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There are 50828 results for: content related to: Safety and efficacy of protease-activated receptor-1 antagonists in patients with coronary artery disease: a meta-analysis of randomized clinical trials

  1. Interrelationship of Thrombin and Platelets: The Protease Activated Receptor-1

    Therapeutic Advances in Thrombosis, Second Edition

    Matthew E. Wiisanen, David J. Moliterno, Pages: 71–86, 2012

    Published Online : 3 OCT 2012, DOI: 10.1002/9781118410875.ch6

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    Protease activated receptor-1 antagonist ameliorates the clinical symptoms of experimental autoimmune encephalomyelitis via inhibiting breakdown of blood–brain barrier

    Journal of Neurochemistry

    Volume 135, Issue 3, November 2015, Pages: 577–588, Ha Neui Kim, Yu Ri Kim, Sung Min Ahn, Sun Kyung Lee, Hwa Kyoung Shin and Byung Tae Choi

    Version of Record online : 22 SEP 2015, DOI: 10.1111/jnc.13285

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    Vascular PAR-1: Activity and Antagonism

    Cardiovascular Therapeutics

    Volume 29, Issue 6, December 2011, Pages: 349–361, Ninian N. Lang, Ingibjörg J. Guðmundsdóttir and David E. Newby

    Version of Record online : 27 MAY 2010, DOI: 10.1111/j.1755-5922.2010.00140.x

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    Antiplatelet therapy: thrombin receptor antagonists

    British Journal of Clinical Pharmacology

    Volume 72, Issue 4, October 2011, Pages: 658–671, Antonio Tello-Montoliu, Salvatore D. Tomasello, Masafumi Ueno and Dominick J. Angiolillo

    Version of Record online : 9 SEP 2011, DOI: 10.1111/j.1365-2125.2010.03884.x

  5. Thrombin Receptor Antagonists

    Antiplatelet Therapy in Cardiovascular Disease

    Flávio de Souza Brito, Pierluigi Tricoci, Pages: 198–205, 2014

    Published Online : 28 MAR 2014, DOI: 10.1002/9781118493984.ch24

  6. Emerging Antiplatelet Therapy for Coronary Artery Disease and Acute Coronary Syndrome

    Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy

    Volume 32, Issue 3, March 2012, Pages: 244–273, Kathleen A. Packard, Jennifer A. Campbell, Jon T. Knezevich and Estella M. Davis

    Version of Record online : 28 FEB 2012, DOI: 10.1002/j.1875-9114.2012.01021.x

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    Protease-activated receptor 2, rather than protease-activated receptor 1, contributes to the aggressive properties of synovial fibroblasts in rheumatoid arthritis

    Arthritis & Rheumatism

    Volume 64, Issue 1, January 2012, Pages: 88–98, Meilang Xue, Yee-Ka Agnes Chan, Kaitlin Shen, Suat Dervish, Lyn March, Philip N. Sambrook and Christopher J. Jackson

    Version of Record online : 29 DEC 2011, DOI: 10.1002/art.33323

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    Proteinases and signalling: pathophysiological and therapeutic implications via PARs and more

    British Journal of Pharmacology

    Volume 153, Issue S1, March 2008, Pages: S263–S282, R Ramachandran and M D Hollenberg

    Version of Record online : 29 JAN 2009, DOI: 10.1038/sj.bjp.0707507

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    Modulation of PAR1 signalling by benzimidazole compounds

    British Journal of Pharmacology

    Volume 167, Issue 1, September 2012, Pages: 80–94, S Asteriti, S Daniele, F Porchia, MT Dell'Anno, A Fazzini, I Pugliesi, ML Trincavelli, S Taliani, C Martini, MR Mazzoni and A Gilchrist

    Version of Record online : 3 AUG 2012, DOI: 10.1111/j.1476-5381.2012.01974.x

  10. Antiplatelet Agents

    Standard Article

    Burger's Medicinal Chemistry and Drug Discovery

    Samuel Chackalamannil

    Published Online : 15 SEP 2010, DOI: 10.1002/0471266949.bmc175

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    RWJ-58259: A Selective Antagonist of Protease Activated Receptor-1

    Cardiovascular Drug Reviews

    Volume 21, Issue 4, December 2003, Pages: 313–326, Bruce P. Damiano, Claudia K. Derian, Bruce E. Maryanoff, Han-Cheng Zhang and Patricia Andrade Gordon

    Version of Record online : 7 JUN 2006, DOI: 10.1111/j.1527-3466.2003.tb00124.x

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    Thrombin Inhibits NMDA-Mediated Nociceptive activity in the Mouse: Possible Mediation by Endothelin

    The Journal of Physiology

    Volume 549, Issue 3, June 2003, Pages: 903–917, Ming Fang, Katalin J. Kovács, Lauralei L. Fisher and Alice A. Larson

    Version of Record online : 16 JUL 2004, DOI: 10.1113/jphysiol.2002.036384

  13. You have full text access to this OnlineOpen article
    Protease-activated receptor (PAR)-2 is required for PAR-1 signalling in pulmonary fibrosis

    Journal of Cellular and Molecular Medicine

    Volume 19, Issue 6, June 2015, Pages: 1346–1356, Cong Lin, Jan von der Thüsen, Joost Daalhuisen, Marieke ten Brink, Bruno Crestani, Tom van der Poll, Keren Borensztajn and C. Arnold Spek

    Version of Record online : 16 FEB 2015, DOI: 10.1111/jcmm.12520

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    Abstracts

    Journal of Thrombosis and Haemostasis

    Volume 13, Issue S2, June 2015, Pages: 1–997,

    Version of Record online : 3 JUN 2015, DOI: 10.1111/jth.12993

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    Effect of Vorapaxar Alone and in Combination with Aspirin on Bleeding Time and Platelet Aggregation in Healthy Adult Subjects

    Clinical and Translational Science

    Volume 9, Issue 4, August 2016, Pages: 221–227, WK Kraft, JH Gilmartin, DL Chappell, F Gheyas, BM Walker, S Nagalla, UP Naik, JC Horrow, RE Wrishko, S Zhang and MS Anderson

    Version of Record online : 15 JUN 2016, DOI: 10.1111/cts.12405

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    Procoagulant signalling mechanisms in lung inflammation and fibrosis: novel opportunities for pharmacological intervention?

    British Journal of Pharmacology

    Volume 153, Issue S1, March 2008, Pages: S367–S378, R C Chambers

    Version of Record online : 29 JAN 2009, DOI: 10.1038/sj.bjp.0707603

  17. The Effect of Multiple Doses of Ketoconazole or Rifampin on the Single- and Multiple-Dose Pharmacokinetics of Vorapaxar

    The Journal of Clinical Pharmacology

    Volume 53, Issue 5, May 2013, Pages: 540–549, Teddy Kosoglou, Paul Statkevich, Bharath Kumar, Fengjuan Xuan, James E. Schiller, Amy O. Johnson-Levonas, Sophia Young and David L. Cutler

    Version of Record online : 20 FEB 2013, DOI: 10.1002/jcph.20

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    Safety and efficacy of targeting platelet proteinase-activated receptors in combination with existing anti-platelet drugs as antithrombotics in mice

    British Journal of Pharmacology

    Volume 166, Issue 7, August 2012, Pages: 2188–2197, H Lee, SA Sturgeon, JK Mountford, SP Jackson and JR Hamilton

    Version of Record online : 9 JUL 2012, DOI: 10.1111/j.1476-5381.2012.01944.x

  19. Vorapaxar: From Lead Identification to FDA Approval

    Lead Generation: Methods, Strategies, and Case Studies

    Samuel Chackalamannil, Mariappan Chelliah, Pages: 547–574, 2016

    Published Online : 13 MAY 2016, DOI: 10.1002/9783527677047.ch19

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    Proteinase-activated receptor-1 (PAR-1) activation contracts the isolated human renal artery in vitro

    British Journal of Pharmacology

    Volume 139, Issue 1, May 2003, Pages: 21–27, Michele Tognetto, Michael R D'Andrea, Marcello Trevisani, Remo Guerrini, Severo Salvadori, Lorella Spisani, Carlo Daniele, Patricia Andrade-Gordon, Pierangelo Geppetti and Selena Harrison

    Version of Record online : 29 JAN 2009, DOI: 10.1038/sj.bjp.0705215