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There are 8661 results for: content related to: Regulated intramembrane proteolysis – lessons from amyloid precursor protein processing

  1. Functional reconstitution of γ-secretase through coordinated expression of presenilin, nicastrin, Aph-1, and Pen-2

    Journal of Neuroscience Research

    Volume 77, Issue 3, 1 August 2004, Pages: 309–322, Goran Periz and Mark E. Fortini

    Version of Record online : 14 JUN 2004, DOI: 10.1002/jnr.20203

  2. Distinct presenilin-dependent and presenilin-independent γ-secretases are responsible for total cellular Aβ production

    Journal of Neuroscience Research

    Volume 74, Issue 3, 1 November 2003, Pages: 361–369, Christina A. Wilson, Robert W. Doms and Virginia M.-Y. Lee

    Version of Record online : 28 OCT 2003, DOI: 10.1002/jnr.10776

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    Take five—BACE and the γ-secretase quartet conduct Alzheimer's amyloid β-peptide generation

    The EMBO Journal

    Volume 23, Issue 3, February 11, 2004, Pages: 483–488, Christian Haass

    Version of Record online : 29 JAN 2004, DOI: 10.1038/sj.emboj.7600061

  4. Identity and function of γ-secretase

    Journal of Neuroscience Research

    Volume 74, Issue 3, 1 November 2003, Pages: 353–360, W. Taylor Kimberly and Michael S. Wolfe

    Version of Record online : 28 OCT 2003, DOI: 10.1002/jnr.10736

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    Important functional role of residue x of the presenilin GxGD protease active site motif for APP substrate cleavage specificity and substrate selectivity of γ-secretase

    Journal of Neurochemistry

    Volume 125, Issue 1, April 2013, Pages: 144–156, Benedikt Kretner, Akio Fukumori, Peer-Hendrik Kuhn, Blanca Isabel Pérez-Revuelta, Stefan F. Lichtenthaler, Christian Haass and Harald Steiner

    Version of Record online : 15 JAN 2013, DOI: 10.1111/jnc.12124

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    Membrane Trafficking Pathways in Alzheimer's Disease

    Traffic

    Volume 13, Issue 6, June 2012, Pages: 759–770, Lawrence Rajendran and Wim Annaert

    Version of Record online : 17 FEB 2012, DOI: 10.1111/j.1600-0854.2012.01332.x

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    Active γ-secretase is localized to detergent-resistant membranes in human brain

    The FEBS Journal

    Volume 275, Issue 6, March 2008, Pages: 1174–1187, Ji-Yeun Hur, Hedvig Welander, Homira Behbahani, Mikio Aoki, Jenny Frånberg, Bengt Winblad, Susanne Frykman and Lars O. Tjernberg

    Version of Record online : 6 FEB 2008, DOI: 10.1111/j.1742-4658.2008.06278.x

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    APPε, the ε-secretase-derived N-terminal product of the β-amyloid precursor protein, behaves as a type I protein and undergoes α-, β-, and γ-secretase cleavages

    Journal of Neurochemistry

    Volume 97, Issue 3, May 2006, Pages: 807–817, Solveig Lefranc-Jullien, Claire Sunyach and Frédéric Checler

    Version of Record online : 8 MAR 2006, DOI: 10.1111/j.1471-4159.2006.03748.x

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    The physiology of the β-amyloid precursor protein intracellular domain AICD

    Journal of Neurochemistry

    Volume 120, Issue s1, January 2012, Pages: 109–124, Raphaëlle Pardossi-Piquard and Frédéric Checler

    Version of Record online : 28 NOV 2011, DOI: 10.1111/j.1471-4159.2011.07475.x

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    β-Site APP-cleaving enzyme 1 trafficking and Alzheimer’s disease pathogenesis

    Journal of Neurochemistry

    Volume 120, Issue 6, March 2012, Pages: 869–880, Jiangli Tan and Geneviève Evin

    Version of Record online : 23 JAN 2012, DOI: 10.1111/j.1471-4159.2011.07623.x

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    Hypoxia/ischemia activate processing of Amyloid Precursor Protein: impact of vascular dysfunction in the pathogenesis of Alzheimer's disease

    Journal of Neurochemistry

    Volume 140, Issue 4, February 2017, Pages: 536–549, Antero Salminen, Anu Kauppinen and Kai Kaarniranta

    Version of Record online : 9 JAN 2017, DOI: 10.1111/jnc.13932

  12. IFN-γ-induced BACE1 expression is mediated by activation of JAK2 and ERK1/2 signaling pathways and direct binding of STAT1 to BACE1 promoter in astrocytes

    Glia

    Volume 55, Issue 3, February 2007, Pages: 253–262, Hyun Jin Cho, Su-Kyoung Kim, Seok Min Jin, Eun-Mi Hwang, Yong Sik Kim, Kyoon Huh and Inhee Mook-Jung

    Version of Record online : 7 NOV 2006, DOI: 10.1002/glia.20451

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    Novel modulators of amyloid-β precursor protein processing

    Journal of Neurochemistry

    Volume 100, Issue 2, January 2007, Pages: 314–323, Bor Luen Tang and Yih Cherng Liou

    Version of Record online : 2 OCT 2006, DOI: 10.1111/j.1471-4159.2006.04215.x

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    Substrate recruitment of γ-secretase and mechanism of clinical presenilin mutations revealed by photoaffinity mapping

    The EMBO Journal

    Volume 35, Issue 15, 01 August 2016, Pages: 1628–1643, Akio Fukumori and Harald Steiner

    Version of Record online : 24 MAY 2016, DOI: 10.15252/embj.201694151

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    Presenilin endoproteolysis mediated by an aspartyl protease activity pharmacologically distinct from γ-secretase

    Journal of Neurochemistry

    Volume 85, Issue 6, June 2003, Pages: 1563–1574, William A. Campbell, Megan L. O. Reed, Jennifer Strahle, Michael S. Wolfe and Weiming Xia

    Version of Record online : 13 MAY 2003, DOI: 10.1046/j.1471-4159.2003.01799.x

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    Ubiquitin–proteasome pathway mediates degradation of APH-1

    Journal of Neurochemistry

    Volume 99, Issue 5, December 2006, Pages: 1403–1412, Guiqiong He, Hong Qing, Fang Cai, Clement Kwok, Huaxi Xu, Gang Yu, Alan Bernstein and Weihong Song

    Version of Record online : 21 AUG 2006, DOI: 10.1111/j.1471-4159.2006.04184.x

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    Selecting cells with different Alzheimer's disease γ-secretase activity using FACS

    European Journal of Biochemistry

    Volume 270, Issue 3, February 2003, Pages: 495–506, M. Fleur Sernee, Geneviève Evin, Janetta G. Culvenor, José A. Villadangos, Konrad Beyreuther, Colin L. Masters and Roberto Cappai

    Version of Record online : 13 JAN 2003, DOI: 10.1046/j.1432-1033.2003.03405.x

  18. Approaches to Amyloid Therapies for the Treatment of Alzheimer's Disease

    Standard Article

    Burger's Medicinal Chemistry and Drug Discovery

    Albert J. Robichaud, Ji-In Kim and J. Steven Jacobsen

    Published Online : 15 SEP 2010, DOI: 10.1002/0471266949.bmc249

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    Presenilins mediate a dual intramembranous γ-secretase cleavage of Notch-1

    The EMBO Journal

    Volume 21, Issue 20, October 15, 2002, Pages: 5408–5416, Masayasu Okochi, Harald Steiner, Akio Fukumori, Hisashi Tanii, Taisuke Tomita, Toshihisa Tanaka, Takeshi Iwatsubo, Takashi Kudo, Masatoshi Takeda and Christian Haass

    Version of Record online : 15 OCT 2002, DOI: 10.1093/emboj/cdf541

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    Function, therapeutic potential and cell biology of BACE proteases: current status and future prospects

    Journal of Neurochemistry

    Volume 130, Issue 1, July 2014, Pages: 4–28, Robert Vassar, Peer-Hendrik Kuhn, Christian Haass, Matthew E. Kennedy, Lawrence Rajendran, Philip C. Wong and Stefan F. Lichtenthaler

    Version of Record online : 19 APR 2014, DOI: 10.1111/jnc.12715