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There are 31033 results for: content related to: Protein engineering to stabilize soluble amyloid β-protein aggregates for structural and functional studies

  1. You have free access to this content
    Sensitive ELISA detection of amyloid-β protofibrils in biological samples

    Journal of Neurochemistry

    Volume 103, Issue 1, October 2007, Pages: 334–345, Hillevi Englund, Dag Sehlin, Ann-Sofi Johansson, Lars N. G. Nilsson, Pär Gellerfors, Staffan Paulie, Lars Lannfelt and Frida Ekholm Pettersson

    Article first published online : 9 JUN 2007, DOI: 10.1111/j.1471-4159.2007.04759.x

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    Physiochemical characterization of the Alzheimer's disease-related peptides Aβ1–42Arctic and Aβ1–42wt

    FEBS Journal

    Volume 273, Issue 12, June 2006, Pages: 2618–2630, Ann-Sofi Johansson, Fredrik Berglind-Dehlin, Göran Karlsson, Katarina Edwards, Pär Gellerfors and Lars Lannfelt

    Article first published online : 19 MAY 2006, DOI: 10.1111/j.1742-4658.2006.05263.x

  3. Structure and assembly–disassembly properties of wild-type transthyretin amyloid protofibrils observed with atomic force microscopy

    Journal of Molecular Recognition

    Volume 24, Issue 3, May/June 2011, Pages: 467–476, Ricardo H. Pires, Maria J. Saraiva, Ana M. Damas and Miklós S. Z. Kellermayer

    Article first published online : 4 APR 2011, DOI: 10.1002/jmr.1112

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    Amyloid-β protofibril levels correlate with spatial learning in Arctic Alzheimer’s disease transgenic mice

    FEBS Journal

    Volume 276, Issue 4, February 2009, Pages: 995–1006, Anna Lord, Hillevi Englund, Linda Söderberg, Stina Tucker, Fredrik Clausen, Lars Hillered, Marcia Gordon, Dave Morgan, Lars Lannfelt, Frida E. Pettersson and Lars N. G. Nilsson

    Article first published online : 7 JAN 2009, DOI: 10.1111/j.1742-4658.2008.06836.x

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    Translating research on brain aging into public health: a new type of immunotherapy for Alzheimer's disease

    Nutrition Reviews

    Volume 68, Issue s2, December 2010, Pages: S128–S134, Lars Lannfelt, Frida Ekholm Pettersson and Lars NG Nilsson

    Article first published online : 23 NOV 2010, DOI: 10.1111/j.1753-4887.2010.00347.x

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    Docosahexaenoic acid stabilizes soluble amyloid-β protofibrils and sustains amyloid-β-induced neurotoxicity in vitro

    FEBS Journal

    Volume 274, Issue 4, February 2007, Pages: 990–1000, Ann-Sofi Johansson, Anita Garlind, Fredrik Berglind-Dehlin, Göran Karlsson, Katarina Edwards, Pär Gellerfors, Frida Ekholm-Pettersson, Jan Palmblad and Lars Lannfelt

    Article first published online : 12 JAN 2007, DOI: 10.1111/j.1742-4658.2007.05647.x

  7. A Hexameric Peptide Barrel as Building Block of Amyloid-β Protofibrils

    Angewandte Chemie

    Volume 126, Issue 47, November 17, 2014, Pages: 12970–12974, Dr. Christofer Lendel, Dr. Morten Bjerring, Dr. Anatoly Dubnovitsky, Robert T. Kelly, Dr. Andrei Filippov, Prof. Dr. Oleg N. Antzutkin, Prof. Dr. Niels Chr. Nielsen and Prof. Dr. Torleif Härd

    Article first published online : 26 SEP 2014, DOI: 10.1002/ange.201406357

  8. A Hexameric Peptide Barrel as Building Block of Amyloid-β Protofibrils

    Angewandte Chemie International Edition

    Volume 53, Issue 47, November 17, 2014, Pages: 12756–12760, Dr. Christofer Lendel, Dr. Morten Bjerring, Dr. Anatoly Dubnovitsky, Robert T. Kelly, Dr. Andrei Filippov, Prof. Dr. Oleg N. Antzutkin, Prof. Dr. Niels Chr. Nielsen and Prof. Dr. Torleif Härd

    Article first published online : 26 SEP 2014, DOI: 10.1002/anie.201406357

  9. You have full text access to this OnlineOpen article
    Lipids revert inert Aβ amyloid fibrils to neurotoxic protofibrils that affect learning in mice

    The EMBO Journal

    Volume 27, Issue 1, January 9, 2008, Pages: 224–233, Ivo Cristiano Martins, Inna Kuperstein, Hannah Wilkinson, Elke Maes, Mieke Vanbrabant, Wim Jonckheere, Patrick Van Gelder, Dieter Hartmann, Rudi D'Hooge, Bart De Strooper, Joost Schymkowitz and Frederic Rousseau

    Article first published online : 6 DEC 2007, DOI: 10.1038/sj.emboj.7601953

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    Monoclonal antibodies selective for α-synuclein oligomers/protofibrils recognize brain pathology in Lewy body disorders and α-synuclein transgenic mice with the disease-causing A30P mutation

    Journal of Neurochemistry

    Volume 126, Issue 1, July 2013, Pages: 131–144, Therese Fagerqvist, Veronica Lindström, Eva Nordström, Anna Lord, Stina M. E. Tucker, Xingjian Su, Charlotte Sahlin, Alex Kasrayan, Jessica Andersson, Hedvig Welander, Thomas Näsström, Mats Holmquist, Heinrich Schell, Philipp J. Kahle, Hannu Kalimo, Christer Möller, Pär Gellerfors, Lars Lannfelt, Joakim Bergström and Martin Ingelsson

    Article first published online : 27 FEB 2013, DOI: 10.1111/jnc.12175

  11. Characterizing Methyl-Bearing Side Chain Contacts and Dynamics Mediating Amyloid β Protofibril Interactions Using 13Cmethyl-DEST and Lifetime Line Broadening

    Angewandte Chemie

    Volume 126, Issue 39, September 22, 2014, Pages: 10513–10517, Dr. Nicolas L. Fawzi, Dr. David S. Libich, Dr. Jinfa Ying, Dr. Vitali Tugarinov and Dr. G. Marius Clore

    Article first published online : 11 AUG 2014, DOI: 10.1002/ange.201405180

  12. Characterizing Methyl-Bearing Side Chain Contacts and Dynamics Mediating Amyloid β Protofibril Interactions Using 13Cmethyl-DEST and Lifetime Line Broadening

    Angewandte Chemie International Edition

    Volume 53, Issue 39, September 22, 2014, Pages: 10345–10349, Dr. Nicolas L. Fawzi, Dr. David S. Libich, Dr. Jinfa Ying, Dr. Vitali Tugarinov and Dr. G. Marius Clore

    Article first published online : 11 AUG 2014, DOI: 10.1002/anie.201405180

  13. Structure and elasticity of desmin protofibrils explored with scanning force microscopy

    Journal of Molecular Recognition

    Volume 24, Issue 6, November/December 2011, Pages: 1095–1104, Balázs Kiss, Pál Röhlich and Miklós S. Z. Kellermayer

    Article first published online : 10 OCT 2011, DOI: 10.1002/jmr.1158

  14. Control of Amyloid β-Peptide Protofibril Formation by a Designed Template Assembly

    Angewandte Chemie International Edition

    Volume 45, Issue 17, April 21, 2006, Pages: 2699–2702, Gunnar T. Dolphin, Pascal Dumy and Julian Garcia

    Article first published online : 23 MAR 2006, DOI: 10.1002/anie.200600395

  15. Control of Amyloid β-Peptide Protofibril Formation by a Designed Template Assembly

    Angewandte Chemie

    Volume 118, Issue 17, April 21, 2006, Pages: 2765–2768, Gunnar T. Dolphin, Pascal Dumy and Julian Garcia

    Article first published online : 23 MAR 2006, DOI: 10.1002/ange.200600395

  16. Self-assembly of regenerated silk fibroin from random coil nanostructures to antiparallel β-sheet nanostructures

    Biopolymers

    Volume 101, Issue 12, December 2014, Pages: 1181–1192, Jian Zhong, Mengjia Ma, Wenying Li, Juan Zhou, Zhiqiang Yan and Dannong He

    Article first published online : 23 SEP 2014, DOI: 10.1002/bip.22532

  17. You have full text access to this Open Access content
    High-molecular weight Aβ oligomers and protofibrils are the predominant Aβ species in the native soluble protein fraction of the AD brain

    Journal of Cellular and Molecular Medicine

    Volume 16, Issue 2, February 2012, Pages: 287–295, Ajeet Rijal Upadhaya, Irina Lungrin, Haruyasu Yamaguchi, Marcus Fändrich and Dietmar Rudolf Thal

    Article first published online : 27 JAN 2012, DOI: 10.1111/j.1582-4934.2011.01306.x

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    Inhibition of Alzheimer’s amyloid toxicity with a tricyclic pyrone molecule in vitro and in vivo

    Journal of Neurochemistry

    Volume 108, Issue 4, February 2009, Pages: 1097–1108, Hyun-Seok Hong, Sandeep Rana, Lydia Barrigan, Aibin Shi, Yi Zhang, Feimeng Zhou, Lee-Way Jin and Duy H. Hua

    Article first published online : 25 DEC 2008, DOI: 10.1111/j.1471-4159.2008.05866.x

  19. Studies of the growth, evolution, and self-aggregation of β-amyloid fibrils using tapping-mode atomic force microscopy

    Microscopy Research and Technique

    Volume 74, Issue 7, July 2011, Pages: 699–708, Wilson K. Serem, Cyrus K. Bett, Johnpeter N. Ngunjiri and Jayne C. Garno

    Article first published online : 3 NOV 2010, DOI: 10.1002/jemt.20940

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    Paradigm shifts in Alzheimer's disease and other neurodegenerative disorders: The emerging role of oligomeric assemblies

    Journal of Neuroscience Research

    Volume 69, Issue 5, 1 September 2002, Pages: 567–577, Marina D. Kirkitadze, Gal Bitan and David B. Teplow

    Article first published online : 5 AUG 2002, DOI: 10.1002/jnr.10328