Search Results

There are 16075 results for: content related to: Central and peripheral components of exercise-related fatigability in myotonic dystrophy type 1

  1. Investigating the Nonclinical ADME and PK/PD of an Antibody–Drug Conjugate: A Case Study of Ado-Trastuzumab Emtansine (T-DM1)

    Standard Article

    Pharmaceutical Sciences Encyclopedia

    Jay Tibbitts

    Published Online : 30 DEC 2015, DOI: 10.1002/9780470571224.pse561

  2. Effects of Trastuzumab Emtansine (T-DM1) on QT Interval and Safety of Pertuzumab Plus T-DM1 in Patients With Previously Treated Human Epidermal Growth Factor Receptor 2–Positive Metastatic Breast Cancer

    Clinical Pharmacology in Drug Development

    Volume 2, Issue 1, January 2013, Pages: 11–24, Manish Gupta, Bei Wang, Timothy J. Carrothers, Patricia M. LoRusso, Yu-Waye Chu, Ted Shih, David Loecke, Amita Joshi, Ola Saad, Joo-Hee Yi and Sandhya Girish

    Version of Record online : 26 FEB 2013, DOI: 10.1002/cpdd.9

  3. Clinical Implications of Pathophysiological and Demographic Covariates on the Population Pharmacokinetics of Trastuzumab Emtansine, a HER2-Targeted Antibody-Drug Conjugate, in Patients With HER2-Positive Metastatic Breast Cancer

    The Journal of Clinical Pharmacology

    Volume 52, Issue 5, May 2012, Pages: 691–703, Dr Manish Gupta, Dr Patricia M. LoRusso, Ms Bei Wang, Ms Joo-Hee Yi, Dr Howard A. Burris III, Dr Muralidhar Beeram, Dr Shanu Modi, Dr Yu-Waye Chu, Dr Samuel Agresta, Dr Barbara Klencke, Dr Amita Joshi and Dr Sandhya Girish

    Version of Record online : 7 MAR 2013, DOI: 10.1177/0091270011403742

  4. You have free access to this content
    A phase 1 study of weekly dosing of trastuzumab emtansine (T-DM1) in patients with advanced human epidermal growth factor 2–positive breast cancer

    Cancer

    Volume 118, Issue 23, 1 December 2012, Pages: 5733–5740, Muralidhar Beeram, Ian E. Krop, Howard A. Burris, Sandhya R. Girish, Wei Yu, Michael W. Lu, Scott N. Holden and Shanu Modi

    Version of Record online : 30 MAY 2012, DOI: 10.1002/cncr.27622

  5. You have free access to this content
    Developmental insights into the pathology of and therapeutic strategies for DM1: Back to the basics

    Developmental Dynamics

    Volume 244, Issue 3, March 2015, Pages: 377–390, Anthony Chau and Auinash Kalsotra

    Version of Record online : 13 JAN 2015, DOI: 10.1002/dvdy.24240

  6. DS-8201a, a new HER2-targeting antibody–drug conjugate incorporating a novel DNA topoisomerase I inhibitor, overcomes HER2-positive gastric cancer T-DM1 resistance

    International Journal of Cancer

    Volume 141, Issue 8, 15 October 2017, Pages: 1682–1689, Naoki Takegawa, Yoshikane Nonagase, Kimio Yonesaka, Kazuko Sakai, Osamu Maenishi, Yusuke Ogitani, Takao Tamura, Kazuto Nishio, Kazuhiko Nakagawa and Junji Tsurutani

    Version of Record online : 12 JUL 2017, DOI: 10.1002/ijc.30870

  7. Observation and modelling of main-sequence star chromospheres – XV. New constraints on the dynamo mechanisms for dM1 stars

    Monthly Notices of the Royal Astronomical Society

    Volume 411, Issue 4, March 2011, Pages: 2259–2276, E. R. Houdebine

    Version of Record online : 14 JAN 2011, DOI: 10.1111/j.1365-2966.2010.17846.x

  8. Population pharmacokinetics and exposure–response of trastuzumab emtansine in advanced breast cancer previously treated with ≥2 HER2-targeted regimens

    British Journal of Clinical Pharmacology

    Volume 83, Issue 12, December 2017, Pages: 2767–2777, Shang-Chiung Chen, Angelica Quartino, Daniel Polhamus, Matthew Riggs, Jonathan French, Xin Wang, Shweta Vadhavkar, Melanie Smitt, Silke Hoersch, Alexander Strasak, Jin Yan Jin, Sandhya Girish and Chunze Li

    Version of Record online : 3 SEP 2017, DOI: 10.1111/bcp.13381

  9. Semi-mechanistic Population Pharmacokinetic Model of Multivalent Trastuzumab Emtansine in Patients with Metastatic Breast Cancer

    Clinical Pharmacology & Therapeutics

    Volume 92, Issue 4, October 2012, Pages: 520–527, V L Chudasama, F Schaedeli Stark, J M Harrold, J Tibbitts, S R Girish, M Gupta, N Frey and D E Mager

    Version of Record online : 12 SEP 2012, DOI: 10.1038/clpt.2012.153

  10. A Smart Nano-Prodrug Platform with Reactive Drug Loading, Superb Stability, and Fast Responsive Drug Release for Targeted Cancer Therapy

    Macromolecular Bioscience

    Volume 17, Issue 10, October 2017, Hao Meng, Yan Zou, Ping Zhong, Fenghua Meng, Jian Zhang, Ru Cheng and Zhiyuan Zhong

    Version of Record online : 2 MAY 2017, DOI: 10.1002/mabi.201600518

  11. Risk of skin cancer among patients with myotonic dystrophy type 1 based on primary care physician data from the U.K. Clinical Practice Research Datalink

    International Journal of Cancer

    Youjin Wang, Ruth M. Pfeiffer, Rotana Alsaggaf, Wilhelmine Meeraus, Julia C. Gage, Lesley A. Anderson, Renée C. Bremer, Nikoletta Nikolenko, Hanns Lochmuller, Mark H. Greene and Shahinaz M. Gadalla

    Version of Record online : 20 NOV 2017, DOI: 10.1002/ijc.31143

  12. Prevalence of allergic symptoms among children with diabetes mellitus type 1 of different socioeconomic status

    Pediatric Diabetes

    Volume 9, Issue 4pt2, August 2008, Pages: 407–416, Kyriaki Karavanaki, Eleni Tsoka, Christina Karayianni, Vassilis Petrou, Eleni Pippidou, Maria Brisimitzi, Maria Mavrikiou, Kostas Kakleas, Ilias Konstantopoulos, Manolis Manoussakis and Catherine Dacou-Voutetakis

    Version of Record online : 29 JUL 2008, DOI: 10.1111/j.1399-5448.2008.00444.x

  13. Impact of clinical status and salivary conditions on xerostomia and oral health-related quality of life of adolescents with type 1 diabetes mellitus

    Community Dentistry and Oral Epidemiology

    Volume 40, Issue 1, February 2012, Pages: 62–69, Ivana Maria Saes Busato, Sérgio Aparecido Ignácio, João Armando Brancher, Simone Tetu Moysés and Luciana Reis Azevedo-Alanis

    Version of Record online : 25 AUG 2011, DOI: 10.1111/j.1600-0528.2011.00635.x

  14. Psychological characteristics of patients with myotonic dystrophy type 1

    Acta Neurologica Scandinavica

    Volume 132, Issue 1, July 2015, Pages: 49–58, J. A. Bertrand, S. Jean, L. Laberge, C. Gagnon, J. Mathieu, J. F. Gagnon and L. Richer

    Version of Record online : 11 DEC 2014, DOI: 10.1111/ane.12356

  15. You have full text access to this OnlineOpen article
    Aberrant intracellular metabolism of T-DM1 confers T-DM1 resistance in human epidermal growth factor receptor 2-positive gastric cancer cells

    Cancer Science

    Volume 108, Issue 7, July 2017, Pages: 1458–1468, Hongbin Wang, Wenqian Wang, Yongping Xu, Yong Yang, Xiaoyan Chen, Haitian Quan and Liguang Lou

    Version of Record online : 23 MAY 2017, DOI: 10.1111/cas.13253

  16. Observation and modelling of main-sequence star chromospheres – XVIII. Observations of the Ca ii resonance lines and Hα line for dM4 stars and dK5 stars

    Monthly Notices of the Royal Astronomical Society

    Volume 421, Issue 4, April 2012, Pages: 3189–3205, E. R. Houdebine

    Version of Record online : 13 MAR 2012, DOI: 10.1111/j.1365-2966.2012.20649.x

  17. You have free access to this content
    Interaction of musleblind, CUG-BP1 and hnRNP H proteins in DM1-associated aberrant IR splicing

    The EMBO Journal

    Volume 25, Issue 18, September 20, 2006, Pages: 4271–4283, Sharan Paul, Warunee Dansithong, Dongho Kim, John Rossi, Nicholas JG Webster, Lucio Comai and Sita Reddy

    Version of Record online : 31 AUG 2006, DOI: 10.1038/sj.emboj.7601296

  18. Alternative splicing alterations of Ca2+ handling genes are associated with Ca2+ signal dysregulation in myotonic dystrophy type 1 (DM1) and type 2 (DM2) myotubes

    Neuropathology and Applied Neurobiology

    Volume 40, Issue 4, June 2014, Pages: 464–476, Massimo Santoro, Roberto Piacentini, Marcella Masciullo, Maria Laura Ester Bianchi, Anna Modoni, Maria Vittoria Podda, Enzo Ricci, Gabriella Silvestri and Claudio Grassi

    Version of Record online : 22 APR 2014, DOI: 10.1111/nan.12076

  19. Myotonic dystrophy 1 in the nervous system: From the clinic to molecular mechanisms

    Journal of Neuroscience Research

    Volume 86, Issue 1, January 2008, Pages: 18–26, Mario Bermúdez de León and Bulmaro Cisneros

    Version of Record online : 4 JUN 2007, DOI: 10.1002/jnr.21377

  20. Cerebral involvement in myotonic dystrophies

    Muscle & Nerve

    Volume 36, Issue 3, September 2007, Pages: 294–306, Giovanni Meola and Valeria Sansone

    Version of Record online : 7 MAY 2007, DOI: 10.1002/mus.20800