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There are 30652 results for: content related to: Tolerability and safety of perampanel: two randomized dose-escalation studies

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    The clinical pharmacology profile of the new antiepileptic drug perampanel: A novel noncompetitive AMPA receptor antagonist

    Epilepsia

    Volume 56, Issue 1, January 2015, Pages: 12–27, Philip N. Patsalos

    Version of Record online : 13 DEC 2014, DOI: 10.1111/epi.12865

  2. You have full text access to this OnlineOpen article
    Psychiatric and behavioral adverse events in randomized clinical studies of the noncompetitive AMPA receptor antagonist perampanel

    Epilepsia

    Volume 56, Issue 8, August 2015, Pages: 1252–1263, Alan B. Ettinger, Antonia LoPresti, Haichen Yang, Betsy Williams, Sharon Zhou, Randi Fain and Antonio Laurenza

    Version of Record online : 3 JUL 2015, DOI: 10.1111/epi.13054

  3. You have full text access to this OnlineOpen article
    Perampanel for focal epilepsy: insights from early clinical experience

    Acta Neurologica Scandinavica

    Volume 133, Issue 3, March 2016, Pages: 160–172, E. Trinka, B. J. Steinhoff, M. Nikanorova and M. J. Brodie

    Version of Record online : 28 OCT 2015, DOI: 10.1111/ane.12529

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    Perampanel for adjunctive treatment of partial-onset seizures: A pooled dose–response analysis of phase III studies

    Epilepsia

    Volume 55, Issue 3, March 2014, Pages: 423–431, Lynn D. Kramer, Andrew Satlin, Gregory L. Krauss, Jacqueline French, Emilio Perucca, Elinor Ben-Menachem, Patrick Kwan, Jerry J. Shih, Antonio Laurenza, Haichen Yang, Jin Zhu and David Squillacote

    Version of Record online : 7 MAR 2014, DOI: 10.1111/epi.12527

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    Concentration–effect relationships with perampanel in patients with pharmacoresistant partial-onset seizures

    Epilepsia

    Volume 54, Issue 8, August 2013, Pages: 1490–1497, Barry E. Gidal, Jim Ferry, Oneeb Majid and Ziad Hussein

    Version of Record online : 17 JUN 2013, DOI: 10.1111/epi.12240

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    Perampanel Study 207: long-term open-label evaluation in patients with epilepsy

    Acta Neurologica Scandinavica

    Volume 126, Issue 4, October 2012, Pages: 263–269, I. Rektor, G. L. Krauss, M. Bar, V. Biton, J. A. Klapper, N. Vaiciene-Magistris, R. Kuba, D. Squillacote, M. Gee and D. Kumar

    Version of Record online : 23 AUG 2012, DOI: 10.1111/ane.12001

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    Perampanel, a selective, noncompetitive α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor antagonist, as adjunctive therapy for refractory partial-onset seizures: Interim results from phase III, extension study 307

    Epilepsia

    Volume 54, Issue 1, January 2013, Pages: 126–134, Gregory L. Krauss, Emilio Perucca, Elinor Ben-Menachem, Patrick Kwan, Jerry J. Shih, David Squillacote, Haichen Yang, Michelle Gee, Jin Zhu and Antonio Laurenza

    Version of Record online : 20 AUG 2012, DOI: 10.1111/j.1528-1167.2012.03648.x

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    Perampanel efficacy and safety by gender: Subanalysis of phase III randomized clinical studies in subjects with partial seizures

    Epilepsia

    Volume 56, Issue 7, July 2015, Pages: e90–e94, Blanca Vazquez, Haichen Yang, Betsy Williams, Sharon Zhou and Antonio Laurenza

    Version of Record online : 11 JUN 2015, DOI: 10.1111/epi.13019

  9. HPLC with fluorescence detection assay of perampanel, a novel AMPA receptor antagonist, in human plasma for clinical pharmacokinetic studies

    Biomedical Chromatography

    Volume 29, Issue 10, October 2015, Pages: 1589–1593, Yuji Mano, Osamu Takenaka and Kazutomi Kusano

    Version of Record online : 31 MAR 2015, DOI: 10.1002/bmc.3463

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    Safety and tolerability of perampanel: a review of clinical trial data

    Acta Neurologica Scandinavica

    Volume 127, Issue s197, April 2013, Pages: 30–35, J. M. Serratosa, V. Villanueva, F. Kerling and B. S. Kasper

    Version of Record online : 11 MAR 2013, DOI: 10.1111/ane.12102

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    Analysis of falls in patients with epilepsy enrolled in the perampanel phase III randomized double-blind studies

    Epilepsia

    Volume 58, Issue 1, January 2017, Pages: 51–59, Ilo E. Leppik, Haichen Yang, Betsy Williams, Sharon Zhou, Randi Fain, Anna Patten, Francesco Bibbiani and Antonio Laurenza

    Version of Record online : 21 NOV 2016, DOI: 10.1111/epi.13600

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    Perampanel: A novel, orally active, noncompetitive AMPA-receptor antagonist that reduces seizure activity in rodent models of epilepsy

    Epilepsia

    Volume 52, Issue 7, July 2011, Pages: 1331–1340, Takahisa Hanada, Yutaka Hashizume, Naoki Tokuhara, Osamu Takenaka, Naohiro Kohmura, Aichi Ogasawara, Shinji Hatakeyama, Makoto Ohgoh, Masataka Ueno and Yukio Nishizawa

    Version of Record online : 2 JUN 2011, DOI: 10.1111/j.1528-1167.2011.03109.x

  13. You have full text access to this OnlineOpen article
    Impact of perampanel on pharmacokinetics of concomitant antiepileptics in patients with partial-onset seizures: pooled analysis of clinical trials

    British Journal of Clinical Pharmacology

    Volume 82, Issue 2, August 2016, Pages: 422–430, Oneeb Majid, Antonio Laurenza, Jim Ferry and Ziad Hussein

    Version of Record online : 10 MAY 2016, DOI: 10.1111/bcp.12951

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    Review of clinical studies of perampanel in adolescent patients

    Brain and Behavior

    Volume 6, Issue 9, September 2016, Heung Dong Kim, Ching-Shiang Chi, Tayard Desudchit, Marina Nikanorova, Anannit Visudtibhan, Charcrin Nabangchang, Derrick W. S. Chan, Choong Yi Fong, Kai-Ping Chang, Shang-Yeong Kwan, Fe De Los Reyes, Chao-Ching Huang, Surachai Likasitwattanakul, Wang-Tso Lee, Ada Yung and Amitabh Dash

    Version of Record online : 28 JUN 2016, DOI: 10.1002/brb3.505

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    Efficacy and safety of adjunctive perampanel for the treatment of refractory partial seizures: A pooled analysis of three phase III studies

    Epilepsia

    Volume 54, Issue 8, August 2013, Pages: 1481–1489, Bernhard J. Steinhoff, Elinor Ben-Menachem, Philippe Ryvlin, Simon Shorvon, Lynn Kramer, Andrew Satlin, David Squillacote, Haichen Yang, Jin Zhu and Antonio Laurenza

    Version of Record online : 10 MAY 2013, DOI: 10.1111/epi.12212

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    Adjunctive perampanel in adolescents with inadequately controlled partial-onset seizures: A randomized study evaluating behavior, efficacy, and safety

    Epilepsia

    Volume 57, Issue 7, July 2016, Pages: 1120–1129, Lieven Lagae, Vicente Villanueva, Kimford J. Meador, Makarand Bagul, Antonio Laurenza, Dinesh Kumar and Haichen Yang

    Version of Record online : 25 MAY 2016, DOI: 10.1111/epi.13417

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    Preclinical pharmacology of perampanel, a selective non-competitive AMPA receptor antagonist

    Acta Neurologica Scandinavica

    Volume 127, Issue s197, April 2013, Pages: 19–24, M. A. Rogawski and T. Hanada

    Version of Record online : 11 MAR 2013, DOI: 10.1111/ane.12100

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    Synergism of perampanel and zonisamide in the rat amygdala kindling model of temporal lobe epilepsy

    Epilepsia

    Volume 57, Issue 4, April 2016, Pages: 638–647, Vera Russmann, Josephine D. Salvamoser, Maruja L. Rettenbeck, Takafumi Komori and Heidrun Potschka

    Version of Record online : 8 FEB 2016, DOI: 10.1111/epi.13328

  19. Behavioural changes in patients with intellectual disability treated with perampanel

    Acta Neurologica Scandinavica

    E. Andres, F. Kerling, H. Hamer, B. Kasper and M. Winterholler

    Version of Record online : 1 JUN 2017, DOI: 10.1111/ane.12781

  20. You have full text access to this OnlineOpen article
    Long-term safety of perampanel and seizure outcomes in refractory partial-onset seizures and secondarily generalized seizures: Results from phase III extension study 307

    Epilepsia

    Volume 55, Issue 7, July 2014, Pages: 1058–1068, Gregory L. Krauss, Emilio Perucca, Elinor Ben-Menachem, Patrick Kwan, Jerry J. Shih, Jean-François Clément, Xuefeng Wang, Makarand Bagul, Michelle Gee, Jin Zhu and David Squillacote

    Version of Record online : 27 MAY 2014, DOI: 10.1111/epi.12643