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There are 11295 results for: content related to: Oxidative stress and aberrant signaling in aging and cognitive decline

  1. The Current State of NAD+-Dependent Histone Deacetylases (Sirtuins) as Novel Therapeutic Targets

    Medicinal Research Reviews

    Volume 38, Issue 1, January 2018, Pages: 147–200, Matthias Schiedel, Dina Robaa, Tobias Rumpf, Wolfgang Sippl and Manfred Jung

    Version of Record online : 17 JAN 2017, DOI: 10.1002/med.21436

  2. Anti-aging properties of melatonin in an in vitro murine senescence model: involvement of the sirtuin 1 pathway

    Journal of Pineal Research

    Volume 47, Issue 3, October 2009, Pages: 228–237, M. Tajes, J. Gutierrez-Cuesta, D. Ortuño-Sahagun, A. Camins and Mercè Pallàs

    Version of Record online : 23 JUL 2009, DOI: 10.1111/j.1600-079X.2009.00706.x

  3. Neurons from senescence-accelerated SAMP8 mice are protected against frailty by the sirtuin 1 promoting agents melatonin and resveratrol

    Journal of Pineal Research

    Volume 52, Issue 3, April 2012, Pages: 271–281, Rosa Cristòfol, David Porquet, Rubén Corpas, Ana Coto-Montes, Jofre Serret, Antoni Camins, Mercè Pallàs and Coral Sanfeliu

    Version of Record online : 16 NOV 2011, DOI: 10.1111/j.1600-079X.2011.00939.x

  4. The sirtuins: Markers of metabolic health

    Molecular Nutrition & Food Research

    Volume 60, Issue 1, January 2016, Pages: 79–91, Jeffrey D. Covington and Sudip Bajpeyi

    Version of Record online : 7 DEC 2015, DOI: 10.1002/mnfr.201500340

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    Fenofibrate inhibits atrial metabolic remodelling in atrial fibrillation through PPAR-α/sirtuin 1/PGC-1α pathway

    British Journal of Pharmacology

    Volume 173, Issue 6, March 2016, Pages: 1095–1109, Guang-zhong Liu, Ting-ting Hou, Yue Yuan, Peng-zhou Hang, Jing-jing Zhao, Li Sun, Guan-qi Zhao, Jing Zhao, Jing-mei Dong, Xiao-bing Wang, Hang Shi, Yong-wu Liu, Jing-hua Zhou, Zeng-xiang Dong, Yang Liu, Cheng-chuang Zhan, Yue Li and Wei-min Li

    Version of Record online : 18 FEB 2016, DOI: 10.1111/bph.13438

  6. You have full text access to this OnlineOpen article
    Alternate deacylating specificities of the archaeal sirtuins Sir2Af1 and Sir2Af2

    Protein Science

    Volume 23, Issue 12, December 2014, Pages: 1686–1697, Alison E. Ringel, Christina Roman and Cynthia Wolberger

    Version of Record online : 1 OCT 2014, DOI: 10.1002/pro.2546

  7. Development of Substrate-Derived Sirtuin Inhibitors with Potential Anticancer Activity

    ChemMedChem

    Volume 12, Issue 20, October 20, 2017, Pages: 1703–1714, Dr. Nora Kuhlmann, Dr. Constance Chollet, Linda Baldus, Prof. Dr. Ines Neundorf and Dr. Michael Lammers

    Version of Record online : 25 SEP 2017, DOI: 10.1002/cmdc.201700414

  8. Sirtuin activators and inhibitors

    BioFactors

    Volume 38, Issue 5, September/October 2012, Pages: 349–359, José M. Villalba and Francisco J. Alcaín

    Version of Record online : 25 JUN 2012, DOI: 10.1002/biof.1032

  9. You have full text access to this OnlineOpen article
    Sirtuins at the crossroads of stemness, aging, and cancer

    Aging Cell

    Volume 16, Issue 6, December 2017, Pages: 1208–1218, Carol O'Callaghan and Athanassios Vassilopoulos

    Version of Record online : 10 OCT 2017, DOI: 10.1111/acel.12685

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    Activation of TRPV1 attenuates high salt-induced cardiac hypertrophy through improvement of mitochondrial function

    British Journal of Pharmacology

    Volume 172, Issue 23, December 2015, Pages: 5548–5558, Hongmei Lang, Qiang Li, Hao Yu, Peng Li, Zongshi Lu, Shiqiang Xiong, Tao Yang, Yu Zhao, Xiaohu Huang, Peng Gao, Hexuan Zhang, Qianhui Shang, Daoyan Liu and Zhiming Zhu

    Version of Record online : 12 JAN 2015, DOI: 10.1111/bph.12987

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    Specific functions for the fission yeast Sirtuins Hst2 and Hst4 in gene regulation and retrotransposon silencing

    The EMBO Journal

    Volume 26, Issue 10, May 16, 2007, Pages: 2477–2488, Mickaël Durand-Dubief, Indranil Sinha, Fredrik Fagerström-Billai, Carolina Bonilla, Anthony Wright, Michael Grunstein and Karl Ekwall

    Version of Record online : 19 APR 2007, DOI: 10.1038/sj.emboj.7601690

  12. Sirtuins are Unaffected by PARP Inhibitors Containing Planar Nicotinamide Bioisosteres

    Chemical Biology & Drug Design

    Volume 87, Issue 3, March 2016, Pages: 478–482, Torun Ekblad and Herwig Schüler

    Version of Record online : 26 NOV 2015, DOI: 10.1111/cbdd.12680

  13. You have full text access to this Open Access content
    Sirtuin-independent effects of nicotinamide on lifespan extension from calorie restriction in yeast

    Aging Cell

    Volume 5, Issue 6, December 2006, Pages: 505–514, Mitsuhiro Tsuchiya, Nick Dang, Emily O. Kerr, Di Hu, Kristan K. Steffen, Jonathan A. Oakes, Brian K. Kennedy and Matt Kaeberlein

    Version of Record online : 2 OCT 2006, DOI: 10.1111/j.1474-9726.2006.00240.x

  14. Structure–Activity Studies on Suramin Analogues as Inhibitors of NAD+-Dependent Histone Deacetylases (Sirtuins)

    ChemMedChem

    Volume 2, Issue 10, October 8, 2007, Pages: 1419–1431, Johannes Trapp, Rene Meier, Darunee Hongwiset, Matthias U. Kassack, Wolfgang Sippl and Manfred Jung

    Version of Record online : 12 JUL 2007, DOI: 10.1002/cmdc.200700003

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    Structure of Sir2Tm bound to a propionylated peptide

    Protein Science

    Volume 20, Issue 1, January 2011, Pages: 131–139, Poonam Bheda, Jennifer T. Wang, Jorge C. Escalante-Semerena and Cynthia Wolberger

    Version of Record online : 23 DEC 2010, DOI: 10.1002/pro.544

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    Sirtuin-dependent epigenetic regulation in the maintenance of genome integrity

    The FEBS Journal

    Volume 282, Issue 9, May 2015, Pages: 1745–1767, Laia Bosch-Presegué and Alejandro Vaquero

    Version of Record online : 13 OCT 2014, DOI: 10.1111/febs.13053

  17. You have full text access to this OnlineOpen article
    Highlights of the Keystone Symposium: sirtuins in metabolism, aging and disease

    EMBO Molecular Medicine

    Volume 4, Issue 7, July 2012, Pages: 557–560, Michele M. Maxwell, Julien Francisco Zaldivar-Jolissaint, Antonello Mai, Tiago F. Outeiro and Aleksey G. Kazanstev

    Version of Record online : 18 MAY 2012, DOI: 10.1002/emmm.201201452

    Corrected by:

    Corrigendum: Corrigendum

    Vol. 4, Issue 8, 840, Version of Record online: 3 AUG 2012

  18. Contrasting sirtuin and poly(ADP-ribose)polymerase activities of selected 2,4,6-trisubstituted benzimidazoles

    Chemical Biology & Drug Design

    Keng Yoon Yeong, Soo Choon Tan, Chun-Wai Mai, Chee-Onn Leong, Felicia Fei-Lei Chung, Yean Kee Lee, Chin Fei Chee and Noorsaadah Abdul Rahman

    Version of Record online : 9 AUG 2017, DOI: 10.1111/cbdd.13072

  19. Thiobarbiturates as Sirtuin Inhibitors: Virtual Screening, Free-Energy Calculations, and Biological Testing

    ChemMedChem

    Volume 3, Issue 12, December 15, 2008, Pages: 1965–1976, Urszula Uciechowska, Jörg Schemies, Robert C. Neugebauer, Elisabeth-Maria Huda, Martin L. Schmitt, Rene Meier, Eric Verdin, Manfred Jung and Wolfgang Sippl

    Version of Record online : 4 NOV 2008, DOI: 10.1002/cmdc.200800104

  20. Zinc neurotoxicity is dependent on intracellular NAD+ levels and the sirtuin pathway

    European Journal of Neuroscience

    Volume 24, Issue 8, October 2006, Pages: 2169–2176, Ai-Li Cai, Gregory J. Zipfel and Christian T. Sheline

    Version of Record online : 16 OCT 2006, DOI: 10.1111/j.1460-9568.2006.05110.x