Search Results

There are 105577 results for: content related to: A Novel Missense Mutation Causing a G487R Substitution in the S2–S3 Loop of Human ether-à-go-go -Related Gene Channel

  1. You have full text access to this OnlineOpen article
    Modification by KCNE1 variants of the hERG potassium channel response to premature stimulation and to pharmacological inhibition

    Physiological Reports

    Volume 1, Issue 6, November 2013, Chunyun Du, Aziza El Harchi, Henggui Zhang and Jules C. Hancox

    Version of Record online : 29 NOV 2013, DOI: 10.1002/phy2.175

  2. You have free access to this content
    Modulation of hERG potassium currents in HEK-293 cells by protein kinase C. Evidence for direct phosphorylation of pore forming subunits

    The Journal of Physiology

    Volume 581, Issue 2, June 2007, Pages: 479–493, S. L. Cockerill, A. B. Tobin, I. Torrecilla, G. B. Willars, N. B. Standen and J. S. Mitcheson

    Version of Record online : 23 MAY 2007, DOI: 10.1113/jphysiol.2006.123414

  3. You have free access to this content
    N-linked glycosylation sites determine HERG channel surface membrane expression

    The Journal of Physiology

    Volume 515, Issue 1, February 1999, Pages: 41–48, Kevin Petrecca, Roxana Atanasiu, Armin Akhavan and Alvin Shrier

    Version of Record online : 8 SEP 2004, DOI: 10.1111/j.1469-7793.1999.041ad.x

  4. The EGFP/hERG fusion protein alter the electrophysiological properties of hERG channels in HEK293 cells

    Cell Biology International

    Volume 35, Issue 3, March 2011, Pages: 193–199, Na Huang, Jiang-Fang Lian, Jian-Hua Huo, Li-Ying Liu, Lei Ni, Xi Yang, Jian-Qing Zhou, Zong-Fang Li, Tu-Sheng Song and Chen Huang

    Version of Record online : 2 JAN 2013, DOI: 10.1042/CBI20100022

  5. Pharmacological rescue of hERG currents carried out by G604S and wide type hERG co-expression

    Clinical and Experimental Pharmacology and Physiology

    Volume 43, Issue 9, September 2016, Pages: 851–861, Jianhua Huo, Aifeng Zhang, Xueyan Guo, Hua Qiang, Ping Liu, Ling Bai and Aiqun Ma

    Version of Record online : 26 JUL 2016, DOI: 10.1111/1440-1681.12593

  6. You have free access to this content
    A comparison of currents carried by HERG, with and without coexpression of MiRP1, and the native rapid delayed rectifier current. Is MiRP1 the missing link?

    The Journal of Physiology

    Volume 540, Issue 1, April 2002, Pages: 15–27, Manjula Weerapura, Stanley Nattel, Denis Chartier, Ricardo Caballero and Terence E. Hébert

    Version of Record online : 22 JUL 2004, DOI: 10.1113/jphysiol.2001.013296

  7. Partially Dominant Mutant Channel Defect Corresponding with Intermediate LQT2 Phenotype

    Pacing and Clinical Electrophysiology

    Volume 35, Issue 1, January 2012, Pages: 3–16, YAMINI KRISHNAN, RENJIAN ZHENG, CHRISTINE WALSH, YINGYING TANG and THOMAS V. McDONALD

    Version of Record online : 25 SEP 2011, DOI: 10.1111/j.1540-8159.2011.03222.x

  8. You have free access to this content
    Potential mechanisms for the enhancement of HERG K+ channel function by phospholipid metabolites

    British Journal of Pharmacology

    Volume 141, Issue 4, February 2004, Pages: 586–599, Jingxiong Wang, Yiqiang Zhang, Huizhen Wang, Hong Han, Stanley Nattel, Baofeng Yang and Zhiguo Wang

    Version of Record online : 30 JAN 2009, DOI: 10.1038/sj.bjp.0705646

  9. You have free access to this content
    Effect of S5P α-helix charge mutants on inactivation of hERG K+ channels

    The Journal of Physiology

    Volume 573, Issue 2, June 2006, Pages: 291–304, C. E. Clarke, A. P. Hill, J. Zhao, M. Kondo, R. N. Subbiah, T. J. Campbell and J. I. Vandenberg

    Version of Record online : 31 MAY 2006, DOI: 10.1113/jphysiol.2006.108332

  10. You have free access to this content
    Mutant MiRP1 subunits modulate HERG K+ channel gating: a mechanism for pro-arrhythmia in long QT syndrome type 6

    The Journal of Physiology

    Volume 551, Issue 1, August 2003, Pages: 253–262, Yu Lu, Martyn P. Mahaut-Smith, Christopher L.-H. Huang and Jamie I. Vandenberg

    Version of Record online : 16 JUL 2004, DOI: 10.1111/j.1469-7793.2003.00253.x

  11. Prediction of hERG Liability – Using SVM Classification, Bootstrapping and Jackknifing

    Molecular Informatics

    Hongmao Sun, Ruili Huang, Menghang Xia, Sampada Shahane, Noel Southall and Yuhong Wang

    Version of Record online : 21 DEC 2016, DOI: 10.1002/minf.201600126

  12. You have free access to this content
    Drug-induced long QT syndrome: hERG K+ channel block and disruption of protein trafficking by fluoxetine and norfluoxetine

    British Journal of Pharmacology

    Volume 149, Issue 5, November 2006, Pages: 481–489, S Rajamani, L L Eckhardt, C R Valdivia, C A Klemens, B M Gillman, C L Anderson, K M Holzem, B P Delisle, B D Anson, J C Makielski and C T January

    Version of Record online : 29 JAN 2009, DOI: 10.1038/sj.bjp.0706892

  13. Modeling hERG and its Interactions with Drugs: Recent Advances in Light of Current Potassium Channel Simulations

    ChemMedChem

    Volume 3, Issue 4, April 14, 2008, Pages: 523–535, Maurizio Recanatini, Andrea Cavalli and Matteo Masetti

    Version of Record online : 25 JAN 2008, DOI: 10.1002/cmdc.200700264

  14. Predicting Drug-Induced QT Prolongation and Torsades de Pointes: A Review of Preclinical Endpoint Measures

    Unit

    Current Protocols in Pharmacology

    10:10.16.1–10.16.19

    Claire Townsend and Barry S. Brown

    Published Online : 1 JUN 2013, DOI: 10.1002/0471141755.ph1016s61

  15. You have free access to this content
    14-3-3 amplifies and prolongs adrenergic stimulation of HERG K+ channel activity

    The EMBO Journal

    Volume 21, Issue 8, April 15, 2002, Pages: 1889–1898, Anna Kagan, Yonathan F. Melman, Andrew Krumerman and Thomas V. McDonald

    Version of Record online : 15 APR 2002, DOI: 10.1093/emboj/21.8.1889

  16. You have full text access to this OnlineOpen article
    Inhibition of hERG potassium channel by the antiarrhythmic agent mexiletine and its metabolite m-hydroxymexiletine

    Pharmacology Research & Perspectives

    Volume 3, Issue 5, October 2015, Roberta Gualdani, Francesco Tadini-Buoninsegni, Mariagrazia Roselli, Ivana Defrenza, Marialessandra Contino, Nicola Antonio Colabufo and Giovanni Lentini

    Version of Record online : 31 JUL 2015, DOI: 10.1002/prp2.160

  17. You have free access to this content
    The Effects of a Novel Anti-arrhythmic Drug, Acehytisine Hydrochloride, on the Human Ether-a-go-go Related Gene K+ Channel and Its Trafficking

    Basic & Clinical Pharmacology & Toxicology

    Volume 104, Issue 2, February 2009, Pages: 145–154, Xingfu Huang, Yanmin Yang, Jun Zhu, Yan Dai and Jielin Pu

    Version of Record online : 6 JAN 2009, DOI: 10.1111/j.1742-7843.2008.00357.x

  18. You have free access to this content
    Comparison of HERG channel blocking effects of various β-blockers – implication for clinical strategy

    British Journal of Pharmacology

    Volume 147, Issue 6, March 2006, Pages: 642–652, Kazunobu Kawakami, Toshihisa Nagatomo, Haruhiko Abe, Kan Kikuchi, Hiroko Takemasa, Blake D Anson, Brian P Delisle, Craig T January and Yasuhide Nakashima

    Version of Record online : 30 JAN 2009, DOI: 10.1038/sj.bjp.0706508

  19. You have free access to this content
    A mutation in the pore region of HERG K+ channels expressed in Xenopus oocytes reduces rectification by shifting the voltage dependence of inactivation

    The Journal of Physiology

    Volume 509, Issue 1, May 1998, Pages: 129–137, Anruo Zou, Qing P. Xu and Michael C. Sanguinetti

    Version of Record online : 22 SEP 2004, DOI: 10.1111/j.1469-7793.1998.129bo.x

  20. You have free access to this content
    Acute effects of oestrogen on the guinea pig and human IKr channels and drug-induced prolongation of cardiac repolarization

    The Journal of Physiology

    Volume 586, Issue 12, June 2008, Pages: 2961–2973, Junko Kurokawa, Masaji Tamagawa, Nobuhiro Harada, Shin-ichiro Honda, Chang-Xi Bai, Haruaki Nakaya and Tetsushi Furukawa

    Version of Record online : 28 JUN 2008, DOI: 10.1113/jphysiol.2007.150367