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There are 37901 results for: content related to: Ketamine, an NMDA-antagonist, increases the oscillatory frequencies of α-peaks on the electroencephalographic power spectrum

  1. Accurate prediction of basicity in aqueous solution with COSMO-RS

    Journal of Computational Chemistry

    Volume 27, Issue 1, 15 January 2006, Pages: 11–19, Frank Eckert and Andreas Klamt

    Version of Record online : 18 OCT 2005, DOI: 10.1002/jcc.20309

  2. You have full text access to this OnlineOpen article
    A Bayesian Perspective on Estimation of Variability and Uncertainty in Mechanism-Based Models

    CPT: Pharmacometrics & Systems Pharmacology

    Volume 3, Issue 6, June 2014, Pages: 1–3, TA Leil

    Version of Record online : 25 JUN 2014, DOI: 10.1038/psp.2014.19

  3. Application of pharmacokinetics–pharmacodynamics/clinical response modeling and simulation for biologics drug development

    Journal of Pharmaceutical Sciences

    Volume 101, Issue 12, December 2012, Pages: 4367–4382, Liang Zhao, Elizabeth Y. Shang and Chandrahas G. Sahajwalla

    Version of Record online : 27 SEP 2012, DOI: 10.1002/jps.23330

  4. The application of mechanism-based PK/PD modeling in pharmacodynamic-based dose selection of muM17, a surrogate monoclonal antibody for efalizumab

    Journal of Pharmaceutical Sciences

    Volume 95, Issue 6, June 2006, Pages: 1258–1268, Benjamin Wu, Amita Joshi, Song Ren and Chee Ng

    Version of Record online : 24 APR 2006, DOI: 10.1002/jps.20475

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    Issues, challenges, and opportunities in model-based drug development for monoclonal antibodies

    Journal of Pharmaceutical Sciences

    Volume 102, Issue 9, September 2013, Pages: 2898–2908 , Leijun Hu and Ryan J. Hansen

    Version of Record online : 18 MAR 2013, DOI: 10.1002/jps.23504

  6. Mutant prevention concentration, pharmacokinetic–pharmacodynamic integration, and modeling of enrofloxacin data established in diseased buffalo calves

    Journal of Veterinary Pharmacology and Therapeutics

    Volume 38, Issue 6, December 2015, Pages: 529–536, B. Ramalingam, P. K. Sidhu, G. Kaur, D. Venkatachalam and S. Rampal

    Version of Record online : 16 MAR 2015, DOI: 10.1111/jvp.12223

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    A comparison of propofol and sevoflurane anaesthesia: effects on aortic blood flow velocity and middle cerebral artery blood flow velocity


    Volume 58, Issue 3, March 2003, Pages: 217–222, A. Holzer, W. Winter, M. Greher, M. Reddy, J. Stark, A. Donner, M. Zimpfer and U. M. Illievich

    Version of Record online : 21 FEB 2003, DOI: 10.1046/j.1365-2044.2003.03041.x

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    At the bench: the key role of PK–PD modelling in enabling the early discovery of biologic therapies

    British Journal of Clinical Pharmacology

    Volume 77, Issue 5, May 2014, Pages: 740–745, Mark Penney and Balaji Agoram

    Version of Record online : 22 APR 2014, DOI: 10.1111/bcp.12225

  9. Mechanism-Based Pharmacokinetic–Pharmacodynamic Modeling During Discovery and Early Development

    Systems Biology in Drug Discovery and Development

    Hans Peter Grimm, Ying Ou, Micaela Reddy, Pascale David-Pierson, Thierry Lavé, Pages: 175–199, 2011

    Published Online : 7 NOV 2011, DOI: 10.1002/9781118016435.ch8

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    Paediatric models in motion: requirements for model-based decision support at the bedside

    British Journal of Clinical Pharmacology

    Volume 79, Issue 1, January 2015, Pages: 85–96, Jeffrey S. Barrett

    Version of Record online : 19 DEC 2014, DOI: 10.1111/bcp.12287

  11. Utility of free and total target measurements as target engagement and efficacy biomarkers in biotherapeutic development—Opportunities and challenges

    The Journal of Clinical Pharmacology

    Volume 55, Issue S3, March 2015, Pages: S75–S84, Songmao Zheng, Thomas McIntosh and Weirong Wang

    Version of Record online : 23 FEB 2015, DOI: 10.1002/jcph.357

  12. Punch planting, flame weeding and delayed sowing to reduce intra-row weeds in row crops

    Weed Research

    Volume 51, Issue 5, October 2011, Pages: 489–498, J RASMUSSEN, C B HENRIKSEN, H W GRIEPENTROG and J NIELSEN

    Version of Record online : 3 APR 2011, DOI: 10.1111/j.1365-3180.2011.00858.x

  13. Predicting Drug Interaction Potential With a Physiologically Based Pharmacokinetic Model: A Case Study of Telithromycin, a Time-Dependent CYP3A Inhibitor

    Clinical Pharmacology & Therapeutics

    Volume 91, Issue 4, April 2012, Pages: 700–708, Md L T Vieira, P Zhao, E G Berglund, K S Reynolds, L Zhang, L J Lesko and S-M Huang

    Version of Record online : 7 MAR 2012, DOI: 10.1038/clpt.2011.305

  14. Multilayer composite surfaces prepared by an electrostatic self-assembly technique with quaternary ammonium salt and poly(acrylic acid) on poly(acrylonitrile-co-acrylic acid) membranes

    Journal of Applied Polymer Science

    Volume 110, Issue 5, 5 December 2008, Pages: 3234–3241, Takaomi Kobayashi, Huitan Fu, Qian Cui and Hongying Wang

    Version of Record online : 8 SEP 2008, DOI: 10.1002/app.28849

  15. A Framework for Meta-Analysis of Veterinary Drug Pharmacokinetic Data Using Mixed Effect Modeling

    Journal of Pharmaceutical Sciences

    Volume 104, Issue 4, April 2015, Pages: 1230–1239, Mengjie Li, Ronette Gehring, Zhoumeng Lin and Jim Riviere

    Version of Record online : 12 JAN 2015, DOI: 10.1002/jps.24341

  16. Pharmacokinetic and pharmacodynamic analysis comparing diverse effects of detomidine, medetomidine, and dexmedetomidine in the horse: a population analysis

    Journal of Veterinary Pharmacology and Therapeutics

    Volume 38, Issue 1, February 2015, Pages: 24–34, K. N. Grimsrud, S. Ait-Oudhia, B. P. Durbin-Johnson, D. M. Rocke, K. R. Mama, M. L. Rezende, S. D. Stanley and W. J. Jusko

    Version of Record online : 29 JUL 2014, DOI: 10.1111/jvp.12139

  17. Hypnotic endpoints vs. the bispectral index,95% spectral edge frequency and median frequency during propofol infusion with or without fentanyl

    European Journal of Anaesthesiology

    Volume 16, Issue 1, January 1999, Pages: 47–52, W. D. Mi, T. Sakai, H. Singh, T. Kudo, M. Kudo and A. Matsuki

    Version of Record online : 11 JAN 2002, DOI: 10.1046/j.1365-2346.1999.00421.x

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    Use of pharmacokinetic/ pharmacodynamic modelling for starting dose selection in first-in-human trials of high-risk biologics

    British Journal of Clinical Pharmacology

    Volume 67, Issue 2, February 2009, Pages: 153–160, Balaji M. Agoram

    Version of Record online : 3 SEP 2008, DOI: 10.1111/j.1365-2125.2008.03297.x

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    A study of bispectral analysis and auditory evoked potential indices during propofol-induced hypnosis in volunteersThe effect of an episode of wakefulness on explicit and implicit memory


    Volume 56, Issue 9, September 2001, Pages: 888–892, G. Barr, R. E. Anderson and J. G. Jakobsson

    Version of Record online : 6 AUG 2008, DOI: 10.1046/j.1365-2044.2001.02059-3.x

  20. Pharmacokinetic Data Analysis and Modeling of ADME Processes

    Standard Article

    Encyclopedia of Drug Metabolism and Interactions

    Steven Zhang

    Published Online : 15 OCT 2012, DOI: 10.1002/9780470921920.edm035