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There are 14102 results for: content related to: Mutant telomerase RNAs induce DNA damage and apoptosis via the TRF2-ATM pathway in telomerase-overexpressing primary fibroblasts

  1. You have free access to this content
    The function of classical and alternative non-homologous end-joining pathways in the fusion of dysfunctional telomeres

    The EMBO Journal

    Volume 29, Issue 15, August 4, 2010, Pages: 2598–2610, Rekha Rai, Hong Zheng, Hua He, Ying Luo, Asha Multani, Phillip B Carpenter and Sandy Chang

    Article first published online : 29 JUN 2010, DOI: 10.1038/emboj.2010.142

  2. You have full text access to this OnlineOpen article
    Essential role for the TRF2 telomere protein in adult skin homeostasis

    Aging Cell

    Volume 13, Issue 4, August 2014, Pages: 656–668, Paula Martínez, Iole Ferrara-Romeo, Juana M. Flores and Maria A. Blasco

    Article first published online : 14 APR 2014, DOI: 10.1111/acel.12221

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    Requirement of DDX39 DEAD box RNA helicase for genome integrity and telomere protection

    Aging Cell

    Volume 10, Issue 4, August 2011, Pages: 557–571, Hyun Hee Yoo and In Kwon Chung

    Article first published online : 25 APR 2011, DOI: 10.1111/j.1474-9726.2011.00696.x

  4. RNF4 interacts with both SUMO and nucleosomes to promote the DNA damage response

    EMBO reports

    Volume 15, Issue 5, May 2014, Pages: 601–608, Lynda M Groocock, Minghua Nie, John Prudden, Davide Moiani, Tao Wang, Anton Cheltsov, Robert P Rambo, Andrew S Arvai, Chiharu Hitomi, John A Tainer, Karolin Luger, J Jefferson P Perry, Eros Lazzerini-Denchi and Michael N Boddy

    Article first published online : 8 APR 2014, DOI: 10.1002/embr.201338369

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    A new pathway that regulates 53BP1 stability implicates Cathepsin L and vitamin D in DNA repair

    The EMBO Journal

    Volume 30, Issue 16, August 17, 2011, Pages: 3383–3396, Ignacio Gonzalez-Suarez, Abena B Redwood, David A Grotsky, Martin A Neumann, Emily H-Y Cheng, Colin L Stewart, Adriana Dusso and Susana Gonzalo

    Article first published online : 12 JUL 2011, DOI: 10.1038/emboj.2011.225

  6. You have full text access to this OnlineOpen article
    Mitosis, double strand break repair, and telomeres: A view from the end

    BioEssays

    Volume 36, Issue 11, November 2014, Pages: 1054–1061, Anthony J. Cesare

    Article first published online : 29 AUG 2014, DOI: 10.1002/bies.201400104

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    Human RAP1 inhibits non-homologous end joining at telomeres

    The EMBO Journal

    Volume 28, Issue 21, November 4, 2009, Pages: 3390–3399, Jay Sarthy, Nancy S Bae, Jonathan Scrafford and Peter Baumann

    Article first published online : 17 SEP 2009, DOI: 10.1038/emboj.2009.275

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    TRF2 dysfunction elicits DNA damage responses associated with senescence in proliferating neural cells and differentiation of neurons

    Journal of Neurochemistry

    Volume 97, Issue 2, April 2006, Pages: 567–581, Peisu Zhang, Katsutoshi Furukawa, Patricia L. Opresko, Xiangru Xu, Vilhelm A. Bohr and Mark P. Mattson

    Article first published online : 15 MAR 2006, DOI: 10.1111/j.1471-4159.2006.03779.x

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    Corrigendum

    FEBS Journal

    Volume 279, Issue 2, January 2012, Page: 358,

    Article first published online : 30 NOV 2011, DOI: 10.1111/j.1742-4658.2011.08427.x

    This article corrects:
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    Different telomere damage signaling pathways in human and mouse cells

    The EMBO Journal

    Volume 21, Issue 16, August 15, 2002, Pages: 4338–4348, Agata Smogorzewska and Titia de Lange

    Article first published online : 15 AUG 2002, DOI: 10.1093/emboj/cdf433

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    Novel roles for A-type lamins in telomere biology and the DNA damage response pathway

    The EMBO Journal

    Volume 28, Issue 16, August 19, 2009, Pages: 2414–2427, Ignacio Gonzalez-Suarez, Abena B Redwood, Stephanie M Perkins, Bart Vermolen, Daniel Lichtensztejin, David A Grotsky, Lucia Morgado-Palacin, Eric J Gapud, Barry P Sleckman, Teresa Sullivan, Julien Sage, Colin L Stewart, Sabine Mai and Susana Gonzalo

    Article first published online : 23 JUL 2009, DOI: 10.1038/emboj.2009.196

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    POT1 protects telomeres from a transient DNA damage response and determines how human chromosomes end

    The EMBO Journal

    Volume 24, Issue 14, July 20, 2005, Pages: 2667–2678, Dirk Hockemeyer, Agnel J Sfeir, Jerry W Shay, Woodring E Wright and Titia de Lange

    Article first published online : 23 JUN 2005, DOI: 10.1038/sj.emboj.7600733

  13. Heat shock-induced dissociation of TRF2 from telomeres does not initiate a telomere-dependent DNA damage response

    Cell Biology International

    Volume 38, Issue 5, May 2014, Pages: 675–681, Nadezhda V. Petrova, Artem K. Velichko, Omar L. Kantidze and Sergey V. Razin

    Article first published online : 6 FEB 2014, DOI: 10.1002/cbin.10252

  14. A three-dimensional colocalization RNA interference screening platform to elucidate the alternative lengthening of telomeres pathway

    Biotechnology Journal

    Volume 7, Issue 1, January 2012, Pages: 103–116, Sarah Osterwald, Stefan Wörz, Jürgen Reymann, Frank Sieckmann, Karl Rohr, Holger Erfle and Dr. Karsten Rippe

    Article first published online : 7 JUN 2011, DOI: 10.1002/biot.201000474

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    Involvement of human ORC and TRF2 in pre-replication complex assembly at telomeres

    Genes to Cells

    Volume 13, Issue 10, October 2008, Pages: 1045–1059, Yasutoshi Tatsumi, Kai Ezura, Kazumasa Yoshida, Takashi Yugawa, Mako Narisawa-Saito, Tohru Kiyono, Satoshi Ohta, Chikashi Obuse and Masatoshi Fujita

    Article first published online : 29 AUG 2008, DOI: 10.1111/j.1365-2443.2008.01224.x

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    53BP1 promotes ATM activity through direct interactions with the MRN complex

    The EMBO Journal

    Volume 29, Issue 3, February 3, 2010, Pages: 574–585, Ji-Hoon Lee, Aaron A Goodarzi, Penny A Jeggo and Tanya T Paull

    Article first published online : 10 DEC 2009, DOI: 10.1038/emboj.2009.372

  17. You have full text access to this OnlineOpen article
    The role of ATM and 53BP1 as predictive markers in cervical cancer

    International Journal of Cancer

    Volume 131, Issue 9, 1 November 2012, Pages: 2056–2066, Frank Roossink, Hylke W. Wieringa, Maartje G. Noordhuis, Klaske A. ten Hoor, Mirjam Kok, Lorian Slagter-Menkema, Harry Hollema, Geertruida H. de Bock, Elisabeth Pras, Elisabeth G.E. de Vries, Steven de Jong, Ate G.J. van der Zee, Ed Schuuring, G. Bea A. Wisman and Marcel A.T.M. van Vugt

    Article first published online : 29 MAR 2012, DOI: 10.1002/ijc.27488

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    Comparison of BRCT domains of BRCA1 and 53BP1: A biophysical analysis

    Protein Science

    Volume 13, Issue 3, March 2004, Pages: 617–625, Caroline M.S. Ekblad, Assaf Friedler, Dmitry Veprintsev, Richard L. Weinberg and Laura S. Itzhaki

    Article first published online : 1 JAN 2009, DOI: 10.1110/ps.03461404

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    Oncogene-induced telomere dysfunction enforces cellular senescence in human cancer precursor lesions

    The EMBO Journal

    Volume 31, Issue 13, June 29, 2012, Pages: 2839–2851, Anitha Suram, Jessica Kaplunov, Priyanka L Patel, Haihe Ruan, Aurora Cerutti, Virginia Boccardi, Marzia Fumagalli, Raffaella Di Micco, Neena Mirani, Resham Lal Gurung, Manoor Prakash Hande, Fabrizio d'Adda di Fagagna and Utz Herbig

    Article first published online : 8 MAY 2012, DOI: 10.1038/emboj.2012.132

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    REST-dependent expression of TRF2 renders non-neuronal cancer cells resistant to DNA damage during oxidative stress

    International Journal of Cancer

    Volume 132, Issue 4, 15 February 2013, Pages: 832–842, Jung-Hee Kwon, Ji Hye Shin, Eung-Sam Kim, Namgyu Lee, Jin Young Park, Bonik Samuel Koo, Sun Mi Hong, Chang Wook Park and Kwan Yong Choi

    Article first published online : 7 AUG 2012, DOI: 10.1002/ijc.27741