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There are 5196 results for: content related to: The neurobiology of amyotrophic lateral sclerosis

  1. You have full text access to this OnlineOpen article
    Review: Prion-like mechanisms of transactive response DNA binding protein of 43 kDa (TDP-43) in amyotrophic lateral sclerosis (ALS)

    Neuropathology and Applied Neurobiology

    Volume 41, Issue 5, August 2015, Pages: 578–597, Phillip Smethurst, Katie Claire Louise Sidle and John Hardy

    Version of Record online : 20 APR 2015, DOI: 10.1111/nan.12206

  2. Rodent Models of Amyotrophic Lateral Sclerosis

    Unit

    Current Protocols in Pharmacology

    5:5.67.1–5.67.21

    Thomas Philips and Jeffrey D. Rothstein

    Published Online : 1 JUN 2015, DOI: 10.1002/0471141755.ph0567s69

  3. Genetic strategies to study TDP-43 in rodents and to develop preclinical therapeutics for amyotrophic lateral sclerosis

    European Journal of Neuroscience

    Volume 34, Issue 8, October 2011, Pages: 1179–1188, David B. Wang, Michael A. Gitcho, Brian C. Kraemer and Ronald L. Klein

    Version of Record online : 21 JUL 2011, DOI: 10.1111/j.1460-9568.2011.07803.x

  4. Review: Transactive response DNA-binding protein 43 (TDP-43): mechanisms of neurodegeneration

    Neuropathology and Applied Neurobiology

    Volume 36, Issue 2, April 2010, Pages: 97–112, T. F. Gendron, K. A. Josephs and L. Petrucelli

    Version of Record online : 23 MAR 2010, DOI: 10.1111/j.1365-2990.2010.01060.x

  5. Ubiquitinated, p62 immunopositive cerebellar cortical neuronal inclusions are evident across the spectrum of TDP-43 proteinopathies but are only rarely additionally immunopositive for phosphorylation-dependent TDP-43

    Neuropathology

    Volume 31, Issue 3, June 2011, Pages: 239–249, Andrew King, Satomi Maekawa, Istvan Bodi, Claire Troakes and Safa Al-Sarraj

    Version of Record online : 1 DEC 2010, DOI: 10.1111/j.1440-1789.2010.01171.x

  6. You have free access to this content
    TDP-43: the relationship between protein aggregation and neurodegeneration in amyotrophic lateral sclerosis and frontotemporal lobar degeneration

    The FEBS Journal

    Volume 278, Issue 19, October 2011, Pages: 3539–3549, Robert H. Baloh

    Version of Record online : 24 AUG 2011, DOI: 10.1111/j.1742-4658.2011.08256.x

  7. Phosphorylated and cleaved TDP-43 in ALS, FTLD and other neurodegenerative disorders and in cellular models of TDP-43 proteinopathy

    Neuropathology

    Volume 30, Issue 2, April 2010, Pages: 170–181, Tetsuaki Arai, Masato Hasegawa, Takashi Nonoka, Fuyuki Kametani, Makiko Yamashita, Masato Hosokawa, Kazuhiro Niizato, Kuniaki Tsuchiya, Zen Kobayashi, Kenji Ikeda, Mari Yoshida, Mitsumoto Onaya, Hiroshige Fujishiro and Haruhiko Akiyama

    Version of Record online : 19 JAN 2010, DOI: 10.1111/j.1440-1789.2009.01089.x

  8. Amyotrophic lateral sclerosis and frontotemporal lobar degeneration: A spectrum of TDP-43 proteinopathies

    Neuropathology

    Volume 30, Issue 2, April 2010, Pages: 103–112, Felix Geser, Virginia M.-Y. Lee and John Q. Trojanowski

    Version of Record online : 20 JAN 2010, DOI: 10.1111/j.1440-1789.2009.01091.x

  9. RNA-binding proteins in neurodegenerative disease: TDP-43 and beyond

    Wiley Interdisciplinary Reviews: RNA

    Volume 3, Issue 2, March/April 2012, Pages: 265–285, Keith A. Hanson, Sang Hwa Kim and Randal S. Tibbetts

    Version of Record online : 25 OCT 2011, DOI: 10.1002/wrna.111

  10. You have free access to this content
    TDP-43 and FUS/TLS: cellular functions and implications for neurodegeneration

    The FEBS Journal

    Volume 278, Issue 19, October 2011, Pages: 3550–3568, Fabienne C. Fiesel and Philipp J. Kahle

    Version of Record online : 24 AUG 2011, DOI: 10.1111/j.1742-4658.2011.08258.x

  11. You have free access to this content
    Stress granules in neurodegeneration – lessons learnt from TAR DNA binding protein of 43 kDa and fused in sarcoma

    The FEBS Journal

    Volume 280, Issue 18, September 2013, Pages: 4348–4370, Eva Bentmann, Christian Haass and Dorothee Dormann

    Version of Record online : 9 MAY 2013, DOI: 10.1111/febs.12287

  12. You have free access to this content
    Significance and limitation of the pathological classification of TDP-43 proteinopathy

    Neuropathology

    Volume 34, Issue 6, December 2014, Pages: 578–588, Tetsuaki Arai

    Version of Record online : 8 SEP 2014, DOI: 10.1111/neup.12138

  13. You have free access to this content
    Physiological functions and pathobiology of TDP-43 and FUS/TLS proteins

    Journal of Neurochemistry

    Volume 138, Issue S1, August 2016, Pages: 95–111, Antonia Ratti and Emanuele Buratti

    Version of Record online : 15 JUN 2016, DOI: 10.1111/jnc.13625

  14. Detection of TDP-43 oligomers in frontotemporal lobar degeneration–TDP

    Annals of Neurology

    Volume 78, Issue 2, August 2015, Pages: 211–221, Patricia F. Kao, Yun-Ru Chen, Xiao-Bo Liu, Charles DeCarli, William W. Seeley and Lee-Way Jin

    Version of Record online : 30 JUN 2015, DOI: 10.1002/ana.24431

  15. You have full text access to this OnlineOpen article
    Spliceosome integrity is defective in the motor neuron diseases ALS and SMA

    EMBO Molecular Medicine

    Volume 5, Issue 2, February 2013, Pages: 221–234, Hitomi Tsuiji, Yohei Iguchi, Asako Furuya, Ayane Kataoka, Hiroyuki Hatsuta, Naoki Atsuta, Fumiaki Tanaka, Yoshio Hashizume, Hiroyasu Akatsu, Shigeo Murayama, Gen Sobue and Koji Yamanaka

    Version of Record online : 25 JAN 2013, DOI: 10.1002/emmm.201202303

  16. RNA quality control and protein aggregates in amyotrophic lateral sclerosis: A review

    Muscle & Nerve

    Volume 47, Issue 3, March 2013, Pages: 330–338, Ashok Verma and Rup Tandan

    Version of Record online : 4 FEB 2013, DOI: 10.1002/mus.23673

  17. TARDBP and FUS Mutations Associated with Amyotrophic Lateral Sclerosis: Summary and Update

    Human Mutation

    Volume 34, Issue 6, June 2013, Pages: 812–826, Serena Lattante, Guy A. Rouleau and Edor Kabashi

    Version of Record online : 29 APR 2013, DOI: 10.1002/humu.22319

  18. You have free access to this content
    What is the key player in TDP-43 pathology in ALS: Disappearance from the nucleus or inclusion formation in the cytoplasm?

    Neurology and Clinical Neuroscience

    Volume 1, Issue 1, January 2013, Pages: 11–17, Osamu Onodera, Akihiro Sugai, Takuya Konno, Mari Tada, Akihide Koyama and Masatoyo Nishizawa

    Version of Record online : 31 JAN 2013, DOI: 10.1002/ncn3.9

  19. You have free access to this content
    Redox signalling directly regulates TDP-43 via cysteine oxidation and disulphide cross-linking

    The EMBO Journal

    Volume 31, Issue 5, March 7, 2012, Pages: 1241–1252, Todd J Cohen, Andrew W Hwang, Travis Unger, John Q Trojanowski and Virginia M Y Lee

    Version of Record online : 23 DEC 2011, DOI: 10.1038/emboj.2011.471

  20. p62/sequestosome 1 binds to TDP-43 in brains with frontotemporal lobar degeneration with TDP-43 inclusions

    Journal of Neuroscience Research

    Volume 90, Issue 10, October 2012, Pages: 2034–2042, Kunikazu Tanji, Hai-Xin Zhang, Fumiaki Mori, Akiyoshi Kakita, Hitoshi Takahashi and Koichi Wakabayashi

    Version of Record online : 5 JUN 2012, DOI: 10.1002/jnr.23081