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There are 11725 results for: content related to: Biological validation that SF3b is a target of the antitumor macrolide pladienolide

  1. Splice factor mutations and alternative splicing as drivers of hematopoietic malignancy

    Immunological Reviews

    Volume 263, Issue 1, January 2015, Pages: 257–278, Christopher N. Hahn, Parvathy Venugopal, Hamish S.  Scott and Devendra K. Hiwase

    Version of Record online : 15 DEC 2014, DOI: 10.1111/imr.12241

  2. You have full text access to this OnlineOpen article
    SF3B1 mutations constitute a novel therapeutic target in breast cancer

    The Journal of Pathology

    Volume 235, Issue 4, March 2015, Pages: 571–580, Sarah L Maguire, Andri Leonidou, Patty Wai, Caterina Marchiò, Charlotte KY Ng, Anna Sapino, Anne-Vincent Salomon, Jorge S Reis-Filho, Britta Weigelt and Rachael C Natrajan

    Version of Record online : 22 DEC 2014, DOI: 10.1002/path.4483

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    Splicing factor mutations and cancer

    Wiley Interdisciplinary Reviews: RNA

    Volume 5, Issue 4, July/August 2014, Pages: 445–459, Kenichi Yoshida and Seishi Ogawa

    Version of Record online : 12 FEB 2014, DOI: 10.1002/wrna.1222

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    SF3B1 mutations in patients with myelodysplastic syndromes: The mutation is stable during disease evolution

    American Journal of Hematology

    Volume 89, Issue 8, August 2014, Pages: E109–E115, Chien-Chin Lin, Hsin-An Hou, Wen-Chien Chou, Yuan-Yeh Kuo, Shang-Ju Wu, Chieh-Yu Liu, Chien-Yuan Chen, Mei-Hsuan Tseng, Chi-Fei Huang, Fen-Yu Lee, Ming-Chih Liu, Chia-Wen Liu, Jih-Luh Tang, Ming Yao, Shang-Yi Huang, Szu-Chun Hsu, Bor-Sheng Ko, Woei Tsay, Yao-Chang Chen and Hwei-Fang Tien

    Version of Record online : 28 APR 2014, DOI: 10.1002/ajh.23734

  5. Modulating splicing with small molecular inhibitors of the spliceosome

    Wiley Interdisciplinary Reviews: RNA

    Kerstin A. Effenberger, Veronica K. Urabe and Melissa S. Jurica

    Version of Record online : 21 JUL 2016, DOI: 10.1002/wrna.1381

  6. You have full text access to this OnlineOpen article
    Aberrant splicing of genes involved in haemoglobin synthesis and impaired terminal erythroid maturation in SF3B1 mutated refractory anaemia with ring sideroblasts

    British Journal of Haematology

    Volume 171, Issue 4, November 2015, Pages: 478–490, Simona Conte, Shintaro Katayama, Liselotte Vesterlund, Mohsen Karimi, Marios Dimitriou, Monika Jansson, Teresa Mortera-Blanco, Per Unneberg, Elli Papaemmanuil, Birgitta Sander, Tiina Skoog, Peter Campbell, Julian Walfridsson, Juha Kere and Eva Hellström-Lindberg

    Version of Record online : 10 AUG 2015, DOI: 10.1111/bjh.13610

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    Mutational analysis of splicing machinery genes SF3B1, U2AF1 and SRSF2 in myelodysplasia and other common tumors

    International Journal of Cancer

    Volume 133, Issue 1, July 2013, Pages: 260–265, Eun Mi Je, Nam Jin Yoo, Yoo Jin Kim, Myung Shin Kim and Sug Hyung Lee

    Version of Record online : 5 FEB 2013, DOI: 10.1002/ijc.28011

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    Refractory anemia with ring sideroblasts and RARS with thrombocytosis

    American Journal of Hematology

    Volume 90, Issue 6, June 2015, Pages: 549–559, Mrinal M. Patnaik and Ayalew Tefferi

    Version of Record online : 19 MAY 2015, DOI: 10.1002/ajh.24038

  9. Recent advances in the understanding of myelodysplastic syndromes with ring sideroblasts

    British Journal of Haematology

    Volume 174, Issue 6, September 2016, Pages: 847–858, Luca Malcovati and Mario Cazzola

    Version of Record online : 8 JUL 2016, DOI: 10.1111/bjh.14215

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    Defects in spliceosomal machinery: a new pathway of leukaemogenesis

    British Journal of Haematology

    Volume 158, Issue 2, July 2012, Pages: 165–173, Jaroslaw P. Maciejewski and Richard A. Padgett

    Version of Record online : 18 MAY 2012, DOI: 10.1111/j.1365-2141.2012.09158.x

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    The molecular pathogenesis of the myelodysplastic syndromes

    European Journal of Haematology

    Volume 95, Issue 1, July 2015, Pages: 3–15, Andrea Pellagatti and Jacqueline Boultwood

    Version of Record online : 20 FEB 2015, DOI: 10.1111/ejh.12515

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    IX. Chronic lymphocytic leukaemia: New genetic markers as prognostic factors

    Hematological Oncology

    Volume 31, Issue S1, June 2013, Pages: 57–59, Davide Rossi

    Version of Record online : 17 JUN 2013, DOI: 10.1002/hon.2068

  13. You have full text access to this OnlineOpen article
    Pharmacodynamic assays to facilitate preclinical and clinical development of pre-mRNA splicing modulatory drug candidates

    Pharmacology Research & Perspectives

    Volume 3, Issue 4, August 2015, Yihui Shi, Amanda S. Joyner, William Shadrick, Gustavo Palacios, Chandraiah Lagisetti, Philip M. Potter, Lidia C. Sambucetti, Stefan Stamm and Thomas R. Webb

    Version of Record online : 26 JUN 2015, DOI: 10.1002/prp2.158

  14. Complex assembly mechanism and an RNA-binding mode of the human p14-SF3b155 spliceosomal protein complex identified by NMR solution structure and functional analyses

    Proteins: Structure, Function, and Bioinformatics

    Volume 71, Issue 4, June 2008, Pages: 1617–1636, Kanako Kuwasako, Naoshi Dohmae, Mio Inoue, Mikako Shirouzu, Seiichi Taguchi, Peter Güntert, Bertrand Séraphin, Yutaka Muto and Shigeyuki Yokoyama

    Version of Record online : 12 DEC 2007, DOI: 10.1002/prot.21839

  15. The genomic landscape of chronic lymphocytic leukaemia: biological and clinical implications

    British Journal of Haematology

    Volume 169, Issue 1, April 2015, Pages: 14–31, Jonathan C. Strefford

    Version of Record online : 11 DEC 2014, DOI: 10.1111/bjh.13254

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    Spliceosome mutations involving SRSF2, SF3B1, and U2AF35 in chronic myelomonocytic leukemia: Prevalence, clinical correlates, and prognostic relevance

    American Journal of Hematology

    Volume 88, Issue 3, March 2013, Pages: 201–206, Mrinal M. Patnaik, Terra L. Lasho, Christy M. Finke, Curtis A. Hanson, Janice M. Hodnefield, Ryan A. Knudson, Rhett P. Ketterling, Animesh Pardanani and Ayalew Tefferi

    Version of Record online : 18 JAN 2013, DOI: 10.1002/ajh.23373

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    Validation of the WHO 2016 proposals for Myelodysplastic syndromes patients with the presence of ring sideroblasts but without excess blasts

    British Journal of Haematology

    Yi Li, Rui Cui, Tiejun Qin, Zefeng Xu, Yue Zhang, Wenyu Cai, Wen Cui, Jinqin Liu, Bing Li and Zhijian Xiao

    Version of Record online : 13 JUN 2016, DOI: 10.1111/bjh.14168

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    A novel U2 and U11/U12 snRNP protein that associates with the pre-mRNA branch site

    The EMBO Journal

    Volume 20, Issue 16, August 15, 2001, Pages: 4536–4546, Cindy L. Will, Claudia Schneider, Andrew M. MacMillan, Nikos F. Katopodis, Gitte Neubauer, Matthias Wilm, Reinhard Lührmann and Charles C. Query

    Version of Record online : 15 AUG 2001, DOI: 10.1093/emboj/20.16.4536

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    Chronic lymphocytic leukemia: Time to go past genomics?

    American Journal of Hematology

    Volume 91, Issue 5, May 2016, Pages: 518–528, Damien Roos-Weil, Florence Nguyen-Khac and Olivier A. Bernard

    Version of Record online : 4 APR 2016, DOI: 10.1002/ajh.24301

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    Characterization of novel SF3b and 17S U2 snRNP proteins, including a human Prp5p homologue and an SF3b DEAD-box protein

    The EMBO Journal

    Volume 21, Issue 18, September 16, 2002, Pages: 4978–4988, Cindy L. Will, Henning Urlaub, Tilmann Achsel, Marc Gentzel, Matthias Wilm and Reinhard Lührmann

    Version of Record online : 16 SEP 2002, DOI: 10.1093/emboj/cdf480