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There are 32555 results for: content related to: Unravelling the twists and turns of the serpinopathies

  1. You have free access to this content
    A novel monoclonal antibody to characterize pathogenic polymers in liver disease associated with α1-antitrypsin deficiency

    Hepatology

    Volume 52, Issue 3, September 2010, Pages: 1078–1088, Elena Miranda, Juan Pérez, Ugo I. Ekeowa, Nedim Hadzic, Noor Kalsheker, Bibek Gooptu, Bernard Portmann, Didier Belorgey, Marian Hill, Susan Chambers, Jeff Teckman, Graeme J. Alexander, Stefan J. Marciniak and David A. Lomas

    Version of Record online : 14 MAY 2010, DOI: 10.1002/hep.23760

  2. You have full text access to this OnlineOpen article
    An integrative approach combining ion mobility mass spectrometry, X-ray crystallography, and nuclear magnetic resonance spectroscopy to study the conformational dynamics of α1-antitrypsin upon ligand binding

    Protein Science

    Volume 24, Issue 8, August 2015, Pages: 1301–1312, Mun Peak Nyon, Tanya Prentice, Jemma Day, John Kirkpatrick, Ganesh N. Sivalingam, Geraldine Levy, Imran Haq, James A. Irving, David A. Lomas, John Christodoulou, Bibek Gooptu and Konstantinos Thalassinos

    Version of Record online : 14 JUL 2015, DOI: 10.1002/pro.2706

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    Molecular pathogenesis of liver disease in α1-antitrypsin deficiency

    Hepatology

    Volume 24, Issue 6, December 1996, Pages: 1504–1516, J H Teckman, D Qu and D H Perlmutter

    Version of Record online : 30 DEC 2003, DOI: 10.1002/hep.510240635

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    Topography of a 2.0 Å structure of α1-antitrypsin reveals targets for rational drug design to prevent conformational disease

    Protein Science

    Volume 9, Issue 7, 2000, Pages: 1274–1281, Peter R. Elliott, Xue Y. Pei, Timothy R. Dafforn and David A. Lomas

    Version of Record online : 31 DEC 2008, DOI: 10.1110/ps.9.7.1274

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    Streptomyces erythraeus trypsin inactivates α1-antitrypsin

    FEBS Letters

    Volume 585, Issue 24, December 15, 2011, Pages: 3898–3902, Krishna M. Vukoti, Chandra Sekhar Rao Kadiyala and Masaru Miyagi

    Version of Record online : 21 NOV 2011, DOI: 10.1016/j.febslet.2011.11.015

  6. Familial conformational diseases and dementias

    Human Mutation

    Volume 20, Issue 1, July 2002, Pages: 1–14, Damian C. Crowther

    Version of Record online : 27 JUN 2002, DOI: 10.1002/humu.10100

  7. You have full text access to this OnlineOpen article
    Serpins show structural basis for oligomer toxicity and amyloid ubiquity

    FEBS Letters

    Volume 582, Issue 17, July 23, 2008, Pages: 2537–2541, Robin W. Carrell, Alec Mushunje and Aiwu Zhou

    Version of Record online : 23 JUN 2008, DOI: 10.1016/j.febslet.2008.06.021

  8. α1-antitrypsin prevents polymorphonuclear leucocyte-elastase effects on spermatozoa quality

    International Journal of Andrology

    Volume 33, Issue 1, February 2010, Pages: 64–72, J. Leßig, J. Arnhold and H.-J. Glander

    Version of Record online : 5 MAR 2009, DOI: 10.1111/j.1365-2605.2009.00954.x

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    Induction of α1-antitrypsin synthesis in human articular chondrocytes by interleukin-6–type cytokines: Evidence for a local acute-phase response in the joint

    Arthritis & Rheumatism

    Volume 42, Issue 9, September 1999, Pages: 1936–1945, Dagmar-Christiane Fischer, Barbara Siebertz, Eddy Van De Leur, Karl-Heinz Schiwy-Bochat, Lutz Graeve, Peter-C. Heinrich and Hans-Dieter Haubeck

    Version of Record online : 26 APR 2001, DOI: 10.1002/1529-0131(199909)42:9<1936::AID-ANR20>3.0.CO;2-K

  10. A novel binding site for the native hepatic acute-phase protein α1-antitrypsin expressed on the human hepatoma cell line HepG 2 and intestinal cell line Caco 2

    Liver

    Volume 20, Issue 3, June 2000, Pages: 240–246, Ivo Graziadei, Wolfgang Vogel and Adrian Bomford

    Version of Record online : 24 DEC 2001, DOI: 10.1034/j.1600-0676.2000.020003240.x

  11. Proteomic analysis revealed a strong association of a high level of α1-antitrypsin in gastric juice with gastric cancer

    PROTEOMICS

    Volume 4, Issue 11, No. 11 November 2004, Pages: 3343–3352, Kyunghee Lee, Minsu Kye, Joung Soon Jang, Ok Jae Lee, Taehyo Kim and Dongbin Lim

    Version of Record online : 20 SEP 2004, DOI: 10.1002/pmic.200400960

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    Bypassing the kinetic trap of serpin protein folding by loop extension

    Protein Science

    Volume 9, Issue 8, 2000, Pages: 1497–1502, Hana Im, Hee-Young Ahn and Myeong-Hee Yu

    Version of Record online : 31 DEC 2008, DOI: 10.1110/ps.9.8.1497

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    Increased risk of chronic liver failure in adults with heterozygous α-antitrypsin deficiency

    Hepatology

    Volume 28, Issue 4, October 1998, Pages: 1058–1063, Ivo W. Graziadei, Jacob J. Joseph, Russell H. Wiesner, Terry M. Therneau, Kenneth P. Batts and Michael K. Porayko

    Version of Record online : 30 DEC 2003, DOI: 10.1002/hep.510280421

  14. The Jaundiced Baby

    Diseases of the Liver and Biliary System in Children, Second Edition

    Deirdre A. Kelly, Pages: 35–73, 2007

    Published Online : 26 OCT 2007, DOI: 10.1002/9780470987049.ch4

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    Role of Lys335 in the metastability and function of inhibitory serpins

    Protein Science

    Volume 9, Issue 5, 2000, Pages: 934–941, Hana Im and Myeong-Hee Yu

    Version of Record online : 31 DEC 2008, DOI: 10.1110/ps.9.5.934

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    pH-dependent stability of neuroserpin is mediated by histidines 119 and 138; Implications for the control of β-sheet A and polymerization

    Protein Science

    Volume 19, Issue 2, February 2010, Pages: 220–228, Didier Belorgey, Peter Hägglöf, Maki Onda and David A. Lomas

    Version of Record online : 1 DEC 2009, DOI: 10.1002/pro.299

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    Cleaved antitrypsin polymers at atomic resolution

    Protein Science

    Volume 9, Issue 2, 2000, Pages: 417–420, Michelle A. Dunstone, Jamie Rossjohn, Susanne C. Feil, Michael W. Parker, Weiwen Dai, James C. Whisstock, Robert N. Pike, Stephen P. Bottomley and Bernard F. Le Bonniec

    Version of Record online : 31 DEC 2008, DOI: 10.1110/ps.9.2.417

  18. Serine proteinase inhibitor therapy in α1-antitrypsin inhibitor deficiency and cystic fibrosis

    Pediatric Pulmonology

    Volume 28, Issue 5, November 1999, Pages: 363–375, Gerd Döring

    Version of Record online : 26 OCT 1999, DOI: 10.1002/(SICI)1099-0496(199911)28:5<363::AID-PPUL9>3.0.CO;2-#

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    A Cure for Traffic Jams: Small Molecule Chaperones in the Endoplasmic Reticulum

    Traffic

    Volume 5, Issue 11, November 2004, Pages: 815–820, Karin Römisch

    Version of Record online : 14 SEP 2004, DOI: 10.1111/j.1600-0854.2004.00231.x

  20. Genetic diversity of the alpha-1-antitrypsin gene in Africans identified using a novel genotyping assay

    Human Mutation

    Volume 22, Issue 1, July 2003, Pages: 59–66, Vanessa M. Hayes

    Version of Record online : 4 JUN 2003, DOI: 10.1002/humu.10231