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There are 18804 results for: content related to: Induction of CYP3A by Ethanol in Multiple In Vitro and In Vivo Models

  1. You have free access to this content
    P-glycoprotein and cytochrome P450 3A act together in restricting the oral bioavailability of paclitaxel

    International Journal of Cancer

    Volume 132, Issue 10, 15 May 2013, Pages: 2439–2447, Jeroen J.M.A. Hendrikx, Jurjen S. Lagas, Hilde Rosing, Jan H.M. Schellens, Jos H. Beijnen and Alfred H. Schinkel

    Article first published online : 14 NOV 2012, DOI: 10.1002/ijc.27912

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    Dual effect of dexamethasone on CYP3A4 gene expression in human hepatocytes

    European Journal of Biochemistry

    Volume 268, Issue 24, December 2001, Pages: 6346–6358, Jean-Marc Pascussi, Lionel Drocourt, Sabine Gerbal-Chaloin, Jean-Michel Fabre, Patrick Maurel and Marie-José Vilarem

    Article first published online : 12 JAN 2002, DOI: 10.1046/j.0014-2956.2001.02540.x

  3. Functional Gene Variants of CYP3A4

    Clinical Pharmacology & Therapeutics

    Volume 96, Issue 3, September 2014, Pages: 340–348, A N Werk and I Cascorbi

    Article first published online : 13 JUN 2014, DOI: 10.1038/clpt.2014.129

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    Clinical implementation of pharmacogenetics in kidney transplantation: calcineurin inhibitors in the starting blocks

    British Journal of Clinical Pharmacology

    Volume 77, Issue 4, April 2014, Pages: 715–728, Laure Elens, Rachida Bouamar, Nauras Shuker, Dennis A. Hesselink, Teun van Gelder and Ron H. N. van Schaik

    Article first published online : 20 MAR 2014, DOI: 10.1111/bcp.12253

  5. Differential gene expression of CYP3A isoforms in equine liver and intestines

    Journal of Veterinary Pharmacology and Therapeutics

    Volume 35, Issue 6, December 2012, Pages: 588–595, E. TYDÉN, M. LÖFGREN, S. PEGOLO, F. CAPOLONGO, H. TJÄLVE and P. LARSSON

    Article first published online : 29 JAN 2012, DOI: 10.1111/j.1365-2885.2012.01379.x

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    Effects of cytochrome P450 3A (CYP3A) and the drug transporters P-glycoprotein (MDR1/ABCB1) and MRP2 (ABCC2) on the pharmacokinetics of lopinavir

    British Journal of Pharmacology

    Volume 160, Issue 5, July 2010, Pages: 1224–1233, RAB van Waterschoot, R ter Heine, E Wagenaar, CMM van der Kruijssen, RW Rooswinkel, ADR Huitema, JH Beijnen and AH Schinkel

    Article first published online : 22 MAR 2010, DOI: 10.1111/j.1476-5381.2010.00759.x

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    Expression of CYP3A in the Human Liver — Evidence that the Shift between CYP3A7 and CYP3A4 Occurs Immediately After Birth

    European Journal of Biochemistry

    Volume 247, Issue 2, July 1997, Pages: 625–634, Dan Lacroix, Michelle Sonnier, Arlette Moncion, Gérard Cheron and Thierry Cresteil

    Article first published online : 16 JUL 2004, DOI: 10.1111/j.1432-1033.1997.00625.x

  8. Pharmacogenetic Pathway Analysis of Docetaxel Elimination

    Clinical Pharmacology & Therapeutics

    Volume 85, Issue 2, February 2009, Pages: 155–163, SD Baker, J Verweij, GA Cusatis, RH van Schaik, S Marsh, SJ Orwick, RM Franke, S Hu, EG Schuetz, V Lamba, WA Messersmith, AC Wolff, MA Carducci and A Sparreboom

    Article first published online : 28 MAY 2008, DOI: 10.1038/clpt.2008.95

  9. The CYP3A4*18 Genotype in the Cytochrome P450 3A4 Gene, a Rapid Metabolizer of Sex Steroids, Is Associated With Low Bone Mineral Density

    Clinical Pharmacology & Therapeutics

    Volume 85, Issue 3, March 2009, Pages: 312–318, YS Kang, SY Park, CH Yim, HS Kwak, P Gajendrarao, N Krishnamoorthy, S-C Yun, KW Lee and KO Han

    Article first published online : 19 NOV 2008, DOI: 10.1038/clpt.2008.215

  10. In Vivo CYP3A4 Activity, CYP3A5 Genotype, and Hematocrit Predict Tacrolimus Dose Requirements and Clearance in Renal Transplant Patients

    Clinical Pharmacology & Therapeutics

    Volume 92, Issue 3, September 2012, Pages: 366–375, H de Jonge, H de Loor, K Verbeke, Y Vanrenterghem and D R Kuypers

    Article first published online : 8 AUG 2012, DOI: 10.1038/clpt.2012.109

  11. Enzyme- and Transporter-Mediated Drug Interactions with Small Molecule Tyrosine Kinase Inhibitors

    Journal of Pharmaceutical Sciences

    Volume 103, Issue 12, December 2014, Pages: 3810–3833, Jie Shao, John S. Markowitz, Di Bei and Guohua An

    Article first published online : 10 OCT 2014, DOI: 10.1002/jps.24113

  12. Mechanism of Efavirenz Influence on Methadone Pharmacokinetics and Pharmacodynamics

    Clinical Pharmacology & Therapeutics

    Volume 91, Issue 4, April 2012, Pages: 673–684, E D Kharasch, D Whittington, D Ensign, C Hoffer, P S Bedynek, S Campbell, K Stubbert, A Crafford, A London and T Kim

    Article first published online : 7 MAR 2012, DOI: 10.1038/clpt.2011.276

  13. CYP3A4 variant alleles in white individuals with low CYP3A4 enzyme activity

    Clinical Pharmacology & Therapeutics

    Volume 71, Issue 3, March 2002, Pages: 196–204, Elena García-Martín, Carmen Martínez, Rosa M. Pizarro, Francisco J. García-Gamito, Harriet Gullsten, Hannu Raunio and José A. G. Agúndez

    Article first published online : 22 MAR 2002, DOI: 10.1067/mcp.2002.121371

  14. An integrated pharmacokinetic model for the influence of CYP3A4 expression on the in vivo disposition of lopinavir and its modulation by ritonavir

    Journal of Pharmaceutical Sciences

    Volume 100, Issue 6, June 2011, Pages: 2508–2515, Rob ter Heine, Robert A. B. Van Waterschoot, Ron J. Keizer, Jos H. Beijnen, Alfred H. Schinkel and Alwin D. R. Huitema

    Article first published online : 29 DEC 2010, DOI: 10.1002/jps.22457

  15. Clinical pharmacogenetics implementation consortium (CPIC) guidelines for CYP3A5 genotype and tacrolimus dosing

    Clinical Pharmacology & Therapeutics

    Accepted manuscript online: 18 MAR 2015, Kelly A. Birdwell, Brian Decker, Julia M. Barbarino, Josh F. Peterson, C. Michael Stein, Wolfgang Sadee, Danxin Wang, Alexander A. Vinks, Yijing He, Jesse J. Swen, J. Steven Leeder, R.H.N. van Schaik, Kenneth E. Thummel, Teri E. Klein, Kelly E. Caudle and Iain A.M. MacPhee

    DOI: 10.1002/cpt.113

  16. Sensitivity of Intravenous and Oral Alfentanil and Pupillary Miosis as Minimally Invasive and Noninvasive Probes for Hepatic and First-Pass CYP3A Activity

    The Journal of Clinical Pharmacology

    Volume 45, Issue 10, October 2005, Pages: 1187–1197, Evan D. Kharasch, Alysa Walker, Christine Hoffer and Pamela Sheffels

    Article first published online : 8 MAR 2013, DOI: 10.1177/0091270005280077

  17. Kidney Transplant Recipients Carrying the CYP3A4*22 Allelic Variant Have Reduced Tacrolimus Clearance and Often Reach Supratherapeutic Tacrolimus Concentrations

    American Journal of Transplantation

    Volume 15, Issue 3, March 2015, Pages: 800–805, N. Pallet, A.-S. Jannot, M. El Bahri, I. Etienne, M. Buchler, B. H. de Ligny, G. Choukroun, C. Colosio, A. Thierry, C. Vigneau, B. Moulin, Y. Le Meur, A.-E. Heng, J.-F. Subra, C. Legendre, P. Beaune, C. Alberti, M. A. Loriot and E. Thervet

    Article first published online : 14 JAN 2015, DOI: 10.1111/ajt.13059

  18. Plasma 4β-Hydroxycholesterol: An Endogenous CYP3A Metric?

    Clinical Pharmacology & Therapeutics

    Volume 86, Issue 2, August 2009, Pages: 147–153, D Tomalik-Scharte, D Lütjohann, O Doroshyenko, D Frank, A Jetter and U Fuhr

    Article first published online : 20 MAY 2009, DOI: 10.1038/clpt.2009.72

  19. Ontogeny of CYP3A and P-Glycoprotein in the Liver and the Small Intestine of the Göttingen Minipig: An Immunohistochemical Evaluation

    Basic & Clinical Pharmacology & Toxicology

    Volume 114, Issue 5, May 2014, Pages: 387–394, Els Van Peer, Evy Verbueken, Moayad Saad, Christophe Casteleyn, Chris Van Ginneken and Steven Van Cruchten

    Article first published online : 13 DEC 2013, DOI: 10.1111/bcpt.12173

  20. A mechanistic physiologically based pharmacokinetic-enzyme turnover model involving both intestine and liver to predict CYP3A induction-mediated drug–drug interactions

    Journal of Pharmaceutical Sciences

    Volume 102, Issue 8, August 2013, Pages: 2819–2836, Haifang Guo, Can Liu, Jia Li, Mian Zhang, Mengyue Hu, Ping Xu, Li Liu and Xiaodong Liu

    Article first published online : 11 JUN 2013, DOI: 10.1002/jps.23613