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There are 4009 results for: content related to: The up-regulation of BACE1 mediated by hypoxia and ischemic injury: role of oxidative stress and HIF1α

  1. You have free access to this content
    Regulation of β-site APP-cleaving enzyme 1 gene expression and its role in Alzheimer’s Disease

    Journal of Neurochemistry

    Volume 120, Issue s1, January 2012, Pages: 62–70, Xiulian Sun, Kelley Bromley-Brits and Weihong Song

    Article first published online : 28 NOV 2011, DOI: 10.1111/j.1471-4159.2011.07515.x

  2. You have free access to this content
    Intracellular Itinerary of Internalised β-Secretase, BACE1, and Its Potential Impact on β-Amyloid Peptide Biogenesis

    Traffic

    Volume 14, Issue 9, September 2013, Pages: 997–1013, Pei Zhi Cheryl Chia, Wei Hong Toh, Robyn Sharples, Isabelle Gasnereau, Andrew F. Hill and Paul A. Gleeson

    Article first published online : 8 JUL 2013, DOI: 10.1111/tra.12088

  3. You have full text access to this OnlineOpen article
    Neuronal β-amyloid generation is independent of lipid raft association of β-secretase BACE1: analysis with a palmitoylation-deficient mutant

    Brain and Behavior

    Volume 2, Issue 3, May 2012, Pages: 270–282, Kazumi Motoki, Hideaki Kume, Akiko Oda, Akira Tamaoka, Ai Hosaka, Fuyuki Kametani and Wataru Araki

    Article first published online : 29 APR 2012, DOI: 10.1002/brb3.52

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    Function, therapeutic potential and cell biology of BACE proteases: current status and future prospects

    Journal of Neurochemistry

    Volume 130, Issue 1, July 2014, Pages: 4–28, Robert Vassar, Peer-Hendrik Kuhn, Christian Haass, Matthew E. Kennedy, Lawrence Rajendran, Philip C. Wong and Stefan F. Lichtenthaler

    Article first published online : 19 APR 2014, DOI: 10.1111/jnc.12715

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    Identification of a cis-acting element involved in the regulation of BACE1 mRNA alternative splicing

    Journal of Neurochemistry

    Volume 109, Issue 4, May 2009, Pages: 1008–1016, Karen R. Mowrer and Michael S. Wolfe

    Article first published online : 3 MAR 2009, DOI: 10.1111/j.1471-4159.2009.06026.x

  6. You have full text access to this Open Access content
    SCFFbx2-E3-ligase-mediated degradation of BACE1 attenuates Alzheimer’s disease amyloidosis and improves synaptic function

    Aging Cell

    Volume 9, Issue 6, December 2010, Pages: 1018–1031, Bing Gong, Fei Chen, Yong Pan, Isabel Arrieta-Cruz, Yukiko Yoshida, Vahram Haroutunian and Giulio M. Pasinetti

    Article first published online : 29 OCT 2010, DOI: 10.1111/j.1474-9726.2010.00632.x

  7. You have full text access to this OnlineOpen article
    CHIP stabilizes amyloid precursor protein via proteasomal degradation and p53-mediated trans-repression of β-secretase

    Aging Cell

    Volume 14, Issue 4, August 2015, Pages: 595–604, Amir Kumar Singh and Uttam Pati

    Article first published online : 13 MAR 2015, DOI: 10.1111/acel.12335

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    β-Site APP-cleaving enzyme 1 trafficking and Alzheimer’s disease pathogenesis

    Journal of Neurochemistry

    Volume 120, Issue 6, March 2012, Pages: 869–880, Jiangli Tan and Geneviève Evin

    Article first published online : 23 JAN 2012, DOI: 10.1111/j.1471-4159.2011.07623.x

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    Biochemical and kinetic characterization of BACE1: investigation into the putative species-specificity for β- and β′-cleavage sites by human and murine BACE1

    Journal of Neurochemistry

    Volume 91, Issue 6, December 2004, Pages: 1249–1259, Hsiu-Chiung Yang, Xiyun Chai, Marian Mosior, Wayne Kohn, Leonard N. Boggs, Jon A. Erickson, Don B. McClure, Wu-Kuang Yeh, Lianshen Zhang, Patricia Gonzalez-DeWhitt, John P. Mayer, Jose Alfredo Martin, Jingdan Hu, Shu-hui Chen, Ana Belen Bueno, Sheila P. Little, James R. McCarthy and Patrick C. May

    Article first published online : 2 DEC 2004, DOI: 10.1111/j.1471-4159.2004.02764.x

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    Altered β-secretase enzyme kinetics and levels of both BACE1 and BACE2 in the Alzheimer's disease brain

    FEBS Letters

    Volume 580, Issue 28-29, December 11, 2006, Pages: 6550–6560, John H. Stockley, Rivka Ravid and Cora O’Neill

    Article first published online : 13 NOV 2006, DOI: 10.1016/j.febslet.2006.10.076

  11. Significance of transcytosis in Alzheimer's disease: BACE1 takes the scenic route to axons

    BioEssays

    Volume 37, Issue 8, August 2015, Pages: 888–898, Virginie Buggia-Prévot and Gopal Thinakaran

    Article first published online : 30 JUN 2015, DOI: 10.1002/bies.201500019

  12. You have full text access to this OnlineOpen article
    β-Secretase (BACE1) inhibition causes retinal pathology by vascular dysregulation and accumulation of age pigment

    EMBO Molecular Medicine

    Volume 4, Issue 9, September 2012, Pages: 980–991, Jun Cai, Xiaoping Qi, Norbert Kociok, Sergej Skosyrski, Alonso Emilio, Qing Ruan, Song Han, Li Liu, Zhijuan Chen, Catherine Bowes Rickman, Todd Golde, Maria B. Grant, Paul Saftig, Lutgarde Serneels, Bart de Strooper, Antonia M. Joussen and Michael E. Boulton

    Article first published online : 20 AUG 2012, DOI: 10.1002/emmm.201101084

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    Transcriptional and post-transcriptional regulation of β-secretase

    IUBMB Life

    Volume 64, Issue 12, December 2012, Pages: 943–950, Elena Tamagno, M. Guglielmotto, D. Monteleone, A. Vercelli and M. Tabaton

    Article first published online : 26 NOV 2012, DOI: 10.1002/iub.1099

  14. Clec4g (LSECtin) interacts with BACE1 and suppresses Aβ generation

    FEBS Letters

    Volume 589, Issue 13, June 04, 2015, Pages: 1418–1422, Yasuhiko Kizuka, Shinobu Kitazume, Keiko Sato and Naoyuki Taniguchi

    Article first published online : 7 MAY 2015, DOI: 10.1016/j.febslet.2015.04.060

  15. BACE1 Gene Expression and Protein Degradation

    Annals of the New York Academy of Sciences

    Volume 1035, Issue 1, December 2004, Pages: 49–67, WEIHUI ZHOU, HONG QING, YIGANG TONG and WEIHONG SONG

    Article first published online : 12 JAN 2006, DOI: 10.1196/annals.1332.004

  16. You have full text access to this OnlineOpen article
    An aberrant sugar modification of BACE1 blocks its lysosomal targeting in Alzheimer's disease

    EMBO Molecular Medicine

    Volume 7, Issue 2, February 2015, Pages: 175–189, Yasuhiko Kizuka, Shinobu Kitazume, Reiko Fujinawa, Takashi Saito, Nobuhisa Iwata, Takaomi C Saido, Miyako Nakano, Yoshiki Yamaguchi, Yasuhiro Hashimoto, Matthias Staufenbiel, Hiroyuki Hatsuta, Shigeo Murayama, Hiroshi Manya, Tamao Endo and Naoyuki Taniguchi

    Article first published online : 15 JAN 2015, DOI: 10.15252/emmm.201404438

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    Identification and biology of β-secretase

    Journal of Neurochemistry

    Volume 120, Issue s1, January 2012, Pages: 55–61, Patty C. Kandalepas and Robert Vassar

    Article first published online : 28 NOV 2011, DOI: 10.1111/j.1471-4159.2011.07512.x

  18. Camelid heavy chain only antibody fragment domain against β-site of amyloid precursor protein cleaving enzyme 1 inhibits β-secretase activity in vitro and in vivo

    FEBS Journal

    Volume 282, Issue 18, September 2015, Pages: 3618–3631, Bram Dorresteijn, Maarten Rotman, Dorien Faber, Ruud Schravesande, Ernst Suidgeest, Louise van der Weerd, Silvère M. van der Maarel, Cornelis T. Verrips and Mohamed El Khattabi

    Article first published online : 22 JUL 2015, DOI: 10.1111/febs.13367

  19. Reticulons RTN3 and RTN4-B/C interact with BACE1 and inhibit its ability to produce amyloid β-protein

    European Journal of Neuroscience

    Volume 24, Issue 5, September 2006, Pages: 1237–1244, Kiyoko S. Murayama, Fuyuki Kametani, Shinya Saito, Hideaki Kume, Haruhiko Akiyama and Wataru Araki

    Article first published online : 8 SEP 2006, DOI: 10.1111/j.1460-9568.2006.05005.x

  20. Physiological and behavioral effects of amphetamine in BACE1−/− mice

    Genes, Brain and Behavior

    Volume 14, Issue 5, June 2015, Pages: 411–418, R. Madelaine Paredes, E. Piccart, E. Navaira, D. Cruz, M. A. Javors, W. Koek, M. J. Beckstead and C. Walss-Bass

    Article first published online : 21 MAY 2015, DOI: 10.1111/gbb.12222