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There are 12878 results for: content related to: Development of HIF-1 inhibitors for cancer therapy

  1. You have free access to this content
    NS398 reduces hypoxia-inducible factor (HIF)-1α and HIF-1 activity: Multiple-level effects involving cyclooxygenase-2 dependent and independent mechanisms

    International Journal of Cancer

    Volume 112, Issue 4, 20 November 2004, Pages: 585–595, Hua Zhong, Margaret Willard and Jonathan Simons

    Version of Record online : 30 JUN 2004, DOI: 10.1002/ijc.20438

  2. You have free access to this content
    Normoxic Expression of Hypoxia-Inducible Factor 1 in Rat Leydig Cells In Vivo and In Vitro

    Journal of Andrology

    Volume 32, Issue 3, May-June 2011, Pages: 307–323, Dr M. A. Palladino, P. R. Pirlamarla, J. McNamara, C. M. Sottas, N. Korah, M. P. Hardy, D. B. Hales and L. Hermo

    Version of Record online : 2 JAN 2013, DOI: 10.2164/jandrol.110.011494

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    HIF-1α and HIF-2α degradation is differentially regulated in nucleus pulposus cells of the intervertebral disc

    Journal of Bone and Mineral Research

    Volume 27, Issue 2, February 2012, Pages: 401–412, Nobuyuki Fujita, Kazuhiro Chiba, Irving M Shapiro and Makarand V Risbud

    Version of Record online : 23 JAN 2012, DOI: 10.1002/jbmr.538

  4. Oxygen homeostasis

    Wiley Interdisciplinary Reviews: Systems Biology and Medicine

    Volume 2, Issue 3, May/June 2010, Pages: 336–361, Gregg L. Semenza

    Version of Record online : 2 NOV 2009, DOI: 10.1002/wsbm.69

  5. Hypoxia-inducible factors – regulation, role and comparative aspects in tumourigenesis

    Veterinary and Comparative Oncology

    Volume 9, Issue 1, March 2011, Pages: 16–37, A. E. Hansen, A. T. Kristensen, I. Law, J. T. Jørgensen and S. A. Engelholm

    Version of Record online : 16 AUG 2010, DOI: 10.1111/j.1476-5829.2010.00233.x

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    Identification of Cys255 in HIF-1α as a novel site for development of covalent inhibitors of HIF-1α/ARNT PasB domain protein–protein interaction

    Protein Science

    Volume 21, Issue 12, December 2012, Pages: 1885–1896, Rosa Cardoso, Robert Love, Carol L. Nilsson, Simon Bergqvist, Dawn Nowlin, Jiangli Yan, Kevin K.-C. Liu, Jing Zhu, Ping Chen, Ya-Li Deng, H. Jane Dyson, Michael J. Greig and Alexei Brooun

    Version of Record online : 9 NOV 2012, DOI: 10.1002/pro.2172

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    Hypoxia-inducible factor-3α promotes angiogenic activity of pulmonary endothelial cells by repressing the expression of the VE-cadherin gene

    Genes to Cells

    Volume 20, Issue 3, March 2015, Pages: 224–241, Satomi Kobayashi, Toshiharu Yamashita, Kinuko Ohneda, Masumi Nagano, Kenichi Kimura, Hideto Nakai, Lorenz Poellinger and Osamu Ohneda

    Version of Record online : 28 JAN 2015, DOI: 10.1111/gtc.12215

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    HIF-1α and HIF-2α have divergent roles in colon cancer

    International Journal of Cancer

    Volume 124, Issue 4, 15 February 2009, Pages: 763–771, Takaaki Imamura, Hirotoshi Kikuchi, Maria-Teresa Herraiz, Do-Youn Park, Yusuke Mizukami, Mari Mino-Kenduson, Maureen P. Lynch, Bo R. Rueda, Yair Benita, Ramnik J. Xavier and Daniel C. Chung

    Version of Record online : 30 SEP 2008, DOI: 10.1002/ijc.24032

  9. Inhibition of HIF-1 alpha and VEGF expression by the chemopreventive bioflavonoid apigenin is accompanied by Akt inhibition in human prostate carcinoma PC3-M cells

    Molecular Carcinogenesis

    Volume 47, Issue 9, September 2008, Pages: 686–700, Salida Mirzoeva, Nam Deuk Kim, Karen Chiu, Carrie A. Franzen, Raymond C. Bergan and Jill C. Pelling

    Version of Record online : 31 JAN 2008, DOI: 10.1002/mc.20421

  10. Increase in gene dosage is a mechanism of HIF-1α constitutive expression in head and neck squamous cell carcinomas

    Genes, Chromosomes and Cancer

    Volume 48, Issue 5, May 2009, Pages: 441–454, Pablo Secades, Juan Pablo Rodrigo, Mario Hermsen, Cesar Alvarez, Carlos Suarez and María-Dolores Chiara

    Version of Record online : 23 FEB 2009, DOI: 10.1002/gcc.20652

  11. Prostaglandin F2α induces the normoxic activation of the hypoxia-inducible factor-1 transcription factor in differentiating 3T3-L1 preadipocytes: Potential role in the regulation of adipogenesis

    Journal of Cellular Biochemistry

    Volume 105, Issue 1, 1 September 2008, Pages: 89–98, Li Liu and Neil A. Clipstone

    Version of Record online : 6 MAY 2008, DOI: 10.1002/jcb.21801

  12. Hypoxia-inducible factor-dependent production of profibrotic mediators by hypoxic hepatocytes

    Liver International

    Volume 29, Issue 7, August 2009, Pages: 1010–1021, Bryan L. Copple, Juan J. Bustamante, Timothy P. Welch, Nam Deuk Kim and Jeon-Ok Moon

    Version of Record online : 19 MAR 2009, DOI: 10.1111/j.1478-3231.2009.02015.x

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    Mechanism of regulation of the hypoxia-inducible factor-1α by the von Hippel-Lindau tumor suppressor protein

    The EMBO Journal

    Volume 19, Issue 16, August 15, 2000, Pages: 4298–4309, Keiji Tanimoto, Yuichi Makino, Teresa Pereira and Lorenz Poellinger

    Version of Record online : 15 AUG 2000, DOI: 10.1093/emboj/19.16.4298

  14. Retinal neuroprotection by hypoxic preconditioning is independent of hypoxia-inducible factor-1α expression in photoreceptors

    European Journal of Neuroscience

    Volume 29, Issue 12, June 2009, Pages: 2291–2302, Markus Thiersch, Christina Lange, Sandrine Joly, Severin Heynen, Yun Zheng Le, Marijana Samardzija and Christian Grimm

    Version of Record online : 8 JUN 2009, DOI: 10.1111/j.1460-9568.2009.06781.x

  15. Recent agents targeting HIF-1α for cancer therapy

    Journal of Cellular Biochemistry

    Volume 114, Issue 3, March 2013, Pages: 498–509, Yaozhong Hu, Jing Liu and He Huang

    Version of Record online : 22 JAN 2013, DOI: 10.1002/jcb.24390

  16. TNFα induces expression of HIF-1α mRNA and protein but inhibits hypoxic stimulation of HIF-1 transcriptional activity in airway smooth muscle cells

    Journal of Cellular Physiology

    Volume 228, Issue 8, August 2013, Pages: 1745–1753, Stamatina Tsapournioti, Ilias Mylonis, Apostolia Hatziefthimiou, Maria G. Ioannou, Rodopi Stamatiou, Georgios K. Koukoulis, George Simos, Paschalis-Adam Molyvdas and Efrosyni Paraskeva

    Version of Record online : 18 APR 2013, DOI: 10.1002/jcp.24331

  17. Functional regulation of HIF-1α under normoxia—is there more than post-translational regulation?

    Journal of Cellular Physiology

    Volume 227, Issue 2, February 2012, Pages: 514–524, A. Kuschel, P. Simon and S. Tug

    Version of Record online : 23 NOV 2011, DOI: 10.1002/jcp.22798

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    2-Methoxyestradiol confers neuroprotection and inhibits a maladaptive HIF-1α response after traumatic brain injury in mice

    Journal of Neurochemistry

    Volume 129, Issue 6, June 2014, Pages: 940–954, Eva-Verena Schaible, Julia Windschügl, Wiesia Bobkiewicz, Yordan Kaburov, Larissa Dangel, Tobias Krämer, Changsheng Huang, Anne Sebastiani, Clara Luh, Christian Werner, Kristin Engelhard, Serge C. Thal and Michael K.E. Schäfer

    Version of Record online : 2 APR 2014, DOI: 10.1111/jnc.12708

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    HIF-1α and HIF-2α play a central role in stretch-induced but not shear-stress-induced angiogenesis in rat skeletal muscle

    The Journal of Physiology

    Volume 583, Issue 2, September 2007, Pages: 753–766, Malgorzata Milkiewicz, Jennifer L. Doyle, Tomasz Fudalewski, Eric Ispanovic, Maliheh Aghasi and Tara L. Haas

    Version of Record online : 30 AUG 2007, DOI: 10.1113/jphysiol.2007.136325

  20. You have free access to this content
    Expression of hypoxia-inducible factor 1α in brain tumors


    Volume 88, Issue 11, 1 June 2000, Pages: 2606–2618, David Zagzag, Hua Zhong, Joanne M. Scalzitti, Erik Laughner, Jonathan W. Simons and Gregg L. Semenza

    Version of Record online : 20 NOV 2000, DOI: 10.1002/1097-0142(20000601)88:11<2606::AID-CNCR25>3.0.CO;2-W