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There are 17102 results for: content related to: Active Site Ring-Opening of a Thiirane Moiety and Picomolar Inhibition of Gelatinases

  1. The Design, Synthesis and Potential Utility of Fluorescence Probes that Target DFG-out Conformation of p38α for High Throughput Screening Binding Assay

    Chemical Biology & Drug Design

    Volume 74, Issue 6, December 2009, Pages: 547–559, Haile Tecle, Frederic Feru, Hu Liu, Cyrille Kuhn, Glen Rennie, Mark Morris, Jiangxing Shao, Alan C. Cheng, Diana Gikunju, Juan Miret, Rocco Coli, Simon (Hualin) Xi, Susan L. Clugston, Simon Low, Steven Kazmirski, Yuan-Hua Ding, Qing Cao, Theresa L. Johnson, Gayatri D. Deshmukh, Jonathan P. DiNitto, Joe C. Wu and Jessie M. English

    Article first published online : 20 OCT 2009, DOI: 10.1111/j.1747-0285.2009.00884.x

  2. Antibacterial Activity, Quantitative Structure–Activity Relationship and Diastereoselective Synthesis of Isoxazolidine Derivatives Via 1,3-Dipolar Cycloaddition of d-glucose Derived Nitrone with Olefin

    Chemical Biology & Drug Design

    Volume 74, Issue 5, November 2009, Pages: 494–506, Munusamy Damodiran, Ponnurengan Malliappan Sivakumar, Rathnasabapathy SenthilKumar, Duraisamy Muralidharan, Bandara Venkata Narasimha Phani Kumar, Mukesh Doble and Paramasivan Thirumalai Perumal

    Article first published online : 28 SEP 2009, DOI: 10.1111/j.1747-0285.2009.00887.x

  3. Cellular Fingerprints: A Novel Approach Using Large-Scale Cancer Cell Line Data for the Identification of Potential Anticancer Agents

    Chemical Biology & Drug Design

    Volume 74, Issue 5, November 2009, Pages: 439–448, Melanie Füllbeck, Mathias Dunkel, Julia Hossbach, Peter T. Daniel and Robert Preissner

    Article first published online : 2 OCT 2009, DOI: 10.1111/j.1747-0285.2009.00883.x

  4. Quantitative Structure–Activity Relationship and Classification Analysis of Diaryl Ureas Against Vascular Endothelial Growth Factor Receptor-2 Kinase Using Linear and Non-Linear Models

    Chemical Biology & Drug Design

    Volume 73, Issue 6, June 2009, Pages: 644–654, Min Sun, Junqing Chen, Hongtao Wei, Shuangqing Yin, Yan Yang and Min Ji

    Article first published online : 17 APR 2009, DOI: 10.1111/j.1747-0285.2009.00814.x

  5. Synthesis, Kinetic Characterization and Metabolism of Diastereomeric 2-(1-(4-Phenoxyphenylsulfonyl)ethyl)thiiranes as Potent Gelatinase and MT1-MMP Inhibitors

    Chemical Biology & Drug Design

    Volume 74, Issue 6, December 2009, Pages: 535–546, Major Gooyit, Mijoon Lee, Dusan Hesek, Bill Boggess, Allen G. Oliver, Rafael Fridman, Shahriar Mobashery and Mayland Chang

    Article first published online : 12 OCT 2009, DOI: 10.1111/j.1747-0285.2009.00898.x

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    Circular Dichroism Techniques: Biomolecular and Nanostructural Analyses- A Review

    Chemical Biology & Drug Design

    Volume 74, Issue 2, August 2009, Pages: 101–120, Bijan Ranjbar and Pooria Gill

    Article first published online : 29 JUN 2009, DOI: 10.1111/j.1747-0285.2009.00847.x

  7. Prediction of primary structure deamidation rates of asparaginyl and glutaminyl peptides through steric and catalytic effects

    The Journal of Peptide Research

    Volume 63, Issue 5, May 2004, Pages: 437–448, N.E. Robinson and A.B. Robinson

    Article first published online : 10 MAY 2004, DOI: 10.1111/j.1399-3011.2004.00148.x

  8. Mechanistic-Based Descriptors for QSAR Study of Psychotropic Drug Toxicity

    Chemical Biology & Drug Design

    Volume 72, Issue 5, November 2008, Pages: 409–435, Mahnaz Esteki and Taghi Khayamian

    Article first published online : 16 OCT 2008, DOI: 10.1111/j.1747-0285.2008.00718.x

  9. ‘100 years of peptide synthesis’: ligation methods for peptide and protein synthesis with applications to β-peptide assemblies

    The Journal of Peptide Research

    Volume 65, Issue 2, February 2005, Pages: 229–260, T. Kimmerlin and D. Seebach

    Article first published online : 10 FEB 2005, DOI: 10.1111/j.1399-3011.2005.00214.x

  10. Somatostatin analogs

    The Journal of Peptide Research

    Volume 58, Issue 2, August 2001, Pages: 91–107, A. Janecka, M. Zubrzycka and T. Janecki

    Article first published online : 8 DEC 2008, DOI: 10.1034/j.1399-3011.2001.00873.x

  11. A Potent Gelatinase Inhibitor with Anti-Tumor-Invasive Activity and its Metabolic Disposition

    Chemical Biology & Drug Design

    Volume 73, Issue 2, February 2009, Pages: 189–202, Mijoon Lee, Giuseppe Celenza, Bill Boggess, Jennifer Blase, Qicun Shi, Marta Toth, M. Margarida Bernardo, William R. Wolter, Mark A. Suckow, Dusan Hesek, Bruce C. Noll, Rafael Fridman, Shahriar Mobashery and Mayland Chang

    Article first published online : 22 JAN 2009, DOI: 10.1111/j.1747-0285.2008.00750.x

  12. Atomic Interactions and Profile of Small Molecules Disrupting Protein–Protein Interfaces: the TIMBAL Database

    Chemical Biology & Drug Design

    Volume 74, Issue 5, November 2009, Pages: 457–467, Alícia P. Higueruelo, Adrian Schreyer, G. Richard J. Bickerton, Will R. Pitt, Colin R. Groom and Tom L. Blundell

    Article first published online : 6 OCT 2009, DOI: 10.1111/j.1747-0285.2009.00889.x

  13. Molecular dynamics simulation of the antimicrobial salivary peptide histatin-5 in water and in trifluoroethanol: a microscopic description of the water destructuring effect

    The Journal of Peptide Research

    Volume 58, Issue 1, July 2001, Pages: 45–55, M. Iovino, M. Falconi, A. Marcellini and A. Desideri

    Article first published online : 17 MAY 2002, DOI: 10.1034/j.1399-3011.2001.00885.x

  14. Pharmacophore Identification and Validation Study of CK2 Inhibitors Using CoMFA/CoMSIA

    Chemical Biology & Drug Design

    Volume 74, Issue 2, August 2009, Pages: 148–158, Mohammad Neaz Morshed, Muhammad Muddassar, Farhan Ahmad Pasha and Seung Joo Cho

    Article first published online : 26 JUN 2009, DOI: 10.1111/j.1747-0285.2009.00841.x

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    Vicinal Diamino Functionalities as Privileged Structural Elements in Biologically Active Compounds and Exploitation of their Synthetic Chemistry

    Chemical Biology & Drug Design

    Volume 67, Issue 2, February 2006, Pages: 101–114, S. R. S. Saibabu Kotti, Cody Timmons and Guigen Li

    Article first published online : 14 FEB 2006, DOI: 10.1111/j.1747-0285.2006.00347.x

  16. Rationalizing Protein–Ligand Interactions for PTP1B Inhibitors Using Computational Methods

    Chemical Biology & Drug Design

    Volume 74, Issue 6, December 2009, Pages: 582–595, Subhash Ajmani, Sudheer Karanam and Sudhir A. Kulkarni

    Article first published online : 12 OCT 2009, DOI: 10.1111/j.1747-0285.2009.00894.x

  17. Support Vector Machine-Based Quantitative Structure–Activity Relationship Study of Cholesteryl Ester Transfer Protein Inhibitors

    Chemical Biology & Drug Design

    Volume 73, Issue 5, May 2009, Pages: 558–571, Siavash Riahi, Eslam Pourbasheer, Mohammad Reza Ganjali and Parviz Norouzi

    Article first published online : 23 MAR 2009, DOI: 10.1111/j.1747-0285.2009.00800.x

  18. Molecular Shape Analysis of Antioxidant and Squalene Synthase Inhibitory Activities of Aromatic Tetrahydro-1,4-oxazine Derivatives

    Chemical Biology & Drug Design

    Volume 74, Issue 5, November 2009, Pages: 507–516, Kunal Roy, Indrani Mitra and Achintya Saha

    Article first published online : 28 SEP 2009, DOI: 10.1111/j.1747-0285.2009.00888.x

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    3D-QSAR Studies of JNK1 Inhibitors Utilizing Various Alignment Methods

    Chemical Biology & Drug Design

    Volume 79, Issue 1, January 2012, Pages: 53–67, Thirumurthy Madhavan, Jae Yoon Chung, Gugan Kothandan, Changdev G. Gadhe and Seung Joo Cho

    Article first published online : 4 NOV 2011, DOI: 10.1111/j.1747-0285.2011.01168.x

  20. Novel Naphthalimide–Benzoic Acid Conjugates as Potential Apoptosis-Inducing Agents: Design, Synthesis, and Biological Activity

    Chemical Biology & Drug Design

    Volume 78, Issue 6, December 2011, Pages: 941–947, Aibin Wu, Ping Mei, Yufang Xu and Xuhong Qian

    Article first published online : 29 SEP 2011, DOI: 10.1111/j.1747-0285.2011.01232.x