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There are 4458 results for: content related to: IgG-Fc-mediated effector functions: molecular definition of interaction sites for effector ligands and the role of glycosylation

  1. The generation of a humanized, non-mitogenic CD3 monoclonal antibody which retains in vitro immunosuppressive properties

    European Journal of Immunology

    Volume 23, Issue 2, February 1993, Pages: 403–411, Sarah Bolt, Edward Routledge, Irene Lloyd, Lucienne Chatenoud, Heather Pope, Scott D. Gorman, Mike Clark and Herman Waldmann

    Article first published online : 7 DEC 2005, DOI: 10.1002/eji.1830230216

  2. Quality attributes of recombinant therapeutic proteins: An assessment of impact on safety and efficacy as part of a quality by design development approach

    Biotechnology Progress

    Volume 28, Issue 3, May/June 2012, Pages: 608–622, Alex Eon-Duval, Hervé Broly and Ralf Gleixner

    Article first published online : 2 MAY 2012, DOI: 10.1002/btpr.1548

  3. Avidity confers FcγR binding and immune effector function to aglycosylated immunoglobulin G1

    Journal of Molecular Recognition

    Volume 25, Issue 3, March 2012, Pages: 147–154, Thomas C. Nesspor, T. Shantha Raju, Chen -Ni Chin, Omid Vafa and Randall J. Brezski

    Article first published online : 28 FEB 2012, DOI: 10.1002/jmr.2155

  4. Efficient expression and purification of human aglycosylated Fcγ receptors in Escherichia coli

    Biotechnology and Bioengineering

    Volume 107, Issue 1, 1 September 2010, Pages: 21–30, Sang Taek Jung, Tae Hyun Kang and George Georgiou

    Article first published online : 7 MAY 2010, DOI: 10.1002/bit.22785

  5. Salt-induced aggregation of a monoclonal human immunoglobulin G1

    Journal of Pharmaceutical Sciences

    Volume 102, Issue 2, February 2013, Pages: 377–386, Jonathan Rubin, Lars Linden, Wayne M. Coco, Andreas S. Bommarius and Sven H. Behrens

    Article first published online : 12 NOV 2012, DOI: 10.1002/jps.23363

  6. Glycosylation influences on the aggregation propensity of therapeutic monoclonal antibodies

    Biotechnology Journal

    Volume 6, Issue 1, January 2011, Pages: 38–44, Veysel Kayser, Naresh Chennamsetty, Vladimir Voynov, Kurt Forrer, Bernhard Helk and Professor Bernhardt L. Trout

    Article first published online : 14 OCT 2010, DOI: 10.1002/biot.201000091

  7. Genetically-Engineered Antibodies: Tools for the Study of Diverse Properties of the Antibody Molecule

    Immunological Reviews

    Volume 130, Issue 1, December 1992, Pages: 87–107, Setjng-Uon Shin, Ann Wright, Vincent Bonagura and Sherie L. Morrison

    Article first published online : 28 APR 2006, DOI: 10.1111/j.1600-065X.1992.tb01522.x

  8. You have full text access to this OnlineOpen article
    Expression and characterization of truncated forms of humanized L243 IgG1

    European Journal of Biochemistry

    Volume 267, Issue 24, December 2000, Pages: 7246–7257, John Lund, Noriko Takahashi, Andrew Popplewell, Margaret Goodall, John D. Pound, Ruth Tyler, David J. King and Royston Jefferis

    Article first published online : 25 DEC 2001, DOI: 10.1046/j.1432-1327.2000.01839.x

  9. The glycosylation of red cell autoantibodies affects their functional activity in vitro

    British Journal of Haematology

    Volume 91, Issue 3, November 1995, Pages: 587–594, Andrew G. Hadley, Barbara Zupanska, Belinda M. Kumpel, Clarissa Pilkington, Helen L. Griffiths, Katherine A. Leader, Jeff Jones, David J. Booker, Robert Stamps and Robert J. Sokol

    Article first published online : 12 MAR 2008, DOI: 10.1111/j.1365-2141.1995.tb05352.x

  10. Comparative in vitro and experimental in vivo studies of the anti–epidermal growth factor receptor antibody nimotuzumab and its aglycosylated form produced in transgenic tobacco plants

    Plant Biotechnology Journal

    Volume 11, Issue 1, January 2013, Pages: 53–65, Meilyn Rodríguez, Lincidio Pérez, Jorge V. Gavilondo, Greta Garrido, Mónica Bequet-Romero, Ignacio Hernández, Vivian Huerta, Gleysin Cabrera, Marlene Pérez, Osmani Ramos, René Leyva, Mariela León, Pedro Luis Ramos, Ada Triguero, Abel Hernández, Belinda Sánchez, Marta Ayala, Jeny Soto, Ernesto González, Osmani Mendoza, Kenia Tiel and Merardo Pujol

    Article first published online : 10 OCT 2012, DOI: 10.1111/pbi.12006

  11. You have full text access to this OnlineOpen article
    Potential for recombinant immunoglobulin constructs in the management of carcinoma


    Volume 73, Issue S3, 1 February 1994, Pages: 1105–1113, Patricia Horan Hand, S. V. S. Kashmiri and Jeffrey Schlom

    Article first published online : 28 JUN 2006, DOI: 10.1002/1097-0142(19940201)73:3+<1105::AID-CNCR2820731351>3.0.CO;2-M

  12. You have free access to this content
    L1-CAM-targeted antibody therapy and 177Lu-radioimmunotherapy of disseminated ovarian cancer

    International Journal of Cancer

    Volume 130, Issue 11, 1 June 2012, Pages: 2715–2721, Eliane Fischer, Jürgen Grünberg, Susan Cohrs, Alexander Hohn, Karin Waldner-Knogler, Simone Jeger, Kurt Zimmermann, Ilse Novak-Hofer and Roger Schibli

    Article first published online : 29 AUG 2011, DOI: 10.1002/ijc.26321

  13. You have free access to this content
    Glycosylation of Recombinant Antibody Therapeutics

    Biotechnology Progress

    Volume 21, Issue 1, 2005, Pages: 11–16, Royston Jefferis

    Article first published online : 5 SEP 2008, DOI: 10.1021/bp040016j

  14. Antibody Glycosylation

    Post-translational Modification of Protein Biopharmaceuticals

    Gary Walsh, Pages: 79–108, 2009

    Published Online : 25 SEP 2009, DOI: 10.1002/9783527626601.ch4

  15. You have full text access to this OnlineOpen article
    Secretory expression of glycosylated and aglycosylated mutein of onconase from Pichia pastoris using different secretion signals and their purification and characterization

    FEMS Yeast Research

    Volume 9, Issue 4, June 2009, Pages: 591–599, Hong Liang Zhao, Qing He, Chong Xue, Bo Sun, Xue Qin Yao and Zhi Min Liu

    Article first published online : 16 MAR 2009, DOI: 10.1111/j.1567-1364.2009.00498.x

  16. Plant recombinant erythropoietin attenuates inflammatory kidney cell injury

    Plant Biotechnology Journal

    Volume 7, Issue 2, February 2009, Pages: 183–199, Andrew J. Conley, Kanishka Mohib, Anthony M. Jevnikar and Jim E. Brandle

    Article first published online : 28 NOV 2008, DOI: 10.1111/j.1467-7652.2008.00389.x

  17. Recombinant antibodies: Engineering and production in yeast and bacterial hosts

    Biotechnology Journal

    Volume 6, Issue 1, January 2011, Pages: 16–27, Professor Ki Jun Jeong, Seung Hoon Jang and Natarajan Velmurugan

    Article first published online : 17 DEC 2010, DOI: 10.1002/biot.201000381

  18. You have full text access to this OnlineOpen article
    Fc-Disabled Anti-Mouse CD40L Antibodies Retain Efficacy in Promoting Transplantation Tolerance

    American Journal of Transplantation

    Volume 8, Issue 11, November 2008, Pages: 2265–2271, S. R. Daley, S. P. Cobbold and H. Waldmann

    Article first published online : 8 SEP 2008, DOI: 10.1111/j.1600-6143.2008.02382.x

  19. Transient expression in tobacco leaves of an aglycosylated recombinant antibody against the epidermal growth factor receptor

    Biotechnology and Bioengineering

    Volume 89, Issue 2, 20 January 2005, Pages: 188–194, Meilyn Rodríguez, Nadia I. Ramírez, Marta Ayala, Freya Freyre, Lincidio Pérez, Ada Triguero, Cristina Mateo, Guillermo Selman-Housein, Jorge V. Gavilondo and Merardo Pujol

    Article first published online : 6 DEC 2004, DOI: 10.1002/bit.20333

  20. Immunoglobulin domains in Escherichia coli and other enterobacteria: from pathogenesis to applications in antibody technologies

    FEMS Microbiology Reviews

    Volume 37, Issue 2, March 2013, Pages: 204–250, Gustavo Bodelón, Carmen Palomino and Luis Ángel Fernández

    Article first published online : 23 JUL 2012, DOI: 10.1111/j.1574-6976.2012.00347.x