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There are 14825 results for: content related to: Mutations in the NS5B region of the hepatitis C virus genome correlate with clinical outcomes of interferon-alpha plus ribavirin combination therapy

  1. Monoclonal antibody recognizing N-terminal epitope of hepatitis C virus nonstructural 5B inhibits viral RNA replication

    Journal of Viral Hepatitis

    Volume 15, Issue 4, April 2008, Pages: 305–313, S. M. Kang, S. H. Choi, C. Y. Park, M. H. Kim, T. K. Kim, J. M. Park, M. S. Koh, H. J. Kang and S. B. Hwang

    Article first published online : 12 DEC 2007, DOI: 10.1111/j.1365-2893.2007.00945.x

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    C-Src is required for complex formation between the hepatitis C virus–encoded proteins NS5A and NS5B: A prerequisite for replication


    Volume 53, Issue 4, April 2011, Pages: 1127–1136, Andreas Pfannkuche, Katrin Büther, Juliane Karthe, Marion Poenisch, Ralf Bartenschlager, Mirko Trilling, Hartmut Hengel, Dieter Willbold, Dieter Häussinger and Johannes Georg Bode

    Article first published online : 7 APR 2011, DOI: 10.1002/hep.24214

  3. Site-specific cleavage of HCV genomic RNA and its cloned core and NS5B genes by DNAzyme

    Journal of Gastroenterology and Hepatology

    Volume 24, Issue 5, May 2009, Pages: 872–878, Deepak Kumar, Indrajit Chaudhury, Premashis Kar and Rakha H Das

    Article first published online : 9 FEB 2009, DOI: 10.1111/j.1440-1746.2008.05717.x

  4. Discovery of N-Arylalkyl-3-hydroxy-4-oxo-3,4-dihydroquinazolin-2-carboxamide Derivatives as HCV NS5B Polymerase Inhibitors


    Volume 7, Issue 5, May 2012, Pages: 850–860, Dr. Ravindra Ramesh Deore, Prof. Grace Shiahuy Chen, Dr. Pei-Teh Chang, Ting-Rong Chern, Dr. Shin-Yu Lai, Ming-Hsieh Chuang, Prof. Jung-Hsin Lin, Prof. Fan-Lu Kung, Prof. Chien-Shu Chen, Dr. Chun-Tang Chiou and Prof. Ji-Wang Chern

    Article first published online : 1 MAR 2012, DOI: 10.1002/cmdc.201200058

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    Specific interaction between the classical swine fever virus NS5B protein and the viral genome

    European Journal of Biochemistry

    Volume 271, Issue 19, October 2004, Pages: 3888–3896, Ming Xiao, Jufang Gao, Wei Wang, Yujing Wang, Jun Chen, Jiakuan Chen and Bo Li

    Article first published online : 6 SEP 2004, DOI: 10.1111/j.1432-1033.2004.04325.x

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    Template requirements and binding of hepatitis C virus NS5B polymerase during in vitro RNA synthesis from the 3′-end of virus minus-strand RNA

    FEBS Journal

    Volume 272, Issue 15, August 2005, Pages: 3872–3886, Thérèse Astier-Gin, Pantxika Bellecave, Simon Litvak and Michel Ventura

    Article first published online : 19 JUL 2005, DOI: 10.1111/j.1742-4658.2005.04804.x

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    Hepatitis C virus internal ribosome entry site-mediated translation is stimulated by cis-acting RNA elements and trans-acting viral factors

    FEBS Journal

    Volume 275, Issue 16, August 2008, Pages: 4179–4197, Sofia Lourenço, Fleur Costa, Béatrice Débarges, Thibault Andrieu and Annie Cahour

    Article first published online : 11 JUL 2008, DOI: 10.1111/j.1742-4658.2008.06566.x

  8. Natural prevalence of hepatitis C virus (HCV) variants resistant to protease and polymerase inhibitors in patients infected with HCV genotype 1 in Tunisia

    Journal of Medical Virology

    Volume 86, Issue 8, August 2014, Pages: 1350–1359, Jameleddine Aissa Larousse, Pascale Trimoulet, Patricia Recordon-Pinson, Jennnifer Papuchon, Mohamed Mssadak Azzouz, Nabyl Ben Mami, Imed Cheikh, Henda Triki and Hervé Fleury

    Article first published online : 24 APR 2014, DOI: 10.1002/jmv.23958

  9. Evaluation of Coumarin and Neoflavone Derivatives as HCV NS5B Polymerase Inhibitors

    Chemical Biology & Drug Design

    Volume 81, Issue 5, May 2013, Pages: 607–614, Daniel B. Nichols, Raquel A. C. Leão, Amartya Basu, Maksim Chudayeu, Paula de F. de Moraes, Tanaji T. Talele, Paulo R. R. Costa and Neerja Kaushik-Basu

    Article first published online : 4 APR 2013, DOI: 10.1111/cbdd.12105

  10. Analysis of a non-structural gene reveals evidence of possible hepatitis C virus (HCV) compartmentalization

    Journal of Medical Virology

    Volume 84, Issue 2, February 2012, Pages: 242–252, Jason T. Blackard, Gang Ma, Jeffrey A. Welge, Christina M. Martin, Kenneth E. Sherman, Lynn E. Taylor, Kenneth H. Mayer and Denise J. Jamieson

    Article first published online : 14 DEC 2011, DOI: 10.1002/jmv.22269

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    Antiviral effects of the interferon-induced protein guanylate binding protein 1 and its interaction with the hepatitis C virus NS5B protein


    Volume 50, Issue 6, December 2009, Pages: 1727–1737, Yasuhiro Itsui, Naoya Sakamoto, Sei Kakinuma, Mina Nakagawa, Yuko Sekine-Osajima, Megumi Tasaka-Fujita, Yuki Nishimura-Sakurai, Gouki Suda, Yuko Karakama, Kako Mishima, Machi Yamamoto, Takako Watanabe, Mayumi Ueyama, Yusuke Funaoka, Seishin Azuma and Mamoru Watanabe

    Article first published online : 5 AUG 2009, DOI: 10.1002/hep.23195

  12. Thumb inhibitor binding eliminates functionally important dynamics in the hepatitis C virus RNA polymerase

    Proteins: Structure, Function, and Bioinformatics

    Volume 81, Issue 1, January 2013, Pages: 40–52, Brittny C. Davis and Ian F. Thorpe

    Article first published online : 15 SEP 2012, DOI: 10.1002/prot.24154

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    Mutations in the hepatitis C virus polymerase that increase RNA binding can confer resistance to cyclosporine A


    Volume 50, Issue 1, July 2009, Pages: 25–33, Zhe Liu, John M. Robida, Sreedhar Chinnaswamy, Guanghui Yi, Jason M. Robotham, Heather B. Nelson, Andre Irsigler, C. Cheng Kao and Hengli Tang

    Article first published online : 6 APR 2009, DOI: 10.1002/hep.22987

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    Sensitivity of hepatitis C virus to cyclosporine A depends on nonstructural proteins NS5A and NS5B


    Volume 46, Issue 4, October 2007, Pages: 1026–1033, Fiona Fernandes, Daniel S. Poole, Spencer Hoover, Rannveig Middleton, Adin-Cristian Andrei, Justin Gerstner and Rob Striker

    Article first published online : 28 JUN 2007, DOI: 10.1002/hep.21809

  15. Effective epitope identification employing phylogenetic, mutational variability, sequence entropy, and correlated mutation analysis targeting NS5B protein of hepatitis C virus: from bioinformatics to therapeutics

    Journal of Molecular Recognition

    Volume 28, Issue 8, August 2015, Pages: 492–505, Rohan J. Meshram and Rajesh N. Gacche

    Article first published online : 27 FEB 2015, DOI: 10.1002/jmr.2466

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    De novo RNA synthesis by a recombinant classical swine fever virus RNA-dependent RNA polymerase

    European Journal of Biochemistry

    Volume 270, Issue 24, December 2003, Pages: 4952–4961, Guang-Hui Yi, Chu-Yu Zhang, Sheng Cao, Hai-Xiang Wu and Yi Wang

    Article first published online : 2 DEC 2003, DOI: 10.1046/j.1432-1033.2003.03897.x

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    Poster Session 4: Hepatitis C: Preclinical Development


    Volume 60, Issue S1, October 2014, Pages: 1161A–1173A,

    Article first published online : 1 OCT 2014, DOI: 10.1002/hep.27534

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    Treating hepatitis C: Can you teach old dogs new tricks?


    Volume 42, Issue 6, December 2005, Pages: 1455–1458, Charles M. Rice and Shihyun You

    Article first published online : 29 NOV 2005, DOI: 10.1002/hep.20975

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    Clinical evidence and bioinformatics characterization of potential hepatitis C virus resistance pathways for sofosbuvir


    Volume 61, Issue 1, January 2015, Pages: 56–65, Eric F. Donaldson, Patrick R. Harrington, Julian J. O'Rear and Lisa K. Naeger

    Article first published online : 20 NOV 2014, DOI: 10.1002/hep.27375

  20. Combined 3D-QSAR, Molecular Docking, Molecular Dynamics Simulation, and Binding Free Energy Calculation Studies on the 5-Hydroxy-2H-Pyridazin-3-One Derivatives as HCV NS5B Polymerase Inhibitors

    Chemical Biology & Drug Design

    Volume 83, Issue 1, January 2014, Pages: 89–105, Haijing Yu, Yu Fang, Xia Lu, Yongjuan Liu and Huabei Zhang

    Article first published online : 4 OCT 2013, DOI: 10.1111/cbdd.12203