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There are 38923 results for: content related to: Degenerating Regenerating Torsades de Pointes

  1. Detection of TDP-43 oligomers in frontotemporal lobar degeneration–TDP

    Annals of Neurology

    Volume 78, Issue 2, August 2015, Pages: 211–221, Patricia F. Kao, Yun-Ru Chen, Xiao-Bo Liu, Charles DeCarli, William W. Seeley and Lee-Way Jin

    Version of Record online : 30 JUN 2015, DOI: 10.1002/ana.24431

  2. Phosphorylated and cleaved TDP-43 in ALS, FTLD and other neurodegenerative disorders and in cellular models of TDP-43 proteinopathy

    Neuropathology

    Volume 30, Issue 2, April 2010, Pages: 170–181, Tetsuaki Arai, Masato Hasegawa, Takashi Nonoka, Fuyuki Kametani, Makiko Yamashita, Masato Hosokawa, Kazuhiro Niizato, Kuniaki Tsuchiya, Zen Kobayashi, Kenji Ikeda, Mari Yoshida, Mitsumoto Onaya, Hiroshige Fujishiro and Haruhiko Akiyama

    Version of Record online : 19 JAN 2010, DOI: 10.1111/j.1440-1789.2009.01089.x

  3. Review: Transactive response DNA-binding protein 43 (TDP-43): mechanisms of neurodegeneration

    Neuropathology and Applied Neurobiology

    Volume 36, Issue 2, April 2010, Pages: 97–112, T. F. Gendron, K. A. Josephs and L. Petrucelli

    Version of Record online : 23 MAR 2010, DOI: 10.1111/j.1365-2990.2010.01060.x

  4. TDP-43 loss of function increases TFEB activity and blocks autophagosome–lysosome fusion

    The EMBO Journal

    Volume 35, Issue 2, 18 January 2016, Pages: 121–142, Qin Xia, Hongfeng Wang, Zongbing Hao, Cheng Fu, Qingsong Hu, Feng Gao, Haigang Ren, Dong Chen, Junhai Han, Zheng Ying and Guanghui Wang

    Version of Record online : 23 DEC 2015, DOI: 10.15252/embj.201591998

  5. You have full text access to this OnlineOpen article
    Review: Prion-like mechanisms of transactive response DNA binding protein of 43 kDa (TDP-43) in amyotrophic lateral sclerosis (ALS)

    Neuropathology and Applied Neurobiology

    Volume 41, Issue 5, August 2015, Pages: 578–597, Phillip Smethurst, Katie Claire Louise Sidle and John Hardy

    Version of Record online : 20 APR 2015, DOI: 10.1111/nan.12206

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    Significance and limitation of the pathological classification of TDP-43 proteinopathy

    Neuropathology

    Volume 34, Issue 6, December 2014, Pages: 578–588, Tetsuaki Arai

    Version of Record online : 8 SEP 2014, DOI: 10.1111/neup.12138

  7. TAR DNA-binding protein 43 and pathological subtype of Alzheimer's disease impact clinical features

    Annals of Neurology

    Volume 78, Issue 5, November 2015, Pages: 697–709, Keith A. Josephs, Jennifer L. Whitwell, Nirubol Tosakulwong, Stephen D. Weigand, Melissa E. Murray, Amanda M. Liesinger, Leonard Petrucelli, Matthew L. Senjem, Robert J. Ivnik, Joseph E. Parisi, Ronald C. Petersen and Dennis W. Dickson

    Version of Record online : 16 SEP 2015, DOI: 10.1002/ana.24493

  8. You have full text access to this OnlineOpen article
    Spliceosome integrity is defective in the motor neuron diseases ALS and SMA

    EMBO Molecular Medicine

    Volume 5, Issue 2, February 2013, Pages: 221–234, Hitomi Tsuiji, Yohei Iguchi, Asako Furuya, Ayane Kataoka, Hiroyuki Hatsuta, Naoki Atsuta, Fumiaki Tanaka, Yoshio Hashizume, Hiroyasu Akatsu, Shigeo Murayama, Gen Sobue and Koji Yamanaka

    Version of Record online : 25 JAN 2013, DOI: 10.1002/emmm.201202303

  9. Ubiquitinated, p62 immunopositive cerebellar cortical neuronal inclusions are evident across the spectrum of TDP-43 proteinopathies but are only rarely additionally immunopositive for phosphorylation-dependent TDP-43

    Neuropathology

    Volume 31, Issue 3, June 2011, Pages: 239–249, Andrew King, Satomi Maekawa, Istvan Bodi, Claire Troakes and Safa Al-Sarraj

    Version of Record online : 1 DEC 2010, DOI: 10.1111/j.1440-1789.2010.01171.x

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    TDP-43: the relationship between protein aggregation and neurodegeneration in amyotrophic lateral sclerosis and frontotemporal lobar degeneration

    The FEBS Journal

    Volume 278, Issue 19, October 2011, Pages: 3539–3549, Robert H. Baloh

    Version of Record online : 24 AUG 2011, DOI: 10.1111/j.1742-4658.2011.08256.x

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    What is the key player in TDP-43 pathology in ALS: Disappearance from the nucleus or inclusion formation in the cytoplasm?

    Neurology and Clinical Neuroscience

    Volume 1, Issue 1, January 2013, Pages: 11–17, Osamu Onodera, Akihiro Sugai, Takuya Konno, Mari Tada, Akihide Koyama and Masatoyo Nishizawa

    Version of Record online : 31 JAN 2013, DOI: 10.1002/ncn3.9

  12. p62/sequestosome 1 binds to TDP-43 in brains with frontotemporal lobar degeneration with TDP-43 inclusions

    Journal of Neuroscience Research

    Volume 90, Issue 10, October 2012, Pages: 2034–2042, Kunikazu Tanji, Hai-Xin Zhang, Fumiaki Mori, Akiyoshi Kakita, Hitoshi Takahashi and Koichi Wakabayashi

    Version of Record online : 5 JUN 2012, DOI: 10.1002/jnr.23081

  13. TDP-35 sequesters TDP-43 into cytoplasmic inclusions through binding with RNA

    FEBS Letters

    Volume 589, Issue 15, July 08, 2015, Pages: 1920–1928, Mei-Xia Che, Lei-Lei Jiang, Hai-Yin Li, Ya-Jun Jiang and Hong-Yu Hu

    Version of Record online : 19 JUN 2015, DOI: 10.1016/j.febslet.2015.06.009

  14. RNA-binding proteins in neurodegenerative disease: TDP-43 and beyond

    Wiley Interdisciplinary Reviews: RNA

    Volume 3, Issue 2, March/April 2012, Pages: 265–285, Keith A. Hanson, Sang Hwa Kim and Randal S. Tibbetts

    Version of Record online : 25 OCT 2011, DOI: 10.1002/wrna.111

  15. Genetic strategies to study TDP-43 in rodents and to develop preclinical therapeutics for amyotrophic lateral sclerosis

    European Journal of Neuroscience

    Volume 34, Issue 8, October 2011, Pages: 1179–1188, David B. Wang, Michael A. Gitcho, Brian C. Kraemer and Ronald L. Klein

    Version of Record online : 21 JUL 2011, DOI: 10.1111/j.1460-9568.2011.07803.x

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    Biomarkers and endogenous determinants of dofetilide-induced torsades de pointes in α1-adrenoceptor-stimulated, anaesthetized rabbits

    British Journal of Pharmacology

    Volume 161, Issue 7, December 2010, Pages: 1477–1495, Attila S. Farkas, László Rudas, Péter Makra, Norbert Csík, István Leprán, Tamás Forster, Miklós Csanády, Julius Gy. Papp, András Varró and András Farkas

    Version of Record online : 5 NOV 2010, DOI: 10.1111/j.1476-5381.2010.00965.x

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    TDP-43 and FUS/TLS: cellular functions and implications for neurodegeneration

    The FEBS Journal

    Volume 278, Issue 19, October 2011, Pages: 3550–3568, Fabienne C. Fiesel and Philipp J. Kahle

    Version of Record online : 24 AUG 2011, DOI: 10.1111/j.1742-4658.2011.08258.x

  18. Cytoplasmic TDP-43 accumulation in cells of the adrenal medulla in individuals with or without amyotrophic lateral sclerosis

    Neuropathology

    Volume 34, Issue 6, December 2014, Pages: 535–540, Koichi Okamoto, Masakuni Amari, Yukio Fujita, Kouki Makioka, Toshio Fukuda, Keiji Suzuki and Masamitsu Takatama

    Version of Record online : 11 JUL 2014, DOI: 10.1111/neup.12139

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    Adenoviral expression of TDP-43 and FUS genes and shRNAs for protein degradation pathways in rodent motoneurons in vitro and in vivo

    Neuropathology

    Volume 34, Issue 1, February 2014, Pages: 83–98, Kazuhiko Watabe, Keiko Akiyama, Emiko Kawakami, Tomohiro Ishii, Kentaro Endo, Hiroko Yanagisawa, Kazunori Sango and Masami Tsukamoto

    Version of Record online : 12 AUG 2013, DOI: 10.1111/neup.12058

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    Knockdown of transactive response DNA-binding protein (TDP-43) downregulates histone deacetylase 6

    The EMBO Journal

    Volume 29, Issue 1, January 6, 2010, Pages: 209–221, Fabienne C Fiesel, Aaron Voigt, Stephanie S Weber, Chris Van den Haute, Andrea Waldenmaier, Karin Görner, Michael Walter, Marlene L Anderson, Jeannine V Kern, Tobias M Rasse, Thorsten Schmidt, Wolfdieter Springer, Roland Kirchner, Michael Bonin, Manuela Neumann, Veerle Baekelandt, Marianna Alunni-Fabbroni, Jörg B Schulz and Philipp J Kahle

    Version of Record online : 12 NOV 2009, DOI: 10.1038/emboj.2009.324