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There are 9812 results for: content related to: Desperately seeking cancer drugs: explaining the emergence and outcomes of accelerated pharmaceutical regulation

  1. You have full text access to this OnlineOpen article
    Iressa induces cytostasis and augments Fas-mediated apoptosis in acinic cell adenocarcinoma overexpressing HER2/neu

    International Journal of Cancer

    Volume 119, Issue 2, 15 July 2006, Pages: 441–454, Marie P. Piechocki, George H. Yoo, Susan K. Dibbley, Esmael H. Amjad and Fulvio Lonardo

    Article first published online : 9 FEB 2006, DOI: 10.1002/ijc.21837

  2. “Combi-targeting” mitozolomide: Conferring novel signaling inhibitory properties to an abandoned DNA alkylating agent in the treatment of advanced prostate cancer

    The Prostate

    Volume 72, Issue 12, 1 September 2012, Pages: 1273–1285, Youqiang Fang, Qiyu Qiu, Juozas Domarkas, Anne-Laure Larroque-Lombard, Suman Rao, Zakaria Rachid, Bernard F. Gibbs, Xin Gao and Bertrand J. Jean-Claude

    Article first published online : 30 JAN 2012, DOI: 10.1002/pros.22475

  3. VEGF inhibitor (Iressa) arrests histone deacetylase expression: Single-cell cotransfection imaging cytometry for multi-target-multi-drug analysis

    Journal of Cellular Physiology

    Volume 226, Issue 8, August 2011, Pages: 2115–2122, Yu Kyung Tak, Pravin K. Naoghare, Eunyoung Han and Joon Myong Song

    Article first published online : 25 APR 2011, DOI: 10.1002/jcp.22540

  4. Iressa strengthens the cytotoxic effect of docetaxel in NSCLC models that harbor specific molecular characteristics

    Journal of Cellular Physiology

    Volume 212, Issue 3, September 2007, Pages: 710–716, Marco Rosetti, Wainer Zoli, Anna Tesei, Paola Ulivi, Francesco Fabbri, Ivan Vannini, Giovanni Brigliadori, Anna Maria Granato, Dino Amadori and Rosella Silvestrini

    Article first published online : 25 APR 2007, DOI: 10.1002/jcp.21067

  5. You have full text access to this OnlineOpen article
    Mutation of epidermal growth factor receptor is associated with MIG6 expression

    FEBS Journal

    Volume 276, Issue 18, September 2009, Pages: 5239–5251, Takeshi Nagashima, Ryoko Ushikoshi-Nakayama, Atsushi Suenaga, Kaori Ide, Noriko Yumoto, Yoshimi Naruo, Kaoru Takahashi, Yuko Saeki, Makoto Taiji, Hiroshi Tanaka, Shih-Feng Tsai and Mariko Hatakeyama

    Article first published online : 10 AUG 2009, DOI: 10.1111/j.1742-4658.2009.07220.x

  6. A 2,6-Disubstituted 4-Anilinoquinazoline Derivative Facilitates Cardiomyogenesis of Embryonic Stem Cells

    ChemMedChem

    Volume 7, Issue 4, April 2012, Pages: 733–740, Guofang Shen, Ying Hu, Jianwei Wu, Ke Jin, Danyan Zhu, Yandong Zhang, Prof. Dr. Yongping Yu and Prof. Dr. Yijia Lou

    Article first published online : 2 FEB 2012, DOI: 10.1002/cmdc.201100603

  7. Blockade of sonic hedgehog signal pathway enhances antiproliferative effect of EGFR inhibitor in pancreatic cancer cells

    Acta Pharmacologica Sinica

    Volume 28, Issue 8, August 2007, Pages: 1224–1230, Wei-guo HU, Tao LIU, Jiong-xin XIONG and Chun-you WANG

    Article first published online : 31 JUL 2007, DOI: 10.1111/j.1745-7254.2007.00620.x

  8. You have full text access to this OnlineOpen article
    Insulin-induced proliferation of bladder cancer cells is mediated through activation of the epidermal growth factor system

    FEBS Journal

    Volume 273, Issue 23, December 2006, Pages: 5479–5489, Dorthe Ornskov, Ebba Nexo and Boe S. Sorensen

    Article first published online : 3 NOV 2006, DOI: 10.1111/j.1742-4658.2006.05539.x

  9. Tyrosine kinase inhibitors in endometrial cancer

    International Journal of Gynecological Cancer

    Volume 15, Issue 2, March 2005, Pages: 409–411, K.K. Leslie, L. Laidler, L. Albitar, S. Davies, A. Holmes, T. Nguyen, J. Bolnick and D. Dai

    Article first published online : 18 MAR 2005, DOI: 10.1111/j.1525-1438.2005.abst_20.x

  10. EGFR Regulates the Side Population in Head and Neck Squamous Cell Carcinoma

    The Laryngoscope

    Volume 116, Issue 3, March 2006, Pages: 401–406, Jocelyn S. Chen, Francisco S. Pardo, Jessica Wang-Rodriguez, Theresa S. Chu, Jay Patrick Lopez, Joseph Aguilera, Xabier Altuna, Robert A. Weisman and Weg M. Ongkeko

    Article first published online : 2 JAN 2009, DOI: 10.1097/01.mlg.0000195075.14093.fb

  11. Phosphoproteomics identified Endofin, DCBLD2, and KIAA0582 as novel tyrosine phosphorylation targets of EGF signaling and Iressa in human cancer cells

    PROTEOMICS

    Volume 7, Issue 14, No. 14 July 2007, Pages: 2384–2397, Yunhao Chen, Teck-Yew Low, Lee-Yee Choong, Rajarshi Sankar Ray, Yee-Ling Tan, Weiyi Toy, Qingsong Lin, Boon Keong Ang, Chee Hong Wong, Simin Lim, Bin Li, Choy-Leong Hew, Newman Siu-Kwan Sze, Brian J. Druker and Yoon-Pin Lim

    Article first published online : 14 JUN 2007, DOI: 10.1002/pmic.200600968

  12. Protein-tyrosine Kinase Inhibitors

    Contemporary Drug Synthesis

    Jie Jack Li, Douglas S. Johnson, Drago R. Sliskovic, Bruce D. Roth, Pages: 29–38, 2004

    Published Online : 11 NOV 2004, DOI: 10.1002/0471686743.ch4

  13. Derivatives of Iressa, a Specific Epidermal Growth Factor Receptor Inhibitor, are Powerful Apoptosis Inducers in PC3 Prostatic Cancer Cells

    ChemMedChem

    Volume 2, Issue 3, March 12, 2007, Pages: 318–332, Aurélie Telliez, Matthieu Desroses, Nicole Pommery, Olivier Briand, Amaury Farce, Guillaume Laconde, Amélie Lemoine, Patrick Depreux and Jean-Pierre Hénichart

    Article first published online : 8 JAN 2007, DOI: 10.1002/cmdc.200600128

  14. You have open access to this content
    Direct inhibition of EGF receptor activation in vascular endothelial cells by gefitinib (‘Iressa’, ZD1839)

    Cancer Science

    Volume 95, Issue 7, July 2004, Pages: 614–618, Akira Hirata, Hisanori Uehara, Keisuke Izumi, Seiji Naito, Michihiko Kuwano and Mayumi Ono

    Article first published online : 19 AUG 2005, DOI: 10.1111/j.1349-7006.2004.tb02496.x

  15. Fluorine-18 labeling of 6,7-disubstituted anilinoquinazoline derivatives for positron emission tomography (PET) imaging of tyrosine kinase receptors: synthesis of 18F-Iressa and related molecular probes

    Journal of Labelled Compounds and Radiopharmaceuticals

    Volume 48, Issue 11, 15 October 2005, Pages: 829–843, Yann Seimbille, Michael E. Phelps, Johannes Czernin and Daniel H. S. Silverman

    Article first published online : 2 SEP 2005, DOI: 10.1002/jlcr.998

  16. Pharmacodynamic Assays in Cancer Drug Discovery: From Preclinical Validation to Clinical Trial Monitoring

    Molecular Cancer Therapeutics: Strategies for Drug Discovery and Development

    Robert B. Lobell, Nancy E. Kohl, Laura Sepp-Lorenzino, Pages: 227–254, 2005

    Published Online : 28 JAN 2005, DOI: 10.1002/047165616X.ch11

  17. You have free access to this content
    Appendix : Case Histories

    Pharmaceutical Lifecycle Management: Making the Most of Each and Every Brand

    Tony Ellery, Neal Hansen, Pages: 294–370, 2012

    Published Online : 8 MAY 2012, DOI: 10.1002/9781118266755.app1

  18. Follicular and epidermal alterations in patients treated with ZD1839 (Iressa), an inhibitor of the epidermal growth factor receptor

    British Journal of Dermatology

    Volume 147, Issue 3, September 2002, Pages: 598–601, R. Van Doorn, G. Kirtschig, E. Scheffer, T.J. Stoof and G. Giaccone

    Article first published online : 5 SEP 2002, DOI: 10.1046/j.1365-2133.2002.04864.x

  19. You have open access to this content
    A report of two bronchioloalveolar carcinoma cases which were rapidly improved by treatment with the epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 (“Iressa”

    Cancer Science

    Volume 94, Issue 5, May 2003, Pages: 453–458, Seiji Yano, Takanori Kanematsu, Toyokazu Miki, Yoshinori Aono, Masahiko Azuma, Akihiko Yamamoto, Hisanori Uehara and Saburo Sone

    Article first published online : 19 AUG 2005, DOI: 10.1111/j.1349-7006.2003.tb01464.x

  20. Modulation of Epidermal Growth Factor Receptor in Endocrine-Resistant, Estrogen-Receptor-Positive Breast Cancer

    Annals of the New York Academy of Sciences

    Volume 963, Issue 1, June 2002, Pages: 104–115, R. I. NICHOLSON, I. R. HUTCHESON, M. E. HARPER, J. M. KNOWLDEN, D. BARROW, R. A. McCLELLAND, H. E. JONES, A. E. WAKELING and J.M. W. GEE

    Article first published online : 24 JAN 2006, DOI: 10.1111/j.1749-6632.2002.tb04101.x