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There are 9121 results for: content related to: Resistance to experimental tumorigenesis in cells of a long-lived mammal, the naked mole-rat ( Heterocephalus glaber )

  1. You have full text access to this Open Access content
    A mutant telomerase defective in nuclear-cytoplasmic shuttling fails to immortalize cells and is associated with mitochondrial dysfunction

    Aging Cell

    Volume 9, Issue 2, April 2010, Pages: 203–219, Olga A. Kovalenko, Matthieu J. Caron, Perihan Ulema, Carolina Medrano, Andrew P. Thomas, Masayuki Kimura, Marcelo G. Bonini, Utz Herbig and Janine H. Santos

    Article first published online : 18 JAN 2010, DOI: 10.1111/j.1474-9726.2010.00551.x

  2. You have full text access to this Open Access content
    Understanding and exploiting hTERT promoter regulation for diagnosis and treatment of human cancers

    Cancer Science

    Volume 99, Issue 8, August 2008, Pages: 1528–1538, Satoru Kyo, Masahiro Takakura, Toshiyoshi Fujiwara and Masaki Inoue

    Article first published online : 14 AUG 2008, DOI: 10.1111/j.1349-7006.2008.00878.x

  3. You have full text access to this Open Access content
    Mitochondrial hTERT exacerbates free-radical-mediated mtDNA damage

    Aging Cell

    Volume 3, Issue 6, December 2004, Pages: 399–411, Janine Hertzog Santos, Joel N. Meyer, Milan Skorvaga, Lois A. Annab and Bennett Van Houten

    Article first published online : 24 SEP 2004, DOI: 10.1111/j.1474-9728.2004.00124.x

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    hTERT mutations associated with idiopathic pulmonary fibrosis affect telomerase activity, telomere length, and cell growth by distinct mechanisms

    Aging Cell

    Volume 11, Issue 3, June 2012, Pages: 482–490, Allison R. Tsang, Haley D.M. Wyatt, Nicholas S.Y. Ting and Tara L. Beattie

    Article first published online : 19 MAR 2012, DOI: 10.1111/j.1474-9726.2012.00810.x

  5. You have free access to this content
    Cytotoxic T cell responses to human telomerase reverse transcriptase in patients with hepatocellular carcinoma

    Hepatology

    Volume 43, Issue 6, June 2006, Pages: 1284–1294, Eishiro Mizukoshi, Yasunari Nakamoto, Yohei Marukawa, Kuniaki Arai, Tatsuya Yamashita, Hirokazu Tsuji, Kiyotaka Kuzushima, Masafumi Takiguchi and Shuichi Kaneko

    Article first published online : 25 MAY 2006, DOI: 10.1002/hep.21203

  6. Epithelial–mesenchymal transition and mesenchymal–epithelial transition are essential for the acquisition of stem cell properties in hTERT-immortalised oral epithelial cells

    Biology of the Cell

    Volume 104, Issue 8, August 2012, Pages: 476–489, Bin Qiao, Vinod Gopalan, Zhifeng Chen, Robert Anthony Smith, Qian Tao and Alfred King-yin Lam

    Article first published online : 4 JUN 2012, DOI: 10.1111/boc.201100077

  7. Serine/threonine-protein phosphatase 2A physically interacts with human telomerase reverse transcriptase hTERT and regulates its subcellular distribution

    Journal of Cellular Biochemistry

    Volume 114, Issue 2, February 2013, Pages: 409–417, Peng Xi, Lili Zhou, Miao Wang, Jun-Ping Liu and Yu-Sheng Cong

    Article first published online : 17 DEC 2012, DOI: 10.1002/jcb.24378

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    Recombinant adenovirus-mediated human telomerase reverse transcriptase gene can stimulate cell proliferation and maintain primitive characteristics in bovine mammary gland epithelial cells

    Development, Growth & Differentiation

    Volume 53, Issue 3, April 2011, Pages: 312–322, Xiao-Ying He, Yue-Mao Zheng, Jie Lan, Yue-Hong Wu, Jing Yan, Xiao-Ning He, Tuo Zhang, Yu-Long He, Yan-Ling Zheng and Yong Zhang

    Article first published online : 30 MAR 2011, DOI: 10.1111/j.1440-169X.2010.01236.x

  9. hTERT- and hCTLA4Ig-expressing human bone marrow-derived mesenchymal stem cells: in vitro and in vivo characterization and osteogenic differentiation

    Journal of Tissue Engineering and Regenerative Medicine

    Fei Dai, Sisi Yang, Fei Zhang, Dongwen Shi, Zehua Zhang, Jun Wu and Jianzhong Xu

    Article first published online : 22 JUL 2014, DOI: 10.1002/term.1924

  10. Potent antitumor effect of TRAIL mediated by a novel adeno-associated viral vector targeting to telomerase activity for human hepatocellular carcinoma

    The Journal of Gene Medicine

    Volume 10, Issue 5, May 2008, Pages: 518–526, Yigang Wang, Fang Huang, Haibo Cai, Suyang Zhong, Xinyuan Liu and Wen-Song Tan

    Article first published online : 14 MAR 2008, DOI: 10.1002/jgm.1177

  11. You have full text access to this Open Access content
    Establishment of functional telomerase immortalized human hepatocytes and a hepatic stellate cell line for telomere-targeting anticancer drug development

    Cancer Science

    Volume 101, Issue 7, July 2010, Pages: 1678–1685, Koji Waki, Kumiko Anno, Taeko Ono, Toshinori Ide, Kazuaki Chayama and Hidetoshi Tahara

    Article first published online : 23 MAR 2010, DOI: 10.1111/j.1349-7006.2010.01576.x

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    Microarray analyses in bladder cancer cells: Inhibition of hTERT expression down-regulates EGFR

    International Journal of Cancer

    Volume 119, Issue 6, 15 September 2006, Pages: 1276–1284, Kai Kraemer, Uta Schmidt, Susanne Fuessel, Alexander Herr, Manfred P. Wirth and Axel Meye

    Article first published online : 13 APR 2006, DOI: 10.1002/ijc.21975

  13. Rearrangement of upstream sequences of the hTERT gene during cellular immortalization

    Genes, Chromosomes and Cancer

    Volume 48, Issue 11, November 2009, Pages: 963–974, Yuanjun Zhao, Shuwen Wang, Evgenya Y. Popova, Sergei A. Grigoryev and Jiyue Zhu

    Article first published online : 11 AUG 2009, DOI: 10.1002/gcc.20698

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    HPV16-E6 associated hTERT promoter acetylation is E6AP dependent, increased in later passage cells and enhanced by loss of p300

    International Journal of Cancer

    Volume 119, Issue 8, 15 October 2006, Pages: 1878–1885, Michael A. James, John H. Lee and Aloysius J. Klingelhutz

    Article first published online : 17 MAY 2006, DOI: 10.1002/ijc.22064

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    Involvement of 14-3-3 proteins in nuclear localization of telomerase

    The EMBO Journal

    Volume 19, Issue 11, June 1, 2000, Pages: 2652–2661, Hiroyuki Seimiya, Hiroko Sawada, Yukiko Muramatsu, Mayuko Shimizu, Kumiko Ohko, Kazuhiko Yamane and Takashi Tsuruo

    Article first published online : 1 JUN 2000, DOI: 10.1093/emboj/19.11.2652

  16. You have free access to this content
    hTERT inhibits the Epstein-Barr virus lytic cycle and promotes the proliferation of primary B lymphocytes: Implications for EBV-driven lymphomagenesis

    International Journal of Cancer

    Volume 121, Issue 3, 1 August 2007, Pages: 576–587, Liliana Terrin, Riccardo Dolcetti, Irene Corradini, Stefano Indraccolo, Jessica Dal Col, Roberta Bertorelle, Laura Bonaldi, Giovanni Esposito and Anita De Rossi

    Article first published online : 6 APR 2007, DOI: 10.1002/ijc.22661

  17. Amplification of the telomerase reverse transcriptase (hTERT) gene in cervical carcinomas

    Genes, Chromosomes and Cancer

    Volume 34, Issue 3, July 2002, Pages: 269–275, Anju Zhang, Chengyun Zheng, Mi Hou, Charlotta Lindvall, Keng-Ling Wallin, Tord Ångström, Xiaoyan Yang, Ann-Cathrin Hellström, Elisabeth Blennow, Magnus Björkholm, Anders Zetterberg, Astrid Gruber and Dawei Xu

    Article first published online : 26 FEB 2002, DOI: 10.1002/gcc.10071

  18. Bovine microvascular endothelial cells immortalized with human telomerase

    Journal of Cellular Biochemistry

    Volume 98, Issue 2, 15 May 2006, Pages: 267–286, Raphaële Buser, Roberto Montesano, Irène Garcia, Philippe Dupraz and Michael S. Pepper

    Article first published online : 11 JAN 2006, DOI: 10.1002/jcb.20715

  19. Implication of human telomerase reverse transcriptase in cervical carcinogenesis and cancer recurrence

    International Journal of Gynecological Cancer

    Volume 16, Issue 5, September/October 2006, Pages: 1873–1879, P.-H. WANG and J.-L. KO

    Article first published online : 17 JUL 2006, DOI: 10.1111/j.1525-1438.2006.00659.x

  20. Proteomic analysis of human bone marrow mesenchymal stem cells transduced with human telomerase reverse transcriptase gene during proliferation

    Cell Proliferation

    Volume 41, Issue 4, August 2008, Pages: 625–644, G. P. Huang, Z. J. Pan, J. P. Huang, J. F. Yang, C. J. Guo, Y. G. Wang, Q. Zheng, R. Chen, Y. L. Xu, G. Z. Wang, Y. M. Xi, D. Shen, J. Jin and J. F. Wang

    Article first published online : 8 JUL 2008, DOI: 10.1111/j.1365-2184.2008.00543.x