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There are 1118 results for: content related to: Effect of dexmedetomidine on its clearance: a pharmacokinetic model

  1. You have free access to this content
    Alpha-2 agonists for long-term sedation during mechanical ventilation in critically ill patients

    Intervention Review

    The Cochrane Library

    Ken Chen, Zhijun Lu, Yi Chun Xin, Yong Cai, Yi Chen and Shu Ming Pan

    Published Online : 6 JAN 2015, DOI: 10.1002/14651858.CD010269.pub2

  2. A Case-Based Approach to the Practical Application of Dexmedetomidine in Critically Ill Adults

    Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy

    Volume 33, Issue 2, February 2013, Pages: 165–186, Robert MacLaren, Jill C. Krisl, Rebecca E. Cochrane and Scott W. Mueller

    Article first published online : 5 FEB 2013, DOI: 10.1002/phar.1175

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    Signalling pathways for transactivation by dexmedetomidine of epidermal growth factor receptors in astrocytes and its paracrine effect on neurons

    British Journal of Pharmacology

    Volume 154, Issue 1, May 2008, Pages: 191–203, B Li, T Du, H Li, L Gu, H Zhang, J Huang, L Hertz and L Peng

    Article first published online : 29 JAN 2009, DOI: 10.1038/bjp.2008.58

  4. Effect of dexmedetomidine on propofol requirements in healthy subjects

    Journal of Pharmaceutical Sciences

    Volume 90, Issue 2, February 2001, Pages: 172–181, Sandeep Dutta, Michael D. Karol, Theodora Cohen, Ron M. Jones and Timothy Mant

    Article first published online : 10 JAN 2001, DOI: 10.1002/1520-6017(200102)90:2<172::AID-JPS8>3.0.CO;2-J

  5. You have full text access to this OnlineOpen article
    Action of dexmedetomidine on the substantia gelatinosa neurons of the rat spinal cord

    European Journal of Neuroscience

    Volume 27, Issue 12, June 2008, Pages: 3182–3190, Hideaki Ishii, Tatsuro Kohno, Tomohiro Yamakura, Miho Ikoma and Hiroshi Baba

    Article first published online : 28 JUN 2008, DOI: 10.1111/j.1460-9568.2008.06260.x

  6. Hemodynamic effects of dexmedetomidine in isoflurane-anesthetized cats

    Veterinary Anaesthesia and Analgesia

    Volume 38, Issue 6, November 2011, Pages: 555–567, Bruno H Pypendop, Linda S Barter, Scott D Stanley and Jan E Ilkiw

    Article first published online : 12 OCT 2011, DOI: 10.1111/j.1467-2995.2011.00663.x

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    High concentrations of dexmedetomidine inhibit compound action potentials in frog sciatic nerves without α2 adrenoceptor activation

    British Journal of Pharmacology

    Volume 160, Issue 7, August 2010, Pages: 1662–1676, Toshifumi Kosugi, Kotaro Mizuta, Tsugumi Fujita, Mikio Nakashima and Eiichi Kumamoto

    Article first published online : 3 MAY 2010, DOI: 10.1111/j.1476-5381.2010.00833.x

  8. Dexmedetomidine-induced contraction involves c-Jun NH2-terminal kinase phosphorylation through activation of the 5-lipoxygenase pathway in the isolated endothelium-denuded rat aorta

    Clinical and Experimental Pharmacology and Physiology

    Volume 41, Issue 12, December 2014, Pages: 1014–1022, Seong-Ho Ok, Hyo-Jin Byon, Hana Jin, Hye Jung Kim, Woochan Kim, In-Koo Nam, So Young Eun and Ju-Tae Sohn

    Article first published online : 2 DEC 2014, DOI: 10.1111/1440-1681.12307

  9. Dexmedetomidine: perioperative applications in children

    Pediatric Anesthesia

    Volume 20, Issue 3, March 2010, Pages: 256–264, VIVIAN MAN YING YUEN

    Article first published online : 10 DEC 2009, DOI: 10.1111/j.1460-9592.2009.03207.x

  10. Efficacy and safety of intraoperative dexmedetomidine for acute postoperative pain in children: a meta-analysis of randomized controlled trials

    Pediatric Anesthesia

    Volume 23, Issue 2, February 2013, Pages: 170–179, Alexander Schnabel, Sylvia U. Reichl, Daniel M. Poepping, Peter Kranke, Esther M. Pogatzki-Zahn and Peter K. Zahn

    Article first published online : 9 OCT 2012, DOI: 10.1111/pan.12030

  11. Dexmedetomidine as an Adjuvant to Analgesic Strategy During Vaso-Occlusive Episodes in Adolescents with Sickle-Cell Disease

    Pain Practice

    Volume 15, Issue 8, November 2015, Pages: E90–E97, Kathy A. Sheehy, Julia C. Finkel, Deepika S. Darbari, Michael F. Guerrera and Zenaide M. N. Quezado

    Article first published online : 23 JUL 2015, DOI: 10.1111/papr.12336

  12. Dexmedetomidine And Haemodynamic Responses To Acute Central Hypovolaemia In Conscious Rabbits

    Clinical and Experimental Pharmacology and Physiology

    Volume 27, Issue 10, October 2000, Pages: 801–809, Dw Blake, J Ludbrook and Af Van Leeuwen

    Article first published online : 24 DEC 2001, DOI: 10.1046/j.1440-1681.2000.03345.x

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    Dexmedetomidine for the management of awake fibreoptic intubation

    Intervention Review

    The Cochrane Library

    Xing-Ying He, Jian-Ping Cao, Qian He and Xue-Yin Shi

    Published Online : 19 JAN 2014, DOI: 10.1002/14651858.CD009798.pub2

  14. Pharmacokinetics and pharmacodynamics of intravenous dexmedetomidine in the horse

    Journal of Veterinary Pharmacology and Therapeutics

    Volume 38, Issue 1, February 2015, Pages: 15–23, M. L. Rezende, K. N. Grimsrud, S. D. Stanley, E. P. Steffey and K. R. Mama

    Article first published online : 27 JUL 2014, DOI: 10.1111/jvp.12138

  15. The effects of ketamine on dexmedetomidine-induced electrophysiologic changes in children

    Pediatric Anesthesia

    Volume 23, Issue 10, October 2013, Pages: 898–905, Danton Char, David R. Drover, Kara S. Motonaga, Sanjiv Gupta, Christina Y. Miyake, Anne M. Dubin and Gregory B. Hammer

    Article first published online : 18 MAR 2013, DOI: 10.1111/pan.12143

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    Dexmedetomidine and ST-91 analgesia in the formalin model is mediated by α2A-adrenoceptors: a mechanism of action distinct from morphine

    British Journal of Pharmacology

    Volume 155, Issue 7, December 2008, Pages: 1117–1126, A Nazarian, C A Christianson, X-Y Hua and T L Yaksh

    Article first published online : 29 JAN 2009, DOI: 10.1038/bjp.2008.341

  17. DIRECT EFFECT OF DEXMEDETOMIDINE ON RAT ISOLATED AORTA INVOLVES ENDOTHELIAL NITRIC OXIDE SYNTHESIS AND ACTIVATION OF THE LIPOXYGENASE PATHWAY

    Clinical and Experimental Pharmacology and Physiology

    Volume 36, Issue 4, April 2009, Pages: 406–412, Hee-Jin Kim, Ju-Tae Sohn, Young-Seok Jeong, Man Seok Cho, Hye Jung Kim, Ki Churl Chang, Mi-Kyung Shin, Chang-Shin Park and Young-Kyun Chung

    Article first published online : 6 NOV 2008, DOI: 10.1111/j.1440-1681.2008.05082.x

  18. Effects of dexmedetomidine on cardiorespiratory regulation in spontaneously breathing newborn rats

    Pediatric Anesthesia

    Volume 24, Issue 12, December 2014, Pages: 1245–1251, Junko Tamiya, Ryoji Ide, Masayuki Takahashi and Chikako Saiki

    Article first published online : 12 SEP 2014, DOI: 10.1111/pan.12530

  19. You have full text access to this OnlineOpen article
    Staying awake – a genetic region that hinders α2 adrenergic receptor agonist-induced sleep

    European Journal of Neuroscience

    Volume 40, Issue 1, July 2014, Pages: 2311–2319, Cigdem Gelegen, Thomas C. Gent, Valentina Ferretti, Zhe Zhang, Raquel Yustos, Fei Lan, Qianzi Yang, Dorothy W. U. Overington, Alexei L. Vyssotski, Hein A. van Lith, William Wisden and Nicholas P. Franks

    Article first published online : 27 MAR 2014, DOI: 10.1111/ejn.12570

  20. Integrative Review Utilizing Dexmedetomidine as an Anesthetic for Monitored Anesthesia Care and Regional Anesthesia

    Nursing Forum

    Volume 46, Issue 3, July-September 2011, Pages: 186–194, Michelle B. Drown

    Article first published online : 2 AUG 2011, DOI: 10.1111/j.1744-6198.2011.00229.x