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There are 5364 results for: content related to: TDP-43, the signature protein of FTLD-U, is a neuronal activity-responsive factor

  1. Review: Transactive response DNA-binding protein 43 (TDP-43): mechanisms of neurodegeneration

    Neuropathology and Applied Neurobiology

    Volume 36, Issue 2, April 2010, Pages: 97–112, T. F. Gendron, K. A. Josephs and L. Petrucelli

    Version of Record online : 23 MAR 2010, DOI: 10.1111/j.1365-2990.2010.01060.x

  2. RNA-binding proteins in neurodegenerative disease: TDP-43 and beyond

    Wiley Interdisciplinary Reviews: RNA

    Volume 3, Issue 2, March/April 2012, Pages: 265–285, Keith A. Hanson, Sang Hwa Kim and Randal S. Tibbetts

    Version of Record online : 25 OCT 2011, DOI: 10.1002/wrna.111

  3. TDP-43 loss of function increases TFEB activity and blocks autophagosome–lysosome fusion

    The EMBO Journal

    Volume 35, Issue 2, 18 January 2016, Pages: 121–142, Qin Xia, Hongfeng Wang, Zongbing Hao, Cheng Fu, Qingsong Hu, Feng Gao, Haigang Ren, Dong Chen, Junhai Han, Zheng Ying and Guanghui Wang

    Version of Record online : 23 DEC 2015, DOI: 10.15252/embj.201591998

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    Redox signalling directly regulates TDP-43 via cysteine oxidation and disulphide cross-linking

    The EMBO Journal

    Volume 31, Issue 5, March 7, 2012, Pages: 1241–1252, Todd J Cohen, Andrew W Hwang, Travis Unger, John Q Trojanowski and Virginia M Y Lee

    Version of Record online : 23 DEC 2011, DOI: 10.1038/emboj.2011.471

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    TDP-43 and FUS/TLS: cellular functions and implications for neurodegeneration

    The FEBS Journal

    Volume 278, Issue 19, October 2011, Pages: 3550–3568, Fabienne C. Fiesel and Philipp J. Kahle

    Version of Record online : 24 AUG 2011, DOI: 10.1111/j.1742-4658.2011.08258.x

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    Knockdown of transactive response DNA-binding protein (TDP-43) downregulates histone deacetylase 6

    The EMBO Journal

    Volume 29, Issue 1, January 6, 2010, Pages: 209–221, Fabienne C Fiesel, Aaron Voigt, Stephanie S Weber, Chris Van den Haute, Andrea Waldenmaier, Karin Görner, Michael Walter, Marlene L Anderson, Jeannine V Kern, Tobias M Rasse, Thorsten Schmidt, Wolfdieter Springer, Roland Kirchner, Michael Bonin, Manuela Neumann, Veerle Baekelandt, Marianna Alunni-Fabbroni, Jörg B Schulz and Philipp J Kahle

    Version of Record online : 12 NOV 2009, DOI: 10.1038/emboj.2009.324

  7. You have full text access to this OnlineOpen article
    Review: Prion-like mechanisms of transactive response DNA binding protein of 43 kDa (TDP-43) in amyotrophic lateral sclerosis (ALS)

    Neuropathology and Applied Neurobiology

    Volume 41, Issue 5, August 2015, Pages: 578–597, Phillip Smethurst, Katie Claire Louise Sidle and John Hardy

    Version of Record online : 20 APR 2015, DOI: 10.1111/nan.12206

  8. Detection of TDP-43 oligomers in frontotemporal lobar degeneration–TDP

    Annals of Neurology

    Volume 78, Issue 2, August 2015, Pages: 211–221, Patricia F. Kao, Yun-Ru Chen, Xiao-Bo Liu, Charles DeCarli, William W. Seeley and Lee-Way Jin

    Version of Record online : 30 JUN 2015, DOI: 10.1002/ana.24431

  9. TAR DNA-binding protein 43 and pathological subtype of Alzheimer's disease impact clinical features

    Annals of Neurology

    Volume 78, Issue 5, November 2015, Pages: 697–709, Keith A. Josephs, Jennifer L. Whitwell, Nirubol Tosakulwong, Stephen D. Weigand, Melissa E. Murray, Amanda M. Liesinger, Leonard Petrucelli, Matthew L. Senjem, Robert J. Ivnik, Joseph E. Parisi, Ronald C. Petersen and Dennis W. Dickson

    Version of Record online : 16 SEP 2015, DOI: 10.1002/ana.24493

  10. You have full text access to this OnlineOpen article
    Spliceosome integrity is defective in the motor neuron diseases ALS and SMA

    EMBO Molecular Medicine

    Volume 5, Issue 2, February 2013, Pages: 221–234, Hitomi Tsuiji, Yohei Iguchi, Asako Furuya, Ayane Kataoka, Hiroyuki Hatsuta, Naoki Atsuta, Fumiaki Tanaka, Yoshio Hashizume, Hiroyasu Akatsu, Shigeo Murayama, Gen Sobue and Koji Yamanaka

    Version of Record online : 25 JAN 2013, DOI: 10.1002/emmm.201202303

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    TDP-43: the relationship between protein aggregation and neurodegeneration in amyotrophic lateral sclerosis and frontotemporal lobar degeneration

    The FEBS Journal

    Volume 278, Issue 19, October 2011, Pages: 3539–3549, Robert H. Baloh

    Version of Record online : 24 AUG 2011, DOI: 10.1111/j.1742-4658.2011.08256.x

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    What is the key player in TDP-43 pathology in ALS: Disappearance from the nucleus or inclusion formation in the cytoplasm?

    Neurology and Clinical Neuroscience

    Volume 1, Issue 1, January 2013, Pages: 11–17, Osamu Onodera, Akihiro Sugai, Takuya Konno, Mari Tada, Akihide Koyama and Masatoyo Nishizawa

    Version of Record online : 31 JAN 2013, DOI: 10.1002/ncn3.9

  13. Rodent Models of Amyotrophic Lateral Sclerosis


    Current Protocols in Pharmacology


    Thomas Philips and Jeffrey D. Rothstein

    Published Online : 1 JUN 2015, DOI: 10.1002/0471141755.ph0567s69

  14. CDC7 inhibition blocks pathological TDP-43 phosphorylation and neurodegeneration

    Annals of Neurology

    Volume 74, Issue 1, July 2013, Pages: 39–52, Nicole F. Liachko, Pamela J. McMillan, Chris R. Guthrie, Thomas D. Bird, James B. Leverenz and Brian C. Kraemer

    Version of Record online : 8 JUL 2013, DOI: 10.1002/ana.23870

  15. Phosphorylated and cleaved TDP-43 in ALS, FTLD and other neurodegenerative disorders and in cellular models of TDP-43 proteinopathy


    Volume 30, Issue 2, April 2010, Pages: 170–181, Tetsuaki Arai, Masato Hasegawa, Takashi Nonoka, Fuyuki Kametani, Makiko Yamashita, Masato Hosokawa, Kazuhiro Niizato, Kuniaki Tsuchiya, Zen Kobayashi, Kenji Ikeda, Mari Yoshida, Mitsumoto Onaya, Hiroshige Fujishiro and Haruhiko Akiyama

    Version of Record online : 19 JAN 2010, DOI: 10.1111/j.1440-1789.2009.01089.x

  16. TDP-35 sequesters TDP-43 into cytoplasmic inclusions through binding with RNA

    FEBS Letters

    Volume 589, Issue 15, July 08, 2015, Pages: 1920–1928, Mei-Xia Che, Lei-Lei Jiang, Hai-Yin Li, Ya-Jun Jiang and Hong-Yu Hu

    Version of Record online : 19 JUN 2015, DOI: 10.1016/j.febslet.2015.06.009

  17. Genetic strategies to study TDP-43 in rodents and to develop preclinical therapeutics for amyotrophic lateral sclerosis

    European Journal of Neuroscience

    Volume 34, Issue 8, October 2011, Pages: 1179–1188, David B. Wang, Michael A. Gitcho, Brian C. Kraemer and Ronald L. Klein

    Version of Record online : 21 JUL 2011, DOI: 10.1111/j.1460-9568.2011.07803.x

  18. Synergistic effect between proteasome and autophagosome in the clearance of polyubiquitinated TDP-43

    Journal of Neuroscience Research

    Volume 88, Issue 4, March 2010, Pages: 784–797, Makoto Urushitani, Takashi Sato, Hitoshi Bamba, Yasuo Hisa and Ikuo Tooyama

    Version of Record online : 1 OCT 2009, DOI: 10.1002/jnr.22243

  19. Abnormal TDP-43 expression is identified in the neocortex in cases of dementia pugilistica, but is mainly confined to the limbic system when identified in high and moderate stages of Alzheimer's disease


    Volume 30, Issue 4, August 2010, Pages: 408–419, Andrew King, Fiona Sweeney, Istvan Bodi, Claire Troakes, Satomi Maekawa and Safa Al-Sarraj

    Version of Record online : 19 JAN 2010, DOI: 10.1111/j.1440-1789.2009.01085.x

  20. You have full text access to this OnlineOpen article
    TDP-1, the Caenorhabditis elegans ortholog of TDP-43, limits the accumulation of double-stranded RNA

    The EMBO Journal

    Volume 33, Issue 24, 17 December 2014, Pages: 2947–2966, Tassa K Saldi, Peter EA Ash, Gavin Wilson, Patrick Gonzales, Alfonso Garrido-Lecca, Christine M Roberts, Vishantie Dostal, Tania F Gendron, Lincoln D Stein, Thomas Blumenthal, Leonard Petrucelli and Christopher D Link

    Version of Record online : 12 NOV 2014, DOI: 10.15252/embj.201488740