Search Results

There are 31603 results for: content related to: Melanoma and viagra: an unexpected connection

  1. You have free access to this content
    Genomic origin and transcriptional regulation of two variants of cGMP-binding cGMP-specific phosphodiesterases

    European Journal of Biochemistry

    Volume 262, Issue 3, June 1999, Pages: 866–873, Jun Kotera, Kotomi Fujishige, Yuji Imai, Eri Kawai, Hideo Michibata, Hiroyuki Akatsuka, Noriyuki Yanaka and Kenji Omori

    Version of Record online : 25 DEC 2001, DOI: 10.1046/j.1432-1327.1999.00450.x

  2. Identification of murine phosphodiesterase 5A isoforms and their functional characterization in HL-1 cardiac cell line

    Journal of Cellular Physiology

    Federica Campolo, Alessandra Zevini, Silvia Cardarelli, Lucia Monaco, Federica Barbagallo, Manuela Pellegrini, Marisa Cornacchione, Antonio Di Grazia, Valeria De Arcangelis, Daniele Gianfrilli, Mauro Giorgi, Andrea Lenzi, Andrea M. Isidori and Fabio Naro

    Version of Record online : 18 MAY 2017, DOI: 10.1002/jcp.25880

  3. You have free access to this content
    Interaction of caspase-3 with the cyclic GMP binding cyclic GMP specific phosphodiesterase (PDE5a1)

    European Journal of Biochemistry

    Volume 270, Issue 5, March 2003, Pages: 962–970, Mhairi J. Frame, Rothwelle Tate, David R. Adams, Keith M. Morgan, M. D. Houslay, Peter Vandenabeele and Nigel J. Pyne

    Version of Record online : 10 SEP 2003, DOI: 10.1046/j.1432-1033.2003.03464.x

  4. You have free access to this content
    Molecular Pharmacotherapeutic Targeting of PDE5 for Preservation of Penile Health

    Journal of Andrology

    Volume 29, Issue 1, January-February 2008, Pages: 3–14, Arthur L. Burnett

    Version of Record online : 2 JAN 2013, DOI: 10.2164/jandrol.107.003483

  5. ORIGINAL RESEARCH: Phosphodiesterase Type 5 Regulation in the Penile Corpora Cavernosa

    The Journal of Sexual Medicine

    Volume 6, Issue S3, March 2009, Pages: 203–209, Ching-Shwun Lin

    Version of Record online : 24 FEB 2009, DOI: 10.1111/j.1743-6109.2008.01179.x

  6. You have free access to this content
    PDE5 is converted to an activated state upon cGMP binding to the GAF A domain

    The EMBO Journal

    Volume 22, Issue 3, February 3, 2003, Pages: 469–478, Sergei D. Rybalkin, Irina G. Rybalkina, Masami Shimizu-Albergine, Xiao-Bo Tang and Joseph A. Beavo

    Version of Record online : 3 FEB 2003, DOI: 10.1093/emboj/cdg051

  7. You have free access to this content
    Activation of PDE2 and PDE5 by specific GAF ligands: delayed activation of PDE5

    British Journal of Pharmacology

    Volume 161, Issue 7, December 2010, Pages: 1645–1660, Ronald Jäger, Frank Schwede, Hans-Gottfried Genieser, Doris Koesling and Michael Russwurm

    Version of Record online : 5 NOV 2010, DOI: 10.1111/j.1476-5381.2010.00977.x

  8. Phosphodiesterase Type 5 Is Not Upregulated by Tadalafil in Cultures of Human Penile Cells

    The Journal of Sexual Medicine

    Volume 3, Issue 1, January 2006, Pages: 84–95, Dolores Vernet, Thomas Magee, Ansha Qian, Gaby Nolazco, Jacob Rajfer and Nestor Gonzalez-Cadavid

    Version of Record online : 5 JAN 2006, DOI: 10.1111/j.1743-6109.2005.00197.x

  9. You have free access to this content
    Increased expression of the cGMP-inhibited cAMP-specific (PDE3) and cGMP binding cGMP-specific (PDE5) phosphodiesterases in models of pulmonary hypertension

    British Journal of Pharmacology

    Volume 137, Issue 8, December 2002, Pages: 1187–1194, Fiona Murray, Margaret R MacLean and Nigel J Pyne

    Version of Record online : 29 JAN 2009, DOI: 10.1038/sj.bjp.0704984

  10. You have free access to this content
    Modeling and mutational analysis of the GAF domain of the cGMP-binding, cGMP-specific phosphodiesterase, PDE5

    FEBS Letters

    Volume 539, Issue 1-3, March 27, 2003, Pages: 161–166, Shailaja Sopory, S Balaji, N Srinivasan and Sandhya S Visweswariah

    Version of Record online : 11 MAR 2003, DOI: 10.1016/S0014-5793(03)00219-9

  11. Expression of PDE5 splice variants during ontogenesis of chick dorsal root ganglia

    Journal of Neuroscience Research

    Volume 78, Issue 6, 15 December 2004, Pages: 815–823, Daniela Giordano, Mauro Giorgi, Ada Maria Tata, Anna Modica and Gabriella Augusti-Tocco

    Version of Record online : 25 OCT 2004, DOI: 10.1002/jnr.20337

  12. You have free access to this content
    Structural basis of phosphodiesterase 6 inhibition by the C-terminal region of the γ-subunit

    The EMBO Journal

    Volume 28, Issue 22, November 18, 2009, Pages: 3613–3622, Brandy Barren, Lokesh Gakhar, Hakim Muradov, Kimberly K Boyd, S Ramaswamy and Nikolai O Artemyev

    Version of Record online : 1 OCT 2009, DOI: 10.1038/emboj.2009.284

  13. Suppression of cyclic GMP-specific phosphodiesterase 5 promotes apoptosis and inhibits growth in HT29 cells

    Journal of Cellular Biochemistry

    Volume 94, Issue 2, 1 February 2005, Pages: 336–350, Bing Zhu, Lakshmi Vemavarapu, W. Joseph Thompson and Samuel J. Strada

    Version of Record online : 3 NOV 2004, DOI: 10.1002/jcb.20286

  14. You have free access to this content
    Cyclic nucleotide phosphodiesterase (PDE) isozymes as targets of the intracellular signalling network: benefits of PDE inhibitors in various diseases and perspectives for future therapeutic developments

    British Journal of Pharmacology

    Volume 165, Issue 5, March 2012, Pages: 1288–1305, Thérèse Keravis and Claire Lugnier

    Version of Record online : 10 FEB 2012, DOI: 10.1111/j.1476-5381.2011.01729.x

  15. SOP Conservative (Medical and Mechanical) Treatment of Erectile Dysfunction

    The Journal of Sexual Medicine

    Volume 10, Issue 1, January 2013, Pages: 130–171, Hartmut Porst, Arthur Burnett, Gerald Brock, Hussein Ghanem, Francois Giuliano, Sidney Glina, Wayne Hellstrom, Antonio Martin-Morales, Andrea Salonia, Ira Sharlip and the ISSM Standards Committee for Sexual Medicine

    Version of Record online : 23 JAN 2013, DOI: 10.1111/jsm.12023

  16. You have free access to this content
    Contractile agonists attenuate cGMP levels by stimulating phosphorylation of cGMP-specific PDE5; an effect mediated by RhoA/PKC-dependent inhibition of protein phosphatase 1

    British Journal of Pharmacology

    Volume 153, Issue 6, March 2008, Pages: 1214–1224, K S Murthy

    Version of Record online : 29 JAN 2009, DOI: 10.1038/sj.bjp.0707686

  17. You have free access to this content
    The human phosphodiesterase PDE10A gene

    European Journal of Biochemistry

    Volume 267, Issue 19, October 2000, Pages: 5943–5951, Kotomi Fujishige, Jun Kotera, Keizo Yuasa and Kenji Omori

    Version of Record online : 25 DEC 2001, DOI: 10.1046/j.1432-1327.2000.01661.x

  18. You have free access to this content
    Phosphodiesterase type 5 inhibitors for erectile dysfunction

    BJU International

    Volume 96, Issue 3, August 2005, Pages: 257–280, Culley C. Carson and Tom F. Lue

    Version of Record online : 24 JUL 2005, DOI: 10.1111/j.1464-410X.2005.05614.x

  19. Nitric Oxide-Induced Changes in Endothelial Expression of Phosphodiesterases 2, 3, and 5

    Headache: The Journal of Head and Face Pain

    Volume 50, Issue 3, March 2010, Pages: 431–441, Christoph J. Schankin, Lars S. Kruse, Veronika M. Reinisch, Steffen Jungmann, Julie C. Kristensen, Stefan Grau, Uta Ferrari, Inga Sinicina, Roland Goldbrunner, Andreas Straube and Christina Kruuse

    Version of Record online : 14 SEP 2009, DOI: 10.1111/j.1526-4610.2009.01512.x

  20. You have free access to this content
    Genomic organization of the human phosphodiesterase PDE11A gene

    European Journal of Biochemistry

    Volume 268, Issue 1, January 2001, Pages: 168–178, Keizo Yuasa, Yutaka Kanoh, Katsuzumi Okumura and Kenji Omori

    Version of Record online : 20 DEC 2001, DOI: 10.1046/j.1432-1327.2001.01866.x