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There are 18067 results for: content related to: Pharmacotherapeutic targets in Alzheimer's disease

  1. β-Amyloid Therapeutic Strategies for Alzheimer's Disease

    Standard Article

    Burger's Medicinal Chemistry and Drug Discovery

    Bruno P. Imbimbo and Francesca Speroni

    Published Online : 14 OCT 2005, DOI: 10.1002/0471266949.bmc112

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    Antibody-based approaches in Alzheimer’s research: safety, pharmacokinetics, metabolism, and analytical tools

    Journal of Neurochemistry

    Volume 104, Issue 4, February 2008, Pages: 859–874, Peter Lichtlen and M. Hasan Mohajeri

    Version of Record online : 18 AUG 2008, DOI: 10.1111/j.1471-4159.2007.05064.x

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    Biomarkers for early diagnosis of Alzheimer disease: ‘ALZheimer ASsociated gene’– a new blood biomarker?

    Journal of Cellular and Molecular Medicine

    Volume 12, Issue 4, August 2008, Pages: 1094–1117, Kurt A. Jellinger, Bernd Janetzky, Johannes Attems and Elisabeth Kienzl

    Version of Record online : 19 MAR 2008, DOI: 10.1111/j.1582-4934.2008.00313.x

  4. The use of mass spectrometry to study amyloid-β peptides

    Mass Spectrometry Reviews

    Volume 30, Issue 3, May/June 2011, Pages: 347–365, Giuseppe Grasso

    Version of Record online : 22 NOV 2010, DOI: 10.1002/mas.20281

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    The turn formation at positions 22 and 23 in the 42-mer amyloid β peptide: The emerging role in the pathogenesis of Alzheimer's disease

    Geriatrics & Gerontology International

    Volume 10, Issue s1, July 2010, Pages: S169–S179, Kazuma Murakami, Yuichi Masuda, Takuji Shirasawa, Takahiko Shimizu and Kazuhiro Irie

    Version of Record online : 2 JUN 2010, DOI: 10.1111/j.1447-0594.2010.00598.x

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    Structural evolution and membrane interactions of Alzheimer's amyloid-beta peptide oligomers: New knowledge from single-molecule fluorescence studies

    Protein Science

    Volume 23, Issue 7, July 2014, Pages: 869–883, Robin D. Johnson, Duncan G. Steel and Ari Gafni

    Version of Record online : 4 JUN 2014, DOI: 10.1002/pro.2479

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    Low-n oligomers as therapeutic targets of Alzheimer’s disease

    Journal of Neurochemistry

    Volume 117, Issue 1, April 2011, Pages: 19–28, Kenjiro Ono and Masahito Yamada

    Version of Record online : 9 FEB 2011, DOI: 10.1111/j.1471-4159.2011.07187.x

  8. Oligomeric Aβ in Alzheimer's Disease: Relationship to Plaque and Tangle Pathology, APOE Genotype and Cerebral Amyloid Angiopathy

    Brain Pathology

    Volume 20, Issue 2, March 2010, Pages: 468–480, Zoë Van Helmond, James S. Miners, Patrick G. Kehoe and Seth Love

    Version of Record online : 16 JUL 2009, DOI: 10.1111/j.1750-3639.2009.00321.x

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    Are amyloid-degrading enzymes viable therapeutic targets in Alzheimer’s disease?

    Journal of Neurochemistry

    Volume 120, Issue s1, January 2012, Pages: 167–185, Natalia N. Nalivaeva, Caroline Beckett, Nikolai D. Belyaev and Anthony J. Turner

    Version of Record online : 28 NOV 2011, DOI: 10.1111/j.1471-4159.2011.07510.x

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    Restored degradation of the Alzheimer’s amyloid-β peptide by targeting amyloid formation

    Journal of Neurochemistry

    Volume 108, Issue 5, March 2009, Pages: 1198–1207, Peter J. Crouch, Deborah J. Tew, Tai Du, Diem Ngoc Nguyen, Aphrodite Caragounis, Gulay Filiz, Rachel E. Blake, Ian A. Trounce, Cynthia P. W. Soon, Katrina Laughton, Keyla A. Perez, Qiao-Xin Li, Robert A. Cherny, Colin L. Masters, Kevin J. Barnham and Anthony R. White

    Version of Record online : 7 JAN 2009, DOI: 10.1111/j.1471-4159.2009.05870.x

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    Pathogenic mechanisms of prion protein, amyloid-β and α-synuclein misfolding: the prion concept and neurotoxicity of protein oligomers

    Journal of Neurochemistry

    Volume 139, Issue 2, October 2016, Pages: 162–180, Cathryn L. Ugalde, David I. Finkelstein, Victoria A. Lawson and Andrew F. Hill

    Version of Record online : 15 SEP 2016, DOI: 10.1111/jnc.13772

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    Gene therapy in Alzheimer’s disease – potential for disease modification

    Journal of Cellular and Molecular Medicine

    Volume 14, Issue 4, April 2010, Pages: 741–757, Per Nilsson, Nobuhisa Iwata, Shin-ichi Muramatsu, Lars O. Tjernberg, Bengt Winblad and Takaomi C. Saido

    Version of Record online : 16 FEB 2010, DOI: 10.1111/j.1582-4934.2010.01038.x

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    CD4 T cells in immunity and immunotherapy of Alzheimer's disease


    Volume 139, Issue 4, August 2013, Pages: 438–446, Alon Monsonego, Anna Nemirovsky and Idan Harpaz

    Version of Record online : 2 JUL 2013, DOI: 10.1111/imm.12103

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    Toxicity mediated by soluble oligomers of β-amyloid(1–42) on cholinergic SN56.B5.G4 cells

    Journal of Neurochemistry

    Volume 98, Issue 6, September 2006, Pages: 1930–1945, Katrin Heinitz, Martin Beck, Reinhard Schliebs and J. Regino Perez-Polo

    Version of Record online : 10 JUL 2006, DOI: 10.1111/j.1471-4159.2006.04015.x

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    A novel tricyclic pyrone compound ameliorates cell death associated with intracellular amyloid-β oligomeric complexes

    Journal of Neurochemistry

    Volume 98, Issue 1, July 2006, Pages: 57–67, Izumi Maezawa, Hyun-Seok Hong, Hui-Chuan Wu, Srinivas K. Battina, Sandeep Rana, Takeo Iwamoto, Gary A. Radke, Erik Pettersson, George M. Martin, Duy H. Hua and Lee-Way Jin

    Version of Record online : 12 MAY 2006, DOI: 10.1111/j.1471-4159.2006.03862.x

  16. Apolipoprotein E receptor pathways in Alzheimer disease

    Wiley Interdisciplinary Reviews: Systems Biology and Medicine

    Volume 6, Issue 3, May/June 2014, Pages: 255–270, Vanessa Schmidt, Anne-Sophie Carlo and Thomas E. Willnow

    Version of Record online : 6 MAR 2014, DOI: 10.1002/wsbm.1262

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    β-Amyloid protein oligomers induced by metal ions and acid pH are distinct from those generated by slow spontaneous ageing at neutral pH

    European Journal of Biochemistry

    Volume 270, Issue 21, November 2003, Pages: 4282–4293, Genevieve M. J. A. Klug, Dusan Losic, Supundi, S. Subasinghe, Marie-Isabel Aguilar, Lisandra L. Martin and David H. Small

    Version of Record online : 6 OCT 2003, DOI: 10.1046/j.1432-1033.2003.03815.x

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    Membrane-targeted strategies for modulating APP and Aβ-mediated toxicity

    Journal of Cellular and Molecular Medicine

    Volume 13, Issue 2, February 2009, Pages: 249–261, Katherine A. Price, Peter J. Crouch, Paul S. Donnelly, Colin L. Masters, Anthony R. White and Cyril C. Curtain

    Version of Record online : 29 DEC 2008, DOI: 10.1111/j.1582-4934.2008.00642.x

  19. Oligomeropathies and pathogenesis of Alzheimer and Parkinson's diseases

    Movement Disorders

    Volume 31, Issue 6, June 2016, Pages: 771–781, Gianluigi Forloni, Vladimiro Artuso, Pietro La Vitola and Claudia Balducci

    Version of Record online : 31 MAR 2016, DOI: 10.1002/mds.26624

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    Low-density lipoprotein receptor-related protein-1: a serial clearance homeostatic mechanism controlling Alzheimer’s amyloid β-peptide elimination from the brain

    Journal of Neurochemistry

    Volume 115, Issue 5, December 2010, Pages: 1077–1089, Berislav V. Zlokovic, Rashid Deane, Abhay P. Sagare, Robert D. Bell and Ethan A. Winkler

    Version of Record online : 5 OCT 2010, DOI: 10.1111/j.1471-4159.2010.07002.x