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There are 4737 results for: content related to: Effect of Alcohol on Drug Efflux Protein and Drug Metabolic Enzymes in U937 Macrophages

  1. Pharmacogenetics-Based Population Pharmacokinetic Analysis of Efavirenz in HIV-1-Infected Individuals

    Clinical Pharmacology & Therapeutics

    Volume 85, Issue 5, May 2009, Pages: 485–494, M Arab-Alameddine, J Di Iulio, T Buclin, M Rotger, R Lubomirov, M Cavassini, A Fayet, LA Décosterd, CB Eap, J Biollaz, A Telenti and C Csajka

    Version of Record online : 18 FEB 2009, DOI: 10.1038/clpt.2008.271

  2. You have free access to this content
    CYP2B6 (c.516G[RIGHTWARDS ARROW]T) and CYP2A6 (*9B and/or *17) polymorphisms are independent predictors of efavirenz plasma concentrations in HIV-infected patients

    British Journal of Clinical Pharmacology

    Volume 67, Issue 4, April 2009, Pages: 427–436, Awewura Kwara, Margaret Lartey, Kwamena W. Sagoe, Naser L. Rzek and Michael H. Court

    Version of Record online : 21 JAN 2009, DOI: 10.1111/j.1365-2125.2009.03368.x

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    Pharmacogenetics of plasma efavirenz exposure in HIV-infected adults and children in South Africa

    British Journal of Clinical Pharmacology

    Volume 80, Issue 1, July 2015, Pages: 146–156, Phumla Z. Sinxadi, Paul D. Leger, Helen M. McIlleron, Peter J. Smith, Joel A. Dave, Naomi S Levitt, Gary Maartens and David W. Haas

    Version of Record online : 28 MAY 2015, DOI: 10.1111/bcp.12590

  4. You have full text access to this OnlineOpen article
    Pharmacokinetic and Pharmacodynamic Comparison of Once-Daily Efavirenz (400 mg vs. 600 mg) in Treatment-Naïve HIV-Infected Patients: Results of the ENCORE1 Study

    Clinical Pharmacology & Therapeutics

    Volume 98, Issue 4, October 2015, Pages: 406–416, L Dickinson, J Amin, L Else, M Boffito, D Egan, A Owen, S Khoo, D Back, C Orrell, A Clarke, M Losso, P Phanuphak, D Carey, DA Cooper, S Emery and R Puls2, on behalf of the ENCORE1 Study Group

    Version of Record online : 14 JUL 2015, DOI: 10.1002/cpt.156

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    Metabolic capabilities of cytochrome P450 enzymes in Chinese liver microsomes compared with those in Caucasian liver microsomes

    British Journal of Clinical Pharmacology

    Volume 73, Issue 2, February 2012, Pages: 268–284, Junling Yang, Minxia M. He, Wei Niu, Steven A. Wrighton, Li Li, Yang Liu and Chuan Li

    Version of Record online : 6 JAN 2012, DOI: 10.1111/j.1365-2125.2011.04076.x

  6. Determinants of the rate of nicotine metabolism and effects on smoking behavior

    Clinical Pharmacology & Therapeutics

    Volume 80, Issue 4, October 2006, Pages: 319–330, Elaine Johnstone, Neal Benowitz, Anna Cargill, Robyn Jacob, Lesley Hinks, Ian Day, Mike Murphy and Robert Walton

    Version of Record online : 22 OCT 2006, DOI: 10.1016/j.clpt.2006.06.011

  7. Population pharmacogenetic-based pharmacokinetic modeling of efavirenz, 7-hydroxy- and 8-hydroxyefavirenz

    The Journal of Clinical Pharmacology

    Volume 54, Issue 1, January 2014, Pages: 87–96, A.M. Abdelhady, Z. Desta, F. Jiang, C.W. Yeo, J.G. Shin and B.R. Overholser

    Version of Record online : 19 NOV 2013, DOI: 10.1002/jcph.208

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    Identification of the human cytochrome P450 enzymes involved in the in vitro metabolism of artemisinin

    British Journal of Clinical Pharmacology

    Volume 48, Issue 4, October 1999, Pages: 528–535, Svensson and Ashton

    Version of Record online : 24 DEC 2001, DOI: 10.1046/j.1365-2125.1999.00044.x

  9. Effect of Rifampicin and CYP2B6 Genotype on Long-Term Efavirenz Autoinduction and Plasma Exposure in HIV Patients With or Without Tuberculosis

    Clinical Pharmacology & Therapeutics

    Volume 90, Issue 3, September 2011, Pages: 406–413, E Ngaimisi, S Mugusi, O Minzi, P Sasi, K-D Riedel, A Suda, N Ueda, M Janabi, F Mugusi, W E Haefeli, L Bertilsson, J Burhenne and E Aklillu

    Version of Record online : 3 AUG 2011, DOI: 10.1038/clpt.2011.129

  10. Selective Induction of Human Hepatic Cytochromes P450 2B6 and 3A4 by Metamizole

    Clinical Pharmacology & Therapeutics

    Volume 82, Issue 3, September 2007, Pages: 265–274, T Saussele, O Burk, J K Blievernicht, K Klein, A Nussler, N Nussler, J G Hengstler, M Eichelbaum, M Schwab and U M Zanger

    Version of Record online : 7 MAR 2007, DOI: 10.1038/sj.clpt.6100138

  11. Cytochrome P450 Polymorphisms

    Standard Article

    Encyclopedia of Drug Metabolism and Interactions

    Ulrich M. Zanger

    Published Online : 31 JAN 2012, DOI: 10.1002/9780470921920.edm009

  12. American Society for Clinical Pharmacology and Therapeutics

    Clinical Pharmacology & Therapeutics

    Volume 101, Issue S1, February 2017, Pages: S5–S99,

    Version of Record online : 13 JAN 2017, DOI: 10.1002/cpt.570

  13. Pharmacokinetics of Efavirenz When Co-administered With Rifampin in TB/HIV Co-infected Patients: Pharmacogenetic Effect of CYP2B6 Variation

    The Journal of Clinical Pharmacology

    Volume 48, Issue 9, September 2008, Pages: 1032–1040, Dr Awewura Kwara, Dr Margaret Lartey, Mr Kwamena W. Sagoe, Dr Fafa Xexemeku, Dr Ernest Kenu, Dr Joseph Oliver-Commey, Dr Vincent Boima, Mr Augustine Sagoe, Dr Isaac Boamah, Mr David J. Greenblatt and Dr Michael H. Court

    Version of Record online : 7 MAR 2013, DOI: 10.1177/0091270008321790

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    Phenobarbital increases monkey in vivo nicotine disposition and induces liver and brain CYP2B6 protein

    British Journal of Pharmacology

    Volume 148, Issue 6, July 2006, Pages: 786–794, Anna M Lee, Sharon Miksys and Rachel F Tyndale

    Version of Record online : 29 JAN 2009, DOI: 10.1038/sj.bjp.0706787

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    New potent and selective cytochrome P450 2B6 (CYP2B6) inhibitors based on three-dimensional quantitative structure-activity relationship (3D-QSAR) analysis

    British Journal of Pharmacology

    Volume 150, Issue 7, April 2007, Pages: 932–942, L E Korhonen, M Turpeinen, M Rahnasto, C Wittekindt, A Poso, O Pelkonen, H Raunio and R O Juvonen

    Version of Record online : 29 JAN 2009, DOI: 10.1038/sj.bjp.0707173

  16. PhRMA White Paper on ADME Pharmacogenomics

    The Journal of Clinical Pharmacology

    Volume 48, Issue 7, July 2008, Pages: 849–889, Dr J. Andrew Williams, Dr Tommy Andersson, Dr Tommy B. Andersson, Dr Rebecca Blanchard, Dr Martin Otto Behm, Dr Nadine Cohen, Dr Timi Edeki, Dr Monique Franc, Dr Kathleen M. Hillgren, Dr Keith J. Johnson, Dr David A. Katz, Dr Mark N. Milton, Dr Bernard P. Murray, Dr Joseph W. Polli, Dr Deb Ricci, Dr Lisa A. Shipley, Dr Subrahmanyam Vangala and Dr Steven A. Wrighton

    Version of Record online : 7 MAR 2013, DOI: 10.1177/0091270008319329

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    The combined impact of CYP2C19 and CYP2B6 pharmacogenetics on cyclophosphamide bioactivation

    British Journal of Clinical Pharmacology

    Volume 70, Issue 6, December 2010, Pages: 844–853, Nuala A. Helsby, Chung-Yee Hui, Michael A. Goldthorpe, Janet K. Coller, May Ching Soh, Peter J. Gow, Janak Z. De Zoysa and Malcolm D. Tingle

    Version of Record online : 11 NOV 2010, DOI: 10.1111/j.1365-2125.2010.03789.x

  18. You have full text access to this OnlineOpen article
    Towards a Best Practice Approach in PBPK Modeling: Case Example of Developing a Unified Efavirenz Model Accounting for Induction of CYPs 3A4 and 2B6

    CPT: Pharmacometrics & Systems Pharmacology

    Volume 5, Issue 7, July 2016, Pages: 367–376, A Ke, Z Barter, K Rowland-Yeo and L Almond

    Version of Record online : 20 JUL 2016, DOI: 10.1002/psp4.12088

  19. Single Heteroatom Substitutions in the Efavirenz Oxazinone Ring Impact Metabolism by CYP2B6


    Volume 11, Issue 23, December 6, 2016, Pages: 2630–2637, Philip M. Cox and Dr. Namandjé N. Bumpus

    Version of Record online : 10 NOV 2016, DOI: 10.1002/cmdc.201600519

  20. Haplotype structure and allele frequencies of CYP2B6 in Spaniards and Central Americans

    Fundamental & Clinical Pharmacology

    Volume 24, Issue 2, April 2010, Pages: 247–253, Izaskun Arenaz, Jorge Vicente, Ana Fanlo, Patricia Vásquez, Juan Carlos Medina, Blanca Conde, Fabricio González-Andrade and Blanca Sinués

    Version of Record online : 14 AUG 2009, DOI: 10.1111/j.1472-8206.2009.00753.x