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There are 20844 results for: content related to: At the crossroads of longevity and metabolism: the metabolic syndrome and lifespan determinant pathways

  1. You have free access to this content
    The interplay between p66Shc, reactive oxygen species and cancer cell metabolism

    European Journal of Clinical Investigation

    Volume 45, Issue s1, January 2015, Pages: 25–31, Magdalena Lebiedzinska-Arciszewska, Monika Oparka, Ignacio Vega-Naredo, Agnieszka Karkucinska-Wieckowska, Paolo Pinton, Jerzy Duszynski and Mariusz R. Wieckowski

    Version of Record online : 18 DEC 2014, DOI: 10.1111/eci.12364

  2. New aspects of p66Shc in ischaemia reperfusion injury and other cardiovascular diseases

    British Journal of Pharmacology

    Fabio Di Lisa, Marco Giorgio, Peter Ferdinandy and Rainer Schulz

    Version of Record online : 14 APR 2016, DOI: 10.1111/bph.13478

  3. Carnosic acid alleviates chronic alcoholic liver injury by regulating the SIRT1/ChREBP and SIRT1/p66shc pathways in rats

    Molecular Nutrition & Food Research

    Volume 60, Issue 9, September 2016, Pages: 1902–1911, Lili Gao, Wen Shan, Wenjing Zeng, Yan Hu, Guangzhi Wang, Xiaofeng Tian, Ning Zhang, Xue Shi, Yan Zhao, Chunchun Ding, Feng Zhang, Kexin Liu and Jihong Yao

    Version of Record online : 12 JUL 2016, DOI: 10.1002/mnfr.201500878

  4. p66Shc longevity protein regulates the proliferation of human ovarian cancer cells

    Molecular Carcinogenesis

    Volume 54, Issue 8, August 2015, Pages: 618–631, Sakthivel Muniyan, Yu-Wei Chou, Te-Jung Tsai, Paul Thomes, Suresh Veeramani, Benedict B. Benigno, L. DeEtte Walker, John F. McDonald, Shafiq A. Khan, Fen-Fen Lin, Subodh M. Lele and Ming-Fong Lin

    Version of Record online : 7 JAN 2014, DOI: 10.1002/mc.22129

  5. Elevated p66Shc is associated with intracellular redox imbalance in developmentally compromised bovine embryos

    Molecular Reproduction and Development

    Volume 80, Issue 1, January 2013, Pages: 22–34, Nathan T. Bain, Pavneesh Madan and Dean H. Betts

    Version of Record online : 26 NOV 2012, DOI: 10.1002/mrd.22128

  6. You have full text access to this Open Access content
    The p66Shc knockout mice are short lived under natural condition

    Aging Cell

    Volume 11, Issue 1, February 2012, Pages: 162–168, Marco Giorgio, Alessandra Berry, Ina Berniakovich, Inga Poletaeva, Mirella Trinei, Massimo Stendardo, Kevork Hagopian, Jon J. Ramsey, Gino Cortopassi, Enrica Migliaccio, Sarah Nötzli, Irmgard Amrein, Hans P. Lipp, Francesca Cirulli and Pier G. Pelicci

    Version of Record online : 28 DEC 2011, DOI: 10.1111/j.1474-9726.2011.00770.x

  7. D,L-sulforaphane-induced apoptosis in human breast cancer cells is regulated by the adapter protein p66Shc

    Journal of Cellular Biochemistry

    Volume 113, Issue 2, February 2012, Pages: 599–610, Kozue Sakao and Shivendra V. Singh

    Version of Record online : 5 JAN 2012, DOI: 10.1002/jcb.23386

  8. You have full text access to this OnlineOpen article
    P66SHC deletion improves fertility and progeric phenotype of late-generation TERC-deficient mice but not their short lifespan

    Aging Cell

    Volume 15, Issue 3, June 2016, Pages: 446–454, Marco Giorgio, Massimo Stendardo, Enrica Migliaccio and Pier Giuseppe Pelicci

    Version of Record online : 10 MAR 2016, DOI: 10.1111/acel.12448

  9. Positive and negative regulation of antigen receptor signaling by the Shc family of protein adapters

    Immunological Reviews

    Volume 232, Issue 1, November 2009, Pages: 115–134, Francesca Finetti, Maria Teresa Savino and Cosima T. Baldari

    Version of Record online : 23 OCT 2009, DOI: 10.1111/j.1600-065X.2009.00826.x

  10. p66Shc is involved in promoting HIF-1α accumulation and cell death in hypoxic T cells

    Journal of Cellular Physiology

    Volume 211, Issue 2, May 2007, Pages: 439–447, Fabio Carraro, Annalisa Pucci, Michela Pellegrini, Pier Giuseppe Pelicci, Cosima T. Baldari and Antonella Naldini

    Version of Record online : 13 DEC 2006, DOI: 10.1002/jcp.20951

  11. You have free access to this content
    Alteration of p66shc is associated with endothelial dysfunction in the abdominal aortic coarctation of rats

    FEBS Letters

    Volume 582, Issue 17, July 23, 2008, Pages: 2561–2566, Sang Ki Lee, Hyo Shin Kim, Yun Jeong Song, Hee Kyoung Joo, Ji Young Lee, Kwon Ho Lee, Eun Jung Cho, Chung-Hyun Cho, Jin Bong Park and Byeong Hwa Jeon

    Version of Record online : 25 JUN 2008, DOI: 10.1016/j.febslet.2008.06.026

  12. Measuring p66Shc Signaling Pathway Activation and Mitochondrial Translocation in Cultured Cells


    Current Protocols in Toxicology


    Mariusz R. Wieckowski, Cláudia M. Deus, Renata Couto, Monika Oparka, Magdalena Lebiedzińska-Arciszewska, Jerzy Duszyński and Paulo J. Oliveira

    Published Online : 2 NOV 2015, DOI: 10.1002/0471140856.tx2506s66

  13. Reduction of p66Shc suppresses oxidative damage in retinal pigmented epithelial cells and retina

    Journal of Cellular Physiology

    Volume 209, Issue 3, December 2006, Pages: 996–1005, Zhihao Wu, Brian Rogers, Shu Kachi, Sean F. Hackett, Anna Sick and Peter A. Campochiaro

    Version of Record online : 13 SEP 2006, DOI: 10.1002/jcp.20819

  14. 17β-Estradiol Abrogates Apoptosis Inhibiting PKCδ, JNK, and p66Shc Activation in C2C12 Cells

    Journal of Cellular Biochemistry

    Volume 116, Issue 7, July 2015, Pages: 1454–1465, Anabela La Colla, Ricardo Boland and Andrea Vasconsuelo

    Version of Record online : 12 MAY 2015, DOI: 10.1002/jcb.25107

  15. You have free access to this content
    Negative regulation of immunoreceptor signaling by protein adapters: Shc proteins join the club

    FEBS Letters

    Volume 584, Issue 24, December 15, 2010, Pages: 4915–4922, Nagaja Capitani, Orso M. Lucherini and Cosima T. Baldari

    Version of Record online : 7 SEP 2010, DOI: 10.1016/j.febslet.2010.08.046

  16. You have full text access to this Open Access content
    The Shc locus regulates insulin signaling and adiposity in mammals

    Aging Cell

    Volume 10, Issue 1, February 2011, Pages: 55–65, Alexey A. Tomilov, Jon J. Ramsey, Kevork Hagopian, Marco Giorgio, Kyoungmi M. Kim, Adam Lam, Enrica Migliaccio, Kent C. Lloyd, Ina Berniakovich, Tomas A. Prolla, PierGiuseppe Pelicci and Gino A. Cortopassi

    Version of Record online : 15 NOV 2010, DOI: 10.1111/j.1474-9726.2010.00641.x

  17. You have free access to this content
    p66Shc/Notch-3 Interplay Controls Self-Renewal and Hypoxia Survival in Human Stem/Progenitor Cells of the Mammary Gland Expanded In Vitro as Mammospheres


    Volume 25, Issue 3, March 2007, Pages: 807–815, Pasquale Sansone, Gianluca Storci, Catia Giovannini, Silvia Pandolfi, Simona Pianetti, Mario Taffurelli, Donatella Santini, Claudio Ceccarelli, Pasquale Chieco and Massimiliano Bonafé

    Version of Record online : 7 DEC 2006, DOI: 10.1634/stemcells.2006-0442

  18. DNA methylation of the p66Shc promoter is decreased in placental tissue from women delivering intrauterine growth restricted neonates

    Prenatal Diagnosis

    Volume 33, Issue 5, May 2013, Pages: 484–491, Anja Tzschoppe, Helmuth Doerr, Wolfgang Rascher, Tamme Goecke, Matthias Beckmann, Ralf Schild, Ellen Struwe, Jürgen Geisel, Heike Jung and Jörg Dötsch

    Version of Record online : 26 MAR 2013, DOI: 10.1002/pd.4096

  19. Activation of AQP4, p66Shc and endoplasmic reticulum stress is involved in inflammation by carrageenan and is suppressed by argirein, a derivative of rhein

    Journal of Pharmacy and Pharmacology

    Volume 64, Issue 8, August 2012, Pages: 1138–1145, Xiao-Dong Cong, You Wu, De-Zai Dai, Ming-Jian Ding, Yun Zhang and Yin Dai

    Version of Record online : 27 MAR 2012, DOI: 10.1111/j.2042-7158.2012.01507.x

  20. You have full text access to this OnlineOpen article
    let-7-repressesed Shc translation delays replicative senescence

    Aging Cell

    Volume 13, Issue 1, February 2014, Pages: 185–192, Fang Xu, Lijun Pang, Xiaoyu Cai, Xinwen Liu, Shuai Yuan, Xiuqin Fan, Bin Jiang, Xiaowei Zhang, Yali Dou, Myriam Gorospe and Wengong Wang

    Version of Record online : 25 NOV 2013, DOI: 10.1111/acel.12176