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There are 42582 results for: content related to: Exercise acts as a drug; the pharmacological benefits of exercise

  1. You have free access to this content
    AMP-activated protein kinase is required for exercise-induced peroxisome proliferator-activated receptor γ co-activator 1α translocation to subsarcolemmal mitochondria in skeletal muscle

    The Journal of Physiology

    Volume 591, Issue 6, March 2013, Pages: 1551–1561, Brennan K. Smith, Kazutaka Mukai, James S. Lally, Amy C. Maher, Brendon J. Gurd, George J. F. Heigenhauser, Lawrence L. Spriet and Graham P. Holloway

    Version of Record online : 22 FEB 2013, DOI: 10.1113/jphysiol.2012.245944

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    Reactive oxygen and nitrogen species as intracellular signals in skeletal muscle

    The Journal of Physiology

    Volume 589, Issue 9, May 2011, Pages: 2129–2138, Scott K. Powers, Erin E. Talbert and Peter J. Adhihetty

    Version of Record online : 27 APR 2011, DOI: 10.1113/jphysiol.2010.201327

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    Lack of adequate appreciation of physical exercise's complexities can pre-empt appropriate design and interpretation in scientific discovery

    The Journal of Physiology

    Volume 587, Issue 23, December 2009, Pages: 5527–5539, F. W. Booth and M. J. Laye

    Version of Record online : 30 NOV 2009, DOI: 10.1113/jphysiol.2009.179507

  4. Exercise: the lifelong supplement for healthy ageing and slowing down the onset of frailty

    The Journal of Physiology

    Volume 594, Issue 8, 15 April 2016, Pages: 1989–1999, Jose Viña, Leocadio Rodriguez-Mañas, Andrea Salvador-Pascual, Francisco José Tarazona-Santabalbina and Mari Carmen Gomez-Cabrera

    Version of Record online : 14 APR 2016, DOI: 10.1113/JP270536

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    PGC1-α over-expression prevents metabolic alterations and soleus muscle atrophy in hindlimb unloaded mice

    The Journal of Physiology

    Volume 592, Issue 20, 15 October 2014, Pages: 4575–4589, Jessica Cannavino, Lorenza Brocca, Marco Sandri, Roberto Bottinelli and Maria Antonietta Pellegrino

    Version of Record online : 9 SEP 2014, DOI: 10.1113/jphysiol.2014.275545

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    Exercise training attenuates the hypermuscular phenotype and restores skeletal muscle function in the myostatin null mouse

    Experimental Physiology

    Volume 97, Issue 1, January 2012, Pages: 125–140, Antonios Matsakas, Raymond Macharia, Anthony Otto, Mohamed I. Elashry, Etienne Mouisel, Vanina Romanello, Roberta Sartori, Helge Amthor, Marco Sandri, Vihang Narkar and Ketan Patel

    Version of Record online : 8 DEC 2011, DOI: 10.1113/expphysiol.2011.063008

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    Nitric oxide and AMPK cooperatively regulate PGC-1α in skeletal muscle cells

    The Journal of Physiology

    Volume 588, Issue 18, September 2010, Pages: 3551–3566, Vitor A. Lira, Dana L. Brown, Ana K. Lira, Andreas N. Kavazis, Quinlyn A. Soltow, Elizabeth H. Zeanah and David S. Criswell

    Version of Record online : 16 SEP 2010, DOI: 10.1113/jphysiol.2010.194035

  8. You have full text access to this OnlineOpen article
    Coupling of mitochondrial function and skeletal muscle fiber type by a miR-499/Fnip1/AMPK circuit

    EMBO Molecular Medicine

    Volume 8, Issue 10, October 2016, Pages: 1212–1228, Jing Liu, Xijun Liang, Danxia Zhou, Ling Lai, Liwei Xiao, Lin Liu, Tingting Fu, Yan Kong, Qian Zhou, Rick B Vega, Min-Sheng Zhu, Daniel P Kelly, Xiang Gao and Zhenji Gan

    Version of Record online : 9 AUG 2016, DOI: 10.15252/emmm.201606372

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    Training-induced mitochondrial adaptation: role of peroxisome proliferator-activated receptor γ coactivator-1α, nuclear factor-κB and β-blockade

    Experimental Physiology

    Volume 98, Issue 3, March 2013, Pages: 784–795, Hong Feng, Chounghun Kang, Jonathan R. Dickman, Ryan Koenig, Iwalola Awoyinka, Yong Zhang and Li Li Ji

    Version of Record online : 17 DEC 2012, DOI: 10.1113/expphysiol.2012.069286

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    Effect of exercise on mouse liver and brain bioenergetic infrastructures

    Experimental Physiology

    Volume 98, Issue 1, January 2013, Pages: 207–219, Lezi E., Jianghua Lu, Jeffrey M. Burns and Russell H. Swerdlow

    Version of Record online : 17 OCT 2012, DOI: 10.1113/expphysiol.2012.066688

  11. You have full text access to this OnlineOpen article
    Macrophage PPAR gamma Co-activator-1 alpha participates in repressing foam cell formation and atherosclerosis in response to conjugated linoleic acid

    EMBO Molecular Medicine

    Volume 5, Issue 9, September 2013, Pages: 1443–1457, Cathal McCarthy, Nora T. Lieggi, Denis Barry, Declan Mooney, Monica de Gaetano, William G. James, Sarah McClelland, Mary C. Barry, Laure Escoubet-Lozach, Andrew C. Li, Christopher K Glass, Desmond J. Fitzgerald and Orina Belton

    Version of Record online : 21 AUG 2013, DOI: 10.1002/emmm.201302587

  12. Sestrins: Novel antioxidant and AMPK-modulating functions regulated by exercise?

    Journal of Cellular Physiology

    Volume 228, Issue 8, August 2013, Pages: 1647–1650, Fabian Sanchis-Gomar

    Version of Record online : 18 APR 2013, DOI: 10.1002/jcp.24338

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    Peroxisome Proliferator–Activated Receptor γ Coactivator 1α and FoxO3A Mediate Chondroprotection by AMP-Activated Protein Kinase

    Arthritis & Rheumatology

    Volume 66, Issue 11, November 2014, Pages: 3073–3082, Xianling Zhao, Freyr Petursson, Benoit Viollet, Martin Lotz, Robert Terkeltaub and Ru Liu-Bryan

    Version of Record online : 26 OCT 2014, DOI: 10.1002/art.38791

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    Vitamin C and E supplementation hampers cellular adaptation to endurance training in humans: a double-blind, randomised, controlled trial

    The Journal of Physiology

    Volume 592, Issue 8, April 2014, Pages: 1887–1901, Gøran Paulsen, Kristoffer T. Cumming, Geir Holden, Jostein Hallén, Bent Ronny Rønnestad, Ole Sveen, Arne Skaug, Ingvild Paur, Nasser E. Bastani, Hege Nymo Østgaard, Charlotte Buer, Magnus Midttun, Fredrik Freuchen, Håvard Wiig, Elisabeth Tallaksen Ulseth, Ina Garthe, Rune Blomhoff, Haakon B. Benestad and Truls Raastad

    Version of Record online : 12 MAR 2014, DOI: 10.1113/jphysiol.2013.267419

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    Peroxisome proliferator-activated receptor gamma coactivator-1 alpha (PGC-1α) upregulated E-cadherin expression in HepG2 cells

    FEBS Letters

    Volume 582, Issue 5, March 05, 2008, Pages: 627–634, Hui-Ju Lee, Yeu Su, Wing-Yiu Lui, Gar-Yang Chau, Pen-Hui Yin, Hsin-Chen Lee and Chin-Wen Chi

    Version of Record online : 31 JAN 2008, DOI: 10.1016/j.febslet.2008.01.033

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    Repeated transient mRNA bursts precede increases in transcriptional and mitochondrial proteins during training in human skeletal muscle

    The Journal of Physiology

    Volume 588, Issue 23, December 2010, Pages: 4795–4810, Christopher G. R. Perry, James Lally, Graham P. Holloway, George J. F. Heigenhauser, Arend Bonen and Lawrence L. Spriet

    Version of Record online : 30 NOV 2010, DOI: 10.1113/jphysiol.2010.199448

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    Mitofusins 1/2 and ERRα expression are increased in human skeletal muscle after physical exercise

    The Journal of Physiology

    Volume 567, Issue 1, August 2005, Pages: 349–358, Romain Cartoni, Bertrand Léger, M. Benjamin Hock, Manu Praz, Antoinette Crettenand, Sara Pich, Jean-Luc Ziltener, François Luthi, Olivier Dériaz, Antonio Zorzano, Charles Gobelet, Anastasia Kralli and Aaron P. Russell

    Version of Record online : 10 AUG 2005, DOI: 10.1113/jphysiol.2005.092031

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    PGC-1α gene transfer improves muscle function in dystrophic muscle following prolonged disease progress

    Experimental Physiology

    Volume 100, Issue 10, 1 October 2015, Pages: 1145–1158, Katrin Hollinger and Joshua T. Selsby

    Version of Record online : 8 SEP 2015, DOI: 10.1113/EP085339

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    Free fatty acids increase PGC-1α expression in isolated rat islets

    FEBS Letters

    Volume 579, Issue 6, February 28, 2005, Pages: 1446–1452, Peixiang Zhang, Chang Liu, Chunni Zhang, Yan Zhang, Pingping Shen, Junfeng Zhang and Chen-Yu Zhang

    Version of Record online : 1 FEB 2005, DOI: 10.1016/j.febslet.2005.01.046

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    Metabolic adaptations through the PGC-1α and SIRT1 pathways

    FEBS Letters

    Volume 582, Issue 1, January 09, 2008, Pages: 46–53, Joseph T. Rodgers, Carles Lerin, Zachary Gerhart-Hines and Pere Puigserver

    Version of Record online : 26 NOV 2007, DOI: 10.1016/j.febslet.2007.11.034