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There are 24090 results for: content related to: Therapeutic implications of the MDR-1 gene

  1. You have free access to this content
    Interactions between antidepressants and P-glycoprotein at the blood–brain barrier: clinical significance of in vitro and in vivo findings

    British Journal of Pharmacology

    Volume 165, Issue 2, January 2012, Pages: 289–312, Fionn E O'Brien, Timothy G Dinan, Brendan T Griffin and John F Cryan

    Version of Record online : 16 DEC 2011, DOI: 10.1111/j.1476-5381.2011.01557.x

  2. Differential involvement of P-glycoprotein (ABCB1) in permeability, tissue distribution, and antinociceptive activity of methadone, buprenorphine, and diprenorphine: In vitro and in vivo evaluation

    Journal of Pharmaceutical Sciences

    Volume 98, Issue 12, December 2009, Pages: 4928–4940, Hazem E. Hassan, Alan L. Myers, Andrew Coop and Natalie D. Eddington

    Version of Record online : 15 APR 2009, DOI: 10.1002/jps.21770

  3. You have free access to this content
    Selectivity in the impact of P-glycoprotein upon pulmonary absorption of airway-dosed substrates: A study in ex vivo lung models using chemical inhibition and genetic knockout

    Journal of Pharmaceutical Sciences

    Volume 102, Issue 9, September 2013, Pages: 3382–3394, Ghaith Al-Jayyoussi, Daniel F. Price, Danielle Francombe, Glyn Taylor, Mathew W. Smith, Chris Morris, Chris D. Edwards, Peter Eddershaw and Mark Gumbleton

    Version of Record online : 13 MAY 2013, DOI: 10.1002/jps.23587

  4. Oxycodone induces overexpression of P-glycoprotein (ABCB1) and affects paclitaxel's tissue distribution in Sprague Dawley rats

    Journal of Pharmaceutical Sciences

    Volume 96, Issue 9, September 2007, Pages: 2494–2506, Hazem E. Hassan, Alan L. Myers, Insong J. Lee, Andrew Coop and Natalie D. Eddington

    Version of Record online : 25 JUN 2007, DOI: 10.1002/jps.20893

  5. The pharmacogenomics of P-glycoprotein and its role in veterinary medicine

    Journal of Veterinary Pharmacology and Therapeutics

    Volume 31, Issue 4, August 2008, Pages: 285–300, M. MARTINEZ, S. MODRIC, M. SHARKEY, L. TROUTMAN, L. WALKER and K. MEALEY

    Version of Record online : 16 MAY 2008, DOI: 10.1111/j.1365-2885.2008.00964.x

  6. Radiopharmaceuticals for assessing ABC transporters at the blood–brain barrier

    Clinical Pharmacology & Therapeutics

    Volume 97, Issue 4, April 2015, Pages: 362–371, RM Raaphorst, AD Windhorst, PH Elsinga, NA Colabufo, AA Lammertsma and G Luurtsema

    Version of Record online : 11 FEB 2015, DOI: 10.1002/cpt.73

  7. Why Clinical Modulation of Efflux Transport at the Human Blood–Brain Barrier Is Unlikely: The ITC Evidence-Based Position

    Clinical Pharmacology & Therapeutics

    Volume 94, Issue 1, July 2013, Pages: 80–94, J C Kalvass, J W Polli, D L Bourdet, B Feng, S-M Huang, X Liu, Q R Smith, L K Zhang, M J Zamek-Gliszczynski and International Transporter Consortium

    Version of Record online : 14 FEB 2013, DOI: 10.1038/clpt.2013.34

  8. Suitability of digoxin as a P-glycoprotein probe: Implications of other transporters on sensitivity and specificity

    The Journal of Clinical Pharmacology

    Volume 54, Issue 1, January 2014, Pages: 3–13, Ahmed M. Nader and David R. Foster

    Version of Record online : 26 OCT 2013, DOI: 10.1002/jcph.200

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    P-glycoprotein in blood–brain barrier endothelial cells: interaction and oligomerization with caveolins

    Journal of Neurochemistry

    Volume 87, Issue 4, November 2003, Pages: 1010–1023, Julie Jodoin, Michel Demeule, Laurence Fenart, Roméo Cecchelli, Sarah Farmer, Kenneth J. Linton, Christopher F. Higgins and Richard Béliveau

    Version of Record online : 4 FEB 2004, DOI: 10.1046/j.1471-4159.2003.02081.x

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    Induction of P-glycoprotein and Bcrp at the rat blood–brain barrier following a subchronic morphine treatment is mediated through NMDA/COX-2 activation

    Journal of Neurochemistry

    Volume 123, Issue 4, November 2012, Pages: 491–503, Salah Yousif, Catarina Chaves, Sophie Potin, Isabelle Margaill, Jean-Michel Scherrmann and Xavier Declèves

    Version of Record online : 3 SEP 2012, DOI: 10.1111/j.1471-4159.2012.07890.x

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    Effect of P-glycoprotein expression levels on the concentration-dependent permeability of drugs to the cell membrane

    Journal of Pharmaceutical Sciences

    Volume 97, Issue 1, January 2008, Pages: 553–565, Yoshiyuki Shirasaka, Toshiyasu Sakane and Shinji Yamashita

    Version of Record online : 7 SEP 2007, DOI: 10.1002/jps.21114

  12. Imaging the Function of P-Glycoprotein With Radiotracers: Pharmacokinetics and In Vivo Applications

    Clinical Pharmacology & Therapeutics

    Volume 86, Issue 4, October 2009, Pages: 368–377, P Kannan, C John, S S Zoghbi, C Halldin, M M Gottesman, R B Innis and M D Hall

    Version of Record online : 22 JUL 2009, DOI: 10.1038/clpt.2009.138

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    Hepatobiliary and intestinal clearance of amphiphilic cationic drugs in mice in which both mdr1a and mdr1b genes have been disrupted

    British Journal of Pharmacology

    Volume 124, Issue 2, May 1998, Pages: 416–424, Johan W Smit, Alfred H Schinkel, Betty Weert and Dirk K F Meijer

    Version of Record online : 3 FEB 2009, DOI: 10.1038/sj.bjp.0701845

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    Minocycline and riluzole brain disposition: interactions with p-glycoprotein at the blood–brain barrier

    Journal of Neurochemistry

    Volume 103, Issue 1, October 2007, Pages: 164–173, Aline Milane, Christine Fernandez, Sarah Vautier, Gilbert Bensimon, Vincent Meininger and Robert Farinotti

    Version of Record online : 18 JUN 2007, DOI: 10.1111/j.1471-4159.2007.04772.x


    Clinical and Experimental Pharmacology and Physiology

    Volume 34, Issue 4, April 2007, Pages: 296–303, Stanislav Micuda, Leos Fuksa, Lucie Mundlova, Jan Osterreicher, Jaroslav Mokry, Jolana Cermanova, Eva Brcakova, Frantisek Staud, Pavla Pokorna and Jirina Martinkova

    Version of Record online : 23 FEB 2007, DOI: 10.1111/j.1440-1681.2007.04558.x

  16. Establishment of a cell line for assessing drugs as canine P-glycoprotein substrates: proof of principle

    Journal of Veterinary Pharmacology and Therapeutics

    Volume 40, Issue 5, October 2017, Pages: 545–551, K. L. Mealey, S. Dassanayake and N. S. Burke

    Version of Record online : 17 JAN 2017, DOI: 10.1111/jvp.12390

  17. The impact of pharmacologic and genetic knockout of P-glycoprotein on nelfinavir levels in the brain and other tissues in mice

    Journal of Pharmaceutical Sciences

    Volume 94, Issue 6, June 2005, Pages: 1216–1225, Noha N. Salama, Edward J. Kelly, Tot Bui and Rodney J.Y. Ho

    Version of Record online : 27 APR 2005, DOI: 10.1002/jps.20344

  18. You have free access to this content
    HIV-Tat protein induces P-glycoprotein expression in brain microvascular endothelial cells

    Journal of Neurochemistry

    Volume 93, Issue 5, June 2005, Pages: 1231–1241, Kentaro Hayashi, Hong Pu, Jing Tian, Ibolya E. Andras, Yong Woo Lee, Bernhard Hennig and Michal Toborek

    Version of Record online : 4 APR 2005, DOI: 10.1111/j.1471-4159.2005.03114.x

  19. PET Radiotracers for Imaging P-glycoprotein: The Challenge for Early Diagnosis in AD


    Volume 9, Issue 1, January 2014, Pages: 38–42, Prof. Marcello Leopoldo, Dr. Marialessandra Contino, Prof. Francesco Berardi, Prof. Roberto Perrone and Prof. Nicola Antonio Colabufo

    Version of Record online : 31 OCT 2013, DOI: 10.1002/cmdc.201300362

  20. You have full text access to this Open Access content
    P-Glycoprotein Mediated Drug Interactions in Animals and Humans with Cancer

    Journal of Veterinary Internal Medicine

    Volume 29, Issue 1, January/February 2015, Pages: 1–6, K.L. Mealey and J. Fidel

    Version of Record online : 25 JAN 2015, DOI: 10.1111/jvim.12525