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There are 5676 results for: content related to: T-cell receptor proximal signaling via the Src-family kinases, Lck and Fyn, influences T-cell activation, differentiation, and tolerance

  1. You have free access to this content
    Lck plays a critical role in Ca2+ mobilization and CD28 costimulation in mature primary T cells

    European Journal of Immunology

    Volume 31, Issue 12, December 2001, Pages: 3567–3579, Patty A. Trobridge and Steven D. Levin

    Version of Record online : 19 NOV 2001, DOI: 10.1002/1521-4141(200112)31:12<3567::AID-IMMU3567>3.0.CO;2-M

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    S-acylation of LCK protein tyrosine kinase is essential for its signalling function in T lymphocytes

    The EMBO Journal

    Volume 16, Issue 16, August 15, 1997, Pages: 4983–4998, Panagiotis S. Kabouridis, Anthony I. Magee and Steven C. Ley

    Version of Record online : 15 AUG 1997, DOI: 10.1093/emboj/16.16.4983

  3. You have free access to this content
    HIV-1 Nef disrupts membrane-microdomain-associated anterograde transport for plasma membrane delivery of selected Src family kinases

    Cellular Microbiology

    Volume 15, Issue 10, October 2013, Pages: 1605–1621, Xiaoyu Pan, Miriam M. Geist, Jochen M. Rudolph, Walter Nickel and Oliver T. Fackler

    Version of Record online : 3 MAY 2013, DOI: 10.1111/cmi.12148

  4. You have free access to this content
    Signalling during hypoxia in human T lymphocytes – critical role of the src protein tyrosine kinase p56Lck in the O2 sensitivity of Kv1.3 channels

    The Journal of Physiology

    Volume 573, Issue 2, June 2006, Pages: 357–370, Peter Szigligeti, Lisa Neumeier, Eugene Duke, Claire Chougnet, Koichi Takimoto, Susan Molleran Lee, Alexandra H. Filipovich and Laura Conforti

    Version of Record online : 31 MAY 2006, DOI: 10.1113/jphysiol.2006.109967

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    HIV-1 infection is facilitated in T cells by decreasing p56lck protein tyrosine kinase activity

    Clinical & Experimental Immunology

    Volume 133, Issue 1, July 2003, Pages: 78–90, S. YOUSEFI, X.-Z. MA, R. SINGLA, Y.-C. ZHOU, D. SAKAC, M. BALI, Y. Liu, B. M. SAHAI and D. R. BRANCH

    Version of Record online : 24 JUN 2003, DOI: 10.1046/j.1365-2249.2003.02187.x

  6. The influence of the src-family kinases, Lck and Fyn, on T cell differentiation, survival and activation

    Immunological Reviews

    Volume 191, Issue 1, February 2003, Pages: 107–118, Rose Zamoyska, 1 Albert Basson, 2 Andrew Filby, 1 Giuseppe Legname, 3 Matthew Lovatt and 1 Benedict Seddon 1

    Version of Record online : 5 MAR 2003, DOI: 10.1034/j.1600-065X.2003.00015.x

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    The C terminus of T cell-specific adapter protein (TSAd) is necessary for TSAd-mediated inhibition of Lck activity

    European Journal of Immunology

    Volume 35, Issue 5, May 2005, Pages: 1612–1620, Vibeke Sundvold-Gjerstad, Stine Granum, Tomas Mustelin, Thorny C. B. Andersen, Tone Berge, Michael J. Shapiro, Virginia S. Shapiro, Anne Spurkland and Tor Lea

    Version of Record online : 13 APR 2005, DOI: 10.1002/eji.200425638

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    Increased ubiquitination and reduced expression of LCK in T lymphocytes from patients with systemic lupus erythematosus

    Arthritis & Rheumatism

    Volume 48, Issue 5, May 2003, Pages: 1343–1354, Elizabeth C. Jury, Panagiotis S. Kabouridis, Amina Abba, Rizgar A. Mageed and David A. Isenberg

    Version of Record online : 6 MAY 2003, DOI: 10.1002/art.10978

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    Targeting of CD45 protein tyrosine phosphatase activity to lipid microdomains on the T cell surface inhibits TCR signaling

    European Journal of Immunology

    Volume 32, Issue 9, September 2002, Pages: 2578–2587, Xiao He, Terry A. Woodford-Thomas, Kenneth G. Johnson, Dulari D. Shah and Matthew L. Thomas

    Version of Record online : 22 AUG 2002, DOI: 10.1002/1521-4141(200209)32:9<2578::AID-IMMU2578>3.0.CO;2-3

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    Altered dynamics in Lck SH3 upon binding to the LBD1 domain of Herpesvirus saimiri Tip

    Protein Science

    Volume 15, Issue 10, October 2006, Pages: 2402–2410, David D. Weis, Peter Kjellen, Bartholomew M. Sefton and John R. Engen

    Version of Record online : 1 JAN 2009, DOI: 10.1110/ps.052016406

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    Lck regulates IL-10 expression in memory-like Th1 cells

    European Journal of Immunology

    Volume 40, Issue 11, November 2010, Pages: 3210–3219, Kyeorda L. Kemp, Steven D. Levin and Paul L. Stein

    Version of Record online : 27 OCT 2010, DOI: 10.1002/eji.201040699

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    Single-cell analysis of siRNA-mediated gene silencing using multiparameter flow cytometry

    Cytometry Part A

    Volume 69A, Issue 2, February 2006, Pages: 59–65, Steven M. Chan, Janelle A. Olson and Paul J. Utz

    Version of Record online : 17 JAN 2006, DOI: 10.1002/cyto.a.20209

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    Cell transformation by Herpesvirus saimiri

    Journal of Cellular Physiology

    Volume 203, Issue 2, May 2005, Pages: 305–318, Alexander Y. Tsygankov

    Version of Record online : 23 SEP 2004, DOI: 10.1002/jcp.20225

  14. Mechanism of Lck Recruitment to the T-Cell Receptor Cluster as Studied by Single-Molecule-Fluorescence Video Imaging

    ChemPhysChem

    Volume 4, Issue 6, June 16, 2003, Pages: 620–626, Hiroshi Ike, Atsushi Kosugi, Akiko Kato, Ryota Iino, Hidemi Hirano, Takahiro Fujiwara, Ken Ritchie and Akihiro Kusumi

    Version of Record online : 6 JUN 2003, DOI: 10.1002/cphc.200300670

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    Lck protein tyrosine kinase is a key regulator of T-cell activation and a target for signal intervention by Herpesvirus saimiri and other viral gene products

    European Journal of Biochemistry

    Volume 267, Issue 12, June 2000, Pages: 3413–3421, Noah Isakov and Brigitte Biesinger

    Version of Record online : 18 AUG 2003, DOI: 10.1046/j.1432-1327.2000.01412.x

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    Ephrin-A1 stimulates migration of CD8+CCR7+ T lymphocytes

    European Journal of Immunology

    Volume 37, Issue 8, August 2007, Pages: 2326–2336, Hanne S. Hjorthaug and Hans-Christian Aasheim

    Version of Record online : 17 JUL 2007, DOI: 10.1002/eji.200737111

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    The heterotrimeric G-protein α-subunit Gαq regulates TCR-mediated immune responses through an Lck-dependent pathway

    European Journal of Immunology

    Volume 38, Issue 11, November 2008, Pages: 3208–3218, Jacob Ngai, Trond Methi, Kjetil Wessel Andressen, Finn Olav Levy, Knut Martin Torgersen, Torkel Vang, Nina Wettschureck and Kjetil Taskén

    Version of Record online : 7 NOV 2008, DOI: 10.1002/eji.200838195

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    Development of T-leukaemias in CD45 tyrosine phosphatase-deficient mutant lck mice

    The EMBO Journal

    Volume 19, Issue 17, September 1, 2000, Pages: 4644–4654, Matthew Baker, John Gamble, Reuben Tooze, Dominic Higgins, Feng Tang Yang, Patricia C.M. O'Brien, Nicholas Coleman, Sabine Pingel, Martin Turner and Denis R. Alexander

    Version of Record online : 1 SEP 2000, DOI: 10.1093/emboj/19.17.4644

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    Glucocorticoids cause rapid dissociation of a T-cell-receptor-associated protein complex containing LCK and FYN

    EMBO reports

    Volume 7, Issue 10, October 2006, Pages: 1023–1029, Mark Löwenberg, Auke P Verhaar, Joyce Bilderbeek, Jan van Marle, Frank Buttgereit, Maikel P Peppelenbosch, Sander J van Deventer and Daniel W Hommes

    Version of Record online : 4 AUG 2006, DOI: 10.1038/sj.embor.7400775

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    Transduction of naive CD4 T cells with kinase-deficient Lck-HIV-Tat fusion protein dampens T cell activation and provokes a switch to regulatory function

    European Journal of Immunology

    Volume 35, Issue 1, January 2005, Pages: 207–216, Marc Veldhoen, Anthony I. Magee, Mario N. Penha-Goncalves and Brigitta Stockinger

    Version of Record online : 3 DEC 2004, DOI: 10.1002/eji.200425542