Search Results

There are 11457 results for: content related to: The pharmacogenomics of P-glycoprotein and its role in veterinary medicine

  1. MDR1 haplotypes significantly minimize intracellular uptake and transcellular P-gp substrate transport in recombinant LLC-PK1 cells

    Journal of Pharmaceutical Sciences

    Volume 95, Issue 10, October 2006, Pages: 2293–2308, Noha N. Salama, Ziping Yang, Tot Bui and Rodney J.Y. Ho

    Version of Record online : 1 AUG 2006, DOI: 10.1002/jps.20717

  2. Differential susceptibility of P-glycoprotein deficient mice to colitis induction by environmental insults

    Inflammatory Bowel Diseases

    Volume 15, Issue 5, May 2009, Pages: 684–696, Elizabeth M. Staley, Trenton R. Schoeb and Robin G. Lorenz

    Version of Record online : 9 DEC 2008, DOI: 10.1002/ibd.20824

  3. The impact of pharmacologic and genetic knockout of P-glycoprotein on nelfinavir levels in the brain and other tissues in mice

    Journal of Pharmaceutical Sciences

    Volume 94, Issue 6, June 2005, Pages: 1216–1225, Noha N. Salama, Edward J. Kelly, Tot Bui and Rodney J.Y. Ho

    Version of Record online : 27 APR 2005, DOI: 10.1002/jps.20344

  4. You have free access to this content
    Selectivity in the impact of P-glycoprotein upon pulmonary absorption of airway-dosed substrates: A study in ex vivo lung models using chemical inhibition and genetic knockout

    Journal of Pharmaceutical Sciences

    Volume 102, Issue 9, September 2013, Pages: 3382–3394, Ghaith Al-Jayyoussi, Daniel F. Price, Danielle Francombe, Glyn Taylor, Mathew W. Smith, Chris Morris, Chris D. Edwards, Peter Eddershaw and Mark Gumbleton

    Version of Record online : 13 MAY 2013, DOI: 10.1002/jps.23587

  5. Differential involvement of P-glycoprotein (ABCB1) in permeability, tissue distribution, and antinociceptive activity of methadone, buprenorphine, and diprenorphine: In vitro and in vivo evaluation

    Journal of Pharmaceutical Sciences

    Volume 98, Issue 12, December 2009, Pages: 4928–4940, Hazem E. Hassan, Alan L. Myers, Andrew Coop and Natalie D. Eddington

    Version of Record online : 15 APR 2009, DOI: 10.1002/jps.21770

  6. You have free access to this content
    Downregulation of mdr1a expression in the brain and liver during CNS inflammation alters the in vivo disposition of digoxin

    British Journal of Pharmacology

    Volume 139, Issue 1, May 2003, Pages: 35–48, Kerry B Goralski, Georgy Hartmann, Micheline Piquette-Miller and Kenneth W Renton

    Version of Record online : 29 JAN 2009, DOI: 10.1038/sj.bjp.0705227

  7. MORPHOLOGICAL AND FUNCTIONAL CHANGES IN P-GLYCOPROTEIN DURING DEXAMETHASONE-INDUCED HEPATOMEGALY

    Clinical and Experimental Pharmacology and Physiology

    Volume 34, Issue 4, April 2007, Pages: 296–303, Stanislav Micuda, Leos Fuksa, Lucie Mundlova, Jan Osterreicher, Jaroslav Mokry, Jolana Cermanova, Eva Brcakova, Frantisek Staud, Pavla Pokorna and Jirina Martinkova

    Version of Record online : 23 FEB 2007, DOI: 10.1111/j.1440-1681.2007.04558.x

  8. Polymorphisms in Human MDR1 (P-glycoprotein): Recent Advances and Clinical Relevance

    Clinical Pharmacology & Therapeutics

    Volume 75, Issue 1, January 2004, Pages: 13–33, Catia Marzolini, Erik Paus, Thierry Buclin and Richard B. Kim

    Version of Record online : 22 JAN 2004, DOI: 10.1016/j.clpt.2003.09.012

  9. You have free access to this content
    Determining MDR1/P-glycoprotein expression in breast cancer

    International Journal of Cancer

    Volume 93, Issue 1, 1 July 2001, Pages: 114–122, Ian F. Faneyte, Petra M.P. Kristel and Marc J. van de Vijver

    Version of Record online : 30 MAY 2001, DOI: 10.1002/1097-0215(20010701)93:1<114::AID-IJC1309>3.0.CO;2-J

  10. Oxycodone induces overexpression of P-glycoprotein (ABCB1) and affects paclitaxel's tissue distribution in Sprague Dawley rats

    Journal of Pharmaceutical Sciences

    Volume 96, Issue 9, September 2007, Pages: 2494–2506, Hazem E. Hassan, Alan L. Myers, Insong J. Lee, Andrew Coop and Natalie D. Eddington

    Version of Record online : 25 JUN 2007, DOI: 10.1002/jps.20893

  11. A comparison of commonly used polyethoxylated pharmaceutical excipients on their ability to inhibit P-glycoprotein activity in vitro

    Journal of Pharmaceutical Sciences

    Volume 91, Issue 9, September 2002, Pages: 1991–2002, Erin D. Hugger, Barbara L. Novak, Philip S. Burton, Kenneth L. Audus and Ronald T. Borchardt

    Version of Record online : 14 JUN 2002, DOI: 10.1002/jps.10176

  12. Species differences of inhibitory effects on P-glycoprotein-mediated drug transport

    Journal of Pharmaceutical Sciences

    Volume 96, Issue 6, June 2007, Pages: 1609–1618, Naoto Suzuyama, Miki Katoh, Toshiyuki Takeuchi, Sumie Yoshitomi, Tomoaki Higuchi, Satoru Asashi and Tsuyoshi Yokoi

    Version of Record online : 8 NOV 2006, DOI: 10.1002/jps.20787

  13. High Levels of P-Glycoprotein Activity in Human Lymphocytes in the First 6 Months of Life

    Clinical Pharmacology & Therapeutics

    Volume 85, Issue 3, March 2009, Pages: 289–295, C Giraud, X Declèves, JY Perrot, S Manceau, E Pannier, G Firtion, JP Morini, H Chappuy, F Batteux, S Chouzenoux, JM Scherrmann, S Blanche and JM Tréluyer

    Version of Record online : 26 NOV 2008, DOI: 10.1038/clpt.2008.221

  14. You have free access to this content
    Effect of chronic exposure to morphine on the rat blood–brain barrier: focus on the P-glycoprotein

    Journal of Neurochemistry

    Volume 107, Issue 3, November 2008, Pages: 647–657, Salah Yousif, Bruno Saubaméa, Salvatore Cisternino, Cynthia Marie-Claire, Sandrine Dauchy, Jean-Michel Scherrmann and Xavier Declèves

    Version of Record online : 29 AUG 2008, DOI: 10.1111/j.1471-4159.2008.05647.x

  15. You have free access to this content
    Induction of P-glycoprotein and Bcrp at the rat blood–brain barrier following a subchronic morphine treatment is mediated through NMDA/COX-2 activation

    Journal of Neurochemistry

    Volume 123, Issue 4, November 2012, Pages: 491–503, Salah Yousif, Catarina Chaves, Sophie Potin, Isabelle Margaill, Jean-Michel Scherrmann and Xavier Declèves

    Version of Record online : 3 SEP 2012, DOI: 10.1111/j.1471-4159.2012.07890.x

  16. Patterns of P-glycoprotein activity in the nervous system during vincristine-induced neuropathy in rats

    Journal of the Peripheral Nervous System

    Volume 10, Issue 3, September 2005, Pages: 301–310, David Balayssac, Anne Cayre, Nicolas Authier, Sophie Bourdu, Frederique Penault-Llorca, Jean Pierre Gillet, Jean Maublant, Alain Eschalier and François Coudore

    Version of Record online : 7 OCT 2005, DOI: 10.1111/j.1085-9489.2005.10308.x

  17. You have free access to this content
    Role of blood-brain barrier P-glycoprotein in limiting brain accumulation and sedative side-effects of asimadoline, a peripherally acting analgaesic drug

    British Journal of Pharmacology

    Volume 127, Issue 1, May 1999, Pages: 43–50, J W Jonker, E Wagenaar, L Van Deemter, R Gottschlich, H M Bender, J Dasenbrock and A H Schinkel

    Version of Record online : 29 JAN 2009, DOI: 10.1038/sj.bjp.0702497

  18. You have free access to this content
    Potential Role of Drug Transporters in the Pathogenesis of Medically Intractable Epilepsy

    Epilepsia

    Volume 46, Issue 2, February 2005, Pages: 224–235, Patrick Kwan and Martin J. Brodie

    Version of Record online : 24 JAN 2005, DOI: 10.1111/j.0013-9580.2005.31904.x

  19. Kinetic analyses for species differences in P-glycoprotein-mediated drug transport

    Journal of Pharmaceutical Sciences

    Volume 95, Issue 12, December 2006, Pages: 2673–2683, Miki Katoh, Naoto Suzuyama, Toshiyuki Takeuchi, Sumie Yoshitomi, Satoru Asahi and Tsuyoshi Yokoi

    Version of Record online : 4 AUG 2006, DOI: 10.1002/jps.20686

  20. A comprehensive study demonstrating that p-glycoprotein function is directly affected by changes in pH: Implications for intestinal pH and effects on drug absorption

    Journal of Pharmaceutical Sciences

    Volume 100, Issue 10, October 2011, Pages: 4258–4268, Pallabi Mitra, Kenneth Audus, Gervan Williams, Mehran Yazdanian and Deborah Galinis

    Version of Record online : 27 APR 2011, DOI: 10.1002/jps.22596