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There are 23284 results for: content related to: Increased incidence of brain metastases in BRCA1 -related ovarian cancers

  1. You have free access to this content
    ATM–Chk2–p53 activation prevents tumorigenesis at an expense of organ homeostasis upon Brca1 deficiency

    The EMBO Journal

    Volume 25, Issue 10, May 17, 2006, Pages: 2167–2177, Liu Cao, Sangsoo Kim, Cuiying Xiao, Rui-Hong Wang, Xavier Coumoul, Xiaoyan Wang, Wen Mei Li, Xiao Ling Xu, Joseph A De Soto, Hiroyuki Takai, Sabine Mai, Stephen J Elledge, Noboru Motoyama and Chu-Xia Deng

    Version of Record online : 4 MAY 2006, DOI: 10.1038/sj.emboj.7601115

  2. You have full text access to this Open Access content
    The Contribution of BRCA1 and BRCA2 to Ovarian Cancer

    Molecular Oncology

    Volume 3, Issue 2, April 2009, Pages: 138–150, Susan J. Ramus, Simon A. Gayther

    Version of Record online : 10 FEB 2009, DOI: 10.1016/j.molonc.2009.02.001

  3. You have full text access to this Open Access content
    Proper genomic profiling of (BRCA1-mutated) basal-like breast carcinomas requires prior removal of tumor infiltrating lymphocytes

    Molecular Oncology

    Volume 9, Issue 4, April 2015, Pages: 877–888, Maarten P.G. Massink, Irsan E. Kooi, Saskia E. van Mil, Ekaterina S. Jordanova, Najim Ameziane, Josephine C. Dorsman, Daphne M. van Beek, J. Patrick van der Voorn, Daoud Sie, Bauke Ylstra, Carolien H.M. van Deurzen, John W. Martens, Marcel Smid, Anieta M. Sieuwerts, Vanja de Weerd, John A. Foekens, Ans M.W. van den Ouweland, Ewald van Dyk, Petra M. Nederlof, Quinten Waisfisz, Hanne Meijers-Heijboer

    Version of Record online : 13 JAN 2015, DOI: 10.1016/j.molonc.2014.12.012

  4. BRCA1 alterations with additional defects in DNA damage response genes may confer chemoresistance to BRCA-like breast cancers treated with neoadjuvant chemotherapy

    Genes, Chromosomes and Cancer

    Volume 56, Issue 5, May 2017, Pages: 405–420, Mamoru Takada, Shigenori Nagai, Masayuki Haruta, Ryuichi P. Sugino, Katsunori Tozuka, Hiroyuki Takei, Fumie Ohkubo, Kenichi Inoue, Masafumi Kurosumi, Masaru Miyazaki, Aiko Sato-Otsubo, Yusuke Sato, Seishi Ogawa and Yasuhiko Kaneko

    Version of Record online : 7 MAR 2017, DOI: 10.1002/gcc.22445

  5. A diagnostic genetic test for the physical mapping of germline rearrangements in the susceptibility breast cancer genes BRCA1 and BRCA2

    Human Mutation

    Volume 33, Issue 6, June 2012, Pages: 998–1009, Kevin Cheeseman, Etienne Rouleau, Anne Vannier, Aurélie Thomas, Adrien Briaux, Cedrick Lefol, Pierre Walrafen, Aaron Bensimon, Rosette Lidereau, Emmanuel Conseiller and Maurizio Ceppi

    Version of Record online : 4 APR 2012, DOI: 10.1002/humu.22060

  6. You have full text access to this OnlineOpen article
    Novel BRCA1 and BRCA2 Tumor Test as Basis for Treatment Decisions and Referral for Genetic Counselling of Patients with Ovarian Carcinomas

    Human Mutation

    Volume 38, Issue 2, February 2017, Pages: 226–235, Robbert D.A. Weren, Arjen R. Mensenkamp, Michiel Simons, Astrid Eijkelenboom, Aisha S. Sie, Hicham Ouchene, Monique van Asseldonk, Encarna B. Gomez-Garcia, Marinus J. Blok, Joanne A. de Hullu, Marcel R. Nelen, Alexander Hoischen, Johan Bulten, Bastiaan B.J. Tops, Nicoline Hoogerbrugge and Marjolijn J.L. Ligtenberg

    Version of Record online : 9 NOV 2016, DOI: 10.1002/humu.23137

  7. Identification of fifteen novel germline variants in the BRCA1 3′UTR reveals a variant in a breast cancer case that introduces a functional miR-103 target site

    Human Mutation

    Volume 33, Issue 12, December 2012, Pages: 1665–1675, Brooke L. Brewster, Francesca Rossiello, Juliet D. French, Stacey L. Edwards, Ming Wong, Ania Wronski, Phillip Whiley, Nic Waddell, Xiaowei Chen, Betsy Bove, kConFab, John L. Hopper, Esther M. John, Irene Andrulis, Mary Daly, Sara Volorio, Loris Bernard, Bernard Peissel, Siranoush Manoukian, Monica Barile, Sara Pizzamiglio, Paolo Verderio, Amanda B. Spurdle, Paolo Radice, Andrew K. Godwin, Melissa C Southey, Melissa A. Brown and Paolo Peterlongo

    Version of Record online : 2 AUG 2012, DOI: 10.1002/humu.22159

  8. Multiple copies of mutant BRCA1 and BRCA2 alleles in breast tumors from germ-line mutation carriers

    Genes, Chromosomes and Cancer

    Volume 28, Issue 4, August 2000, Pages: 432–442, Synnöve Staff, Nina N. Nupponen, Åke Borg, Jorma J. Isola and Minna M. Tanner

    Version of Record online : 14 JUN 2000, DOI: 10.1002/1098-2264(200008)28:4<432::AID-GCC9>3.0.CO;2-J

  9. A whole-genome massively parallel sequencing analysis of BRCA1 mutant oestrogen receptor-negative and -positive breast cancers

    The Journal of Pathology

    Volume 227, Issue 1, May 2012, Pages: 29–41, Rachael Natrajan, Alan Mackay, Maryou B Lambros, Britta Weigelt, Paul M Wilkerson, Elodie Manie, Anita Grigoriadis, Roger A'Hern, Petra van der Groep, Iwanka Kozarewa, Tatiana Popova, Odette Mariani, Samra Turajlic, Simon J Furney, Richard Marais, Daniel-Nava Rodruigues, Adriana C Flora, Patty Wai, Vidya Pawar, Simon McDade, Jason Carroll, Dominique Stoppa-Lyonnet, Andrew R Green, Ian O Ellis, Charles Swanton, Paul van Diest, Olivier Delattre, Christopher J Lord, William D Foulkes, Anne Vincent-Salomon, Alan Ashworth, Marc Henri Stern and Jorge S Reis-Filho

    Version of Record online : 23 FEB 2012, DOI: 10.1002/path.4003

  10. Identification of BRCA1-deficient ovarian cancers

    Acta Obstetricia et Gynecologica Scandinavica

    Volume 90, Issue 6, June 2011, Pages: 593–599, ANNE-BINE SKYTTE, MARIANNE WALDSTRØM, ANDERS AAMANN RASMUSSEN, DORTHE CRÜGER, EMMA R. WOODWARD and STEEN KØLVRAA

    Version of Record online : 15 APR 2011, DOI: 10.1111/j.1600-0412.2011.01121.x

  11. You have free access to this content
    The molecular pathogenesis of hereditary ovarian carcinoma

    Cancer

    Volume 116, Issue 22, 15 November 2010, Pages: 5261–5271, Barbara M. Norquist, Rochelle L. Garcia, Kimberly H. Allison, Chris H. Jokinen, Lauren E. Kernochan, Catherine C. Pizzi, Bethany J. Barrow, Barbara A. Goff and Elizabeth M. Swisher

    Version of Record online : 3 NOV 2010, DOI: 10.1002/cncr.25439

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    Disruption of the expected positive correlation between breast tumor size and lymph node status in BRCA1-related breast carcinoma

    Cancer

    Volume 98, Issue 8, 15 October 2003, Pages: 1569–1577, William D. Foulkes, Kelly Metcalfe, Wedad Hanna, Henry T. Lynch, Parviz Ghadirian, Nadine Tung, Olofunmilayo Olopade, Barbara Weber, Jane McLennan, Ivo A. Olivotto, Ping Sun, Pierre O. Chappuis, Louis R. Bégin, Jean-Sébastien Brunet and Steven A. Narod

    Version of Record online : 8 SEP 2003, DOI: 10.1002/cncr.11688

  13. You have full text access to this OnlineOpen article
    BRCA1-like signature in triple negative breast cancer: Molecular and clinical characterization reveals subgroups with therapeutic potential

    Molecular Oncology

    Volume 9, Issue 8, October 2015, Pages: 1528–1538, Tesa M. Severson, Justine Peeters, Ian Majewski, Magali Michaut, Astrid Bosma, Philip C. Schouten, Suet-Feung Chin, Bernard Pereira, Mae A. Goldgraben, Tycho Bismeijer, Roelof J.C. Kluin, Jettie J.F. Muris, Karin Jirström, Ron M. Kerkhoven, Lodewyk Wessels, Carlos Caldas, René Bernards, Iris M. Simon, Sabine Linn

    Version of Record online : 7 MAY 2015, DOI: 10.1016/j.molonc.2015.04.011

  14. BRCA1-Mediated Inflammation and Growth Activated & Inhibited Transition Mechanisms Between No-Tumor Hepatitis/Cirrhotic Tissues and HCC

    Journal of Cellular Biochemistry

    Volume 115, Issue 4, April 2014, Pages: 641–650, Haizhen Diao, Lin Wang, Juxiang Huang, Minghu Jiang, Huilei Zhou, Xiaohe Li, Qingchun Chen, Zhenfu Jiang and Haitao Feng

    Version of Record online : 23 JAN 2014, DOI: 10.1002/jcb.24699

  15. The spectrum of BRCA mutations and characteristics of BRCA-associated breast cancers in China: Screening of 2,991 patients and 1,043 controls by next-generation sequencing

    International Journal of Cancer

    Volume 141, Issue 1, 01 July 2017, Pages: 129–142, Guan-Tian Lang, Jin-Xiu Shi, Xin Hu, Chen-Hui Zhang, Ling Shan, Chuan-Gui Song, Zhi-Gang Zhuang, A-Yong Cao, Hong Ling, Ke-Da Yu, Shan Li, Meng-Hong Sun, Xiao-Yan Zhou, Wei Huang and Zhi-Ming Shao

    Version of Record online : 25 APR 2017, DOI: 10.1002/ijc.30692

  16. You have full text access to this Open Access content
    Hereditary ovarian carcinoma: Heterogeneity, molecular genetics, pathology, and management

    Molecular Oncology

    Volume 3, Issue 2, April 2009, Pages: 97–137, Henry T. Lynch, Murray Joseph Casey, Carrie L. Snyder, Chhanda Bewtra, Jane F. Lynch, Matthew Butts, Andrew K. Godwin

    Version of Record online : 21 FEB 2009, DOI: 10.1016/j.molonc.2009.02.004

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    Unravelling modifiers of breast and ovarian cancer risk for BRCA1 and BRCA2 mutation carriers: update on genetic modifiers

    Journal of Internal Medicine

    Volume 271, Issue 4, April 2012, Pages: 331–343, D. R. Barnes and A. C. Antoniou

    Version of Record online : 23 MAR 2012, DOI: 10.1111/j.1365-2796.2011.02502.x

  18. E2F3b over-expression in ovarian carcinomas and in BRCA1 Haploinsufficient fallopian tube epithelium

    Genes, Chromosomes and Cancer

    Volume 51, Issue 11, November 2012, Pages: 1054–1062, Na Lu Smith, Piri Welcsh, Joshua Z. Press, Kathy J. Agnew, Rochelle Garcia and Elizabeth M. Swisher

    Version of Record online : 9 AUG 2012, DOI: 10.1002/gcc.21990

  19. Germ-line mutations in BRCA1 or BRCA2 in the normal breast are associated with altered expression of estrogen-responsive proteins and the predominance of progesterone receptor A

    Genes, Chromosomes and Cancer

    Volume 39, Issue 3, March 2004, Pages: 236–248, Patricia A. Mote, Jennifer A. Leary, Kelly A. Avery, Kerstin Sandelin, Georgia Chenevix-Trench, Judy A. Kirk and Christine L. Clarke

    Version of Record online : 8 JAN 2004, DOI: 10.1002/gcc.10321

  20. Genomic signature of BRCA1 deficiency in sporadic basal-like breast tumors

    Genes, Chromosomes and Cancer

    Volume 50, Issue 2, February 2011, Pages: 71–81, Simon A. Joosse, Kim I. M. Brandwijk, Lennart Mulder, Jelle Wesseling, Juliane Hannemann and Petra M. Nederlof

    Version of Record online : 22 NOV 2010, DOI: 10.1002/gcc.20833