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There are 7432 results for: content related to: Genetic variants associated with cisplatin-induced hearing loss

  1. Replication of TPMT and ABCC3 Genetic Variants Highly Associated With Cisplatin-Induced Hearing Loss in Children

    Clinical Pharmacology & Therapeutics

    Volume 94, Issue 2, August 2013, Pages: 243–251, K Pussegoda, C J Ross, H Visscher, M Yazdanpanah, B Brooks, S R Rassekh, Y F Zada, M-P Dubé, B C Carleton, M R Hayden and CPNDS Consortium

    Version of Record online : 10 APR 2013, DOI: 10.1038/clpt.2013.80

  2. The Role of Inherited TPMT and COMT Genetic Variation in Cisplatin-Induced Ototoxicity in Children With Cancer

    Clinical Pharmacology & Therapeutics

    Volume 94, Issue 2, August 2013, Pages: 252–259, J J Yang, J Y S Lim, J Huang, J Bass, J Wu, C Wang, J Fang, E Stewart, E H Harstead, S E, G W Robinson, W E Evans, A Pappo, J Zuo, M V Relling, A Onar-Thomas, A Gajjar and C F Stewart

    Version of Record online : 11 JUN 2013, DOI: 10.1038/clpt.2013.121

  3. You have full text access to this OnlineOpen article
    Thiopurine methyltransferase and treatment outcome in the UK acute lymphoblastic leukaemia trial ALL2003

    British Journal of Haematology

    Volume 170, Issue 4, August 2015, Pages: 550–558, Lynne Lennard, Cher S. Cartwright, Rachel Wade and Ajay Vora

    Version of Record online : 5 MAY 2015, DOI: 10.1111/bjh.13469

  4. You have free access to this content
    Pharmacogenomics – how close/far are we to practising individualized medicine for children?

    British Journal of Clinical Pharmacology

    Volume 79, Issue 3, March 2015, Pages: 419–428, Chor-Wing Sing, Ching-Lung Cheung and Ian C. K. Wong

    Version of Record online : 20 FEB 2015, DOI: 10.1111/bcp.12338

  5. You have free access to this content
    Thiopurine methyltransferase genotype–phenotype discordance and thiopurine active metabolite formation in childhood acute lymphoblastic leukaemia

    British Journal of Clinical Pharmacology

    Volume 76, Issue 1, July 2013, Pages: 125–136, Lynne Lennard, Cher Suzanne Cartwright, Rachel Wade, Susan M. Richards and Ajay Vora

    Version of Record online : 20 JUN 2013, DOI: 10.1111/bcp.12066

  6. You have full text access to this OnlineOpen article
    Thiopurine dose intensity and treatment outcome in childhood lymphoblastic leukaemia: the influence of thiopurine methyltransferase pharmacogenetics

    British Journal of Haematology

    Volume 169, Issue 2, April 2015, Pages: 228–240, Lynne Lennard, Cher S. Cartwright, Rachel Wade and Ajay Vora

    Version of Record online : 29 NOV 2014, DOI: 10.1111/bjh.13240

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    Polymorphic Variation in TPMT Is the Principal Determinant of TPMT Phenotype: A Meta-Analysis of Three Genome-Wide Association Studies

    Clinical Pharmacology & Therapeutics

    Volume 101, Issue 5, May 2017, Pages: 684–695, R Tamm, R Mägi, R Tremmel, S Winter, E Mihailov, A Smid, A Möricke, K Klein, M Schrappe, M Stanulla, R Houlston, R Weinshilboum, Irena Mlinarič Raščan, A Metspalu, L Milani, M Schwab and E Schaeffeler

    Version of Record online : 1 FEB 2017, DOI: 10.1002/cpt.540

  8. Genomewide Approach Validates Thiopurine Methyltransferase Activity Is a Monogenic Pharmacogenomic Trait

    Clinical Pharmacology & Therapeutics

    Volume 101, Issue 3, March 2017, Pages: 373–381, C Liu, W Yang, D Pei, C Cheng, C Smith, W Landier, L Hageman, Y Chen, JJ Yang, KR Crews, N Kornegay, SE Karol, FL Wong, S Jeha, JT Sandlund, RC Ribeiro, JE Rubnitz, ML Metzger, C-H Pui, WE Evans, S Bhatia and MV Relling

    Version of Record online : 18 NOV 2016, DOI: 10.1002/cpt.463

  9. Genetic Polymorphism of Inosine Triphosphate Pyrophosphatase Is a Determinant of Mercaptopurine Metabolism and Toxicity During Treatment for Acute Lymphoblastic Leukemia

    Clinical Pharmacology & Therapeutics

    Volume 85, Issue 2, February 2009, Pages: 164–172, G Stocco, MH Cheok, KR Crews, T Dervieux, D French, D Pei, W Yang, C Cheng, C-H Pui, MV Relling and WE Evans

    Version of Record online : 6 AUG 2008, DOI: 10.1038/clpt.2008.154

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    Implementation of TPMT testing

    British Journal of Clinical Pharmacology

    Volume 77, Issue 4, April 2014, Pages: 704–714, Lynne Lennard

    Version of Record online : 20 MAR 2014, DOI: 10.1111/bcp.12226

  11. Role of TPMT and COMT genetic variation in cisplatin-induced ototoxicity

    Clinical Pharmacology & Therapeutics

    Volume 95, Issue 3, March 2014, Page: 253, B C Carleton, C J Ross, A P Bhavsar, U Amstutz, K Pussegoda, H Visscher, J W Lee, B Brooks, S R Rassekh, M-P Dubé and M R Hayden

    Version of Record online : 5 NOV 2013, DOI: 10.1038/clpt.2013.219

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    Tracing the Origin of the Most Common Thiopurine Methyltransferase (TPMT) Variants: Preliminary Data from the Patterns of Haplotypic Association with Two CA Repeats

    Annals of Human Genetics

    Volume 68, Issue 4, July 2004, Pages: 313–323, S. Alves, J. Rocha, A. Amorim and M. J. Prata

    Version of Record online : 28 JUN 2004, DOI: 10.1046/j.1529-8817.2004.00104.x

  13. Genetic Markers of Cisplatin-Induced Hearing Loss in Children

    Clinical Pharmacology & Therapeutics

    Volume 96, Issue 3, September 2014, Pages: 296–298, B C Carleton, C J Ross, K Pussegoda, A P Bhavsar, H Visscher, J W Lee, B Brooks, S R Rassekh, M-P P Dubé and M R Hayden

    Version of Record online : 22 APR 2014, DOI: 10.1038/clpt.2014.92

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    Phenotyping and genotyping study of thiopurine S-methyltransferase in healthy Chinese children: A comparison of Han and Yao ethnic groups

    British Journal of Clinical Pharmacology

    Volume 58, Issue 2, August 2004, Pages: 163–168, Jian-ping Zhang, Yong-yuan Guan, Jue-heng Wu, An-Long Xu, Shufeng Zhou and Min Huang

    Version of Record online : 4 JUN 2004, DOI: 10.1111/j.1365-2125.2004.02113.x

  15. TPMT genetic variations in populations of the Russian Federation

    Pediatric Blood & Cancer

    Volume 52, Issue 2, February 2009, Pages: 203–208, Elena V. Samochatova, Natalia V. Chupova, Anastassia Rudneva, Olga Makarova, Tatyana V. Nasedkina, Olga E. Fedorova, Andrei S. Glotov, Zh. Kozhekbaeva, Olga A. Maiorova, Alexander G. Roumyantsev, Eugene Y. Krynetski, Natalia F. Krynetskaia, William E. Evans and Raul C. Ribeiro

    Version of Record online : 25 NOV 2008, DOI: 10.1002/pbc.21837

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    Genotypic and phenotypic analysis of the polymorphic thiopurine S-methyltransferase gene (TPMT) in a European population

    British Journal of Pharmacology

    Volume 125, Issue 4, October 1998, Pages: 879–887, Catherine Spire-Vayron de la Moureyre, Hervé Debuysere, Bruno Mastain, Elizabeth Vinner, Delphine Marez, Jean-Marc Lo Guidice, Dany Chevalier, Serge Brique, Kokou Motte, Jean-Frédéric Colombel, Dominique Turck, Christian Noel, René-Marc Flipo, Annie Pol, Michel Lhermitte, Jean-Jacques Lafitte, Christian Libersa and Franck Broly

    Version of Record online : 3 FEB 2009, DOI: 10.1038/sj.bjp.0702152

  17. Association of genetic variability in enzymes metabolizing chemotherapeutic agents with treatment response in head and neck cancer cases

    Asia-Pacific Journal of Clinical Oncology

    Volume 13, Issue 2, April 2017, Pages: e11–e20, Ankur Dhawan, Munindra Ruwali, Mohan C Pant, Qamar Rahman and Devendra Parmar

    Version of Record online : 21 JAN 2016, DOI: 10.1111/ajco.12446

  18. A New Thiopurine S-Methyltransferase Haplotype Associated With Intolerance to Azathioprine

    The Journal of Clinical Pharmacology

    Volume 53, Issue 1, January 2013, Pages: 67–74, Lara Colleoni, Dimos Kapetis, Lorenzo Maggi, Giorgia Camera, Eleonora Canioni, Paola Cavalcante, Nicole Kerlero de Rosbo, Fulvio Baggi, Carlo Antozzi, Paolo Confalonieri, Renato Mantegazza and Pia Bernasconi

    Version of Record online : 24 JAN 2013, DOI: 10.1177/0091270011435989

  19. Response to “Evaluation of Pharmacogenetic Markers to Predict the Risk of Cisplatin-Induced Ototoxicity”

    Clinical Pharmacology & Therapeutics

    Volume 96, Issue 2, August 2014, Page: 158, B C Carleton, C J Ross, A P Bhavsar, J W Lee, H Visscher, S R Rassekh and M R Hayden

    Version of Record online : 22 APR 2014, DOI: 10.1038/clpt.2014.90

  20. Pharmacogenetically based dosing of thiopurines in childhood acute lymphoblastic leukemia: Influence on cure rates and risk of second cancer

    Pediatric Blood & Cancer

    Volume 61, Issue 5, May 2014, Pages: 797–802, Mette Levinsen, Elisabeth Ørskov Rotevatn, Susanne Rosthøj, Jacob Nersting, Jonas Abrahamsson, Malin Lindqvist Appell, Stein Bergan, Anne-Grete Bechensteen, Arja Harila-Saari, Mats Heyman, Olafur Gisli Jonsson, Jakob Bernhard Cohn Maxild, Mikko Niemi, Stefan Söderhäll, Kjeld Schmiegelow and for the Nordic Society of Paediatric Haematology, Oncology (NOPHO)

    Version of Record online : 3 JAN 2014, DOI: 10.1002/pbc.24921