Search Results

There are 26351 results for: content related to: Two double heterozygotes in a South African Afrikaner family: implications for BRCA1 and BRCA2 predictive testing

  1. You have free access to this content
    BRCA1 and BRCA2 germline mutations are frequently demonstrated in both high-risk pancreatic cancer screening and pancreatic cancer cohorts

    Cancer

    Volume 120, Issue 13, 1 July 2014, Pages: 1960–1967, Aimee L. Lucas, Laura E. Frado, Caroline Hwang, Sheila Kumar, Lauren G. Khanna, Elana J. Levinson, John A. Chabot, Wendy K. Chung and Harold Frucht

    Version of Record online : 15 APR 2014, DOI: 10.1002/cncr.28662

  2. A review of a multifactorial probability-based model for classification of BRCA1 and BRCA2 variants of uncertain significance (VUS)

    Human Mutation

    Volume 33, Issue 1, January 2012, Pages: 8–21, Noralane M. Lindor, Lucia Guidugli, Xianshu Wang, Maxime P. Vallée, Alvaro N. A. Monteiro, Sean Tavtigian, David E. Goldgar and Fergus J. Couch

    Version of Record online : 3 NOV 2011, DOI: 10.1002/humu.21627

  3. You have free access to this content
    Unravelling modifiers of breast and ovarian cancer risk for BRCA1 and BRCA2 mutation carriers: update on genetic modifiers

    Journal of Internal Medicine

    Volume 271, Issue 4, April 2012, Pages: 331–343, D. R. Barnes and A. C. Antoniou

    Version of Record online : 23 MAR 2012, DOI: 10.1111/j.1365-2796.2011.02502.x

  4. A diagnostic genetic test for the physical mapping of germline rearrangements in the susceptibility breast cancer genes BRCA1 and BRCA2

    Human Mutation

    Volume 33, Issue 6, June 2012, Pages: 998–1009, Kevin Cheeseman, Etienne Rouleau, Anne Vannier, Aurélie Thomas, Adrien Briaux, Cedrick Lefol, Pierre Walrafen, Aaron Bensimon, Rosette Lidereau, Emmanuel Conseiller and Maurizio Ceppi

    Version of Record online : 4 APR 2012, DOI: 10.1002/humu.22060

  5. You have free access to this content
    Improved survival for BRCA2-associated serous ovarian cancer compared with both BRCA-negative and BRCA1-associated serous ovarian cancer

    Cancer

    Volume 118, Issue 15, 1 August 2012, Pages: 3703–3709, David M. Hyman, Qin Zhou, Alexia Iasonos, Rachel N. Grisham, Angela G. Arnold, Mary F. Phillips, Jasmine Bhatia, Douglas A. Levine, Carol Aghajanian, Kenneth Offit, Richard R. Barakat, David R. Spriggs and Noah D. Kauff

    Version of Record online : 2 DEC 2011, DOI: 10.1002/cncr.26655

  6. Skin cancer risk in BRCA1/2 mutation carriers

    British Journal of Dermatology

    Volume 172, Issue 6, June 2015, Pages: 1498–1506, P.V. Gumaste, L.A. Penn, R.M. Cymerman, T. Kirchhoff, D. Polsky and B. McLellan

    Version of Record online : 29 APR 2015, DOI: 10.1111/bjd.13626

  7. You have free access to this content
    Familial Breast Cancer

    Clinical Genetics

    Volume 82, Issue 2, August 2012, Pages: 105–114, F Lalloo and D G Evans

    Version of Record online : 13 APR 2012, DOI: 10.1111/j.1399-0004.2012.01859.x

  8. A whole-genome massively parallel sequencing analysis of BRCA1 mutant oestrogen receptor-negative and -positive breast cancers

    The Journal of Pathology

    Volume 227, Issue 1, May 2012, Pages: 29–41, Rachael Natrajan, Alan Mackay, Maryou B Lambros, Britta Weigelt, Paul M Wilkerson, Elodie Manie, Anita Grigoriadis, Roger A'Hern, Petra van der Groep, Iwanka Kozarewa, Tatiana Popova, Odette Mariani, Samra Turajlic, Simon J Furney, Richard Marais, Daniel-Nava Rodruigues, Adriana C Flora, Patty Wai, Vidya Pawar, Simon McDade, Jason Carroll, Dominique Stoppa-Lyonnet, Andrew R Green, Ian O Ellis, Charles Swanton, Paul van Diest, Olivier Delattre, Christopher J Lord, William D Foulkes, Anne Vincent-Salomon, Alan Ashworth, Marc Henri Stern and Jorge S Reis-Filho

    Version of Record online : 23 FEB 2012, DOI: 10.1002/path.4003

  9. Identification of BRCA1-deficient ovarian cancers

    Acta Obstetricia et Gynecologica Scandinavica

    Volume 90, Issue 6, June 2011, Pages: 593–599, ANNE-BINE SKYTTE, MARIANNE WALDSTRØM, ANDERS AAMANN RASMUSSEN, DORTHE CRÜGER, EMMA R. WOODWARD and STEEN KØLVRAA

    Version of Record online : 15 APR 2011, DOI: 10.1111/j.1600-0412.2011.01121.x

  10. You have free access to this content
    BRCA1 gene in breast cancer

    Journal of Cellular Physiology

    Volume 196, Issue 1, July 2003, Pages: 19–41, Eliot M. Rosen, Saijun Fan, Richard G. Pestell and Itzhak D. Goldberg

    Version of Record online : 31 MAR 2003, DOI: 10.1002/jcp.10257

  11. You have free access to this content
    The molecular pathogenesis of hereditary ovarian carcinoma

    Cancer

    Volume 116, Issue 22, 15 November 2010, Pages: 5261–5271, Barbara M. Norquist, Rochelle L. Garcia, Kimberly H. Allison, Chris H. Jokinen, Lauren E. Kernochan, Catherine C. Pizzi, Bethany J. Barrow, Barbara A. Goff and Elizabeth M. Swisher

    Version of Record online : 3 NOV 2010, DOI: 10.1002/cncr.25439

  12. Comprehensive mutational analysis of BRCA1/BRCA2 for Korean breast cancer patients: evidence of a founder mutation

    Clinical Genetics

    Volume 76, Issue 2, August 2009, Pages: 152–160, M-W Seong, SI Cho, D-Y Noh, W Han, S-W Kim, C-M Park, H-W Park, SY Kim, JY Kim and SS Park

    Version of Record online : 28 JUL 2009, DOI: 10.1111/j.1399-0004.2009.01202.x

  13. Insights into the targeted elimination of BRCA1-defective cancer stem cells

    Medicinal Research Reviews

    Volume 32, Issue 5, September 2012, Pages: 948–967, Veena Somasundaram and Priya Srinivas

    Version of Record online : 2 SEP 2010, DOI: 10.1002/med.20229

  14. Genotype–Phenotype Correlations by Ethnicity and Mutation Location in BRCA Mutation Carriers

    The Breast Journal

    Volume 21, Issue 3, May/June 2015, Pages: 260–267, Soley Bayraktar, Michelle Jackson, Angelica M. Gutierrez-Barrera, Diane Liu, Funda Meric-Bernstam, Amanda Brandt, Ashley Woodson, Jennifer Litton, Karen H. Lu, Vicente Valero and Banu K. Arun

    Version of Record online : 19 MAR 2015, DOI: 10.1111/tbj.12392

  15. You have free access to this content
    Prevalence of BRCA1 and BRCA2 mutations in Ashkenazi Jewish families with breast and pancreatic cancer

    Cancer

    Volume 118, Issue 2, 15 January 2012, Pages: 493–499, Zsofia K. Stadler, Erin Salo-Mullen, Sujata M. Patil, M. Catherine Pietanza, Joseph Vijai, Emmanouil Saloustros, Nichole A. L. Hansen, Noah D. Kauff, Robert C. Kurtz, David P. Kelsen, Kenneth Offit and Mark E. Robson

    Version of Record online : 19 MAY 2011, DOI: 10.1002/cncr.26191

  16. All in the family: Evaluation of the process and content of sisters' communication about BRCA1 and BRCA2 genetic test results

    American Journal of Medical Genetics

    Volume 107, Issue 2, 15 January 2002, Pages: 143–150, Chanita Hughes, Caryn Lerman, Marc Schwartz, Beth N. Peshkin, Lari Wenzel, Steven Narod, Camille Corio, Kenneth P. Tercyak, Danielle Hanna, Claudine Isaacs and David Main

    Version of Record online : 28 NOV 2001, DOI: 10.1002/ajmg.10110

  17. You have free access to this content
    Disruption of the expected positive correlation between breast tumor size and lymph node status in BRCA1-related breast carcinoma

    Cancer

    Volume 98, Issue 8, 15 October 2003, Pages: 1569–1577, William D. Foulkes, Kelly Metcalfe, Wedad Hanna, Henry T. Lynch, Parviz Ghadirian, Nadine Tung, Olofunmilayo Olopade, Barbara Weber, Jane McLennan, Ivo A. Olivotto, Ping Sun, Pierre O. Chappuis, Louis R. Bégin, Jean-Sébastien Brunet and Steven A. Narod

    Version of Record online : 8 SEP 2003, DOI: 10.1002/cncr.11688

  18. BRCA1/2 testing: uptake, phenocopies, and strategies to improve detection rates in initially negative families

    Clinical Genetics

    Volume 82, Issue 5, November 2012, Pages: 478–483, C Fischer, C Engel, C Sutter, S Zachariae, R Schmutzler, A Meindl, S Heidemann, T Grimm, TO Goecke, I Debatin, D Horn, P Wieacker, D Gadzicki, K Becker, D Schäfer, F Stock, T Voigtländer and on behalf of the German Consortium for Hereditary Breast and Ovarian Cancer

    Version of Record online : 19 OCT 2011, DOI: 10.1111/j.1399-0004.2011.01788.x

  19. You have free access to this content
    BRCA1 and BRCA2 mutations account for a large proportion of ovarian carcinoma cases

    Cancer

    Volume 104, Issue 12, 15 December 2005, Pages: 2807–2816, Tuya Pal, Jenny Permuth-Wey, Judith A. Betts, Jeffrey P. Krischer, James Fiorica, Hector Arango, James LaPolla, Mitchell Hoffman, Martin A. Martino, Katie Wakeley, George Wilbanks, Santo Nicosia, Alan Cantor and Rebecca Sutphen

    Version of Record online : 14 NOV 2005, DOI: 10.1002/cncr.21536

  20. You have full text access to this OnlineOpen article
    Detection of BRCA1 and BRCA2 germline mutations in Japanese population using next-generation sequencing

    Molecular Genetics & Genomic Medicine

    Volume 3, Issue 2, March 2015, Pages: 121–129, Yosuke Hirotsu, Hiroshi Nakagomi, Ikuko Sakamoto, Kenji Amemiya, Hitoshi Mochizuki and Masao Omata

    Version of Record online : 4 DEC 2014, DOI: 10.1002/mgg3.120