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There are 1008 results for: content related to: Antihypertensive Efficacy of the Oral Direct Renin Inhibitor Aliskiren as Add-On Therapy in Patients Not Responding to Amlodipine Monotherapy

  1. Pharmacokinetics of the Oral Direct Renin Inhibitor Aliskiren in Combination With Digoxin, Atorvastatin, and Ketoconazole in Healthy Subjects: The Role of P-Glycoprotein in the Disposition of Aliskiren

    The Journal of Clinical Pharmacology

    Volume 48, Issue 11, November 2008, Pages: 1323–1338, Dr Sujata Vaidyanathan, Dr Gian Camenisch, Dr Helmut Schuetz, Ms Christine Reynolds, Dr Ching-Ming Yeh, Dr Marie-Noelle Bizot, Dr Hans Armin Dieterich, Dr Dan Howard and Dr William P. Dole

    Version of Record online : 7 MAR 2013, DOI: 10.1177/0091270008323258

  2. You have free access to this content
    Aliskiren in the Treatment of Hypertension and Organ Damage

    Cardiovascular Therapeutics

    Volume 29, Issue 1, February 2011, Pages: 77–87, Graziano Riccioni

    Version of Record online : 25 NOV 2010, DOI: 10.1111/j.1755-5922.2010.00230.x

  3. Lack of pharmacokinetic interactions of aliskiren, a novel direct renin inhibitor for the treatment of hypertension, with the antihypertensives amlodipine, valsartan, hydrochlorothiazide (HCTZ) and ramipril in healthy volunteers

    International Journal of Clinical Practice

    Volume 60, Issue 11, November 2006, Pages: 1343–1356, S. VAIDYANATHAN, J. VALENCIA, C. KEMP, C. ZHAO, C-M. YEH, M-N. BIZOT, J. DENOUEL, H. A. DIETERICH and W. P. DOLE

    Version of Record online : 11 OCT 2006, DOI: 10.1111/j.1742-1241.2006.01164.x

  4. Effects of the inhibition of intestinal P-glycoprotein on aliskiren pharmacokinetics in cynomolgus monkeys

    Biopharmaceutics & Drug Disposition

    Volume 36, Issue 1, January 2015, Pages: 15–33, Mikiko Tsukimoto, Rikiya Ohashi, Nao Torimoto, Yoko Togo, Takashi Suzuki, Toshio Maeda and Yoshiyuki Kagawa

    Version of Record online : 31 OCT 2014, DOI: 10.1002/bdd.1920

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    Pharmacokinetic Interaction of the Direct Renin Inhibitor Aliskiren with Furosemide and Extended-Release Isosorbide-5-Mononitrate in Healthy Subjects

    Cardiovascular Therapeutics

    Volume 26, Issue 4, Winter 2008, Pages: 238–246, Sujata Vaidyanathan, Michael Bartlett, Hans Armin Dieterich, Ching-Ming Yeh, Ana Antunes, Dan Howard and William P. Dole

    Version of Record online : 11 NOV 2008, DOI: 10.1111/j.1755-5922.2008.00058.x

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    Safety and Tolerability of the Direct Renin Inhibitor Aliskiren in Combination With Angiotensin Receptor Blockers and Thiazide Diuretics: A Pooled Analysis of Clinical Experience of 12,942 Patients

    The Journal of Clinical Hypertension

    Volume 13, Issue 7, July 2011, Pages: 506–516, William B. White, Robert Bresalier, Allen P. Kaplan, Biff F. Palmer, Robert H. Riddell, Anastasia Lesogor, William Chang and Deborah L. Keefe

    Version of Record online : 18 MAR 2011, DOI: 10.1111/j.1751-7176.2011.00438.x

  7. Blood pressure lowering efficacy of renin inhibitors for primary hypertension

    Intervention Review

    The Cochrane Library

    Vijaya M Musini, Patricia M Fortin, Ken Bassett and James M Wright

    Published Online : 8 OCT 2008, DOI: 10.1002/14651858.CD007066.pub2

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    Aliskiren as a novel therapeutic agent for hypertension and cardio-renal diseases

    Journal of Pharmacy and Pharmacology

    Volume 64, Issue 4, April 2012, Pages: 470–481, Azhar Rashikh, Shibli Jameel Ahmad, Krishna Kolappa Pillai and Abul Kalam Najmi

    Version of Record online : 7 DEC 2011, DOI: 10.1111/j.2042-7158.2011.01414.x

  9. Effects of Aliskiren, a Direct Renin Inhibitor, on Cardiac Repolarization and Conduction in Healthy Subjects

    The Journal of Clinical Pharmacology

    Volume 48, Issue 7, July 2008, Pages: 799–811, Dr Surya Ayalasomayajula, Dr Ching-Ming Yeh, Dr Sujata Vaidyanathan, Mr Brian Flannery, Dr Hans Armin Dieterich, Dr Dan Howard, Dr Martin P. Bedigian and Dr William P. Dole

    Version of Record online : 7 MAR 2013, DOI: 10.1177/0091270008319330

  10. Aliskiren reduces portal pressure in portal hypertensive rats

    European Journal of Clinical Investigation

    Volume 42, Issue 5, May 2012, Pages: 526–533, Ching-Chih Chang, Wen-Shin Lee, Hui-Chun Huang, Fa-Yauh Lee, Sun-Sang Wang, Han-Chieh Lin, Jing-Yi Nong and Shou-Dong Lee

    Version of Record online : 24 OCT 2011, DOI: 10.1111/j.1365-2362.2011.02611.x

  11. Efficacy, Safety, and Tolerability of Aliskiren Monotherapy Administered With a Light Meal in Elderly Hypertensive Patients: A Randomized, Double-Blind, Placebo-Controlled, Dose-Response Evaluation Study

    The Journal of Clinical Pharmacology

    Volume 52, Issue 12, December 2012, Pages: 1901–1911, Dr Giuseppe Villa, Ms Stephanie Le Breton, Mr Ghionul Ibram and Mr Deborah L. Keefe

    Version of Record online : 7 MAR 2013, DOI: 10.1177/0091270011426432

  12. Effect of Verapamil on the Pharmacokinetics of Aliskiren in Healthy Participants

    The Journal of Clinical Pharmacology

    Volume 51, Issue 2, February 2011, Pages: 218–228, Sam Rebello, Selene Leon, Sam Hariry, Marion Dahlke and Venkateswar Jarugula

    Version of Record online : 7 MAR 2013, DOI: 10.1177/0091270010365717

  13. Effect of Cyclosporine on the Pharmacokinetics of Aliskiren in Healthy Subjects

    The Journal of Clinical Pharmacology

    Volume 51, Issue 11, November 2011, Pages: 1549–1560, Dr Sam Rebello, Dr Séverine Compain, Dr Aimin Feng, Mr Sam Hariry, Dr Hans-Armin Dieterich and Dr Venkateswar Jarugula

    Version of Record online : 7 MAR 2013, DOI: 10.1177/0091270010385934

  14. Aliskiren increases bradykinin and tissue kallikrein mRNA levels in the heart

    Clinical and Experimental Pharmacology and Physiology

    Volume 38, Issue 9, September 2011, Pages: 623–631, Duncan J Campbell, Yuan Zhang, Darren J Kelly, Richard E Gilbert, Davis J McCarthy, Wei Shi and Gordon K Smyth

    Version of Record online : 26 AUG 2011, DOI: 10.1111/j.1440-1681.2011.05572.x

  15. Pharmacokinetics, Safety, and Tolerability of the Novel Oral Direct Renin Inhibitor Aliskiren in Elderly Healthy Subjects

    The Journal of Clinical Pharmacology

    Volume 47, Issue 4, April 2007, Pages: 453–460, Dr Sujata Vaidyanathan, Ms Christine Reynolds, Dr Ching-Ming Yeh, Dr Marie-Noëlle Bizot, Dr Hans Armin Dieterich, Dr Dan Howard and Dr William P. Dole

    Version of Record online : 8 MAR 2013, DOI: 10.1177/0091270006297921

  16. Conformational Properties and Energetic Analysis of Aliskiren in Solution and Receptor Site

    Molecular Informatics

    Volume 30, Issue 11-12, December 2011, Pages: 973–985, Aggeliki Politi , Georgios Leonis, Haralambos Tzoupis , Dimitrios Ntountaniotis, Manthos G. Papadopoulos, Simona Golic Grdadolnik  and Thomas Mavromoustakos 

    Version of Record online : 1 DEC 2011, DOI: 10.1002/minf.201100077

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    Orange and apple juice greatly reduce the plasma concentrations of the OATP2B1 substrate aliskiren

    British Journal of Clinical Pharmacology

    Volume 71, Issue 5, May 2011, Pages: 718–726, Tuija Tapaninen, Pertti J. Neuvonen and Mikko Niemi

    Version of Record online : 11 APR 2011, DOI: 10.1111/j.1365-2125.2010.03898.x

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    Aliskiren Alone or in Combination With Hydrochlorothiazide in Patients With the Lower Ranges of Stage 2 Hypertension: The ACQUIRE Randomized Double-Blind Study

    The Journal of Clinical Hypertension

    Volume 12, Issue 12, December 2010, Pages: 917–926, Henry R. Black, Andreas Kribben, Fernando Aguirre Palacios, Mahendra Bijarnia, Annik K. Laflamme and Fabio Baschiera

    Version of Record online : 4 OCT 2010, DOI: 10.1111/j.1751-7176.2010.00378.x

  19. Pharmacokinetics and Pharmacodynamics of Aliskiren/Hydrochlorothiazide Single-Pill Combination Tablets and Free Combination of Aliskiren and Hydrochlorothiazide

    The Journal of Clinical Pharmacology

    Volume 52, Issue 5, May 2012, Pages: 645–655, Dr Jing-He Yan, Dr Venkateswar Jarugula, Dr Ron Sabo, Dr Cheraz Cherif Papst, Dr Jack Zhang and Dr William P. Dole

    Version of Record online : 7 MAR 2013, DOI: 10.1177/0091270011405499

  20. Influence of Body Weight and Gender on the Pharmacokinetics, Pharmacodynamics, and Antihypertensive Efficacy of Aliskiren

    The Journal of Clinical Pharmacology

    Volume 50, Issue 12, December 2010, Pages: 1358–1366, Dr Venkateswar Jarugula, Dr Ching-Ming Yeh, Dr Dan Howard, Dr Christopher Bush, Dr Deborah L. Keefe and Dr William P. Dole

    Version of Record online : 7 MAR 2013, DOI: 10.1177/0091270009359525