLKVIST, H. TJÄLVE and P. LARSSON

    Article first published online : 7 OCT 2008, DOI: 10.1111/j.1365-2885.2008.01017.x

  4. Biliary excretion of technetium-99m-sestamibi in wild-type dogs and in dogs with intrinsic (ABCB1-1Δ mutation) and extrinsic (ketoconazole treated) P-glycoprotein deficiency

    Journal of Veterinary Pharmacology and Therapeutics

    Volume 32, Issue 5, October 2009, Pages: 417–421, J. C. COELHO, R. TUCKER, J. MATTOON, G. ROBERTS, D. K. WAITING and K. L. MEALEY

    Article first published online : 12 APR 2009, DOI: 10.1111/j.1365-2885.2009.01068.x

  5. Oral bioavailability of P-glycoprotein substrate drugs do not differ between ABCB1-1Δ and ABCB1 wild type dogs

    Journal of Veterinary Pharmacology and Therapeutics

    Volume 33, Issue 5, October 2010, Pages: 453–460, K. L. MEALEY, D. WAITING, D. L. RAUNIG, K. R. SCHMIDT and F. R. NELSON

    Article first published online : 19 APR 2010, DOI: 10.1111/j.1365-2885.2010.01170.x

  6. Pretreatment with the inducers rifampicin and phenobarbital alters ivermectin gastrointestinal disposition

    Journal of Veterinary Pharmacology and Therapeutics

    Volume 33, Issue 3, June 2010, Pages: 252–259, M. BALLENT, A. LIFSCHITZ, G. VIRKEL, L. MATE and C. LANUSSE

    Article first published online : 1 SEP 2009, DOI: 10.1111/j.1365-2885.2009.01129.x

  7. P-glycoprotein-mediated transport of oxytetracycline in the Caco-2 cell model

    Journal of Veterinary Pharmacology and Therapeutics

    Volume 30, Issue 1, February 2007, Pages: 25–31, J. SCHRICKX and J. FINK-GREMMELS

    Article first published online : 4 JAN 2007, DOI: 10.1111/j.1365-2885.2007.00808.x

  8. Involvement of P-glycoprotein on ivermectin kinetic behaviour in sheep: itraconazole-mediated changes on gastrointestinal disposition

    Journal of Veterinary Pharmacology and Therapeutics

    Volume 30, Issue 3, June 2007, Pages: 242–248, M. BALLENT, A. LIFSCHITZ, G. VIRKEL, J. SALLOVITZ and C. LANUSSE

    Article first published online : 13 APR 2007, DOI: 10.1111/j.1365-2885.2007.00848.x

  9. Fumagillin, a new P-glycoprotein-interfering agent able to modulate moxidectin efflux in rat hepatocytes

    Journal of Veterinary Pharmacology and Therapeutics

    Volume 29, Issue 6, December 2006, Pages: 489–494, J. DUPUY, A. LESPINE, J. F. SUTRA and M. ALVINERIE

    Article first published online : 2 NOV 2006, DOI: 10.1111/j.1365-2885.2006.00780.x

  10. The effect of P-Glycoprotein on methadone hydrochloride flux in equine intestinal mucosa

    Journal of Veterinary Pharmacology and Therapeutics

    Volume 36, Issue 1, February 2013, Pages: 43–50, R. L. LINARDI, A. M. STOKES and F. M. ANDREWS

    Article first published online : 19 MAR 2012, DOI: 10.1111/j.1365-2885.2012.01390.x

  11. Loperamide-induced enhancement of moxidectin availability in cattle

    Journal of Veterinary Pharmacology and Therapeutics

    Volume 25, Issue 2, April 2002, Pages: 111–120, A. LIFSCHITZ, G. VIRKEL, J. SALLOVITZ, F. IMPERIALE, A. PIS and C. LANUSSE

    Article first published online : 7 MAY 2002, DOI: 10.1046/j.1365-2885.2002.00396.x

  12. The pharmacogenomics of P-glycoprotein and its role in veterinary medicine

    Journal of Veterinary Pharmacology and Therapeutics

    Volume 31, Issue 4, August 2008, Pages: 285–300, M. MARTINEZ, S. MODRIC, M. SHARKEY, L. TROUTMAN, L. WALKER and K. MEALEY

    Article first published online : 16 MAY 2008, DOI: 10.1111/j.1365-2885.2008.00964.x

  13. A porcine lymphocyte model for P-gp inhibition studies

    Journal of Veterinary Pharmacology and Therapeutics

    Volume 34, Issue 5, October 2011, Pages: 499–501, J. A. SCHRICKX and J. FINK-GREMMELS

    Article first published online : 9 FEB 2011, DOI: 10.1111/j.1365-2885.2011.01270.x

  14. The effects of inhibiting cytochrome P450 3A, p-glycoprotein, and gastric acid secretion on the oral bioavailability of methadone in dogs

    Journal of Veterinary Pharmacology and Therapeutics

    Volume 28, Issue 5, October 2005, Pages: 461–466, B. KUKANICH, B. D. X. LASCELLES, A. M. AMAN, K. L. MEALEY and M. G. PAPICH

    Article first published online : 5 OCT 2005, DOI: 10.1111/j.1365-2885.2005.00681.x

  15. Pharmacological approaches towards rationalizing the use of endoparasitic drugs in small animals

    Journal of Veterinary Pharmacology and Therapeutics

    Volume 29, Issue 6, December 2006, Pages: 443–457, S. F. SANCHEZ BRUNI, D. G. JONES and Q. A. MCKELLAR

    Article first published online : 2 NOV 2006, DOI: 10.1111/j.1365-2885.2006.00806.x

  16. Cetirizine in horses: pharmacokinetics and effect of ivermectin pretreatment

    Journal of Veterinary Pharmacology and Therapeutics

    Volume 30, Issue 3, June 2007, Pages: 194–200, L. OLSÉN, C. INGVAST-LARSSON, U. BONDESSON, H. BROSTRÖM, H. TJÄLVE and P. LARSSON

    Article first published online : 18 APR 2007, DOI: 10.1111/j.1365-2885.2007.00850.x

  17. Moxidectin has a lower neurotoxic potential but comparable brain penetration in P-glycoprotein-deficient CF-1 mice compared to ivermectin

    Journal of Veterinary Pharmacology and Therapeutics

    Volume 36, Issue 3, June 2013, Pages: 275–284, C. JANKO and J. GEYER

    Article first published online : 27 JUL 2012, DOI: 10.1111/j.1365-2885.2012.01424.x

  18. The interaction between moxidectin and MDR transporters in primary cultures of rat hepatocytes

    Journal of Veterinary Pharmacology and Therapeutics

    Volume 29, Issue 2, April 2006, Pages: 107–111, J. DUPUY, A. LESPINE, J. F. SUTRA and M. ALVINERIE

    Article first published online : 1 MAR 2006, DOI: 10.1111/j.1365-2885.2006.00721.x

  19. Fexofenadine in horses: pharmacokinetics, pharmacodynamics and effect of ivermectin pretreatment

    Journal of Veterinary Pharmacology and Therapeutics

    Volume 29, Issue 2, April 2006, Pages: 129–135, L. OLSÉN, C. INGVAST-LARSSON, P. LARSSON, H. BROSTRÖM, U. BONDESSON, M. SUNDQVIST and H. TJÄLVE

    Article first published online : 1 MAR 2006, DOI: 10.1111/j.1365-2885.2006.00724.x

  20. D09 P-glycoprotein in the intestine, liver and kidney of the horse

    Journal of Veterinary Pharmacology and Therapeutics

    Volume 29, Issue s1, October 2006, Pages: 120–121, E. TYDÉN, H. TJÄLVE, J. TALLKVIST and P. LARSSON

    Article first published online : 30 AUG 2006, DOI: 10.1111/j.1365-2885.2006.00762_11.x