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There are 26745 results for: content related to: Increased platelet activation and thrombosis in transgenic mice expressing constitutively active P2Y 12

  1. You have free access to this content
    P2Y12 protects platelets from apoptosis via PI3k-dependent Bak/Bax inactivation

    Journal of Thrombosis and Haemostasis

    Volume 11, Issue 1, January 2013, Pages: 149–160, S. ZHANG, J. YE, Y. ZHANG, X. XU, J. LIU, S. H. ZHANG, S. P. KUNAPULI and Z. DING

    Article first published online : 27 JAN 2013, DOI: 10.1111/jth.12063

  2. You have free access to this content
    Human target validation of phosphoinositide 3-kinase (PI3K)β: effects on platelets and insulin sensitivity, using AZD6482 a novel PI3Kβ inhibitor

    Journal of Thrombosis and Haemostasis

    Volume 10, Issue 10, October 2012, Pages: 2127–2136, S. NYLANDER, B. KULL, J. A. BJÖRKMAN, J. C. ULVINGE, N. OAKES, B. M. EMANUELSSON, M. ANDERSSON, T. SKÄRBY, T. INGHARDT, O. FJELLSTRÖM and D. GUSTAFSSON

    Article first published online : 1 OCT 2012, DOI: 10.1111/j.1538-7836.2012.04898.x

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    Gi-dependent and -independent mechanisms downstream of the P2Y12 ADP-receptor

    Journal of Thrombosis and Haemostasis

    Volume 2, Issue 1, January 2004, Pages: 135–146, C. Soulet, V. Sauzeau, M. Plantavid, J. M. Herbert, P. Pacaud, B. Payrastre and P. Savi

    Article first published online : 9 JAN 2004, DOI: 10.1111/j.1538-7836.2004.00556.x

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    Modified diadenosine tetraphosphates with dual specificity for P2Y1 and P2Y12 are potent antagonists of ADP-induced platelet activation

    Journal of Thrombosis and Haemostasis

    Volume 10, Issue 12, December 2012, Pages: 2573–2580, H. CHANG, I. B. YANACHKOV, E. J. DIX, Y. F. LI, M. R. BARNARD, G. E. WRIGHT, A. D. MICHELSON and A. L. FRELINGER III

    Article first published online : 12 DEC 2012, DOI: 10.1111/jth.12035

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    A Gi-independent mechanism mediating Akt phosphorylation in platelets

    Journal of Thrombosis and Haemostasis

    Volume 8, Issue 9, September 2010, Pages: 2032–2041, B. XIANG, G. ZHANG, J. LIU, A. J. MORRIS, S. S. SMYTH, T. K. GARTNER and Z. LI

    Article first published online : 24 JUN 2010, DOI: 10.1111/j.1538-7836.2010.03969.x

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    In the presence of strong P2Y12 receptor blockade, aspirin provides little additional inhibition of platelet aggregation

    Journal of Thrombosis and Haemostasis

    Volume 9, Issue 3, March 2011, Pages: 552–561, P. C. J. ARMSTRONG, P. D. LEADBEATER, M. V. CHAN, N. S. KIRKBY, J. A. JAKUBOWSKI, J. A. MITCHELL and T. D. WARNER

    Article first published online : 1 MAR 2011, DOI: 10.1111/j.1538-7836.2010.04160.x

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    Ticagrelor binds to human P2Y12 independently from ADP but antagonizes ADP-induced receptor signaling and platelet aggregation

    Journal of Thrombosis and Haemostasis

    Volume 7, Issue 9, September 2009, Pages: 1556–1565, J. J. J. VAN GIEZEN, L. NILSSON, P. BERNTSSON, B.-M. WISSING, F. GIORDANETTO, W. TOMLINSON and P. J. GREASLEY

    Article first published online : 23 JUN 2009, DOI: 10.1111/j.1538-7836.2009.03527.x

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    Safety and efficacy of protease-activated receptor-1 antagonists in patients with coronary artery disease: a meta-analysis of randomized clinical trials

    Journal of Thrombosis and Haemostasis

    Volume 10, Issue 10, October 2012, Pages: 2006–2015, D. CAPODANNO, D. L. BHATT, S. GOTO, M. L. O’DONOGHUE, D. J. MOLITERNO, C. TAMBURINO and D. J. ANGIOLILLO

    Article first published online : 1 OCT 2012, DOI: 10.1111/j.1538-7836.2012.04869.x

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    Potentiation of clopidogrel active metabolite formation by rifampicin leads to greater P2Y12 receptor blockade and inhibition of platelet aggregation after clopidogrel

    Journal of Thrombosis and Haemostasis

    Volume 8, Issue 8, August 2010, Pages: 1820–1827, H. M. JUDGE, S. B. PATIL, R. J. BUCKLAND, J. A. JAKUBOWSKI and R. F. STOREY

    Article first published online : 21 MAY 2010, DOI: 10.1111/j.1538-7836.2010.03925.x

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    Rapid resensitization of purinergic receptor function in human platelets

    Journal of Thrombosis and Haemostasis

    Volume 6, Issue 8, August 2008, Pages: 1393–1404, S. J. MUNDELL, J. F. BARTON, M. B. MAYO-MARTIN, A. R. HARDY and A. W. POOLE

    Article first published online : 28 MAY 2008, DOI: 10.1111/j.1538-7836.2008.03039.x

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    Reciprocal regulation of platelet responses to P2Y and thromboxane receptor activation

    Journal of Thrombosis and Haemostasis

    Volume 6, Issue 3, March 2008, Pages: 534–543, J. F. BARTON, A. R. HARDY, A. W. POOLE and S. J. MUNDELL

    Article first published online : 10 DEC 2007, DOI: 10.1111/j.1538-7836.2007.02866.x

  12. You have free access to this content
    Impaired platelet function in a patient with P2Y12 deficiency caused by a mutation in the translation initiation codon

    Journal of Thrombosis and Haemostasis

    Volume 3, Issue 10, October 2005, Pages: 2315–2323, M. SHIRAGA, S. MIYATA, H. KATO, H. KASHIWAGI, S. HONDA, Y. KURATA, Y. TOMIYAMA and Y. KANAKURA

    Article first published online : 29 SEP 2005, DOI: 10.1111/j.1538-7836.2005.01554.x

  13. You have free access to this content
    (N)-methanocarba-2MeSADP (MRS2365) is a subtype-specific agonist that induces rapid desensitization of the P2Y1 receptor of human platelets

    Journal of Thrombosis and Haemostasis

    Volume 4, Issue 4, April 2006, Pages: 861–868, D. M. BOURDON, S. K. MAHANTY, K. A. JACOBSON, J. L. BOYER and T. K. HARDEN

    Article first published online : 15 MAR 2006, DOI: 10.1111/j.1538-7836.2006.01866.x

  14. You have free access to this content
    Adenine triphosphate nucleotides are antagonists at the P2Y12 receptor

    Journal of Thrombosis and Haemostasis

    Volume 2, Issue 11, November 2004, Pages: 1980–1988, G. Kauffenstein, B. Hechler, J.-P. Cazenave and C. Gachet

    Article first published online : 6 OCT 2004, DOI: 10.1111/j.1538-7836.2004.00926.x

  15. You have full text access to this OnlineOpen article
    Aspirin has little additional anti-platelet effect in healthy volunteers receiving prasugrel

    Journal of Thrombosis and Haemostasis

    Volume 9, Issue 10, October 2011, Pages: 2050–2056, P. D. M. LEADBEATER, N. S. KIRKBY, S. THOMAS, A.-R. DHANJI, A. T. TUCKER, G. L. MILNE, J. A. MITCHELL and T. D. WARNER

    Article first published online : 29 SEP 2011, DOI: 10.1111/j.1538-7836.2011.04450.x

  16. You have free access to this content
    Succinate independently stimulates full platelet activation via cAMP and phosphoinositide 3-kinase-β signaling

    Journal of Thrombosis and Haemostasis

    Volume 9, Issue 2, February 2011, Pages: 361–372, C. HÖGBERG, O. GIDLÖF, C. TAN, S. SVENSSON, J. NILSSON-ÖHMAN, D. ERLINGE and B. OLDE

    Article first published online : 27 JAN 2011, DOI: 10.1111/j.1538-7836.2010.04158.x

  17. You have free access to this content
    P2Y12 receptor-mediated potentiation of thrombin-induced thromboxane A2 generation in platelets occurs through regulation of Erk1/2 activation

    Journal of Thrombosis and Haemostasis

    Volume 4, Issue 3, March 2006, Pages: 638–647, H. SHANKAR, A. GARCIA, J. PRABHAKAR, S. KIM and S. P. KUNAPULI

    Article first published online : 6 FEB 2006, DOI: 10.1111/j.1538-7836.2006.01789.x

  18. You have free access to this content
    A differential role of the platelet ADP receptors P2Y1 and P2Y12 in Rac activation

    Journal of Thrombosis and Haemostasis

    Volume 3, Issue 10, October 2005, Pages: 2296–2306, C. SOULET, B. HECHLER, M.-P. GRATACAP, M. PLANTAVID, S. OFFERMANNS, C. GACHET and B. PAYRASTRE

    Article first published online : 29 SEP 2005, DOI: 10.1111/j.1538-7836.2005.01588.x

  19. You have free access to this content
    Quantification of ADP and ATP receptor expression in human platelets

    Journal of Thrombosis and Haemostasis

    Volume 1, Issue 2, February 2003, Pages: 330–336, L. Wang, O. Östberg, A-K Wihlborg, H. Brogren, S. Jern and D. Erlinge

    Article first published online : 7 FEB 2003, DOI: 10.1046/j.1538-7836.2003.00070.x

  20. You have free access to this content
    Inhibition of the platelet P2Y12 receptor for adenosine diphosphate potentiates the antiplatelet effect of prostacyclin

    Journal of Thrombosis and Haemostasis

    Volume 5, Issue 3, March 2007, Pages: 577–582, M. CATTANEO and A. LECCHI

    Article first published online : 21 FEB 2007, DOI: 10.1111/j.1538-7836.2007.02356.x

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    Corrigendum

    Vol. 5, Issue 5, 1094, Article first published online: 16 APR 2007