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There are 12810 results for: content related to: Two sides to every story: the HIF-dependent and HIF-independent functions of pVHL

  1. You have full text access to this OnlineOpen article
    Combined mutation of Vhl and Trp53 causes renal cysts and tumours in mice

    EMBO Molecular Medicine

    Volume 5, Issue 6, June 2013, Pages: 949–964, Joachim Albers, Michal Rajski, Désirée Schönenberger, Sabine Harlander, Peter Schraml, Adriana von Teichman, Strahil Georgiev, Peter J. Wild, Holger Moch, Wilhelm Krek and Ian J. Frew

    Version of Record online : 22 APR 2013, DOI: 10.1002/emmm.201202231

  2. Simulation of the mutation F76del on the von Hippel–Lindau tumor suppressor protein: Mechanism of the disease and implications for drug development

    Proteins: Structure, Function, and Bioinformatics

    Volume 81, Issue 2, February 2013, Pages: 349–363, Gabriel Limaverde-Sousa, Ester de Andrade Barreto, Carlos Gil Ferreira and José Cláudio Casali-da-Rocha

    Version of Record online : 26 OCT 2012, DOI: 10.1002/prot.24191

  3. Regulation of E2F1 by the von Hippel–Lindau tumour suppressor protein predicts survival in renal cell cancer patients

    The Journal of Pathology

    Volume 231, Issue 1, September 2013, Pages: 117–129, Dorus A Mans, Joost S Vermaat, Bart G Weijts, Ellen van Rooijen, Jeroen van Reeuwijk, Karsten Boldt, Laura GM Daenen, Petra van der Groep, Benjamin D Rowland, Judith J Jans, Ronald Roepman, Emile E Voest, Paul J van Diest, Marianne C Verhaar, Alain de Bruin and Rachel H Giles

    Version of Record online : 6 AUG 2013, DOI: 10.1002/path.4219

  4. You have free access to this content
    The VHL protein recruits a novel KRAB-A domain protein to repress HIF-1α transcriptional activity

    The EMBO Journal

    Volume 22, Issue 8, April 15, 2003, Pages: 1857–1867, Zaibo Li, Dakun Wang, Xi Na, Susan R. Schoen, Edward M. Messing and Guan Wu

    Version of Record online : 15 APR 2003, DOI: 10.1093/emboj/cdg173

  5. You have free access to this content
    The multifaceted von Hippel–Lindau tumour suppressor protein

    FEBS Letters

    Volume 588, Issue 16, August 19, 2014, Pages: 2704–2711, Claire M. Robinson and Michael Ohh

    Version of Record online : 25 FEB 2014, DOI: 10.1016/j.febslet.2014.02.026

  6. You have free access to this content
    Identification of the RNA polymerase II subunit hsRPB7 as a novel target of the von Hippel—Lindau protein

    The EMBO Journal

    Volume 22, Issue 16, August 15, 2003, Pages: 4249–4259, Xi Na, Hai Ou Duan, Edward M. Messing, Susan R. Schoen, Charlotte K. Ryan, P.Anthony di Sant'Agnese, Erica A. Golemis and Guan Wu

    Version of Record online : 15 AUG 2003, DOI: 10.1093/emboj/cdg410

  7. You have free access to this content
    pVHL and PTEN tumour suppressor proteins cooperatively suppress kidney cyst formation

    The EMBO Journal

    Volume 27, Issue 12, June 18, 2008, Pages: 1747–1757, Ian J Frew, Claudio R Thoma, Strahil Georgiev, Andrea Minola, Manuela Hitz, Matteo Montani, Holger Moch and Wilhelm Krek

    Version of Record online : 22 MAY 2008, DOI: 10.1038/emboj.2008.96

  8. You have free access to this content
    Failure to prolyl hydroxylate hypoxia-inducible factor α phenocopies VHL inactivation in vivo

    The EMBO Journal

    Volume 25, Issue 19, October 4, 2006, Pages: 4650–4662, William Y Kim, Michal Safran, Marshall RM Buckley, Benjamin L Ebert, Jonathan Glickman, Marcus Bosenberg, Meredith Regan and William G Kaelin Jr

    Version of Record online : 14 SEP 2006, DOI: 10.1038/sj.emboj.7601300

  9. You have free access to this content
    Von Hippel-Lindau gene alterations in sporadic benign and malignant pheochromocytomas

    International Journal of Cancer

    Volume 105, Issue 2, 10 June 2003, Pages: 190–195, Hilde Dannenberg, Ronald R. De Krijger, Erwin van der Harst, Mustaffa Abbou, Ynske IJzendoorn, Paul Komminoth and Winand N.M. Dinjens

    Version of Record online : 5 MAR 2003, DOI: 10.1002/ijc.11060

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    The von Hippel–Lindau tumour suppressor interacts with microtubules through kinesin-2

    FEBS Letters

    Volume 581, Issue 24, October 02, 2007, Pages: 4571–4576, Martijn P. Lolkema, Dorus A. Mans, Cristel M. Snijckers, Mascha van Noort, Moniek van Beest, Emile E. Voest and Rachel H. Giles

    Version of Record online : 31 AUG 2007, DOI: 10.1016/j.febslet.2007.08.050

  11. You have free access to this content
    Identification and In Silico Analysis of Novel von Hippel-Lindau (VHL) Gene Variants from a Large Population

    Annals of Human Genetics

    Volume 75, Issue 4, July 2011, Pages: 483–496, Emanuela Leonardi, Maddalena Martella, Silvio C.E. Tosatto and Alessandra Murgia

    Version of Record online : 4 APR 2011, DOI: 10.1111/j.1469-1809.2011.00647.x

  12. You have free access to this content
    Treatment of kidney cancer

    Cancer

    Volume 115, Issue S10, 15 May 2009, Pages: 2262–2272, William G. Kaelin Jr

    Version of Record online : 28 APR 2009, DOI: 10.1002/cncr.24232

  13. Effects of point mutations in pVHL on the binding of HIF-1α

    Proteins: Structure, Function, and Bioinformatics

    Volume 80, Issue 3, March 2012, Pages: 733–746, Carmen Domene and Christopher J. R. Illingworth

    Version of Record online : 22 NOV 2011, DOI: 10.1002/prot.23230

  14. You have free access to this content
    Vascular endothelial growth factor overexpression is correlated with von Hippel-Lindau tumor suppressor gene inactivation in patients with sporadic renal cell carcinoma

    Cancer

    Volume 95, Issue 1, 1 July 2002, Pages: 47–53, Hiroshi Igarashi, Mariko Esumi, Hajime Ishida and Kiyoki Okada

    Version of Record online : 28 JUN 2002, DOI: 10.1002/cncr.10635

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    Adding structural information to the von Hippel–Lindau (VHL) tumor suppressor interaction network

    FEBS Letters

    Volume 583, Issue 22, November 19, 2009, Pages: 3704–3710, E. Leonardi, A. Murgia and S.C.E. Tosatto

    Version of Record online : 28 OCT 2009, DOI: 10.1016/j.febslet.2009.10.070

  16. You have free access to this content
    von Hippel-Lindau tumor suppressor protein stimulation by thrombin involves RhoA activation

    International Journal of Cancer

    Volume 112, Issue 5, 10 December 2004, Pages: 777–786, Sandra Turcotte, Richard R. Desrosiers, Geneviève Brand and Richard Béliveau

    Version of Record online : 15 JUL 2004, DOI: 10.1002/ijc.20468

  17. You have full text access to this OnlineOpen article
    Clinical and functional properties of novel VHL mutation (X214L) consistent with Type 2A phenotype and low risk of renal cell carcinoma

    Clinical Genetics

    Volume 79, Issue 6, June 2011, Pages: 539–545, AD Sorrell, S Lee, C Stolle, J Ellenhorn, A Grix, WG Kaelin Jr and JN Weitzel

    Version of Record online : 13 MAY 2010, DOI: 10.1111/j.1399-0004.2010.01464.x

  18. The von Hippel–Lindau (VHL) germline mutation V84L manifests as early-onset bilateral pheochromocytoma

    American Journal of Medical Genetics Part A

    Volume 140A, Issue 7, 1 April 2006, Pages: 685–690, Mary-Alice Abbott, Katherine L. Nathanson, Simon Nightingale, Eamonn R. Maher and Robert M. Greenstein

    Version of Record online : 24 FEB 2006, DOI: 10.1002/ajmg.a.31116

  19. pVHL co-ordinately regulates CXCR4/CXCL12 and MMP2/MMP9 expression in human clear-cell renal cell carcinoma

    The Journal of Pathology

    Volume 214, Issue 4, March 2008, Pages: 464–471, K Struckmann, KD Mertz, S Steu, M Storz, P Staller, W Krek, P Schraml and H Moch

    Version of Record online : 11 DEC 2007, DOI: 10.1002/path.2310

  20. Comprehensive mutational analysis of the VHL gene in sporadic renal cell carcinoma: Relationship to clinicopathological parameters

    Genes, Chromosomes and Cancer

    Volume 34, Issue 1, May 2002, Pages: 58–68, Keiichi Kondo, Masahiro Yao, Minoru Yoshida, Takeshi Kishida, Taro Shuin, Takeshi Miura, Masatoshi Moriyama, Kazuki Kobayashi, Naoki Sakai, Shigeki Kaneko, Satoshi Kawakami, Masaya Baba, Noboru Nakaigawa, Yoji Nagashima, Yukio Nakatani and Masahiko Hosaka

    Version of Record online : 7 FEB 2002, DOI: 10.1002/gcc.10054