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There are 6466 results for: content related to: Clinical relevance of SKP2 alterations in metastatic melanoma

  1. You have free access to this content
    Association of human CUL-1 and ubiquitin-conjugating enzyme CDC34 with the F-box protein p45SKP2: evidence for evolutionary conservation in the subunit composition of the CDC34–SCF pathway

    The EMBO Journal

    Volume 17, Issue 2, January 15, 1998, Pages: 368–383, Joanna Lisztwan, Alain Marti, Hedwig Sutterlüty, Matthias Gstaiger, Christiane Wirbelauer and Wilhelm Krek

    Article first published online : 15 JAN 1998, DOI: 10.1093/emboj/17.2.368

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    The F-box protein Skp2 is a ubiquitylation target of a Cul1-based core ubiquitin ligase complex: evidence for a role of Cul1 in the suppression of Skp2 expression in quiescent fibroblasts

    The EMBO Journal

    Volume 19, Issue 20, October 16, 2000, Pages: 5362–5375, Christiane Wirbelauer, Hedwig Sutterlüty, Marc Blondel, Mathias Gstaiger, Matthias Peter, Francoise Reymond and Wilhelm Krek

    Article first published online : 16 OCT 2000, DOI: 10.1093/emboj/19.20.5362

  3. You have free access to this content
    Prodigiosin down-regulates SKP2 to induce p27KIP1 stabilization and antiproliferation in human lung adenocarcinoma cells

    British Journal of Pharmacology

    Volume 166, Issue 7, August 2012, Pages: 2095–2108, Hsin-Ying Hsieh, Jeng-Jer Shieh, Chun-Jung Chen, Mu-Yun Pan, Shu-Yi Yang, Shin-Chang Lin, Jo-Shu Chang, Alan Yueh-Luen Lee and Chia-Che Chang

    Article first published online : 9 JUL 2012, DOI: 10.1111/j.1476-5381.2012.01921.x

  4. You have free access to this content
    Targeted disruption of Skp2 results in accumulation of cyclin E and p27Kip1, polyploidy and centrosome overduplication

    The EMBO Journal

    Volume 19, Issue 9, May 2, 2000, Pages: 2069–2081, Keiko Nakayama, Hiroyasu Nagahama, Yohji A. Minamishima, Masaki Matsumoto, Ikuo Nakamichi, Kyoko Kitagawa, Michiko Shirane, Ryosuke Tsunematsu, Tadasuke Tsukiyama, Noriko Ishida, Masatoshi Kitagawa, Kei-ichi Nakayama and Shigetsugu Hatakeyama

    Article first published online : 2 MAY 2000, DOI: 10.1093/emboj/19.9.2069

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    The F Box Protein S Phase Kinase-associated Protein 2 Regulates Adipose Mass and Adipocyte Number in Vivo


    Volume 15, Issue 6, June 2007, Pages: 1400–1408, Paul S. Cooke, Denise R. Holsberger, Melissa A. Cimafranca, Daryl D. Meling, Charity M. Beals, Keiko Nakayama, Keiichi I. Nakayama and Hiroaki Kiyokawa

    Article first published online : 6 SEP 2012, DOI: 10.1038/oby.2007.168

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    Phosphorylation of Skp2 regulated by CDK2 and Cdc14B protects it from degradation by APCCdh1 in G1 phase

    The EMBO Journal

    Volume 27, Issue 4, February 20, 2008, Pages: 679–691, Geneviève Rodier, Philippe Coulombe, Pierre-Luc Tanguay, Christel Boutonnet and Sylvain Meloche

    Article first published online : 31 JAN 2008, DOI: 10.1038/emboj.2008.6

  7. Skp2 regulates androgen receptor through ubiquitin-mediated degradation independent of Akt/mTOR pathways in prostate cancer

    The Prostate

    Volume 74, Issue 4, April 2014, Pages: 421–432, Bo Li, Wenfu Lu, Qing Yang, Xiuping Yu, Robert J. Matusik and Zhenbang Chen

    Article first published online : 17 DEC 2013, DOI: 10.1002/pros.22763

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    Molecular dynamics simulations elucidate the mode of protein recognition by Skp1 and the F-box domain in the SCF complex

    Proteins: Structure, Function, and Bioinformatics

    Volume 84, Issue 1, January 2016, Pages: 159–171, Sarath Chandra Dantu, Nitin Nathubhai Kachariya and Ashutosh Kumar

    Article first published online : 19 DEC 2015, DOI: 10.1002/prot.24963

  9. SKP2 Overexpression Is Associated With Increased Serine 10 Phosphorylation of p27 (pSer10p27) in Triple-Negative Breast Cancer

    Journal of Cellular Physiology

    Volume 229, Issue 9, September 2014, Pages: 1160–1169, Katerina D. Fagan-Solis, Brian T. Pentecost, Joseph M. Gozgit, Brooke A. Bentley, Sharon M. Marconi, Christopher N. Otis, Douglas L. Anderton, Sallie Smith Schneider and Kathleen F. Arcaro

    Article first published online : 23 MAY 2014, DOI: 10.1002/jcp.24545

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    Characterization of the cullin and F-box protein partner Skp1

    FEBS Letters

    Volume 438, Issue 3, November 06, 1998, Pages: 183–189, Raymond W.M. Ng, Talha Arooz, Cain H. Yam, Iris W.Y. Chan, Anita W.S. Lau and Randy Y.C. Poon

    Article first published online : 24 NOV 1998, DOI: 10.1016/S0014-5793(98)01299-X

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    Impaired ovarian development and reduced fertility in female mice deficient in Skp2

    Journal of Anatomy

    Volume 218, Issue 6, June 2011, Pages: 668–677, Abbas Fotovati, Samah Abu-Ali, Keiko Nakayama and Keiichi I. Nakayama

    Article first published online : 31 MAR 2011, DOI: 10.1111/j.1469-7580.2011.01370.x

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    Oncogenic properties and prognostic implications of the ubiquitin ligase Skp2 in cancer


    Volume 112, Issue 7, 1 April 2008, Pages: 1415–1424, Dan D. Hershko

    Article first published online : 7 FEB 2008, DOI: 10.1002/cncr.23317

  13. A Chemical Inhibitor of the Skp2/p300 Interaction that Promotes p53-Mediated Apoptosis

    Angewandte Chemie International Edition

    Volume 55, Issue 2, January 11, 2016, Pages: 602–606, Dr. Misook Oh, Dr. Ji Hoon Lee, Heejo Moon, Yu-Jung Hyun and Prof. Dr. Hyun-Suk Lim

    Article first published online : 23 NOV 2015, DOI: 10.1002/anie.201508716

  14. You have free access to this content
    Skp2 induction and phosphorylation is associated with the late G1 phase of proliferating rat hepatocytes

    FEBS Letters

    Volume 452, Issue 3, June 11, 1999, Pages: 247–253, Marc Bilodeau, Hélène Talarmin, Gennady Ilyin, Claude Rescan, Denise Glaise, Sandrine Cariou, Pascal Loyer, Christiane Guguen-Guillouzo and Georges Baffet

    Article first published online : 11 JUN 1999, DOI: 10.1016/S0014-5793(99)00629-8

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    An in vivo study of Cdh1/APC in breast cancer formation

    International Journal of Cancer

    Volume 125, Issue 4, 15 August 2009, Pages: 826–836, Takeo Fujita, Weijun Liu, Hiroyoshi Doihara and Yong Wan

    Article first published online : 27 FEB 2009, DOI: 10.1002/ijc.24399

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    SKP2A, an F-box protein that regulates cell division, is degraded via the ubiquitin pathway

    The Plant Journal

    Volume 53, Issue 5, March 2008, Pages: 828–841, Silvia Jurado, Sara Díaz-Triviño, Zamira Abraham, Concepción Manzano, Crisanto Gutierrez and Carlos del Pozo

    Article first published online : 23 NOV 2007, DOI: 10.1111/j.1365-313X.2007.03378.x

  17. You have free access to this content
    Hormonal induction of adipogenesis induces Skp2 expression through PI3K and MAPK pathways

    Journal of Cellular Biochemistry

    Volume 100, Issue 1, 1 January 2007, Pages: 204–216, Corinth A. Auld, Carla D. Caccia and Ron F. Morrison

    Article first published online : 21 AUG 2006, DOI: 10.1002/jcb.21063

  18. Androgens repress expression of the f-box protein Skp2 via p107 dependent and independent mechanisms in LNCaP prostate cancer cells

    The Prostate

    Volume 72, Issue 2, 1 February 2012, Pages: 225–232, Jingting Jiang, Yunqian Pan, Kevin M. Regan, Changping Wu, Xueguang Zhang, Donald J. Tindall and Haojie Huang

    Article first published online : 31 MAY 2011, DOI: 10.1002/pros.21430

  19. Nuclear expression of S-phase kinase–associated protein 2 predicts poor prognosis of hepatocellular carcinoma


    Volume 120, Issue 5, May 2012, Pages: 349–357, EUN SHIN, SOO-HEE KIM, HAE-YEON JEONG, JA-JUNE JANG and KYUNGBUN LEE

    Article first published online : 11 NOV 2011, DOI: 10.1111/j.1600-0463.2011.02838.x

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    Skp2B attenuates p53 function by inhibiting prohibitin

    EMBO reports

    Volume 11, Issue 3, March 2010, Pages: 220–225, Harish Chander, Max Halpern, Lois Resnick-Silverman, James J Manfredi and Doris Germain

    Article first published online : 5 FEB 2010, DOI: 10.1038/embor.2010.2