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There are 36624 results for: content related to: Signalling by protein phosphatases and drug development: a systems-centred view

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    Small molecule tools for functional interrogation of protein tyrosine phosphatases

    FEBS Journal

    Volume 280, Issue 2, January 2013, Pages: 731–750, Rongjun He, Li-Fan Zeng, Yantao He, Sheng Zhang and Zhong-Yin Zhang

    Article first published online : 16 AUG 2012, DOI: 10.1111/j.1742-4658.2012.08718.x

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    Protein tyrosine phosphatases – from housekeeping enzymes to master regulators of signal transduction

    FEBS Journal

    Volume 280, Issue 2, January 2013, Pages: 346–378, Nicholas K. Tonks

    Article first published online : 17 JAN 2013, DOI: 10.1111/febs.12077

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    Interleukin-6-induced proliferation of pre-B cells mediated by receptor complexes lacking the SHP2/SOCS3 recruitment sites revisited

    European Journal of Biochemistry

    Volume 268, Issue 24, December 2001, Pages: 6401–6407, Kerstin Friederichs, Jochen Schmitz, Manuela Weissenbach, Peter C. Heinrich and Fred Schaper

    Article first published online : 12 JAN 2002, DOI: 10.1046/j.0014-2956.2001.02586.x

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    Protein tyrosine phosphatases: regulatory mechanisms

    FEBS Journal

    Volume 275, Issue 5, March 2008, Pages: 831–847, Jeroen den Hertog, Arne Östman and Frank-D. Böhmer

    Article first published online : 8 FEB 2008, DOI: 10.1111/j.1742-4658.2008.06247.x

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    Protein tyrosine phosphatases: functional inferences from mouse models and human diseases

    FEBS Journal

    Volume 275, Issue 5, March 2008, Pages: 816–830, Wiljan J. A. J. Hendriks, Ari Elson, Sheila Harroch and Andrew W. Stoker

    Article first published online : 8 FEB 2008, DOI: 10.1111/j.1742-4658.2008.06249.x

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    Protein tyrosine phosphatases in health and disease

    FEBS Journal

    Volume 280, Issue 2, January 2013, Pages: 708–730, Wiljan J. A. J. Hendriks, Ari Elson, Sheila Harroch, Rafael Pulido, Andrew Stoker and Jeroen den Hertog

    Article first published online : 1 OCT 2012, DOI: 10.1111/febs.12000

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    Protein tyrosine phosphatase structure–function relationships in regulation and pathogenesis

    FEBS Journal

    Volume 280, Issue 2, January 2013, Pages: 413–431, Frank Böhmer, Stefan Szedlacsek, Lydia Tabernero, Arne Östman and Jeroen den Hertog

    Article first published online : 2 JUL 2012, DOI: 10.1111/j.1742-4658.2012.08655.x

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    A new high affinity binding site for suppressor of cytokine signaling-3 on the erythropoietin receptor

    European Journal of Biochemistry

    Volume 269, Issue 10, May 2002, Pages: 2516–2526, Michael Hörtner, Ulrich Nielsch, Lorenz M. Mayr, Peter C. Heinrich and Serge Haan

    Article first published online : 9 MAY 2002, DOI: 10.1046/j.1432-1033.2002.02916.x

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    Reactivation of oxidized PTP1B and PTEN by thioredoxin 1

    FEBS Journal

    Volume 281, Issue 16, August 2014, Pages: 3545–3558, Ulla Schwertassek, Aftabul Haque, Navasona Krishnan, Romy Greiner, Lars Weingarten, Tobias P. Dick and Nicholas K. Tonks

    Article first published online : 23 JUL 2014, DOI: 10.1111/febs.12898

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    Regulation of ACh receptor clustering by the tyrosine phosphatase Shp2

    Developmental Neurobiology

    Volume 67, Issue 13, November 2007, Pages: 1789–1801, Xiaotao T. Zhao, Yueping K. Qian, Ariel W.S. Chan, Raghavan Madhavan and H. Benjamin Peng

    Article first published online : 20 JUL 2007, DOI: 10.1002/dneu.20556

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    Redox regulation of the protein tyrosine phosphatase PTP1B in cancer cells

    FEBS Journal

    Volume 275, Issue 1, January 2008, Pages: 69–88, Yi-Wei Lou, Yi-Yun Chen, Shu-Fan Hsu, Ren-Kun Chen, Chih-Lei Lee, Kay-Hooi Khoo, Nicholas K. Tonks and Tzu-Ching Meng

    Article first published online : 6 DEC 2007, DOI: 10.1111/j.1742-4658.2007.06173.x

  12. Development of a Plate-Based Assay Platform to Monitor Cellular SHP2 Phosphatase Activity During Erythroid Differentiation

    Journal of the Chinese Chemical Society

    Volume 59, Issue 3, March 2012, Pages: 297–304, Chi-Yuan Chu, Chun-Chen Kuo, Mei-Hsiao Chen, Kuan-Ju Chen, Lee-Chiang Lo and Jing-Jer Lin

    Article first published online : 7 MAR 2012, DOI: 10.1002/jccs.201100725

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    The anti-inflammatory compound BAY-11-7082 is a potent inhibitor of protein tyrosine phosphatases

    FEBS Journal

    Volume 280, Issue 12, June 2013, Pages: 2830–2841, Navasona Krishnan, Gyula Bencze, Philip Cohen and Nicholas K. Tonks

    Article first published online : 9 MAY 2013, DOI: 10.1111/febs.12283

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    Docking proteins

    FEBS Journal

    Volume 277, Issue 21, November 2010, Pages: 4356–4369, Tilman Brummer, Carsten Schmitz-Peiffer and Roger J. Daly

    Article first published online : 30 SEP 2010, DOI: 10.1111/j.1742-4658.2010.07865.x

  15. Src homology phosphotyrosyl phosphatase-2 expression is an independent negative prognostic factor in human breast cancer

    Histopathology

    Volume 63, Issue 1, July 2013, Pages: 74–82, Simone Muenst, Ellen C Obermann, Feng Gao, Daniel Oertli, Carsten T Viehl, Walter P Weber, Timothy Fleming, William E Gillanders and Savas D Soysal

    Article first published online : 15 MAY 2013, DOI: 10.1111/his.12140

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    PTP1B and TCPTP – nonredundant phosphatases in insulin signaling and glucose homeostasis

    FEBS Journal

    Volume 280, Issue 2, January 2013, Pages: 445–458, Tony Tiganis

    Article first published online : 18 APR 2012, DOI: 10.1111/j.1742-4658.2012.08563.x

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    Methods to monitor classical protein-tyrosine phosphatase oxidation

    FEBS Journal

    Volume 280, Issue 2, January 2013, Pages: 459–475, Robert Karisch and Benjamin G. Neel

    Article first published online : 30 MAY 2012, DOI: 10.1111/j.1742-4658.2012.08626.x

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    Different protein turnover of interleukin-6-type cytokine signalling components

    European Journal of Biochemistry

    Volume 265, Issue 1, October (I) 1999, Pages: 251–257, Elmar Siewert, Werner Müller-Esterl, Robin Starr, Peter C. Heinrich and Fred Schaper

    Article first published online : 25 DEC 2001, DOI: 10.1046/j.1432-1327.1999.00719.x

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    Tyrosine phosphatases Shp1 and Shp2 have unique and opposing roles in oligodendrocyte development

    Journal of Neurochemistry

    Volume 113, Issue 1, April 2010, Pages: 200–212, Emory Kuo, Daniel K. Park, Iva D. Tzvetanova, Cindy V. Leiton, Brian S. Cho and Holly Colognato

    Article first published online : 2 FEB 2010, DOI: 10.1111/j.1471-4159.2010.06596.x

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    Calpain-mediated degradation of reversibly oxidized protein-tyrosine phosphatase 1B

    FEBS Journal

    Volume 276, Issue 19, October 2009, Pages: 5622–5633, Antje Trümpler, Bernhard Schlott, Peter Herrlich, Peter A. Greer and Frank-D. Böhmer

    Article first published online : 27 AUG 2009, DOI: 10.1111/j.1742-4658.2009.07255.x