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There are 9225 results for: content related to: Prevalence of Clinically Relevant UGT1A Alleles and Haplotypes in African Populations

  1. UDP-Glucuronosyltransferases

    Metabolism of Drugs and Other Xenobiotics

    Christian P. Strassburg, Sandra Kalthoff, Pages: 67–116, 2012

    Published Online : 4 JUN 2012, DOI: 10.1002/9783527630905.ch3

  2. Restriction fragment length polymorphism effectively identifies exon 1 mutation of UGT1A1 gene in patients with Gilbert's Syndrome

    Liver International

    Volume 35, Issue 8, August 2015, Pages: 2050–2056, Tzu-Yue Shiu, Hsin-Hung Huang, Hsuan-Hwai Lin, Yu-Lueng Shih, Heng-Cheng Chu, Wei-Kuo Chang and Tsai-Yuan Hsieh

    Version of Record online : 6 FEB 2015, DOI: 10.1111/liv.12785

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    Spectrum of UGT1A1 mutations in Crigler-Najjar (CN) syndrome patients: identification of twelve novel alleles and genotype-phenotype correlation

    Human Mutation

    Volume 25, Issue 3, March 2005, Page: 325, Veronica Servedio, Maria d'Apolito, Nunzia Maiorano, Barbara Minuti, Francesca Torricelli, Flavio Ronchi, Lucia Zancan, Silverio Perrotta, Pietro Vajro, Loredana Boschetto and Achille Iolascon

    Version of Record online : 14 FEB 2005, DOI: 10.1002/humu.9322

  4. Combined UGT1A1 and UGT1A7 variant alleles are associated with increased risk of Gilbert’s syndrome in Taiwanese adults

    Clinical Genetics

    Volume 72, Issue 4, October 2007, Pages: 321–328, H-C Teng, M-J Huang, K-S Tang, S-S Yang, C-S Tseng and C-S Huang

    Version of Record online : 6 AUG 2007, DOI: 10.1111/j.1399-0004.2007.00873.x

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    Effect of UGT1A1, UGT1A3, DIO1 and DIO2 polymorphisms on L-thyroxine doses required for TSH suppression in patients with differentiated thyroid cancer

    British Journal of Clinical Pharmacology

    Volume 78, Issue 5, November 2014, Pages: 1067–1075, Ana B. Santoro, Daniela D. Vargens, Mateus de Camargo Barros Filho, Daniel A. Bulzico, Luiz Paulo Kowalski, Ricardo M. R. Meirelles, Daniela P. Paula, Ronaldo R. S. Neves, Cencita N. Pessoa, Claudio J. Struchine and Guilherme Suarez-Kurtz

    Version of Record online : 20 OCT 2014, DOI: 10.1111/bcp.12437

  6. Phenotype-genotype correlation of in vitro SN-38 (active metabolite of irinotecan) and bilirubin glucuronidation in human liver tissue with UGT1A1 promoter polymorphism

    Clinical Pharmacology & Therapeutics

    Volume 65, Issue 5, May 1999, Pages: 576–582, Lalitha Iyer, Diana Hall, Soma Das, Melissa A. Mortell, Jacqueline Ramírez, Sarang Kim, Anna Di Rienzo and Mark J. Ratain

    Version of Record online : 13 MAY 1999, DOI: 10.1016/S0009-9236(99)70078-0

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    Gilbert syndrome redefined: A complex genetic haplotype influences the regulation of glucuronidation


    Volume 55, Issue 6, June 2012, Pages: 1912–1921, Ursula Ehmer, Sandra Kalthoff, Bastian Fakundiny, Brigitte Pabst, Nicole Freiberg, Ronald Naumann, Michael P. Manns and Christian P. Strassburg

    Version of Record online : 23 APR 2012, DOI: 10.1002/hep.25561

  8. Combined effect of genetic polymorphisms in phase I and II biotransformation enzymes on head and neck cancer risk

    Head & Neck

    Volume 35, Issue 6, June 2013, Pages: 858–867, Martin Lacko, Adri C. Voogd, Hennie M. J. Roelofs, Rene H. M. te Morsche, Michel B. Oude Ophuis, Wilbert H. M. Peters and Johannes J. Manni

    Version of Record online : 19 JUN 2012, DOI: 10.1002/hed.23054

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    UGT1A1 genotype and irinotecan therapy: general review and implementation in routine practice

    Fundamental & Clinical Pharmacology

    Volume 29, Issue 3, June 2015, Pages: 219–237, Marie-Christine Etienne-Grimaldi, Jean-Christophe Boyer, Fabienne Thomas, Sylvie Quaranta, Nicolas Picard, Marie-Anne Loriot, Céline Narjoz, Delphine Poncet, Marie-Claude Gagnieu, Cécile Ged, Franck Broly, Valérie Le Morvan, Régis Bouquié, Marie-Pierre Gaub, Laurent Philibert, François Ghiringhelli, Chantal Le Guellec and Collective work by the Groupe de Pharmacologie Clinique Oncologique (GPCO-Unicancer) and the French Réseau National de Pharmacogénétique Hospitalière (RNPGx)

    Version of Record online : 4 MAY 2015, DOI: 10.1111/fcp.12117

  10. You have full text access to this OnlineOpen article
    Rapid and sensitive detection of UGT1A1 polymorphisms associated with irinotecan toxicity by a novel DNA microarray

    Cancer Science

    Volume 108, Issue 7, July 2017, Pages: 1504–1509, Ryouichi Tsunedomi, Shoichi Hazama, Naoko Okayama, Masaaki Oka and Hiroaki Nagano

    Version of Record online : 5 JUN 2017, DOI: 10.1111/cas.13272

  11. Pharmacogenetic Testing for Uridine Diphosphate Glucuronosyltransferase 1A1 Polymorphisms: Are We There Yet?

    Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy

    Volume 28, Issue 6, June 2008, Pages: 755–768, Dr. Minoli A. Perera, Dr. Federico Innocenti and Dr. Mark J. Ratain

    Version of Record online : 6 JAN 2012, DOI: 10.1592/phco.28.6.755

  12. Association of neonatal hyperbilirubinemia with uridine diphosphate-glucuronosyltransferase 1A1 gene polymorphisms: Meta-analysis

    Pediatrics International

    Volume 53, Issue 4, August 2011, Pages: 530–540, Jun Long, Shaofang Zhang, Xiaoyan Fang, Yuyuan Luo and Jiebo Liu

    Version of Record online : 18 AUG 2011, DOI: 10.1111/j.1442-200X.2011.03337.x

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    Limited influence of UGT1A1*28 and no effect of UGT2B7*2 polymorphisms on UGT1A1 or UGT2B7 activities and protein expression in human liver microsomes

    British Journal of Clinical Pharmacology

    Volume 64, Issue 4, October 2007, Pages: 458–468, Vincent C. Peterkin, Jonathan N. Bauman, Theunis C. Goosen, Lee Menning, Michael Z. Man, Joseph D. Paulauskis, J. Andrew Williams and Scott P. Myrand

    Version of Record online : 6 JUN 2007, DOI: 10.1111/j.1365-2125.2007.02923.x

  14. UDP-Glucuronosyltransferase (UGT) Polymorphisms Affect Atorvastatin Lactonization In Vitro and In Vivo

    Clinical Pharmacology & Therapeutics

    Volume 87, Issue 1, January 2010, Pages: 65–73, S Riedmaier, K Klein, U Hofmann, J E Keskitalo, P J Neuvonen, M Schwab, M Niemi and U M Zanger

    Version of Record online : 30 SEP 2009, DOI: 10.1038/clpt.2009.181

  15. You have full text access to this OnlineOpen article
    Pregnane-x-receptor controls hepatic glucuronidation during pregnancy and neonatal development in humanized UGT1 mice


    Volume 56, Issue 2, August 2012, Pages: 658–667, Shujuan Chen, Mei-Fei Yueh, Ronald M. Evans and Robert H. Tukey

    Version of Record online : 11 JUN 2012, DOI: 10.1002/hep.25671

  16. Oncology Drug Dosing in Gilbert Syndrome Associated with UGT1A1: A Summary of the Literature

    Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy

    Volume 37, Issue 8, August 2017, Pages: 956–972, Vincent H. Ha, Jennifer Jupp and Roger Y. Tsang

    Version of Record online : 28 JUN 2017, DOI: 10.1002/phar.1946

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    UGT1A1*6,1A7*3, and 1A9*22 genotypes predict severe neutropenia in FOLFIRI-treated metastatic colorectal cancer in two prospective studies in Japan

    Cancer Science

    Volume 104, Issue 12, December 2013, Pages: 1662–1669, Shoichi Hazama, Hideyuki Mishima, Ryouichi Tsunedomi, Yusuke Okuyama, Takeshi Kato, Ken-ichi Takahashi, Hiroshi Nozawa, Hideaki Ando, Michiya Kobayashi, Hiroyoshi Takemoto, Naoki Nagata, Shinsuke Kanekiyo, Yuka Inoue, Yoshihiko Hamamoto, Yusuke Fujita, Yuji Hinoda, Naoko Okayama, Koji Oba, Jun-ichi Sakamoto and Masaaki Oka

    Version of Record online : 27 OCT 2013, DOI: 10.1111/cas.12283

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    Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for UGT1A1 and Atazanavir Prescribing

    Clinical Pharmacology & Therapeutics

    Volume 99, Issue 4, April 2016, Pages: 363–369, RS Gammal, MH Court, CE Haidar, OF Iwuchukwu, AH Gaur, M Alvarellos, C Guillemette, JL Lennox, M Whirl-Carrillo, SS Brummel, MJ Ratain, TE Klein, BR Schackman, KE Caudle and DW Haas

    Version of Record online : 9 NOV 2015, DOI: 10.1002/cpt.269

  19. UDP-Glucuronosyltransferases: Pharmacogenetics, Functional Characterization, and Clinical Relevance

    Standard Article

    Encyclopedia of Drug Metabolism and Interactions

    Robert S. Foti and Michael B. Fisher

    Published Online : 31 JAN 2012, DOI: 10.1002/9780470921920.edm015

  20. Influence of Genetic Variants in UGT1A1 and UGT1A9 on the In Vivo Glucuronidation of SN-38

    The Journal of Clinical Pharmacology

    Volume 44, Issue 8, August 2004, Pages: 854–860, Dr Luca Paoluzzi, Mr Arun S. Singh, Dr Douglas K. Price, Dr Romano Danesi, Dr Ron H. J. Mathijssen, Dr Jaap Verweij, Dr William D. Figg and Dr Alex Sparreboom

    Version of Record online : 8 MAR 2013, DOI: 10.1177/0091270004267159