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There are 26060 results for: content related to: Low-n oligomers as therapeutic targets of Alzheimer’s disease

  1. You have free access to this content
    Soluble Aβ oligomer production and toxicity

    Journal of Neurochemistry

    Volume 120, Issue s1, January 2012, Pages: 125–139, Megan E. Larson and Sylvain E. Lesné

    Article first published online : 28 NOV 2011, DOI: 10.1111/j.1471-4159.2011.07478.x

  2. You have full text access to this Open Access content
    A synthetic amino acid substitution of Tyr10 in Aβ peptide sequence yields a dominant negative variant in amyloidogenesis

    Aging Cell

    Volume 11, Issue 3, June 2012, Pages: 530–541, Honoree Mazargui, Christian Lévêque, Dirk Bartnik, Jacques Fantini, Tiphany Gouget, Mariarosa A. B. Melone, Susanne A. Funke, Dieter Willbold and Lorena Perrone

    Article first published online : 9 APR 2012, DOI: 10.1111/j.1474-9726.2012.00814.x

  3. β-Amyloid Therapeutic Strategies for Alzheimer's Disease

    Standard Article

    Burger's Medicinal Chemistry and Drug Discovery

    Bruno P. Imbimbo and Francesca Speroni

    Published Online : 14 OCT 2005, DOI: 10.1002/0471266949.bmc112

  4. Lipid membrane templates the ordering and induces the fibrillogenesis of Alzheimer's disease amyloid-β peptide

    Proteins: Structure, Function, and Bioinformatics

    Volume 72, Issue 1, July 2008, Pages: 1–24, Eva Y. Chi, Canay Ege, Amy Winans, Jaroslaw Majewski, Guohui Wu, Kristian Kjaer and Ka Yee C. Lee

    Article first published online : 10 JAN 2008, DOI: 10.1002/prot.21887

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    Effects of secreted oligomers of amyloid β-protein on hippocampal synaptic plasticity: a potent role for trimers

    The Journal of Physiology

    Volume 572, Issue 2, April 2006, Pages: 477–492, Matthew Townsend, Ganesh M. Shankar, Tapan Mehta, Dominic M. Walsh and Dennis J. Selkoe

    Article first published online : 5 APR 2006, DOI: 10.1113/jphysiol.2005.103754

  6. A Strategy for Designing a Peptide Probe for Detection of β-Amyloid Oligomers

    ChemBioChem

    Volume 11, Issue 17, November 22, 2010, Pages: 2409–2418, Yang Hu, Baihao Su, Dr. Chung-Sei Kim, Michael Hernandez, Prof. Agueda Rostagno, Prof. Jorge Ghiso and Prof. Jin Ryoun Kim

    Article first published online : 28 OCT 2010, DOI: 10.1002/cbic.201000435

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    Aβ Oligomers – a decade of discovery

    Journal of Neurochemistry

    Volume 101, Issue 5, June 2007, Pages: 1172–1184, Dominic M. Walsh and Dennis J. Selkoe

    Article first published online : 4 JAN 2007, DOI: 10.1111/j.1471-4159.2006.04426.x

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    Low-density lipoprotein receptor-related protein-1: a serial clearance homeostatic mechanism controlling Alzheimer’s amyloid β-peptide elimination from the brain

    Journal of Neurochemistry

    Volume 115, Issue 5, December 2010, Pages: 1077–1089, Berislav V. Zlokovic, Rashid Deane, Abhay P. Sagare, Robert D. Bell and Ethan A. Winkler

    Article first published online : 5 OCT 2010, DOI: 10.1111/j.1471-4159.2010.07002.x

  9. You have full text access to this Open Access content
    Amyloid-β-induced occludin down-regulation and increased permeability in human brain endothelial cells is mediated by MAPK activation

    Journal of Cellular and Molecular Medicine

    Volume 14, Issue 5, May 2010, Pages: 1101–1112, L. M. Tai, K. A. Holloway, D. K. Male, A. J. Loughlin and I. A. Romero

    Article first published online : 2 APR 2009, DOI: 10.1111/j.1582-4934.2009.00717.x

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    Amyloid-beta oligomers increase the localization of prion protein at the cell surface

    Journal of Neurochemistry

    Volume 117, Issue 3, May 2011, Pages: 538–553, Fabiana A. Caetano, Flavio H. Beraldo, Glaucia N. M. Hajj, Andre L. Guimaraes, Sofia Jürgensen, Ana Paula Wasilewska-Sampaio, Pedro H. F. Hirata, Ivana Souza, Cleiton F. Machado, Daisy Y.-L. Wong, Fernanda G. De Felice, Sergio T. Ferreira, Vania F. Prado, R. Jane Rylett, Vilma R. Martins and Marco A. M. Prado

    Article first published online : 23 MAR 2011, DOI: 10.1111/j.1471-4159.2011.07225.x

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    Highly conserved and disease-specific patterns of carboxyterminally truncated Aβ peptides 1–37/38/39 in addition to 1–40/42 in Alzheimer's disease and in patients with chronic neuroinflammation

    Journal of Neurochemistry

    Volume 81, Issue 3, May 2002, Pages: 481–496, J. Wiltfang, H. Esselmann, M. Bibl, A. Smirnov, M. Otto, S. Paul, B. Schmidt, H.-W. Klafki, M. Maler, T. Dyrks, M. Bienert, M. Beyermann, E. Rüther and J. Kornhuber

    Article first published online : 29 APR 2002, DOI: 10.1046/j.1471-4159.2002.00818.x

  12. Oligomeric Aβ in Alzheimer's Disease: Relationship to Plaque and Tangle Pathology, APOE Genotype and Cerebral Amyloid Angiopathy

    Brain Pathology

    Volume 20, Issue 2, March 2010, Pages: 468–480, Zoë Van Helmond, James S. Miners, Patrick G. Kehoe and Seth Love

    Article first published online : 16 JUL 2009, DOI: 10.1111/j.1750-3639.2009.00321.x

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    Sensitive ELISA detection of amyloid-β protofibrils in biological samples

    Journal of Neurochemistry

    Volume 103, Issue 1, October 2007, Pages: 334–345, Hillevi Englund, Dag Sehlin, Ann-Sofi Johansson, Lars N. G. Nilsson, Pär Gellerfors, Staffan Paulie, Lars Lannfelt and Frida Ekholm Pettersson

    Article first published online : 9 JUN 2007, DOI: 10.1111/j.1471-4159.2007.04759.x

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    A monoclonal antibody against synthetic Aβ dimer assemblies neutralizes brain-derived synaptic plasticity-disrupting Aβ

    Journal of Neurochemistry

    Volume 119, Issue 1, October 2011, Pages: 189–201, Brian O’Nuallain, Igor Klyubin, Jessica M. Mc Donald, James S. Foster, Alfred Welzel, Andrew Barry, Richard K. Dykoski, James P. Cleary, Martijn F.B.G. Gebbink, Michael J. Rowan and Dominic M. Walsh

    Article first published online : 22 AUG 2011, DOI: 10.1111/j.1471-4159.2011.07389.x

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    Selective induction of calcineurin activity and signaling by oligomeric amyloid beta

    Aging Cell

    Volume 7, Issue 6, December 2008, Pages: 824–835, Lindsay C. Reese, WenRu Zhang, Kelly T. Dineley, Rakez Kayed and Giulio Taglialatela

    Article first published online : 8 SEP 2008, DOI: 10.1111/j.1474-9726.2008.00434.x

  16. The immune system, amyloid-β peptide, and Alzheimer's disease

    Immunological Reviews

    Volume 205, Issue 1, June 2005, Pages: 244–256, Marc E. Weksler, Gunnar Gouras, Norman R. Relkin and Paul Szabo

    Article first published online : 9 MAY 2005, DOI: 10.1111/j.0105-2896.2005.00264.x

  17. The use of mass spectrometry to study amyloid-β peptides

    Mass Spectrometry Reviews

    Volume 30, Issue 3, May/June 2011, Pages: 347–365, Giuseppe Grasso

    Article first published online : 22 NOV 2010, DOI: 10.1002/mas.20281

  18. You have full text access to this Open Access content
    Amyloid-β(1-42) alters structure and function of retinal pigmented epithelial cells

    Aging Cell

    Volume 8, Issue 2, April 2009, Pages: 162–177, Julien Bruban, Anne-Lise Glotin, Virginie Dinet, Naïma Chalour, Florian Sennlaub, Laurent Jonet, Na An, Anne Marie Faussat and Frédéric Mascarelli

    Article first published online : 23 FEB 2009, DOI: 10.1111/j.1474-9726.2009.00456.x

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    Antibody-based approaches in Alzheimer’s research: safety, pharmacokinetics, metabolism, and analytical tools

    Journal of Neurochemistry

    Volume 104, Issue 4, February 2008, Pages: 859–874, Peter Lichtlen and M. Hasan Mohajeri

    Article first published online : 18 AUG 2008, DOI: 10.1111/j.1471-4159.2007.05064.x

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    A case for a non-transgenic animal model of Alzheimer's disease

    Genes, Brain and Behavior

    Volume 4, Issue 3, April 2005, Pages: 157–172, A. Stéphan and A. G. Phillips

    Article first published online : 28 JAN 2005, DOI: 10.1111/j.1601-183X.2004.00113.x