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There are 10830 results for: content related to: Association of common genetic variation in the insulin/IGF1 signaling pathway with human longevity

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    Replication of an association of variation in the FOXO3A gene with human longevity using both case–control and longitudinal data

    Aging Cell

    Volume 9, Issue 6, December 2010, Pages: 1010–1017, Mette Soerensen, Serena Dato, Kaare Christensen, Matt McGue, Tinna Stevnsner, Vilhelm A. Bohr and Lene Christiansen

    Article first published online : 21 OCT 2010, DOI: 10.1111/j.1474-9726.2010.00627.x

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    SIRT2 deacetylates FOXO3a in response to oxidative stress and caloric restriction

    Aging Cell

    Volume 6, Issue 4, August 2007, Pages: 505–514, Fei Wang, Margaret Nguyen, F. Xiao-Feng Qin and Qiang Tong

    Article first published online : 18 APR 2007, DOI: 10.1111/j.1474-9726.2007.00304.x

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    Regulation of replicative senescence by insulin-like growth factor-binding protein 3 in human umbilical vein endothelial cells

    Aging Cell

    Volume 6, Issue 4, August 2007, Pages: 535–545, Kwang Seok Kim, Min-Sun Kim, Young Bae Seu, Hae Young Chung, Jung Hye Kim and Jae-Ryong Kim

    Article first published online : 6 JUN 2007, DOI: 10.1111/j.1474-9726.2007.00315.x

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    Insulin-activated Akt rescues Aβ oxidative stress-induced cell death by orchestrating molecular trafficking

    Aging Cell

    Volume 10, Issue 5, October 2011, Pages: 832–843, Pasquale Picone, Daniela Giacomazza, Valeria Vetri, Rita Carrotta, Valeria Militello, Pier L. San Biagio and Marta Di Carlo

    Article first published online : 8 JUL 2011, DOI: 10.1111/j.1474-9726.2011.00724.x

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    Methionine sulfoxide reductase A expression is regulated by the DAF-16/FOXO pathway in Caenorhabditis elegans

    Aging Cell

    Volume 8, Issue 6, December 2009, Pages: 690–705, Alicia N. Minniti, Romina Cataldo, Carla Trigo, Luis Vasquez, Patricio Mujica, Federico Leighton, Nibaldo C. Inestrosa and Rebeca Aldunate

    Article first published online : 11 SEP 2009, DOI: 10.1111/j.1474-9726.2009.00521.x

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    Human longevity and common variations in the LMNA gene: a meta-analysis

    Aging Cell

    Volume 11, Issue 3, June 2012, Pages: 475–481, Karen N. Conneely, Brian C. Capell, Michael R. Erdos, Paola Sebastiani, Nadia Solovieff, Amy J. Swift, Clinton T. Baldwin, Temuri Budagov, Nir Barzilai, Gil Atzmon, Annibale A. Puca, Thomas T. Perls, Bard J. Geesaman, Michael Boehnke and Francis S. Collins

    Article first published online : 27 MAR 2012, DOI: 10.1111/j.1474-9726.2012.00808.x

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    Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited

    Aging Cell

    Volume 10, Issue 4, August 2011, Pages: 686–698, Joris Deelen, Marian Beekman, Hae-Won Uh, Quinta Helmer, Maris Kuningas, Lene Christiansen, Dennis Kremer, Ruud van der Breggen, H. Eka D. Suchiman, Nico Lakenberg, Erik B. van den Akker, Willemijn M. Passtoors, Henning Tiemeier, Diana van Heemst, Anton J. de Craen, Fernando Rivadeneira, Eco J de Geus, Markus Perola, Frans J. van der Ouderaa, David A. Gunn, Dorret I. Boomsma, André G. Uitterlinden, Kaare Christensen, Cornelia M. van Duijn, Bastiaan T. Heijmans, Jeanine J. Houwing-Duistermaat, Rudi G. J. Westendorp and P. Eline Slagboom

    Article first published online : 5 MAY 2011, DOI: 10.1111/j.1474-9726.2011.00705.x

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    Post-transcriptional regulation of IGF1R by key microRNAs in long–lived mutant mice

    Aging Cell

    Volume 10, Issue 6, December 2011, Pages: 1080–1088, Ruqiang Liang, Amit Khanna, Senthilkumar Muthusamy, Na Li, Harshini Sarojini, John J. Kopchick, Michal M. Masternak, Andrzej Bartke and Eugenia Wang

    Article first published online : 14 NOV 2011, DOI: 10.1111/j.1474-9726.2011.00751.x

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    Genome-wide linkage analysis for human longevity: Genetics of Healthy Aging Study

    Aging Cell

    Volume 12, Issue 2, April 2013, Pages: 184–193, Marian Beekman, Hélène Blanché, Markus Perola, Anti Hervonen, Vladyslav Bezrukov, Ewa Sikora, Friederike Flachsbart, Lene Christiansen, Anton J. M. De Craen, Tom B. L. Kirkwood, Irene Maeve Rea, Michel Poulain, Jean-Marie Robine, Silvana Valensin, Maria Antonietta Stazi, Giuseppe Passarino, Luca Deiana, Efstathios S. Gonos, Lavinia Paternoster, Thorkild I. A. Sørensen, Qihua Tan, Quinta Helmer, Erik B. van den Akker, Joris Deelen, Francesca Martella, Heather J. Cordell, Kristin L. Ayers, James W. Vaupel, Outi Törnwall, Thomas E. Johnson, Stefan Schreiber, Mark Lathrop, Axel Skytthe, Rudi G. J. Westendorp, Kaare Christensen, Jutta Gampe, Almut Nebel, Jeanine J. Houwing-Duistermaat, Pieternella Eline Slagboom, Claudio Franceschi and the GEHA consortium

    Article first published online : 6 FEB 2013, DOI: 10.1111/acel.12039

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    HRAS1 and LASS1 with APOE are associated with human longevity and healthy aging

    Aging Cell

    Volume 9, Issue 5, October 2010, Pages: 698–708, S. Michal Jazwinski, Sangkyu Kim, Jianliang Dai, Li Li, Xiuhua Bi, James C. Jiang, Jonathan Arnold, Mark A. Batzer, Jerilyn A. Walker, David A. Welsh, Christina M. Lefante, Julia Volaufova, Leann Myers, L. Joseph Su, Dorothy B. Hausman, Michael V. Miceli, Eric Ravussin, Leonard W. Poon, Katie E. Cherry, Michael A. Welsch and for the Georgia Centenarian Study and the Louisiana Healthy Aging Study

    Article first published online : 21 JUN 2010, DOI: 10.1111/j.1474-9726.2010.00600.x

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    Hormone replacement therapy enhances IGF-1 signaling in skeletal muscle by diminishing miR-182 and miR-233 expressions: a study on postmenopausal monozygotic twin pairs

    Aging Cell

    Fabiola Olivieri, Maarit Ahtiainen, Raffaella Lazzarini, Eija Pöllänen, Miriam Capri, Maria Lorenzi, Gianluca Fulgenzi, Maria C. Albertini, Stefano Salvioli, Markku J. Alen, Urho M. Kujala, Giulia Borghetti, Lucia Babini, Jaakko Kaprio, Sarianna Sipilä, Claudio Franceschi, Vuokko Kovanen and Antonio D. Procopio

    Article first published online : 18 JUL 2014, DOI: 10.1111/acel.12245

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    Mitochondrially encoded methionine is inversely related to longevity in mammals

    Aging Cell

    Volume 10, Issue 2, April 2011, Pages: 198–207, Juan Carlos Aledo, Yang Li, João Pedro de Magalhães, Manuel Ruíz-Camacho and Juan Antonio Pérez-Claros

    Article first published online : 29 DEC 2010, DOI: 10.1111/j.1474-9726.2010.00657.x

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    The extreme longevity of Arctica islandica is associated with increased peroxidation resistance in mitochondrial membranes

    Aging Cell

    Volume 11, Issue 5, October 2012, Pages: 845–855, Daniel Munro and Pierre U. Blier

    Article first published online : 25 JUL 2012, DOI: 10.1111/j.1474-9726.2012.00847.x

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    Mitochondrial gene expression and increased oxidative metabolism: role in increased lifespan of fat-specific insulin receptor knock-out mice

    Aging Cell

    Volume 6, Issue 6, December 2007, Pages: 827–839, Masa Katic, Adam R. Kennedy, Igor Leykin, Andrew Norris, Aileen McGettrick, Stephane Gesta, Steven J. Russell, Matthias Bluher, Eleftheria Maratos-Flier and C. Ronald Kahn

    Article first published online : 24 SEP 2007, DOI: 10.1111/j.1474-9726.2007.00346.x

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    Candidate gene study of FOXO1, FOXO4, and FOXO6 reveals no association with human longevity in Germans

    Aging Cell

    Volume 10, Issue 4, August 2011, Pages: 622–628, Rabea Kleindorp, Friederike Flachsbart, Annibale A. Puca, Alberto Malovini, Stefan Schreiber and Almut Nebel

    Article first published online : 12 APR 2011, DOI: 10.1111/j.1474-9726.2011.00698.x

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    Aging in inbred strains of mice: study design and interim report on median lifespans and circulating IGF1 levels

    Aging Cell

    Volume 8, Issue 3, June 2009, Pages: 277–287, Rong Yuan, Shirng-Wern Tsaih, Stefka B. Petkova, Caralina Marin De Evsikova, Shuqin Xing, Michael A. Marion, Molly A. Bogue, Kevin D. Mills, Luanne L. Peters, Carol J. Bult, Clifford J. Rosen, John P. Sundberg, David E. Harrison, Gary A. Churchill and Beverly Paigen

    Article first published online : 9 APR 2009, DOI: 10.1111/j.1474-9726.2009.00478.x

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    The PI3K-Akt pathway inhibits senescence and promotes self-renewal of human skin-derived precursors in vitro

    Aging Cell

    Volume 10, Issue 4, August 2011, Pages: 661–674, Shuang Liu, Shu Liu, Xinyue Wang, Jiaxi Zhou, Yujing Cao, Fei Wang and Enkui Duan

    Article first published online : 3 MAY 2011, DOI: 10.1111/j.1474-9726.2011.00704.x

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    FoxO1 is involved in the antineoplastic effect of calorie restriction

    Aging Cell

    Volume 9, Issue 3, June 2010, Pages: 372–382, Haruyoshi Yamaza, Toshimitsu Komatsu, Saori Wakita, Carole Kijogi, Seongjoon Park, Hiroko Hayashi, Takuya Chiba, Ryoichi Mori, Tatsuo Furuyama, Nozomu Mori and Isao Shimokawa

    Article first published online : 6 MAR 2010, DOI: 10.1111/j.1474-9726.2010.00563.x

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    Testing the ‘free radical theory of aging’ hypothesis: physiological differences in long-lived and short-lived colubrid snakes

    Aging Cell

    Volume 6, Issue 3, June 2007, Pages: 395–404, Kylie A. Robert, Anja Brunet-Rossinni and Anne M. Bronikowski

    Article first published online : 16 FEB 2007, DOI: 10.1111/j.1474-9726.2007.00287.x

  20. You have full text access to this Open Access content
    Age-related behaviors have distinct transcriptional profiles in Caenorhabditis elegans

    Aging Cell

    Volume 7, Issue 6, December 2008, Pages: 850–865, Tamara R. Golden, Alan Hubbard, Caroline Dando, Michael A. Herren and Simon Melov

    Article first published online : 5 SEP 2008, DOI: 10.1111/j.1474-9726.2008.00433.x