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There are 13418 results for: content related to: Membrane and surface interactions of Alzheimer’s Aβ peptide – insights into the mechanism of cytotoxicity

  1. β-Amyloid Therapeutic Strategies for Alzheimer's Disease

    Standard Article

    Burger's Medicinal Chemistry and Drug Discovery

    Bruno P. Imbimbo and Francesca Speroni

    Published Online : 14 OCT 2005, DOI: 10.1002/0471266949.bmc112

  2. You have full text access to this OnlineOpen article
    Altered γ-secretase activity in mild cognitive impairment and Alzheimer's disease

    EMBO Molecular Medicine

    Volume 4, Issue 4, April 2012, Pages: 344–352, Nobuto Kakuda, Mikio Shoji, Hiroyuki Arai, Katsutoshi Furukawa, Takeshi Ikeuchi, Kohei Akazawa, Mako Takami, Hiroyuki Hatsuta, Shigeo Murayama, Yasuhiro Hashimoto, Masakazu Miyajima, Hajime Arai, Yu Nagashima, Haruyasu Yamaguchi, Ryozo Kuwano, Kazuhiro Nagaike, Yasuo Ihara and the Japanese Alzheimer's Disease Neuroimaging Initiative

    Version of Record online : 21 FEB 2012, DOI: 10.1002/emmm.201200214

  3. Age and amyloid effects on human central nervous system amyloid-beta kinetics

    Annals of Neurology

    Volume 78, Issue 3, September 2015, Pages: 439–453, Bruce W. Patterson, Donald L. Elbert, Kwasi G. Mawuenyega, Tom Kasten, Vitaliy Ovod, Shengmei Ma, Chengjie Xiong, Robert Chott, Kevin Yarasheski, Wendy Sigurdson, Lily Zhang, Alison Goate, Tammie Benzinger, John C. Morris, David Holtzman and Randall J. Bateman

    Version of Record online : 20 JUL 2015, DOI: 10.1002/ana.24454

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    Cross-seeding between Aβ40 and Aβ42 in Alzheimer's disease

    FEBS Letters

    Volume 591, Issue 1, January 2017, Pages: 177–185, Joyce Tran, Dennis Chang, Frederick Hsu, Hongsu Wang and Zhefeng Guo

    Version of Record online : 29 DEC 2016, DOI: 10.1002/1873-3468.12526

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    The coexistence of an equal amount of Alzheimer's amyloid-β 40 and 42 forms structurally stable and toxic oligomers through a distinct pathway

    The FEBS Journal

    Volume 281, Issue 11, June 2014, Pages: 2674–2687, Yu-Jen Chang and Yun-Ru Chen

    Version of Record online : 6 MAY 2014, DOI: 10.1111/febs.12813

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    Inhibition of Alzheimer’s amyloid toxicity with a tricyclic pyrone molecule in vitro and in vivo

    Journal of Neurochemistry

    Volume 108, Issue 4, February 2009, Pages: 1097–1108, Hyun-Seok Hong, Sandeep Rana, Lydia Barrigan, Aibin Shi, Yi Zhang, Feimeng Zhou, Lee-Way Jin and Duy H. Hua

    Version of Record online : 25 DEC 2008, DOI: 10.1111/j.1471-4159.2008.05866.x

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    Membrane-bound tetramer and trimer Aβ oligomeric species correlate with toxicity towards cultured neurons

    Journal of Neurochemistry

    Volume 136, Issue 3, February 2016, Pages: 594–608, Metta K. Jana, Roberto Cappai, Chi L. L. Pham and Giuseppe D. Ciccotosto

    Version of Record online : 19 JAN 2016, DOI: 10.1111/jnc.13443

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    Alzheimer's Aβ42 and Aβ40 peptides form interlaced amyloid fibrils

    Journal of Neurochemistry

    Volume 126, Issue 3, August 2013, Pages: 305–311, Lei Gu and Zhefeng Guo

    Version of Record online : 12 MAR 2013, DOI: 10.1111/jnc.12202

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    The correlation between neurotoxicity, aggregative ability and secondary structure studied by sequence truncated Aβ peptides

    FEBS Letters

    Volume 581, Issue 6, March 20, 2007, Pages: 1161–1165, M.Q. Liao, Y.J. Tzeng, Lea Y.X. Chang, H.B. Huang, T.H. Lin, C.L. Chyan and Y.C. Chen

    Version of Record online : 20 FEB 2007, DOI: 10.1016/j.febslet.2007.02.026

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    Novel APP/Aβ mutation K16N produces highly toxic heteromeric Aβ oligomers

    EMBO Molecular Medicine

    Volume 4, Issue 7, July 2012, Pages: 647–659, Daniela Kaden, Anja Harmeier, Christoph Weise, Lisa M. Munter, Veit Althoff, Benjamin R. Rost, Peter W. Hildebrand, Dietmar Schmitz, Michael Schaefer, Rudi Lurz, Sabine Skodda, Raina Yamamoto, Sönke Arlt, Ulrich Finckh and Gerd Multhaup

    Version of Record online : 19 APR 2012, DOI: 10.1002/emmm.201200239

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    The turn formation at positions 22 and 23 in the 42-mer amyloid β peptide: The emerging role in the pathogenesis of Alzheimer's disease

    Geriatrics & Gerontology International

    Volume 10, Issue s1, July 2010, Pages: S169–S179, Kazuma Murakami, Yuichi Masuda, Takuji Shirasawa, Takahiko Shimizu and Kazuhiro Irie

    Version of Record online : 2 JUN 2010, DOI: 10.1111/j.1447-0594.2010.00598.x

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    Co-incorporation of Aβ40 and Aβ42 to form mixed pre-fibrillar aggregates

    European Journal of Biochemistry

    Volume 270, Issue 4, February 2003, Pages: 654–663, David Frost, Paul M Gorman, Christopher M. Yip and Avijit Chakrabartty

    Version of Record online : 24 JAN 2003, DOI: 10.1046/j.1432-1033.2003.03415.x

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    Modulation of β-amyloid metabolism by non-steroidal anti-inflammatory drugs in neuronal cell cultures

    Journal of Neurochemistry

    Volume 88, Issue 2, January 2004, Pages: 337–348, Laura Gasparini, Laura Rusconi, Huaxi Xu, Piero Del Soldato and Ennio Ongini

    Version of Record online : 23 DEC 2003, DOI: 10.1111/j.1471-4159.2004.02154.x

  14. High mobility group box protein-1 inhibits microglial Aβ clearance and enhances Aβ neurotoxicity

    Journal of Neuroscience Research

    Volume 78, Issue 6, 15 December 2004, Pages: 880–891, Kazuyuki Takata, Yoshihisa Kitamura, Daiju Tsuchiya, Toshiyuki Kawasaki, Takashi Taniguchi and Shun Shimohama

    Version of Record online : 21 OCT 2004, DOI: 10.1002/jnr.20340

  15. You have full text access to this OnlineOpen article
    A critique of the drug discovery and phase 3 clinical programs targeting the amyloid hypothesis for Alzheimer disease

    Annals of Neurology

    Volume 76, Issue 2, August 2014, Pages: 185–205, Eric Karran and John Hardy

    Version of Record online : 2 JUL 2014, DOI: 10.1002/ana.24188

  16. Amyloid-β induces sleep fragmentation that is rescued by fatty acid binding proteins in Drosophila

    Journal of Neuroscience Research

    Jason R. Gerstner, Olivia Lenz, William M. Vanderheyden, May T. Chan, Cory Pfeiffenberger and Allan I. Pack

    Version of Record online : 19 JUN 2016, DOI: 10.1002/jnr.23778

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    A presenilin-independent aspartyl protease prefers the γ-42 site cleavage

    Journal of Neurochemistry

    Volume 96, Issue 1, January 2006, Pages: 118–125, Ming-Tain Lai, Ming-Chih Crouthamel, Jillian DiMuzio, Beth Lynn Pietrak, Dorit B. Donoviel, Alan Bernstein, Stephen J. Gardell, Yue-Ming Li and Daria Hazuda

    Version of Record online : 21 NOV 2005, DOI: 10.1111/j.1471-4159.2005.03528.x

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    An apolipoprotein E4 fragment can promote intracellular accumulation of amyloid peptide beta 42

    Journal of Neurochemistry

    Volume 115, Issue 4, November 2010, Pages: 873–884, Ioannis Dafnis, Efstratios Stratikos, Athina Tzinia, Effie C. Tsilibary, Vassilis I. Zannis and Angeliki Chroni

    Version of Record online : 20 APR 2010, DOI: 10.1111/j.1471-4159.2010.06756.x

  19. Conversion of Aβ43 to Aβ40 by the successive action of angiotensin-converting enzyme 2 and angiotensin-converting enzyme

    Journal of Neuroscience Research

    Volume 92, Issue 9, September 2014, Pages: 1178–1186, Shuyu Liu, Junjun Liu, Yukie Miura, Chiaki Tanabe, Tomoji Maeda, Yasuo Terayama, Anthony J. Turner, Kun Zou and Hiroto Komano

    Version of Record online : 14 MAY 2014, DOI: 10.1002/jnr.23404

  20. You have free access to this content
    Cross-seeding effects of amyloid β-protein and α-synuclein

    Journal of Neurochemistry

    Volume 122, Issue 5, September 2012, Pages: 883–890, Kenjiro Ono, Ryoichi Takahashi, Tokuhei Ikeda and Masahito Yamada

    Version of Record online : 23 JUL 2012, DOI: 10.1111/j.1471-4159.2012.07847.x