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There are 148942 results for: content related to: How blocking Raf activates the MAPK pathway

  1. You have full text access to this OnlineOpen article
    Identification of PLX4032-resistance mechanisms and implications for novel RAF inhibitors

    Pigment Cell & Melanoma Research

    Volume 27, Issue 2, March 2014, Pages: 253–262, Jaehyuk Choi, Sean F. Landrette, Tiffany Wang, Perry Evans, Antonella Bacchiocchi, Robert Bjornson, Elaine Cheng, Amy L. Stiegler, Symon Gathiaka, Orlando Acevedo, Titus J. Boggon, Michael Krauthammer, Ruth Halaban and Tian Xu

    Article first published online : 6 JAN 2014, DOI: 10.1111/pcmr.12197

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    Targeting RAS/RAF/MEK/ERK signaling in metastatic melanoma

    IUBMB Life

    Volume 65, Issue 9, September 2013, Pages: 748–758, Ao-Xue Wang and Xiao-Yi Qi

    Article first published online : 29 JUL 2013, DOI: 10.1002/iub.1193

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    KRAS and BRAF: drug targets and predictive biomarkers

    The Journal of Pathology

    Volume 223, Issue 2, January 2011, Pages: 220–230, Efsevia Vakiani and David B Solit

    Article first published online : 28 OCT 2010, DOI: 10.1002/path.2796

  4. Low-concentration vemurafenib induces the proliferation and invasion of human HaCaT keratinocytes through mitogen-activated protein kinase pathway activation

    The Journal of Dermatology

    Volume 42, Issue 9, September 2015, Pages: 881–888, Mi Ryung Roh, Jung Min Kim, Sang Hee Lee, Hong Sun Jang, Kyu Hyun Park, Kee Yang Chung and Sun Young Rha

    Article first published online : 5 JUN 2015, DOI: 10.1111/1346-8138.12950

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    BRAF, a target in melanoma

    Cancer

    Volume 116, Issue 21, 1 November 2010, Pages: 4902–4913, Keith T. Flaherty and Grant McArthur

    Article first published online : 13 JUL 2010, DOI: 10.1002/cncr.25261

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    A new era: melanoma genetics and therapeutics

    The Journal of Pathology

    Volume 223, Issue 2, January 2011, Pages: 242–251, Justin M Ko and David E Fisher

    Article first published online : 28 OCT 2010, DOI: 10.1002/path.2804

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    Role and therapeutic potential of PI3K-mTOR signaling in de novo resistance to BRAF inhibition

    Pigment Cell & Melanoma Research

    Volume 25, Issue 2, March 2012, Pages: 248–258, W. Deng, Y. N. Vashisht Gopal, A. Scott, G. Chen, S. E. Woodman and M. A. Davies

    Article first published online : 12 JAN 2012, DOI: 10.1111/j.1755-148X.2011.00950.x

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    Society for Melanoma Research 2014 Congress

    Pigment Cell & Melanoma Research

    Volume 27, Issue 6, November 2014, Pages: 1169–1241,

    Article first published online : 23 OCT 2014, DOI: 10.1111/pcmr.12317

  9. Developing melanoma therapeutics: overview and update

    Wiley Interdisciplinary Reviews: Systems Biology and Medicine

    Volume 5, Issue 3, May/June 2013, Pages: 257–271, John B. Korman and David E. Fisher

    Article first published online : 13 FEB 2013, DOI: 10.1002/wsbm.1210

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    That which does not kill me makes me stronger; combining ERK1/2 pathway inhibitors and BH3 mimetics to kill tumour cells and prevent acquired resistance

    British Journal of Pharmacology

    Volume 169, Issue 8, August 2013, Pages: 1708–1722, Matthew J Sale and Simon J Cook

    Article first published online : 26 JUL 2013, DOI: 10.1111/bph.12220

  11. Paradoxical oncogenesis: are all BRAF inhibitors equal?

    Pigment Cell & Melanoma Research

    Volume 26, Issue 5, September 2013, Pages: 611–615, Alexander M. Menzies, Richard F. Kefford and Georgina V. Long

    Article first published online : 19 JUL 2013, DOI: 10.1111/pcmr.12132

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    2011 International Melanoma Congress

    Pigment Cell & Melanoma Research

    Volume 24, Issue 5, October 2011, Pages: 990–1075,

    Article first published online : 10 OCT 2011, DOI: 10.1111/j.1755-148X.2011.00909.x

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    Mechanisms of intrinsic and acquired resistance to kinase-targeted therapies

    Pigment Cell & Melanoma Research

    Volume 25, Issue 6, November 2012, Pages: 819–831, Shubha Bagrodia, Tod Smeal and Robert T. Abraham

    Article first published online : 14 SEP 2012, DOI: 10.1111/pcmr.12007

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    Melanoma 2010 Congress

    Pigment Cell & Melanoma Research

    Volume 23, Issue 6, December 2010, Pages: 874–1004,

    Article first published online : 13 OCT 2010, DOI: 10.1111/j.1755-148X.2010.00767.x

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    Functional characterization of the novel BRAF complex mutation, BRAFV600delinsYM, identified in papillary thyroid carcinoma

    International Journal of Cancer

    Volume 132, Issue 3, 1 February 2013, Pages: 738–743, Michiko Matsuse, Norisato Mitsutake, Susumu Tanimura, Tomoo Ogi, Eijun Nishihara, Mitsuyoshi Hirokawa, Cesar S. Fuziwara, Vladimir A. Saenko, Keiji Suzuki, Akira Miyauchi and Shunichi Yamashita

    Article first published online : 21 JUL 2012, DOI: 10.1002/ijc.27709

  16. The broad-spectrum receptor tyrosine kinase inhibitor dovitinib suppresses growth of BRAF-mutant melanoma cells in combination with other signaling pathway inhibitors

    Pigment Cell & Melanoma Research

    Volume 28, Issue 4, July 2015, Pages: 417–430, Casey G. Langdon, Matthew A. Held, James T. Platt, Katrina Meeth, Pinar Iyidogan, Ramanaiah Mamillapalli, Andrew B. Koo, Michael Klein, Zongzhi Liu, Marcus W. Bosenberg and David F. Stern

    Article first published online : 6 MAY 2015, DOI: 10.1111/pcmr.12376

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    Inducible expression of V600EBraf using tyrosinase-driven Cre recombinase results in embryonic lethality

    Pigment Cell & Melanoma Research

    Volume 23, Issue 1, February 2010, Pages: 112–120, Nathalie Dhomen, Silvy Da Rocha Dias, Robert Hayward, Lesley Ogilvie, Douglas Hedley, Veronique Delmas, Afshan McCarthy, Deborah Henderson, Caroline J. Springer, Catrin Pritchard, Lionel Larue and Richard Marais

    Article first published online : 11 DEC 2009, DOI: 10.1111/j.1755-148X.2009.00662.x

    Corrected by:

    Erratum

    Vol. 23, Issue 2, 302, Article first published online: 2 MAR 2010

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    Oncogenic RAF: a brief history of time

    Pigment Cell & Melanoma Research

    Volume 23, Issue 6, December 2010, Pages: 760–762, David Solit and Neal Rosen

    Article first published online : 13 OCT 2010, DOI: 10.1111/j.1755-148X.2010.00779.x

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    New drug targets in metastatic melanoma

    The Journal of Pathology

    Volume 232, Issue 2, January 2014, Pages: 134–141, Blanca Homet and Antoni Ribas

    Article first published online : 10 DEC 2013, DOI: 10.1002/path.4259

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    Society for Melanoma Research 2013 Congress

    Pigment Cell & Melanoma Research

    Volume 26, Issue 6, November 2013, Pages: 932–1019,

    Article first published online : 24 OCT 2013, DOI: 10.1111/pcmr.12166