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There are 4690 results for: content related to: A Calibrated Human PBPK Model for Benzene Inhalation with Urinary Bladder and Bone Marrow Compartments

  1. American Society for Clinical Pharmacology and Therapeutics

    Clinical Pharmacology & Therapeutics

    Volume 101, Issue S1, February 2017, Pages: S5–S99,

    Version of Record online : 13 JAN 2017, DOI: 10.1002/cpt.570

  2. American Society for Clinical Pharmacology and Therapeutics

    Clinical Pharmacology & Therapeutics

    Volume 99, Issue S1, February 2016, Pages: S5–S107,

    Version of Record online : 24 JAN 2016, DOI: 10.1002/cpt.310

  3. Physiologically Based Pharmacokinetic Modeling

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    Pharmaceutical Sciences Encyclopedia

    Harvey J. Clewell, Micaela B. Reddy, Thierry Lave and Melvin E. Andersen

    Published Online : 15 MAR 2010, DOI: 10.1002/9780470571224.pse065

  4. Physiologically based pharmacokinetic modeling in drug discovery and development: A pharmaceutical industry perspective

    Clinical Pharmacology & Therapeutics

    Volume 97, Issue 3, March 2015, Pages: 247–262, HM Jones, Y Chen, C Gibson, T Heimbach, N Parrott, SA Peters, J Snoeys, VV Upreti, M Zheng and SD Hall

    Version of Record online : 9 JAN 2015, DOI: 10.1002/cpt.37

  5. The Use of PBPK Models to Inform Human Health Risk Assessment: Case Study on Perchlorate and Radioiodide Human Lifestage Models

    Risk Analysis

    Volume 34, Issue 2, February 2014, Pages: 356–366, Eva D. McLanahan, Paul White, Lynn Flowers and Paul M. Schlosser

    Version of Record online : 31 JUL 2013, DOI: 10.1111/risa.12101

  6. Physiologically Based Pharmacokinetic (PBPK) Modeling: Usefulness and Applications

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    Encyclopedia of Drug Metabolism and Interactions

    Han-Joo Maeng, Edwin C. Y. Chow, Jianghong Fan and K. Sandy Pang

    Published Online : 31 JAN 2012, DOI: 10.1002/9780470921920.edm036

  7. You have full text access to this OnlineOpen article
    Physiologically Based Pharmacokinetic Model Qualification and Reporting Procedures for Regulatory Submissions: A Consortium Perspective

    Clinical Pharmacology & Therapeutics

    Mohamad Shebley, Punam Sandhu, Arian Emami Riedmaier, Masoud Jamei, Rangaraj Narayanan, Aarti Patel, Sheila Annie Peters, Venkatesh Pilla Reddy, Ming Zheng, Loeckie de Zwart, Maud Beneton, Francois Bouzom, Jun Chen, Yuan Chen, Yumi Cleary, Christiane Collins, Gemma L. Dickinson, Nassim Djebli, Heidi J. Einolf, Iain Gardner, Felix Huth, Faraz Kazmi, Feras Khalil, Jing Lin, Aleksandrs Odinecs, Chirag Patel, Haojing Rong, Edgar Schuck, Pradeep Sharma, Shu-Pei Wu, Yang Xu, Shinji Yamazaki, Kenta Yoshida and Malcolm Rowland

    Version of Record online : 2 FEB 2018, DOI: 10.1002/cpt.1013

  8. Mathematical modeling and simulation in animal health – Part II: principles, methods, applications, and value of physiologically based pharmacokinetic modeling in veterinary medicine and food safety assessment

    Journal of Veterinary Pharmacology and Therapeutics

    Volume 39, Issue 5, October 2016, Pages: 421–438, Z. Lin, R. Gehring, J. P. Mochel, T. Lavé and J. E. Riviere

    Version of Record online : 17 APR 2016, DOI: 10.1111/jvp.12311

  9. Physiologically based pharmacokinetic modeling in regulatory decision-making at the European Medicines Agency

    Clinical Pharmacology & Therapeutics

    Volume 102, Issue 1, July 2017, Pages: 98–105, E Luzon, K Blake, S Cole, A Nordmark, C Versantvoort and E Gil Berglund

    Version of Record online : 26 DEC 2016, DOI: 10.1002/cpt.539

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    Basic Concepts in Physiologically Based Pharmacokinetic Modeling in Drug Discovery and Development

    CPT: Pharmacometrics & Systems Pharmacology

    Volume 2, Issue 8, August 2013, Pages: 1–12, HM Jones and K Rowland-Yeo

    Version of Record online : 14 AUG 2013, DOI: 10.1038/psp.2013.41

  11. Applications of Physiologically Based Pharmacokinetic (PBPK) Modeling and Simulation During Regulatory Review

    Clinical Pharmacology & Therapeutics

    Volume 89, Issue 2, February 2011, Pages: 259–267, P Zhao, L Zhang, JA Grillo, Q Liu, JM Bullock, YJ Moon, P Song, SS Brar, R Madabushi, TC Wu, BP Booth, NA Rahman, KS Reynolds, E Gil Berglund, LJ Lesko and S-M Huang

    Version of Record online : 29 DEC 2010, DOI: 10.1038/clpt.2010.298

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    PHRMA CPCDC initiative on predictive models of human pharmacokinetics, part 5: Prediction of plasma concentration–time profiles in human by using the physiologically-based pharmacokinetic modeling approach

    Journal of Pharmaceutical Sciences

    Volume 100, Issue 10, October 2011, Pages: 4127–4157, Patrick Poulin, Rhys D. O. Jones, Hannah M. Jones, Christopher R. Gibson, Malcolm Rowland, Jenny Y. Chien, Barbara J. Ring, Kimberly K. Adkison, M. Sherry Ku, Handan He, Ragini Vuppugalla, Punit Marathe, Volker Fischer, Sandeep Dutta, Vikash K. Sinha, Thorir Björnsson, Thierry Lavé and James W. T. Yates

    Version of Record online : 3 MAY 2011, DOI: 10.1002/jps.22550

  13. Physiologically Based Pharmacokinetic (PBPK) Modeling in Children

    Clinical Pharmacology & Therapeutics

    Volume 92, Issue 1, July 2012, Pages: 40–49, J S Barrett, O Della Casa Alberighi, S Läer and B Meibohm

    Version of Record online : 6 JUN 2012, DOI: 10.1038/clpt.2012.64

  14. Prediction of pharmacokinetics prior to In Vivo studies. II. Generic physiologically based pharmacokinetic models of drug disposition

    Journal of Pharmaceutical Sciences

    Volume 91, Issue 5, May 2002, Pages: 1358–1370, Patrick Poulin and Frank-Peter Theil

    Version of Record online : 28 MAR 2002, DOI: 10.1002/jps.10128

  15. Physiologically based pharmacokinetic models of small molecules and therapeutic antibodies: a mini-review on fundamental concepts and applications

    Biopharmaceutics & Drug Disposition

    Volume 37, Issue 2, March 2016, Pages: 75–92, Gregory Z. Ferl, Frank-Peter Theil and Harvey Wong

    Version of Record online : 30 MAR 2016, DOI: 10.1002/bdd.1994

  16. Physiologically Based Pharmacokinetic and Pharmacodynamic Modeling

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    Mouse Models of Human Cancer

    Raymond S. H. Yang, James E. Dennison, Melvin E. Andersen, Ying C. Ou, Kai H. Liao and Brad Reisfeld

    Published Online : 15 OCT 2004, DOI: 10.1002/0471675067.mmc023

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    Physiologically based pharmacokinetic (PBPK) modelling tools: how to fit with our needs?

    Biopharmaceutics & Drug Disposition

    Volume 33, Issue 2, March 2012, Pages: 55–71, François Bouzom, Kathryn Ball, Nathalie Perdaems and Bernard Walther

    Version of Record online : 26 JAN 2012, DOI: 10.1002/bdd.1767

  18. You have full text access to this OnlineOpen article
    Physiologically Based Pharmacokinetic Modeling and Simulation in Pediatric Drug Development

    CPT: Pharmacometrics & Systems Pharmacology

    Volume 3, Issue 11, November 2014, Pages: 1–13, A R Maharaj and A N Edginton

    Version of Record online : 19 NOV 2014, DOI: 10.1038/psp.2014.45

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    Applied Concepts in PBPK Modeling: How to Build a PBPK/PD Model

    CPT: Pharmacometrics & Systems Pharmacology

    Volume 5, Issue 10, October 2016, Pages: 516–531, L Kuepfer, C Niederalt, T Wendl, J-F Schlender, S Willmann, J Lippert, M Block, T Eissing and D Teutonico

    Version of Record online : 19 OCT 2016, DOI: 10.1002/psp4.12134

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    Optimizing pharmacokinetic bridging studies in paediatric oncology using physiologically-based pharmacokinetic modelling: application to docetaxel

    British Journal of Clinical Pharmacology

    Volume 80, Issue 3, September 2015, Pages: 534–547, Hoai-Thu Thai, Florent Mazuir, Sylvaine Cartot-Cotton and Christine Veyrat-Follet

    Version of Record online : 14 AUG 2015, DOI: 10.1111/bcp.12702