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There are 1713154 results for: content related to: LRRK2 Gly2385Arg variant is a risk factor of Parkinson’s disease among Han-Chinese from mainland China

  1. Deep sequencing of the LRRK2 gene in 14,002 individuals reveals evidence of purifying selection and independent origin of the p.Arg1628Pro mutation in Europe

    Human Mutation

    Volume 33, Issue 7, July 2012, Pages: 1087–1098, Justin P. Rubio, Simon Topp, Liling Warren, Pamela L. St. Jean, Daniel Wegmann, Darren Kessner, John Novembre, Judong Shen, Dana Fraser, Jennifer Aponte, Keith Nangle, Lon R. Cardon, Margaret G. Ehm, Stephanie L. Chissoe, John C. Whittaker, Matthew R. Nelson and Vincent E. Mooser

    Article first published online : 4 APR 2012, DOI: 10.1002/humu.22075

  2. You have free access to this content
    LRRK2 gene variation and its contribution to Parkinson disease

    Human Mutation

    Volume 30, Issue 8, August 2009, Pages: 1153–1160, Coro Paisán-Ruiz

    Article first published online : 21 APR 2009, DOI: 10.1002/humu.21038

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    LRRK2 in Parkinson’s disease: genetic and clinical studies from patients

    FEBS Journal

    Volume 276, Issue 22, November 2009, Pages: 6455–6463, Udhaya Kumari and E. K. Tan

    Article first published online : 5 OCT 2009, DOI: 10.1111/j.1742-4658.2009.07344.x

  4. LRRK2 mutations and risk variants in Japanese patients with Parkinson's disease

    Movement Disorders

    Volume 24, Issue 7, 15 May 2009, Pages: 1034–1041, Cyrus P. Zabetian, Mitsutoshi Yamamoto, Alexis N. Lopez, Hiroshi Ujike, Ignacio F. Mata, Yuishin Izumi, Ryuji Kaji, Hirofumi Maruyama, Hiroyuki Morino, Masaya Oda, Carolyn M. Hutter, Karen L. Edwards, Gerard D. Schellenberg, Debby W. Tsuang, Dora Yearout, Eric B. Larson and Hideshi Kawakami

    Article first published online : 2 APR 2009, DOI: 10.1002/mds.22514

  5. The prevalence of LRRK2 Gly2385Arg variant in Chinese Han population with Parkinson's disease

    Movement Disorders

    Volume 22, Issue 16, 15 December 2007, Pages: 2439–2443, Li Cao, Ting Zhang, Qin Xiao, Ying Wang, Li Bai, Guo Qiang Lu, Jian Fang Ma, Jing Zhang, Jian Qing Ding and Sheng Di Chen

    Article first published online : 25 OCT 2007, DOI: 10.1002/mds.21763

  6. Abstracts of The Movement Disorder Society's Twelfth International Congress of Parkinson's Disease and Movement Disorders

    Movement Disorders

    Volume 23, Issue S1, 15 May 2008, Pages: S1–S422,

    Article first published online : 28 MAY 2008, DOI: 10.1002/mds.22133

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    Poster Presentations

    Movement Disorders

    Volume 27, Issue S1, June 2012, Pages: S1–S523,

    Article first published online : 19 JUN 2012, DOI: 10.1002/mds.25051

  8. Prediction of the Repeat Domain Structures and Impact of Parkinsonism-Associated Variations on Structure and Function of all Functional Domains of Leucine-Rich Repeat Kinase 2 (LRRK2)

    Human Mutation

    Volume 35, Issue 4, April 2014, Pages: 395–412, Ryan D. Mills, Terrence D. Mulhern, Fei Liu, Janetta G. Culvenor and Heung-Chin Cheng

    Article first published online : 24 FEB 2014, DOI: 10.1002/humu.22515

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    Leucine-rich repeat kinase 2 (LRRK2): A key player in the pathogenesis of Parkinson's disease

    Journal of Neuroscience Research

    Volume 87, Issue 6, 1 May 2009, Pages: 1283–1295, Payal N. Gandhi, Shu G. Chen and Amy L. Wilson-Delfosse

    Article first published online : 21 NOV 2008, DOI: 10.1002/jnr.21949

  10. Molecular biology changes associated with LRRK2 mutations in Parkinson's disease

    Journal of Neuroscience Research

    Volume 86, Issue 9, July 2008, Pages: 1895–1901, Yi Wei Lu and Eng-King Tan

    Article first published online : 13 MAR 2008, DOI: 10.1002/jnr.21656

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    Leucine-rich repeat kinase 2 disturbs mitochondrial dynamics via Dynamin-like protein

    Journal of Neurochemistry

    Volume 122, Issue 3, August 2012, Pages: 650–658, Jingwen Niu, Mei Yu, Chunyan Wang and Zhiheng Xu

    Article first published online : 22 JUN 2012, DOI: 10.1111/j.1471-4159.2012.07809.x

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    Homo- and heterodimerization of ROCO kinases: LRRK2 kinase inhibition by the LRRK2 ROCO fragment

    Journal of Neurochemistry

    Volume 111, Issue 3, November 2009, Pages: 703–715, Christian L. Klein, Giorgio Rovelli, Wolfdieter Springer, Christoph Schall, Thomas Gasser and Philipp J. Kahle

    Article first published online : 27 AUG 2009, DOI: 10.1111/j.1471-4159.2009.06358.x

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    Investigation of leucine-rich repeat kinase 2

    FEBS Journal

    Volume 276, Issue 2, January 2009, Pages: 466–478, Vasanti S. Anand, Laurie J. Reichling, Kerri Lipinski, Wayne Stochaj, Weili Duan, Kerry Kelleher, Pooja Pungaliya, Eugene L. Brown, Peter H. Reinhart, Richard Somberg, Warren D. Hirst, Steven M. Riddle and Steven P. Braithwaite

    Article first published online : 8 DEC 2008, DOI: 10.1111/j.1742-4658.2008.06789.x

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    Poster Presentations

    Movement Disorders

    Volume 29, Issue S1, May 2014, Pages: S1–S571,

    Article first published online : 6 JUN 2014, DOI: 10.1002/mds.25914

  15. A Korean Parkinson's disease family with the LRRK2 p.Tyr1699Cys mutation showing clinical heterogeneity

    Movement Disorders

    Volume 27, Issue 2, February 2012, Pages: 320–324, Ji Sun Kim, Jin Whan Cho, Hyeeun Shin, Won Yong Lee, Chang-Seok Ki, Ah Ra Cho and Hee-Tae Kim

    Article first published online : 9 DEC 2011, DOI: 10.1002/mds.24033

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    Abstracts of The Movement Disorder Society's Eleventh International Congress of Parkinson's Disease and Movement Disorders

    Movement Disorders

    Volume 22, Issue S16, 2007, Pages: S1–S325,

    Article first published online : 24 APR 2007, DOI: 10.1002/mds.21535

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    LRRK2 in Parkinson’s disease: function in cells and neurodegeneration

    FEBS Journal

    Volume 276, Issue 22, November 2009, Pages: 6436–6444, Philip J. Webber and Andrew B. West

    Article first published online : 5 OCT 2009, DOI: 10.1111/j.1742-4658.2009.07342.x

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    LRRK2 in Parkinson’s disease: in vivo models and approaches for understanding pathogenic roles

    FEBS Journal

    Volume 276, Issue 22, November 2009, Pages: 6445–6454, Zhenyu Yue

    Article first published online : 5 OCT 2009, DOI: 10.1111/j.1742-4658.2009.07343.x

  19. Analysis of LRRK2 Gly2385Arg genetic variant in non-Chinese Asians

    Movement Disorders

    Volume 22, Issue 12, 15 September 2007, Pages: 1816–1818, Eng-King Tan, Yi Zhao, Louis Tan, Hui-Qin Lim, Jasinda Lee, Yih Yuen, Ratnagopal Pavanni, Meng-Cheong Wong, Stephanie Fook-Chong and Jian-Jun Liu

    Article first published online : 20 JUL 2007, DOI: 10.1002/mds.21658

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    Phosphorylation of LRRK2 serines 955 and 973 is disrupted by Parkinson’s disease mutations and LRRK2 pharmacological inhibition

    Journal of Neurochemistry

    Volume 120, Issue 1, January 2012, Pages: 37–45, Elizabeth A. Doggett, Jing Zhao, Christina N. Mork, Dongmei Hu and R. Jeremy Nichols

    Article first published online : 11 NOV 2011, DOI: 10.1111/j.1471-4159.2011.07537.x