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There are 2265 results for: content related to: Comprehensive Analysis of Single- and Multi-Target Activity Cliffs Formed by Currently Available Bioactive Compounds

  1. Multitarget Tracking

    Standard Article

    Wiley Encyclopedia of Electrical and Electronics Engineering

    Ba-ngu Vo, Mahendra Mallick, Yaakov Bar-shalom, Stefano Coraluppi, Richard Osborne, Ronald Mahler and Ba-tuong Vo

    Published Online : 15 SEP 2015, DOI: 10.1002/047134608X.W8275

  2. Recent advances in the multitarget-directed ligands approach for the treatment of Alzheimer's disease

    Medicinal Research Reviews

    Volume 33, Issue 1, January 2013, Pages: 139–189, Rafael León, Antonio G. Garcia and José Marco-Contelles

    Article first published online : 26 JUL 2011, DOI: 10.1002/med.20248

  3. Application of GQSAR for Scaffold Hopping and Lead Optimization in Multitarget Inhibitors

    Molecular Informatics

    Volume 31, Issue 6-7, July 2012, Pages: 473–490, Subhash Ajmani and Sudhir A. Kulkarni

    Article first published online : 4 JUL 2012, DOI: 10.1002/minf.201100160

  4. Progress in the Analysis of Multiple Activity Profile of Screening Data Using Computational Approaches

    Drug Development Research

    Volume 75, Issue 5, August 2014, Pages: 313–323, Vicente F. Kuyoc-Carrillo and José L. Medina-Franco

    Article first published online : 27 AUG 2014, DOI: 10.1002/ddr.21209

  5. Potassium Channels: Structures, Diseases, and Modulators

    Chemical Biology & Drug Design

    Volume 83, Issue 1, January 2014, Pages: 1–26, Chuan Tian, Ruixin Zhu, Lixin Zhu, Tianyi Qiu, Zhiwei Cao and Tingguo Kang

    Article first published online : 23 DEC 2013, DOI: 10.1111/cbdd.12237

  6. History and Perspectives of A2A Adenosine Receptor Antagonists as Potential Therapeutic Agents

    Medicinal Research Reviews

    Volume 35, Issue 4, July 2015, Pages: 790–848, Delia Preti, Pier Giovanni Baraldi, Allan R. Moorman, Pier Andrea Borea and Katia Varani

    Article first published online : 27 MAR 2015, DOI: 10.1002/med.21344

  7. You have full text access to this OnlineOpen article
    PhIN: A Protein Pharmacology Interaction Network Database

    CPT: Pharmacometrics & Systems Pharmacology

    Volume 4, Issue 3, March 2015, Pages: 160–166, Z Wang, J Li, R Dang, L Liang and J Lin

    Article first published online : 18 MAR 2015, DOI: 10.1002/psp4.25

  8. Statistical Methods for Target Tracking

    Standard Article

    Wiley Encyclopedia of Computer Science and Engineering

    Simon Maskell

    Published Online : 16 MAR 2009, DOI: 10.1002/9780470050118.ecse645

  9. A novel multitarget tracking algorithm for Myosin VI protein molecules on actin filaments in TIRFM sequences

    Journal of Microscopy


    Article first published online : 10 AUG 2015, DOI: 10.1111/jmi.12299

  10. Exploring structure–activity data using the landscape paradigm

    Wiley Interdisciplinary Reviews: Computational Molecular Science

    Volume 2, Issue 6, November/December 2012, Pages: 829–841, Rajarshi Guha

    Article first published online : 24 APR 2012, DOI: 10.1002/wcms.1087

  11. Xanthones from Swertia mussotii as Multitarget-Directed Antidiabetic Agents


    Volume 9, Issue 7, July 2014, Pages: 1374–1377, Huan-Huan Zheng, Cui-Ting Luo, Prof. Heru Chen, Juan-Na Lin, Prof. Dr. Chun-Ling Ye, Shuang-Shuang Mao and Prof. Dr. Yu-Lin Li

    Article first published online : 31 JAN 2014, DOI: 10.1002/cmdc.201300507

  12. In Silico-Guided Strategies for the Discovery and Rationalization of Bioactive Natural Products

    Standard Article

    Encyclopedia of Analytical Chemistry

    Petra H. Pfisterer, Daniela Schuster, Judith M. Rollinger and Hermann Stuppner

    Published Online : 23 JUN 2014, DOI: 10.1002/9780470027318.a9942

  13. Nanobead electrokinetics: The enabling microfluidic platform for rapid multi-target pathogen detection

    AIChE Journal

    Volume 53, Issue 10, October 2007, Pages: 2486–2492, Hsueh-Chia Chang

    Article first published online : 10 AUG 2007, DOI: 10.1002/aic.11286

  14. Multitarget fragment-based design of novel inhibitors for AChE and SSAO/VAP-1 enzymes

    Journal of Chemometrics

    Volume 27, Issue 10, October 2013, Pages: 297–305, Sajjad Gharaghani, Taghi Khayamian and Malihe Ebrahimi

    Article first published online : 3 OCT 2013, DOI: 10.1002/cem.2556

  15. Virtual and In Vitro Bioassay Screening of Phytochemical Inhibitors from Flavonoids and Isoflavones Against Xanthine Oxidase and Cyclooxygenase-2 for Gout Treatment

    Chemical Biology & Drug Design

    Volume 81, Issue 4, April 2013, Pages: 537–544, Yadi Li, Christopher M. Frenz, Zhiwen Li, Mianhua Chen, Yurong Wang, Fengjuan Li, Cheng Luo, Jian Sun, Lars bohlin, Zhenjing Li, Hua Yang and Changlu Wang

    Article first published online : 28 MAR 2013, DOI: 10.1111/cbdd.1248

  16. 5-Benzylidenethiazolidin-4-ones as Multitarget Inhibitors of Bacterial Mur Ligases


    Volume 5, Issue 2, February 1, 2010, Pages: 286–295, Tihomir Tomašić, Nace Zidar, Andreja Kovač, Samo Turk, Mihael Simčič, Didier Blanot, Manica Müller-Premru, Metka Filipič, Simona Golič Grdadolnik, Anamarija Zega, Marko Anderluh, Stanislav Gobec, Danijel Kikelj and Lucija Peterlin Mašič

    Article first published online : 18 DEC 2009, DOI: 10.1002/cmdc.200900449

  17. The Bivalent Ligand Approach as a Tool for Improving the in vitro Anti-Alzheimer Multitarget Profile of Dimebon


    Volume 8, Issue 8, August 2013, Pages: 1276–1281, Dr. Michela Rosini, Dr. Elena Simoni, Dr. Manuela Bartolini, Dr. Elena Soriano, Prof. José Marco-Contelles, Prof. Vincenza Andrisano, Dr. Barbara Monti, Dr. Manfred Windisch, Dr. Birgit Hutter-Paier, Dr. David W. McClymont, Dr. Ian R. Mellor and Prof. Maria Laura Bolognesi

    Article first published online : 3 JUL 2013, DOI: 10.1002/cmdc.201300263

  18. Toward the Development of Dual-Targeted Glyceraldehyde-3-phosphate Dehydrogenase/Trypanothione Reductase Inhibitors against Trypanosoma brucei and Trypanosoma cruzi


    Volume 9, Issue 2, February 2014, Pages: 371–382, Prof. Dr. Federica Belluti, Elisa Uliassi, Giacomo Veronesi, Dr. Christian Bergamini, Dr. Marcel Kaiser, Prof. Dr. Reto Brun, Angelo Viola, Prof. Dr. Romana Fato, Prof. Dr. Paul A. M. Michels, Prof. Dr. R. Luise Krauth-Siegel, Prof. Dr. Andrea Cavalli and Prof. Dr. Maria Laura Bolognesi

    Article first published online : 8 JAN 2014, DOI: 10.1002/cmdc.201300399

  19. Toward an Efficient Approach to Identify Molecular Scaffolds Possessing Selective or Promiscuous Compounds

    Chemical Biology & Drug Design

    Volume 82, Issue 4, October 2013, Pages: 367–375, Austin B. Yongye and José L. Medina-Franco

    Article first published online : 10 SEP 2013, DOI: 10.1111/cbdd.12162

  20. You have free access to this content
    Chaperones as integrators of cellular networks: Changes of cellular integrity in stress and diseases

    IUBMB Life

    Volume 60, Issue 1, January 2008, Pages: 10–18, Robin Palotai, Máté S. Szalay and Péter Csermely

    Article first published online : 12 DEC 2007, DOI: 10.1002/iub.8