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There are 8066420 results for: content related to: Can we trust the results of trials that are stopped early?

  1. Quantifying the bias in the estimated treatment effect in randomized trials having interim analyses and a rule for early stopping for futility

    Statistics in Medicine

    Volume 36, Issue 9, 30 April 2017, Pages: 1506–1518, S. D. Walter, H. Han, M. Briel and G. H. Guyatt

    Version of Record online : 9 FEB 2017, DOI: 10.1002/sim.7242

  2. You have free access to this content
    Evidence-based urology in practice: randomized controlled trials stopped early for benefit

    BJU International

    Volume 106, Issue 7, October 2010, Pages: 962–963, Steven E. Canfield, Shahnaz Sultan and Philipp Dahm

    Version of Record online : 12 AUG 2010, DOI: 10.1111/j.1464-410X.2010.09542.x

  3. Data monitoring and interim analyses in the pharmaceutical industry: Ethical and logistical considerations

    Statistics in Medicine

    Volume 12, Issue 5-6, March 1993, Pages: 471–479, Frank W. Rockhold and Gregory G. Enas

    Version of Record online : 12 OCT 2006, DOI: 10.1002/sim.4780120512

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    Planning and monitoring of placebo-controlled survival trials: comparison of the triangular test with usual interim analyses methods

    British Journal of Clinical Pharmacology

    Volume 55, Issue 3, March 2003, Pages: 299–306, Jean-Sébastien Hulot, Michel Cucherat, Andrew Charlesworth, Dirk J. Van Veldhuisen, Jean-Christophe Corvol, Alain Mallet, Jean-Pierre Boissel, John Hampton and Philippe Lechat

    Version of Record online : 10 MAR 2003, DOI: 10.1046/j.1365-2125.2003.01768.x

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    Screening, endpoint classification, and safety monitoring in the Metoprolol CR/XL Randomised Intervention Trial in Congestive Heart Failure (MERIT-HF)

    European Journal of Heart Failure

    Volume 2, Issue 3, September 2000, Pages: 315–324, Björn Fagerberg

    Version of Record online : 3 SEP 2001, DOI: 10.1016/S1388-9842(00)00101-X

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    Interim analyses in clinical trials

    British Journal of Clinical Pharmacology

    Volume 51, Issue 5, May 2001, Page: 393, John Whitehead, Susan Todd, Anne Whitehead and Nigel Stallard

    Version of Record online : 12 JAN 2002, DOI: 10.1046/j.0306-5251.2001.01430.x

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    Interim analyses and sequential designs in phase III studies

    British Journal of Clinical Pharmacology

    Volume 51, Issue 5, May 2001, Pages: 394–399, Susan Todd, Anne Whitehead, Nigel Stallard and John Whitehead

    Version of Record online : 12 JAN 2002, DOI: 10.1046/j.1365-2125.2001.01382.x

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    Group sequential tests for delayed responses (with discussion)

    Journal of the Royal Statistical Society: Series B (Statistical Methodology)

    Volume 75, Issue 1, January 2013, Pages: 3–54, Lisa V. Hampson and Christopher Jennison

    Version of Record online : 4 DEC 2012, DOI: 10.1111/j.1467-9868.2012.01030.x

  9. The management of interim analyses in drug development

    Statistics in Medicine

    Volume 17, Issue 15-16, 15 - 30 August 1998, Pages: 1801–1809, Karen M. Facey and John A. Lewis

    Version of Record online : 21 DEC 1998, DOI: 10.1002/(SICI)1097-0258(19980815/30)17:15/16<1801::AID-SIM981>3.0.CO;2-L

  10. Discussion

    Statistics in Medicine

    Volume 12, Issue 5-6, March 1993, Pages: 493–495,

    Version of Record online : 12 OCT 2006, DOI: 10.1002/sim.4780120514

  11. The management of interim analyses in drug development by Karen M. Facey and John A. Lewis, Statistics in Medicine, 17, 1801–1809 (1998)

    Statistics in Medicine

    Volume 18, Issue 15, 15 August 1999, Pages: 2063–2065, James R. Anderson and David Harrington

    Version of Record online : 3 AUG 1999, DOI: 10.1002/(SICI)1097-0258(19990815)18:15<2063::AID-SIM189>3.0.CO;2-W

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    Primum non nocere: Safety in clinical trials for IPF

    Respirology

    Volume 16, Issue 5, July 2011, Pages: 723–724, Joyce S. Lee and Harold R. Collard

    Version of Record online : 28 JUN 2011, DOI: 10.1111/j.1440-1843.2011.01971.x

  13. Monitoring Trial Progress

    Clinical Trials

    Stuart J. Pocock, Pages: 142–159, 2013

    Published Online : 19 JUL 2013, DOI: 10.1002/9781118793916.ch10

  14. Monitoring of clinical trials and interim analyses from a drug Sponsor's point of view

    Statistics in Medicine

    Volume 12, Issue 5-6, March 1993, Pages: 481–492, George W. Williams, Robert L. Davis, Albert J. Getson, A. Lawrence Gould, Irving K. Hwang, Holly Matthews, Weichung Joseph Shih, Steven M. Snapinn and Karen L. Walton-Bowen

    Version of Record online : 12 OCT 2006, DOI: 10.1002/sim.4780120513

  15. Index to Volume 7

    Journal of the Royal Anthropological Institute

    Volume 7, Issue 4, December 2001, Pages: 831–841,

    Version of Record online : 20 DEC 2002, DOI: 10.1111/1467-9655.00094

  16. Letters to the Editor

    Dermatologic Surgery

    Volume 25, Issue 3, March 1999, Pages: 256–258,

    Version of Record online : 24 DEC 2001, DOI: 10.1046/j.1524-4725.1999.025003256.x

  17. A general statistical principle for changing a design any time during the course of a trial

    Statistics in Medicine

    Volume 23, Issue 16, 30 August 2004, Pages: 2497–2508, Hans-Helge Müller and Helmut Schäfer

    Version of Record online : 27 JUL 2004, DOI: 10.1002/sim.1852

  18. Books Received

    Journal of the Royal Anthropological Institute

    Volume 7, Issue 1, March 2001, Pages: 203–206,

    Version of Record online : 28 JUN 2008, DOI: 10.1111/1467-9655.00058

  19. Exact and asymptotic inference in clinical trials with small event rates under inverse sampling

    Statistics in Medicine

    Volume 34, Issue 19, 30 August 2015, Pages: 2708–2724, Günter Heimann, Mark Von Tress and Mauro Gasparini

    Version of Record online : 15 APR 2015, DOI: 10.1002/sim.6511

  20. Notice

    Nephrology

    Volume 6, Issue 1, February 2001, Page: 45,

    Version of Record online : 7 JUL 2008, DOI: 10.1046/j.1440-1797.2001.00024.x