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There are 3056 results for: content related to: Akt is altered in an animal model of Huntington's disease and in patients

  1. You have full text access to this OnlineOpen article
    The Huntington disease protein accelerates breast tumour development and metastasis through ErbB2/HER2 signalling

    EMBO Molecular Medicine

    Volume 5, Issue 2, February 2013, Pages: 309–325, Cristovão Moreira Sousa, John Russel McGuire, Morgane Sonia Thion, David Gentien, Pierre de la Grange, Sophie Tezenas du Montcel, Anne Vincent-Salomon, Alexandra Durr and Sandrine Humbert

    Version of Record online : 9 JAN 2013, DOI: 10.1002/emmm.201201546

  2. You have free access to this content
    Mutant huntingtin-impaired degradation of β-catenin causes neurotoxicity in Huntington's disease

    The EMBO Journal

    Volume 29, Issue 14, July 21, 2010, Pages: 2433–2445, Juliette D Godin, Ghislaine Poizat, Miriam A Hickey, Florence Maschat and Sandrine Humbert

    Version of Record online : 8 JUN 2010, DOI: 10.1038/emboj.2010.117

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    Polyglutamine expansion in huntingtin alters its interaction with phospholipids

    Journal of Neurochemistry

    Volume 110, Issue 5, September 2009, Pages: 1585–1597, Kimberly B. Kegel, Ellen Sapp, Jonathan Alexander, Antonio Valencia, Patrick Reeves, Xueyi Li, Nicholas Masso, Lindsay Sobin, Neil Aronin and Marian DiFiglia

    Version of Record online : 29 JUN 2009, DOI: 10.1111/j.1471-4159.2009.06255.x

  4. The serum- and glucocorticoid-induced kinase SGK inhibits mutant huntingtin-induced toxicity by phosphorylating serine 421 of huntingtin

    European Journal of Neuroscience

    Volume 19, Issue 2, January 2004, Pages: 273–279, Hélène Rangone, Ghislaine Poizat, Juan Troncoso, Christopher A. Ross, Marcy E. MacDonald, Frédéric Saudou and Sandrine Humbert

    Version of Record online : 16 JAN 2004, DOI: 10.1111/j.0953-816X.2003.03131.x

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    Huntingtin inhibits caspase-3 activation

    The EMBO Journal

    Volume 25, Issue 24, December 13, 2006, Pages: 5896–5906, Yu Zhang, Blair R Leavitt, Jeremy M van Raamsdonk, Ioannis Dragatsis, Dan Goldowitz, Marcy E MacDonald, Michael R Hayden and Robert M Friedlander

    Version of Record online : 23 NOV 2006, DOI: 10.1038/sj.emboj.7601445

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    Protein misfolding inside cells: The case of huntingtin and Huntington's disease

    IUBMB Life

    Volume 60, Issue 11, November 2008, Pages: 724–728, Danny M. Hatters

    Version of Record online : 28 AUG 2008, DOI: 10.1002/iub.111

  7. Challenges of Huntington's disease and quest for therapeutic biomarkers

    PROTEOMICS - Clinical Applications

    Volume 9, Issue 1-2, February 2015, Pages: 147–158, Eva Kotrcova, Karla Jarkovska, Ivona Valekova, Martina Zizkova, Jan Motlik, Suresh Jivan Gadher and Hana Kovarova

    Version of Record online : 2 NOV 2014, DOI: 10.1002/prca.201400073

  8. Reduced expression of the TrkB receptor in Huntington's disease mouse models and in human brain

    European Journal of Neuroscience

    Volume 23, Issue 3, February 2006, Pages: 649–658, Silvia Ginés, Miquel Bosch, Sonia Marco, Núria Gavaldà, Miguel Díaz-Hernández, José J. Lucas, Josep M. Canals and Jordi Alberch

    Version of Record online : 16 FEB 2006, DOI: 10.1111/j.1460-9568.2006.04590.x

  9. Mechanisms of neurodegeneration in Huntington’s disease

    European Journal of Neuroscience

    Volume 27, Issue 11, June 2008, Pages: 2803–2820, Joana M. Gil and Ana Cristina Rego

    Version of Record online : 28 JUN 2008, DOI: 10.1111/j.1460-9568.2008.06310.x

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    Mechanisms of neurodegeneration in Huntington’s disease

    Vol. 28, Issue 10, 2156, Version of Record online: 12 NOV 2008

  10. The composition of the polyglutamine-containing proteins influences their co-aggregation properties

    Cell Biology International

    Volume 34, Issue 9, September 2010, Pages: 933–942, Daniel Bąk and Michał Milewski

    Version of Record online : 2 JAN 2013, DOI: 10.1042/CBI20090474

  11. You have full text access to this OnlineOpen article
    Neuroprotective Effects of Calmodulin Peptide 76-121aa: Disruption of Calmodulin Binding to Mutant Huntingtin

    Brain Pathology

    Volume 20, Issue 1, January 2010, Pages: 176–189, Nichole L. Dudek, Ying Dai and Nancy A. Muma

    Version of Record online : 11 MAR 2009, DOI: 10.1111/j.1750-3639.2008.00258.x

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    Neuroprotective potential of CB1 receptor agonists in an in vitro model of Huntington's disease

    British Journal of Pharmacology

    Volume 160, Issue 3, June 2010, Pages: 747–761, EL Scotter, CE Goodfellow, ES Graham, M Dragunow and M Glass

    Version of Record online : 25 MAR 2010, DOI: 10.1111/j.1476-5381.2010.00773.x

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    Inclusion formation in Huntington's disease R6/2 mouse muscle cultures

    Journal of Neurochemistry

    Volume 87, Issue 1, October 2003, Pages: 1–6, M. Orth, J. M. Cooper, G. P. Bates and A. H. V. Schapira

    Version of Record online : 4 SEP 2003, DOI: 10.1046/j.1471-4159.2003.02009.x

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    Calcineurin is involved in the early activation of NMDA-mediated cell death in mutant huntingtin knock-in striatal cells

    Journal of Neurochemistry

    Volume 105, Issue 5, June 2008, Pages: 1596–1612, Xavier Xifró, Juan Manuel García-Martínez, Daniel Del Toro, Jordi Alberch and Esther Pérez-Navarro

    Version of Record online : 24 JAN 2008, DOI: 10.1111/j.1471-4159.2008.05252.x

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    Allele-specific silencing of mutant Huntington’s disease gene

    Journal of Neurochemistry

    Volume 108, Issue 1, January 2009, Pages: 82–90, Yu Zhang, Joshua Engelman and Robert M. Friedlander

    Version of Record online : 15 OCT 2008, DOI: 10.1111/j.1471-4159.2008.05734.x

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    Huntington’s disease: revisiting the aggregation hypothesis in polyglutamine neurodegenerative diseases

    The FEBS Journal

    Volume 275, Issue 17, September 2008, Pages: 4252–4262, Ray Truant, Randy Singh Atwal, Carly Desmond, Lise Munsie and Thu Tran

    Version of Record online : 15 JUL 2008, DOI: 10.1111/j.1742-4658.2008.06561.x

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    Life Without Huntingtin

    Journal of Neurochemistry

    Volume 72, Issue 3, March 1999, Pages: 1009–1018, Martina Metzler, Nansheng Chen, Cheryl D Helgason, Rona K. Graham, Kerrie Nichol, Krista McCutcheon, Jamal Nasir, R. Keith Humphries, Lynn A. Raymond and Michael R. Hayden

    Version of Record online : 7 JUL 2008, DOI: 10.1046/j.1471-4159.1999.0721009.x

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    Depletion of wild-type huntingtin in mouse models of neurologic diseases

    Journal of Neurochemistry

    Volume 87, Issue 1, October 2003, Pages: 101–106, Yu Zhang, Mingwei Li, Martin Drozda, Minghua Chen, Shengjun Ren, Rene O. Mejia Sanchez, Blair R. Leavitt, Elena Cattaneo, Robert J. Ferrante, Michael R. Hayden and Robert M. Friedlander

    Version of Record online : 12 SEP 2003, DOI: 10.1046/j.1471-4159.2003.01980.x

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    Modulating huntingtin half-life alters polyglutamine-dependent aggregate formation and cell toxicity

    Journal of Neurochemistry

    Volume 89, Issue 4, May 2004, Pages: 962–973, Michael D. Kaytor, Keith D. Wilkinson and Stephen T. Warren

    Version of Record online : 6 APR 2004, DOI: 10.1111/j.1471-4159.2004.02376.x

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    Huntingtin proteolysis releases non-polyQ fragments that cause toxicity through dynamin 1 dysregulation

    The EMBO Journal

    Volume 34, Issue 17, 2 September 2015, Pages: 2255–2271, Marie-Thérèse El-Daher, Emilie Hangen, Julie Bruyère, Ghislaine Poizat, Ismael Al-Ramahi, Raul Pardo, Nicolas Bourg, Sylvie Souquere, Céline Mayet, Gérard Pierron, Sandrine Lévêque-Fort, Juan Botas, Sandrine Humbert and Frédéric Saudou

    Version of Record online : 14 JUL 2015, DOI: 10.15252/embj.201490808